Autophagy impairment with lysosomal and mitochondrial dysfunction is an important characteristic of oxidative stress-induced senescence

AMPK activation protects cells from oxidative stress-induced senescence via autophagic flux restoration and intracellular NAD+elevation

(2016) Xiaojuan Han et al.   AGING CELL

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Mitochondria are required for pro‐ageing features of the senescent phenotype

(2016) Clara Correia‐Melo et al.   EMBO JOURNAL

Maintenance and propagation of a deleterious mitochondrial genome by the mitochondrial unfolded protein response

(2016) Yi-Fan Lin et al.   NATURE

Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila

(2014) Anne Simonsen et al.   Autophagy

Ambroxol improves lysosomal biochemistry in glucocerebrosidase mutation-linked Parkinson disease cells

(2014) Alisdair McNeill et al.   BRAIN

The Crosstalk Between Nrf2 and AMPK Signal Pathways Is Important for the Anti-Inflammatory Effect of Berberine in LPS-Stimulated Macrophages and Endotoxin-Shocked Mice

(2013) Chunfen Mo et al.   ANTIOXIDANTS & REDOX SIGNALING

Autophagy and senescence

(2013) David A. Gewirtz   Autophagy

The chemistry and biological activities of N-acetylcysteine

(2013) Yuval Samuni et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Activation of lysosomal function in the course of autophagy via mTORC1 suppression and autophagosome-lysosome fusion

(2013) Jing Zhou et al.   CELL RESEARCH

Damaged Mitochondrial DNA Replication System and the Development of Diabetic Retinopathy

(2012) Shikha Tewari et al.   ANTIOXIDANTS & REDOX SIGNALING

The Transcription Factor TFEB Links mTORC1 Signaling to Transcriptional Control of Lysosome Homeostasis

(2012) A. Roczniak-Ferguson et al.   Science Signaling

JC-1: alternative excitation wavelengths facilitate mitochondrial membrane potential cytometry

(2012) A Perelman et al.   Cell Death & Disease

Insufficient autophagy promotes bronchial epithelial cell senescence in chronic obstructive pulmonary disease

(2012) Satoko Fujii et al.   OncoImmunology

Dissecting the dynamic turnover of GFP-LC3 in the autolysosome

(2011) Hong-Min Ni et al.   Autophagy

Autophagy and Aging

(2011) David C. Rubinsztein et al.   CELL

Rapamycin decelerates cellular senescence

(2011) Zoya N. Demidenko et al.   CELL CYCLE

Uncoupling proteins and the control of mitochondrial reactive oxygen species production

(2011) Ryan J. Mailloux et al.   FREE RADICAL BIOLOGY AND MEDICINE

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

Autophagy Impairment Induces Premature Senescence in Primary Human Fibroblasts

(2011) Hyun Tae Kang et al.   PLoS One

TFEB Links Autophagy to Lysosomal Biogenesis

(2011) C. Settembre et al.   SCIENCE

Taking a “good” look at free radicals in the aging process

(2011) Siegfried Hekimi et al.   TRENDS IN CELL BIOLOGY

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

Connecting autophagy to senescence in pathophysiology

(2010) Andrew RJ Young et al.   CURRENT OPINION IN CELL BIOLOGY

Dual Role of 3-Methyladenine in Modulation of Autophagy via Different Temporal Patterns of Inhibition on Class I and III Phosphoinositide 3-Kinase

(2010) You-Tong Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Termination of autophagy and reformation of lysosomes regulated by mTOR

(2010) Li Yu et al.   NATURE

Eaten alive: a history of macroautophagy

(2010) Zhifen Yang et al.   NATURE CELL BIOLOGY

Regulation of Mammalian Autophagy in Physiology and Pathophysiology

(2010) Brinda Ravikumar et al.   PHYSIOLOGICAL REVIEWS

Long-Term IGF-I Exposure Decreases Autophagy and Cell Viability

(2010) Alessandro Bitto et al.   PLoS One

Autophagy mediates the mitotic senescence transition

(2009) A. R.J. Young et al.   GENES & DEVELOPMENT

Berberine inhibits RANKL-induced osteoclast formation and survival through suppressing the NF-κB and Akt pathways

(2007) Jin-Ping Hu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY