标题
Nutrient sensing, growth and senescence
作者
关键词
-
出版物
FEBS Journal
Volume 285, Issue 11, Pages 1948-1958
出版商
Wiley
发表日期
2018-02-06
DOI
10.1111/febs.14400
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Persistent mTORC1 signaling in cell senescence results from defects in amino acid and growth factor sensing
- (2017) Bernadette Carroll et al. JOURNAL OF CELL BIOLOGY
- The Clinical Potential of Senolytic Drugs
- (2017) James L. Kirkland et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- Transcriptional activation of RagD GTPase controls mTORC1 and promotes cancer growth
- (2017) Chiara Di Malta et al. SCIENCE
- Mitochondria in Cell Senescence: Is Mitophagy the Weakest Link?
- (2017) Viktor I. Korolchuk et al. EBioMedicine
- Age-related changes in AMPK activation: Role for AMPK phosphatases and inhibitory phosphorylation by upstream signaling pathways
- (2016) Antero Salminen et al. AGEING RESEARCH REVIEWS
- AMPK activation protects cells from oxidative stress-induced senescence via autophagic flux restoration and intracellular NAD+elevation
- (2016) Xiaojuan Han et al. AGING CELL
- Autophagy impairment with lysosomal and mitochondrial dysfunction is an important characteristic of oxidative stress-induced senescence
- (2016) Haoran Tai et al. Autophagy
- Powering senescence: The ugly side of mitochondria
- (2016) Clara Correia-Melo et al. CELL CYCLE
- Mitochondria are required for pro‐ageing features of the senescent phenotype
- (2016) Clara Correia‐Melo et al. EMBO JOURNAL
- Inpp5e suppresses polycystic kidney disease via inhibition of PI3K/Akt-dependent mTORC1 signaling
- (2016) Sandra Hakim et al. HUMAN MOLECULAR GENETICS
- Loss of Glis2/NPHP7 causes kidney epithelial cell senescence and suppresses cyst growth in the Kif3a mouse model of cystic kidney disease
- (2016) Dongmei Lu et al. KIDNEY INTERNATIONAL
- Autophagy maintains stemness by preventing senescence
- (2016) Laura García-Prat et al. NATURE
- Primary-cilium-dependent autophagy controls epithelial cell volume in response to fluid flow
- (2016) Idil Orhon et al. NATURE CELL BIOLOGY
- Lysosomal recruitment of TSC2 is a universal response to cellular stress
- (2016) Constantinos Demetriades et al. Nature Communications
- Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity
- (2016) Bernadette Carroll et al. eLife
- Dynamics of mTORC1 activation in response to amino acids
- (2016) Maria Manifava et al. eLife
- Replicatively senescent cells are arrested in G1 and G2 phases
- (2016) Zhiyong Mao et al. Aging-US
- Reciprocal regulation of cilia and autophagy via the MTOR and proteasome pathways
- (2015) Shixuan Wang et al. Autophagy
- p53-mediated autophagic regulation: A prospective strategy for cancer therapy
- (2015) Juanjuan Tang et al. CANCER LETTERS
- Senescence from G2 arrest, revisited
- (2015) Véronique Gire et al. CELL CYCLE
- Aberrant mTOR activation in senescence and aging: A mitochondrial stress response?
- (2015) Timothy Nacarelli et al. EXPERIMENTAL GERONTOLOGY
- Impaired mitophagy leads to cigarette smoke stress-induced cellular senescence: implications for chronic obstructive pulmonary disease
- (2015) Tanveer Ahmad et al. FASEB JOURNAL
- mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype
- (2015) Nicolás Herranz et al. NATURE CELL BIOLOGY
- MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation
- (2015) Remi-Martin Laberge et al. NATURE CELL BIOLOGY
- The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4
- (2015) C. Kang et al. SCIENCE
- Amino acids and autophagy: cross-talk and co-operation to control cellular homeostasis
- (2014) Bernadette Carroll et al. AMINO ACIDS
- Spatial Control of the TSC Complex Integrates Insulin and Nutrient Regulation of mTORC1 at the Lysosome
- (2014) Suchithra Menon et al. CELL
- Regulation of TORC1 in Response to Amino Acid Starvation via Lysosomal Recruitment of TSC2
- (2014) Constantinos Demetriades et al. CELL
- Ciliary abnormalities in senescent human fibroblasts impair proliferative capacity
- (2014) Loretta Breslin et al. CELL CYCLE
- Hsp90 forms a stable complex at the cilium neck for the interaction of signalling molecules in IGF-1 receptor signalling
- (2014) H. Wang et al. JOURNAL OF CELL SCIENCE
- PINK1 deficiency impairs mitochondrial homeostasis and promotes lung fibrosis
- (2014) Marta Bueno et al. JOURNAL OF CLINICAL INVESTIGATION
- Geriatric muscle stem cells switch reversible quiescence into senescence
- (2014) Pedro Sousa-Victor et al. NATURE
- Potassium channels in cell cycle and cell proliferation
- (2014) D. Urrego et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Dynamic Modelling of Pathways to Cellular Senescence Reveals Strategies for Targeted Interventions
- (2014) Piero Dalle Pezze et al. PLoS Computational Biology
- The Hallmarks of Aging
- (2013) Carlos López-Otín et al. CELL
- Autophagy and ageing: implications for age-related neurodegenerative diseases
- (2013) Bernadette Carroll et al. Essays in Biochemistry
- Functional interaction between autophagy and ciliogenesis
- (2013) Olatz Pampliega et al. NATURE
- Autophagy promotes primary ciliogenesis by removing OFD1 from centriolar satellites
- (2013) Zaiming Tang et al. NATURE
- Synthetic lethal metabolic targeting of cellular senescence in cancer therapy
- (2013) Jan R. Dörr et al. NATURE
- Autophagy-dependent senescence in response to DNA damage and chronic apoptotic stress
- (2012) Kamini Singh et al. Autophagy
- Autophagy proteins LC3B, ATG5 and ATG12 participate in quality control after mitochondrial damage and influence lifespan
- (2012) Sören Mai et al. Autophagy
- mTOR Signaling in Growth Control and Disease
- (2012) Mathieu Laplante et al. CELL
- Attenuation of TORC1 signaling delays replicative and oncogenic RAS-induced senescence
- (2012) Marina Kolesnichenko et al. CELL CYCLE
- Suppression of replicative senescence by rapamycin in rodent embryonic cells
- (2012) Tatyana V. Pospelova et al. CELL CYCLE
- CDK inhibitors (p16/p19/p21) induce senescence and autophagy in cancer-associated fibroblasts, “fueling” tumor growth via paracrine interactions, without an increase in neo-angiogenesis
- (2012) Claudia Capparelli et al. CELL CYCLE
- Autophagic activity dictates the cellular response to oncogenic RAS
- (2012) Y. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Hedgehog signalling pathway regulates autophagy
- (2012) Maria Jimenez-Sanchez et al. Nature Communications
- DNA damage response activation in mouse embryonic fibroblasts undergoing replicative senescence and following spontaneous immortalization
- (2011) Raffaella Di Micco et al. CELL CYCLE
- Pharmacologic inhibition of MEK and PI-3K converges on the mTOR/S6 pathway to decelerate cellular senescence
- (2011) Zoya N. Demidenko et al. CELL CYCLE
- Rapamycin decelerates cellular senescence
- (2011) Zoya N. Demidenko et al. CELL CYCLE
- Primary cilia and coordination of receptor tyrosine kinase (RTK) signalling
- (2011) Søren T Christensen et al. JOURNAL OF PATHOLOGY
- Hypoxia and Senescence: The Impact of Oxygenation on Tumor Suppression
- (2011) S. M. Welford et al. MOLECULAR CANCER RESEARCH
- Spatial Coupling of mTOR and Autophagy Augments Secretory Phenotypes
- (2011) M. Narita et al. SCIENCE
- The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression
- (2010) Jean-Philippe Coppé et al. Annual Review of Pathology-Mechanisms of Disease
- Growth stimulation leads to cellular senescence when the cell cycle is blocked
- (2010) Zoya N. Demidenko et al. CELL CYCLE
- SIRT1 Promotes Proliferation and Prevents Senescence Through Targeting LKB1 in Primary Porcine Aortic Endothelial Cells
- (2010) Yi Zu et al. CIRCULATION RESEARCH
- The primary cilium at a glance
- (2010) P. Satir et al. JOURNAL OF CELL SCIENCE
- Primary Cilium-Dependent and -Independent Hedgehog Signaling Inhibits p16INK4A
- (2010) Cleo L. Bishop et al. MOLECULAR CELL
- Feedback between p21 and reactive oxygen production is necessary for cell senescence
- (2010) João F Passos et al. Molecular Systems Biology
- Primary cilia regulate mTORC1 activity and cell size through Lkb1
- (2010) Christopher Boehlke et al. NATURE CELL BIOLOGY
- Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3
- (2009) Martin Gamerdinger et al. EMBO JOURNAL
- Autophagy mediates the mitotic senescence transition
- (2009) A. R.J. Young et al. GENES & DEVELOPMENT
- Growth arrest induces primary-cilium formation and sensitizes IGF-1-receptor signaling during differentiation induction of 3T3-L1 preadipocytes
- (2009) D. Zhu et al. JOURNAL OF CELL SCIENCE
- Mitochondrial Dysfunction Contributes to Oncogene-Induced Senescence
- (2009) O. Moiseeva et al. MOLECULAR AND CELLULAR BIOLOGY
- Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion
- (2009) Francis Rodier et al. NATURE CELL BIOLOGY
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