标题
Regulation of cellular senescence via
the FOXO4-p53 axis
作者
关键词
-
出版物
FEBS LETTERS
Volume 592, Issue 12, Pages 2083-2097
出版商
Wiley
发表日期
2018-04-23
DOI
10.1002/1873-3468.13057
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Targeting senescent cholangiocytes and activated fibroblasts with B-cell lymphoma-extra large inhibitors ameliorates fibrosis in multidrug resistance 2 gene knockout (Mdr2−/− ) mice
- (2017) Anja Moncsek et al. HEPATOLOGY
- Targeting cellular senescence prevents age-related bone loss in mice
- (2017) Joshua N Farr et al. NATURE MEDICINE
- Tetramer formation of tumor suppressor protein p53: Structure, function, and applications
- (2016) Rui Kamada et al. BIOPOLYMERS
- Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
- (2016) Darren J. Baker et al. NATURE
- Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL
- (2016) Reut Yosef et al. Nature Communications
- Type 2 Diabetes and the Aging Pancreatic Beta Cell
- (2016) Uma Gunasekaran et al. Aging-US
- The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs
- (2015) Yi Zhu et al. AGING CELL
- Characterization of the p300 Taz2–p53 TAD2 Complex and Comparison with the p300 Taz2–p53 TAD1 Complex
- (2015) Lisa M. Miller Jenkins et al. BIOCHEMISTRY
- FoxO3a suppresses the senescence of cardiac microvascular endothelial cells by regulating the ROS-mediated cell cycle
- (2015) Xu-Feng Qi et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice
- (2015) Jianhui Chang et al. NATURE MEDICINE
- Acetylation of FoxO1 Activates Bim Expression to Induce Apoptosis in Response to Histone Deacetylase Inhibitor Depsipeptide Treatment
- (2015) Yang Yang et al. NEOPLASIA
- Cleaved high molecular weight kininogen stimulates JNK/FOXO4/MnSOD pathway for induction of endothelial progenitor cell senescence
- (2014) Xuemei Zhu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- An Essential Role for Senescent Cells in Optimal Wound Healing through Secretion of PDGF-AA
- (2014) Marco Demaria et al. DEVELOPMENTAL CELL
- The DNA-binding domain mediates both nuclear and cytosolic functions of p53
- (2014) Ariele Viacava Follis et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Stressing the cell cycle in senescence and aging
- (2013) Hollie Chandler et al. CURRENT OPINION IN CELL BIOLOGY
- The Small GTPase RALA Controls c-Jun N-terminal Kinase-mediated FOXO Activation by Regulation of a JIP1 Scaffold Complex
- (2013) Maaike C. W. van den Berg et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Redox-Dependent Control of FOXO/DAF-16 by Transportin-1
- (2013) Marrit Putker et al. MOLECULAR CELL
- Genome-wide analysis of FOXO3 mediated transcription regulation through RNA polymerase II profiling
- (2013) A. Eijkelenboom et al. Molecular Systems Biology
- Senescent Cardiac Fibroblast Is Critical for Cardiac Fibrosis after Myocardial Infarction
- (2013) Fuli Zhu et al. PLoS One
- Regulation of FOXOs and p53 by SIRT1 Modulators under Oxidative Stress
- (2013) Yusuke S. Hori et al. PLoS One
- p53 N-terminal phosphorylation: a defining layer of complex regulation
- (2012) L. M. M. Jenkins et al. CARCINOGENESIS
- The Intersection Between Aging and Cardiovascular Disease
- (2012) Brian J. North et al. CIRCULATION RESEARCH
- Competitive Binding between Dynamic p53 Transactivation Subdomains to Human MDM2 Protein
- (2012) Bing Shan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structures of KIX domain of CBP in complex with two FOXO3a transactivation domains reveal promiscuity and plasticity in coactivator recruitment
- (2012) F. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- HMGB1-Facilitated p53 DNA Binding Occurs via HMG-Box/p53 Transactivation Domain Interaction, Regulated by the Acidic Tail
- (2012) John P. Rowell et al. STRUCTURE
- Cleaved High-Molecular-Weight Kininogen Accelerates the Onset of Endothelial Progenitor Cell Senescence by Induction of Reactive Oxygen Species
- (2011) Jihong Dai et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Interaction of the p53 DNA-Binding Domain with Its N-Terminal Extension Modulates the Stability of the p53 Tetramer
- (2011) Eviatar Natan et al. JOURNAL OF MOLECULAR BIOLOGY
- Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
- (2011) Darren J. Baker et al. NATURE
- Structure of the human FOXO4-DBD–DNA complex at 1.9 Å resolution reveals new details of FOXO binding to the DNA
- (2010) Evzen Boura et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Activation of Forkhead Box O Transcription Factors by Oncogenic BRAF Promotes p21cip1-Dependent Senescence
- (2010) P. L. J. de Keizer et al. CANCER RESEARCH
- Pathways of oncogene-induced senescence in human melanocytic cells
- (2010) Rajat Bansal et al. CELL CYCLE
- The essence of senescence
- (2010) T. Kuilman et al. GENES & DEVELOPMENT
- DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion
- (2010) F. Rodier et al. JOURNAL OF CELL SCIENCE
- Diversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairs
- (2010) Malka Kitayner et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Alzheimer's Disease
- (2010) Henry W. Querfurth et al. NEW ENGLAND JOURNAL OF MEDICINE
- The relevance of protein-protein interactions for p53 function: the CPE contribution
- (2010) M. R. Fernandez-Fernandez et al. PROTEIN ENGINEERING DESIGN & SELECTION
- Two Distinct Motifs within the p53 Transactivation Domain Bind to the Taz2 Domain of p300 and Are Differentially Affected by Phosphorylation†
- (2009) Lisa M. Miller Jenkins et al. BIOCHEMISTRY
- Blinded by the Light: The Growing Complexity of p53
- (2009) Karen H. Vousden et al. CELL
- MDM2 Acts Downstream of p53 as an E3 Ligase to Promote FOXO Ubiquitination and Degradation
- (2009) Wei Fu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Sgk1 activates MDM2-dependent p53 degradation and affects cell proliferation, survival, and differentiation
- (2009) Rosario Amato et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- BrafV600E cooperates with Pten loss to induce metastatic melanoma
- (2009) David Dankort et al. NATURE GENETICS
- TP53 Mutations in Human Cancers: Origins, Consequences, and Clinical Use
- (2009) M. Olivier et al. Cold Spring Harbor Perspectives in Biology
- Akt Determines Replicative Senescence and Oxidative or Oncogenic Premature Senescence and Sensitizes Cells to Oxidative Apoptosis
- (2008) Veronique Nogueira et al. CANCER CELL
- Senescence of Activated Stellate Cells Limits Liver Fibrosis
- (2008) Valery Krizhanovsky et al. CELL
- Interaction of FOXO with β-Catenin Inhibits β-Catenin/T Cell Factor Activity
- (2008) Diana Hoogeboom et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Biochemical and Structural Characterization of an Intramolecular Interaction in FOXO3a and Its Binding with p53
- (2008) Feng Wang et al. JOURNAL OF MOLECULAR BIOLOGY
- Opposing roles for p16Ink4a and p19Arf in senescence and ageing caused by BubR1 insufficiency
- (2008) Darren J. Baker et al. NATURE CELL BIOLOGY
- Mdm2 Induces Mono-Ubiquitination of FOXO4
- (2008) Arjan B. Brenkman et al. PLoS One
- Structural Basis for DNA Recognition by FoxO1 and Its Regulation by Posttranslational Modification
- (2008) Michael M. Brent et al. STRUCTURE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now