标题
Recent insights into the cellular and molecular determinants of aging
作者
关键词
-
出版物
JOURNAL OF CELL SCIENCE
Volume 131, Issue 3, Pages jcs210831
出版商
The Company of Biologists
发表日期
2018-02-08
DOI
10.1242/jcs.210831
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Autophagy maintains the metabolism and function of young and old stem cells
- (2017) Theodore T. Ho et al. NATURE
- Cytosolic proteostasis through importing of misfolded proteins into mitochondria
- (2017) Linhao Ruan et al. NATURE
- Therapeutic reduction of ataxin-2 extends lifespan and reduces pathology in TDP-43 mice
- (2017) Lindsay A. Becker et al. NATURE
- Human umbilical cord plasma proteins revitalize hippocampal function in aged mice
- (2017) Joseph M. Castellano et al. NATURE
- Antisense oligonucleotide therapy for spinocerebellar ataxia type 2
- (2017) Daniel R. Scoles et al. NATURE
- Senescent cells: an emerging target for diseases of ageing
- (2017) Bennett G. Childs et al. NATURE REVIEWS DRUG DISCOVERY
- TMEM175 deficiency impairs lysosomal and mitochondrial function and increases α-synuclein aggregation
- (2017) Sarah Jinn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mitochondrial Sirtuins and Molecular Mechanisms of Aging
- (2017) Robert A.H. van de Ven et al. TRENDS IN MOLECULAR MEDICINE
- A new role for oxidative stress in aging: The accelerated aging phenotype in Sod1−/ − mice is correlated to increased cellular senescence
- (2017) Yiqiang Zhang et al. Redox Biology
- Unbiased analysis of senescence associated secretory phenotype (SASP) to identify common components following different genotoxic stresses
- (2016) Servet Özcan et al. Aging-US
- Amyloid-like Self-Assembly of a Cellular Compartment
- (2016) Elvan Boke et al. CELL
- Epigenetic Mechanisms of Longevity and Aging
- (2016) Payel Sen et al. CELL
- Metabolic Control of Longevity
- (2016) Carlos López-Otín et al. CELL
- Mitochondrial SIRT3 Mediates Adaptive Responses of Neurons to Exercise and Metabolic and Excitatory Challenges
- (2016) Aiwu Cheng et al. Cell Metabolism
- A Ribosomal Perspective on Proteostasis and Aging
- (2016) Kristan K. Steffen et al. Cell Metabolism
- Altered Proteins in the Aging Brain
- (2016) Adila Elobeid et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Failed Alzheimer’s trial does not kill leading theory of disease
- (2016) Alison Abbott et al. NATURE
- Decoding ALS: from genes to mechanism
- (2016) J. Paul Taylor et al. NATURE
- Autophagy maintains stemness by preventing senescence
- (2016) Laura García-Prat et al. NATURE
- Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
- (2016) Darren J. Baker et al. NATURE
- In vivo aspects of protein folding and quality control
- (2016) D. Balchin et al. SCIENCE
- Anti-Aging Strategies Based on Cellular Reprogramming
- (2016) Alejandro Ocampo et al. TRENDS IN MOLECULAR MEDICINE
- BubR1 alterations that reinforce mitotic surveillance act against aneuploidy and cancer
- (2016) Robbyn L Weaver et al. eLife
- Heat shock proteins in long-lived worms and mice with insulin/insulin-Like signaling mutations
- (2016) William R. Swindell Aging-US
- Genetic factors associated with longevity: A review of recent findings
- (2015) Aladdin H. Shadyab et al. AGEING RESEARCH REVIEWS
- Asymmetric damage segregation at cell division via protein aggregate fusion and attachment to organelles
- (2015) Miguel Coelho et al. BIOESSAYS
- Type 1 interferons contribute to the clearance of senescent cell
- (2015) Yuliya V Katlinskaya et al. CANCER BIOLOGY & THERAPY
- Early Telomerase Inactivation Accelerates Aging Independently of Telomere Length
- (2015) Zhengwei Xie et al. CELL
- Organization of the Mammalian Metabolome according to Organ Function, Lineage Specialization, and Longevity
- (2015) Siming Ma et al. Cell Metabolism
- Essential role for autophagy in life span extension
- (2015) Frank Madeo et al. JOURNAL OF CLINICAL INVESTIGATION
- The C9orf72 repeat expansion disrupts nucleocytoplasmic transport
- (2015) Ke Zhang et al. NATURE
- GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport
- (2015) Brian D. Freibaum et al. NATURE
- Mitochondrial DNA stress primes the antiviral innate immune response
- (2015) A. Phillip West et al. NATURE
- Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice
- (2015) Jianhui Chang et al. NATURE MEDICINE
- Proteostasis and aging
- (2015) Susmita Kaushik et al. NATURE MEDICINE
- Genomic integrity and the ageing brain
- (2015) Hei-man Chow et al. NATURE REVIEWS NEUROSCIENCE
- Stem cells and healthy aging
- (2015) M. A. Goodell et al. SCIENCE
- Cytoplasmic protein aggregates interfere with nucleocytoplasmic transport of protein and RNA
- (2015) A. C. Woerner et al. SCIENCE
- Lysosomal signaling molecules regulate longevity in Caenorhabditis elegans
- (2015) A. Folick et al. SCIENCE
- Asymmetric apportioning of aged mitochondria between daughter cells is required for stemness
- (2015) P. Katajisto et al. SCIENCE
- Histone modifications change with age, dietary restriction and rapamycin treatment in mouse brain
- (2015) Huan Gong et al. Oncotarget
- Genome-Wide Scan Informed by Age-Related Disease Identifies Loci for Exceptional Human Longevity
- (2015) Kristen Fortney et al. PLoS Genetics
- The ER Stress Surveillance (ERSU) pathway regulates daughter cell ER protein aggregate inheritance
- (2015) Francisco J Piña et al. eLife
- Targeting senescent cells enhances adipogenesis and metabolic function in old age
- (2015) Ming Xu et al. eLife
- Longevity pathways converge on autophagy genes to regulate life span inCaenorhabditis elegans
- (2014) Márton L. Tóth et al. Autophagy
- Organelle-Based Aggregation and Retention of Damaged Proteins in Asymmetrically Dividing Cells
- (2014) Chuankai Zhou et al. CELL
- The role of PI3K/AKT/mTOR pathway in the modulation of autophagy and the clearance of protein aggregates in neurodegeneration
- (2014) David Heras-Sandoval et al. CELLULAR SIGNALLING
- Running Forward
- (2014) Glenn C. Rowe et al. CIRCULATION
- GWAS of Longevity in CHARGE Consortium Confirms APOE and FOXO3 Candidacy
- (2014) Linda Broer et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Formation of α-synuclein Lewy neurite–like aggregates in axons impedes the transport of distinct endosomes
- (2014) Laura A. Volpicelli-Daley et al. MOLECULAR BIOLOGY OF THE CELL
- Mitochondrial UPR-regulated innate immunity provides resistance to pathogen infection
- (2014) Mark W. Pellegrino et al. NATURE
- REST and stress resistance in ageing and Alzheimer’s disease
- (2014) Tao Lu et al. NATURE
- Mitochondrial form and function
- (2014) Jonathan R. Friedman et al. NATURE
- The role of senescent cells in ageing
- (2014) Jan M. van Deursen NATURE
- Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice
- (2014) Saul A Villeda et al. NATURE MEDICINE
- Cellular senescence: from physiology to pathology
- (2014) Daniel Muñoz-Espín et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Identification of long-lived proteins retained in cells undergoing repeated asymmetric divisions
- (2014) Nathaniel H. Thayer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Vascular and Neurogenic Rejuvenation of the Aging Mouse Brain by Young Systemic Factors
- (2014) L. Katsimpardi et al. SCIENCE
- The role of protein clearance mechanisms in organismal ageing and age-related diseases
- (2014) David Vilchez et al. Nature Communications
- Molecular Links between Caloric Restriction and Sir2/SIRT1 Activation
- (2014) Yu Wang Diabetes & Metabolism Journal
- Accelerating the clearance of mutant huntingtin protein aggregates through autophagy induction by europium hydroxide nanorods
- (2013) Peng-Fei Wei et al. BIOMATERIALS
- The Hallmarks of Aging
- (2013) Carlos López-Otín et al. CELL
- Identification of Long-Lived Proteins Reveals Exceptional Stability of Essential Cellular Structures
- (2013) Brandon H. Toyama et al. CELL
- Sirt1 Extends Life Span and Delays Aging in Mice through the Regulation of Nk2 Homeobox 1 in the DMH and LH
- (2013) Akiko Satoh et al. Cell Metabolism
- Historical landmarks of autophagy research
- (2013) Yoshinori Ohsumi CELL RESEARCH
- Premature aging in telomerase-deficient zebrafish
- (2013) M. Anchelin et al. Disease Models & Mechanisms
- Reactive oxygen species and the free radical theory of aging
- (2013) Stefan I. Liochev FREE RADICAL BIOLOGY AND MEDICINE
- The role of mitochondria in aging
- (2013) Ana Bratic et al. JOURNAL OF CLINICAL INVESTIGATION
- Hypothalamic programming of systemic ageing involving IKK-β, NF-κB and GnRH
- (2013) Guo Zhang et al. NATURE
- Self-propagation of pathogenic protein aggregates in neurodegenerative diseases
- (2013) Mathias Jucker et al. NATURE
- SIRT3 Reverses Aging-Associated Degeneration
- (2013) Katharine Brown et al. Cell Reports
- Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer
- (2012) Bruno Bernardes de Jesus et al. EMBO Molecular Medicine
- Protein aggregation and misfolding: good or evil?
- (2012) Annalisa Pastore et al. JOURNAL OF PHYSICS-CONDENSED MATTER
- An early age increase in vacuolar pH limits mitochondrial function and lifespan in yeast
- (2012) Adam L. Hughes et al. NATURE
- Increased expression of BubR1 protects against aneuploidy and cancer and extends healthy lifespan
- (2012) Darren J. Baker et al. NATURE CELL BIOLOGY
- Telomere length in early life predicts lifespan
- (2012) B. J. Heidinger et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Exome Sequencing and Functional Analysis Identifies BANF1 Mutation as the Cause of a Hereditary Progeroid Syndrome
- (2011) Xose S. Puente et al. AMERICAN JOURNAL OF HUMAN GENETICS
- SQSTM1 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis
- (2011) Faisal Fecto ARCHIVES OF NEUROLOGY
- Overexpression of eIF-5A2 in mice causes accelerated organismal aging by increasing chromosome instability
- (2011) Muhan Chen et al. BMC CANCER
- Autophagy and Aging
- (2011) David C. Rubinsztein et al. CELL
- MAVS Forms Functional Prion-like Aggregates to Activate and Propagate Antiviral Innate Immune Response
- (2011) Fajian Hou et al. CELL
- A mouse model of accelerated liver aging caused by a defect in DNA repair
- (2011) Siobhán Q. Gregg et al. HEPATOLOGY
- Recapitulation of premature ageing with iPSCs from Hutchinson–Gilford progeria syndrome
- (2011) Guang-Hui Liu et al. NATURE
- Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans
- (2011) Eric L. Greer et al. NATURE
- Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
- (2011) Darren J. Baker et al. NATURE
- Proteasomes and protein conjugation across domains of life
- (2011) Julie Maupin-Furlow NATURE REVIEWS MICROBIOLOGY
- Prion-like acceleration of a synucleinopathy in a transgenic mouse model
- (2011) Anne-Laure Mougenot et al. NEUROBIOLOGY OF AGING
- Histone H4 lysine 16 hypoacetylation is associated with defective DNA repair and premature senescence in Zmpste24-deficient mice
- (2011) V. Krishnan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Endurance exercise rescues progeroid aging and induces systemic mitochondrial rejuvenation in mtDNA mutator mice
- (2011) A. Safdar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The life span-prolonging effect of Sirtuin-1 is mediated by autophagy
- (2010) Eugenia Morselli et al. Autophagy
- Protein homeostasis and aging in neurodegeneration
- (2010) Peter M. Douglas et al. JOURNAL OF CELL BIOLOGY
- Can autophagy promote longevity?
- (2010) Frank Madeo et al. NATURE CELL BIOLOGY
- Asymmetrically inherited multidrug resistance transporters are recessive determinants in cellular replicative ageing
- (2010) Amr Eldakak et al. NATURE CELL BIOLOGY
- Effects of pH on aggregation kinetics of the repeat domain of a functional amyloid, Pmel17
- (2010) C. M. Pfefferkorn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sestrin as a Feedback Inhibitor of TOR That Prevents Age-Related Pathologies
- (2010) J. H. Lee et al. SCIENCE
- Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
- (2010) D. F. Egan et al. SCIENCE
- A Microarray-Based Genetic Screen for Yeast Chronological Aging Factors
- (2010) Mirela Matecic et al. PLoS Genetics
- DNA damage response and cellular senescence in tissues of aging mice
- (2009) Chunfang Wang et al. AGING CELL
- APOEpredicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging
- (2009) John C. Morris et al. ANNALS OF NEUROLOGY
- Aging: Shall We Take the High Road?
- (2009) Ikue Mori et al. CURRENT BIOLOGY
- A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging
- (2009) Matilde Murga et al. NATURE GENETICS
- Live axonal transport disruption by mutant huntingtin fragments in Drosophila motor neuron axons
- (2009) C. Sinadinos et al. NEUROBIOLOGY OF DISEASE
- Telomerase Reverse Transcriptase Delays Aging in Cancer-Resistant Mice
- (2008) Antonia Tomás-Loba et al. CELL
- Tissue-specific regulation of SIRT1 by calorie restriction
- (2008) D. Chen et al. GENES & DEVELOPMENT
- Heat shock and oxygen radicals stimulate ubiquitin-dependent degradation mainly of newly synthesized proteins
- (2008) Balasubrahmanyam Medicherla et al. JOURNAL OF CELL BIOLOGY
- Restoration of chaperone-mediated autophagy in aging liver improves cellular maintenance and hepatic function
- (2008) Cong Zhang et al. NATURE MEDICINE
- Mutations in the telomerase component NHP2 cause the premature ageing syndrome dyskeratosis congenita
- (2008) T. Vulliamy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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