Targeting senescent cholangiocytes and activated fibroblasts with B-cell lymphoma-extra large inhibitors ameliorates fibrosis in multidrug resistance 2 gene knockout (Mdr2−/− ) mice

Identification of a novel senolytic agent, navitoclax, targeting the Bcl-2 family of anti-apoptotic factors

(2016) Yi Zhu et al.   AGING CELL

Fibroblast activation in cancer: when seed fertilizes soil

(2016) Sanya-Eduarda Kuzet et al.   CELL AND TISSUE RESEARCH

The characteristics of activated portal fibroblasts/myofibroblasts in liver fibrosis

(2016) Daniel Karin et al.   DIFFERENTIATION

Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL

(2016) Reut Yosef et al.   Nature Communications

Platelet-Derived Growth Factor and Transforming Growth Factor β1 Regulate ARDS-Associated Lung Fibrosis Through Distinct Signaling Pathways

(2015) Xingqi Deng et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice

(2015) Jianhui Chang et al.   NATURE MEDICINE

Exploiting selective BCL-2 family inhibitors to dissect cell survival dependencies and define improved strategies for cancer therapy

(2015) Joel D. Leverson et al.   Science Translational Medicine

Cholangiocyte senescence by way of N-ras activation is a characteristic of primary sclerosing cholangitis

(2014) James H. Tabibian et al.   HEPATOLOGY

Platelet-derived Growth Factor Primes Cancer-associated Fibroblasts for Apoptosis

(2014) Sumera Rizvi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of cultured cholangiocytes isolated from livers of patients with primary sclerosing cholangitis

(2014) James H Tabibian et al.   LABORATORY INVESTIGATION

Selective anti-cancer agents as anti-aging drugs

(2013) Mikhail V Blagosklonny   CANCER BIOLOGY & THERAPY

Characterization of DNA damage-induced cellular senescence by ionizing radiation in endothelial cells

(2013) Kwang Seok Kim et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Therapeutic Effects of Deleting Cancer-Associated Fibroblasts in Cholangiocarcinoma

(2012) J. C. Mertens et al.   CANCER RESEARCH

Relative Mitochondrial Priming of Myeloblasts and Normal HSCs Determines Chemotherapeutic Success in AML

(2012) Thanh-Trang Vo et al.   CELL

The BCL-2 Family Reunion

(2010) Jerry E. Chipuk et al.   MOLECULAR CELL

Rapid in situ codetection of noncoding RNAs and proteins in cells and formalin-fixed paraffin-embedded tissue sections without protease treatment

(2010) Mariàngels de Planell-Saguer et al.   Nature Protocols

Paracrine Signaling by Platelet-Derived Growth Factor-CC Promotes Tumor Growth by Recruitment of Cancer-Associated Fibroblasts

(2008) C. Anderberg et al.   CANCER RESEARCH