p53 N-terminal phosphorylation: a defining layer of complex regulation

Structure of the human Mdmx protein bound to the p53 tumor suppressor transactivation domain

(2014) Grzegorz Popowicz et al.   CELL CYCLE

Distinct p53 Transcriptional Programs Dictate Acute DNA-Damage Responses and Tumor Suppression

(2011) Colleen A. Brady et al.   CELL

p53

(2011) Ping-yuan Wang et al.   CURRENT OPINION IN ONCOLOGY

p53 regulation by ubiquitin

(2011) Christopher L. Brooks et al.   FEBS LETTERS

Cancer Susceptibility Polymorphism of p53 at Codon 72 Affects Phosphorylation and Degradation of p53 Protein

(2011) Chikako Ozeki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Peptide-Protein Interactions Suggest That Acetylation of Lysines 381 and 382 of p53 Is Important for Positive Coactivator 4-p53 Interaction

(2011) Subrata Debnath et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Understanding the structural ensembles of a highly extended disordered protein

(2011) Gary W. Daughdrill et al.   Molecular BioSystems

Role of p53 Serine 46 in p53 Target Gene Regulation

(2011) Leonie Smeenk et al.   PLoS One

Loss of p53 Ser18 and Atm Results in Embryonic Lethality without Cooperation in Tumorigenesis

(2011) Heather L. Armata et al.   PLoS One

Protein-Protein Interactions Occur Between p53 Phosphoforms and ATM and 53BP1 at Sites of Exogenous DNA Damage

(2011) Shahnaz T. Al Rashid et al.   RADIATION RESEARCH

The impact of acetylation and deacetylation on the p53 pathway

(2011) Christopher L. Brooks et al.   Protein & Cell

Nitration of the Tumor Suppressor Protein p53 at Tyrosine 327 Promotes p53 Oligomerization and Activation

(2010) Vasily A. Yakovlev et al.   BIOCHEMISTRY

Structure of the p53 Transactivation Domain in Complex with the Nuclear Receptor Coactivator Binding Domain of CREB Binding Protein

(2010) Chul Won Lee et al.   BIOCHEMISTRY

Keeping p53 in Check: A High-Stakes Balancing Act

(2010) Shelley L. Berger   CELL

The electrostatic surface of MDM2 modulates the specificity of its interaction with phosphorylated and unphosphorylated p53 peptides

(2010) Christopher John Brown et al.   CELL CYCLE

 40p53 controls the switch from pluripotency to differentiation by regulating IGF signaling in ESCs

(2010) E. Ungewitter et al.   GENES & DEVELOPMENT

Regulation of the p53 pathway by ubiquitin and related proteins

(2010) Andreas Hock et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The role of mutant p53 in human cancer

(2010) Amanda M Goh et al.   JOURNAL OF PATHOLOGY

Requirement of the ATM/p53 Tumor Suppressor Pathway for Glucose Homeostasis

(2010) H. L. Armata et al.   MOLECULAR AND CELLULAR BIOLOGY

Endoplasmic Reticulum Stress Induces G2 Cell-Cycle Arrest via mRNA Translation of the p53 Isoform p53/47

(2010) Karima Bourougaa et al.   MOLECULAR CELL

Puma is required for p53-induced depletion of adult stem cells

(2010) Dongping Liu et al.   NATURE CELL BIOLOGY

Genotoxic exposure: novel cause of selection for a functional ΔN-p53 isoform

(2010) J P M Melis et al.   ONCOGENE

Graded enhancement of p53 binding to CREB-binding protein (CBP) by multisite phosphorylation

(2010) C. W. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mapping the physical and functional interactions between the tumor suppressors p53 and BRCA2

(2010) S. Rajagopalan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

p53 post-translational modification: deregulated in tumorigenesis

(2010) Chao Dai et al.   TRENDS IN MOLECULAR MEDICINE

Transcriptional Regulation by P53

(2010) R. Beckerman et al.   Cold Spring Harbor Perspectives in Biology

Two Distinct Motifs within the p53 Transactivation Domain Bind to the Taz2 Domain of p300 and Are Differentially Affected by Phosphorylation†

(2009) Lisa M. Miller Jenkins et al.   BIOCHEMISTRY

Mapping the Interactions of the p53 Transactivation Domain with the KIX Domain of CBP†

(2009) Chul Won Lee et al.   BIOCHEMISTRY

Limitations of Induced Folding in Molecular Recognition by Intrinsically Disordered Proteins

(2009) Eszter Hazy et al.   CHEMPHYSCHEM

Interaction between the Transactivation Domain of p53 and PC4 Exemplifies Acidic Activation Domains as Single-stranded DNA Mimics

(2009) Sridharan Rajagopalan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SMAR1 Forms a Ternary Complex with p53-MDM2 and Negatively Regulates p53-mediated Transcription

(2009) Lakshminarasimhan Pavithra et al.   JOURNAL OF MOLECULAR BIOLOGY

Transcription activity is required for p53-dependent tumor suppression

(2009) O Gaidarenko et al.   ONCOGENE

Regulation by phosphorylation of the relative affinities of the N-terminal transactivation domains of p53 for p300 domains and Mdm2

(2009) D P Teufel et al.   ONCOGENE

Cooperative regulation of p53 by modulation of ternary complex formation with CBP/p300 and HDM2

(2009) J. C. Ferreon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The rules of disorder or why disorder rules

(2009) Jörg Gsponer et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Structural Basis for p300 Taz2-p53 TAD1 Binding and Modulation by Phosphorylation

(2009) Hanqiao Feng et al.   STRUCTURE

Posttranslational Modification of p53: Cooperative Integrators of Function

(2009) D. W. Meek et al.   Cold Spring Harbor Perspectives in Biology

Genome-wide analysis of the interaction between the endosymbiotic bacterium Wolbachia and its Drosophila host

(2008) Zhiyong Xi et al.   BMC GENOMICS

Nutlin-3a Activates p53 to Both Down-regulate Inhibitor of Growth 2 and Up-regulate mir-34a, mir-34b, and mir-34c Expression, and Induce Senescence

(2008) K. Kumamoto et al.   CANCER RESEARCH

Physical and functional interactions between human mitochondrial single-stranded DNA-binding protein and tumour suppressor p53

(2008) T. S. Wong et al.   NUCLEIC ACIDS RESEARCH

Inhibition of Thr-55 phosphorylation restores p53 nuclear localization and sensitizes cancer cells to DNA damage

(2008) X. Cai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential Recognition of Phosphorylated Transactivation Domains of p53 by Different p300 Domains

(2007) Smarajit Polley et al.   JOURNAL OF MOLECULAR BIOLOGY