MECHANISMS IN ENDOCRINOLOGY: Lessons from growth hormone receptor gene-disrupted mice: are there benefits of endocrine defects?
出版年份 2018 全文链接
标题
MECHANISMS IN ENDOCRINOLOGY: Lessons from growth hormone receptor gene-disrupted mice: are there benefits of endocrine defects?
作者
关键词
-
出版物
EUROPEAN JOURNAL OF ENDOCRINOLOGY
Volume 178, Issue 5, Pages R155-R181
出版商
Bioscientifica
发表日期
2018-02-20
DOI
10.1530/eje-18-0018
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Disruption of the GH receptor gene in adult mice and in insulin sensitive tissues
- (2018) Silvana Duran-Ortiz et al. GROWTH HORMONE & IGF RESEARCH
- Androgen Receptor Regulation of Local Growth Hormone in Prostate Cancer Cells
- (2017) M. Victoria Recouvreux et al. ENDOCRINOLOGY
- Role of Growth Hormone in Breast Cancer
- (2017) Ramadevi Subramani et al. ENDOCRINOLOGY
- Spatial learning and memory in male mice with altered growth hormone action
- (2017) Amrita Basu et al. HORMONES AND BEHAVIOR
- Autocrine Human Growth Hormone Promotes Invasive and Cancer Stem Cell-Like Behavior of Hepatocellular Carcinoma Cells by STAT3 Dependent Inhibition of CLAUDIN-1 Expression
- (2017) Yi-Jun Chen et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The Role of Growth Hormone and Insulin-Like Growth Factor-I in the Liver
- (2017) Yutaka Takahashi INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Growth Hormone’s Effect on Adipose Tissue: Quality versus Quantity
- (2017) Darlene Berryman et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Growth Hormone and the Epithelial-to-Mesenchymal Transition
- (2017) Alison L Brittain et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Brain Structure and Function Associated with Younger Adults in Growth Hormone Receptor-Deficient Humans
- (2017) Kaoru Nashiro et al. JOURNAL OF NEUROSCIENCE
- Proteostasis and ageing: insights from long-lived mutant mice
- (2017) William A. Sands et al. JOURNAL OF PHYSIOLOGY-LONDON
- Feminization of Male Mouse Liver by Persistent Growth Hormone Stimulation: Activation of Sex-Biased Transcriptional Networks and Dynamic Changes in Chromatin States
- (2017) Dana Lau-Corona et al. MOLECULAR AND CELLULAR BIOLOGY
- A lysosomal switch triggers proteostasis renewal in the immortal C. elegans germ lineage
- (2017) K. Adam Bohnert et al. NATURE
- Prolonged Growth Hormone/Insulin/Insulin-like Growth Factor Nutrient Response Signaling Pathway as a Silent Killer of Stem Cells and a Culprit in Aging
- (2017) Mariusz Z. Ratajczak et al. Stem Cell Reviews and Reports
- Sex-Specific Gene Expression and Life Span Regulation
- (2017) John Tower TRENDS IN ENDOCRINOLOGY AND METABOLISM
- The Gcn4 transcription factor reduces protein synthesis capacity and extends yeast lifespan
- (2017) Nitish Mittal et al. Nature Communications
- Targeting growth hormone receptor in human melanoma cells attenuates tumor progression and epithelial mesenchymal transition via suppression of multiple oncogenic pathways
- (2017) Reetobrata Basu et al. Oncotarget
- Insulin-like growth factor-1: a possible marker for emotional and cognitive disturbances, and treatment effectiveness in major depressive disorder
- (2017) Oleg A. Levada et al. Annals of General Psychiatry
- Longevity is impacted by growth hormone action during early postnatal period
- (2017) Liou Y Sun et al. eLife
- Prolonged Growth Hormone/Insulin/Insulin-like Growth Factor Nutrient Response Signaling Pathway as a Silent Killer of Stem Cells and a Culprit in Aging
- (2017) Mariusz Z. Ratajczak et al. Stem Cell Reviews and Reports
- Growth Hormone Receptor Knockdown Sensitizes Human Melanoma Cells to Chemotherapy by Attenuating Expression of ABC Drug Efflux Pumps
- (2017) Reetobrata Basu et al. Hormones & Cancer
- The Association Between IGF-1 Levels and the Histologic Severity of Nonalcoholic Fatty Liver Disease
- (2017) Laura E Dichtel et al. Clinical and Translational Gastroenterology
- Hypothalamic growth hormone receptor (GHR) controls hepatic glucose production in nutrient-sensing leptin receptor (LepRb) expressing neurons
- (2017) Gillian Cady et al. Molecular Metabolism
- Mice overexpressing growth hormone exhibit increased skeletal muscle myostatin and MuRF1 with attenuation of muscle mass
- (2017) Leslie A. Consitt et al. Skeletal Muscle
- The GH receptor exon 3 deletion is a marker of male-specific exceptional longevity associated with increased GH sensitivity and taller stature
- (2017) Danny Ben-Avraham et al. Science Advances
- The GH/IGF-1 axis in a critical period early in life determines cellular DNA repair capacity by altering transcriptional regulation of DNA repair-related genes: implications for the developmental origins of cancer
- (2017) Andrej Podlutsky et al. GeroScience
- Growth hormone secretion is diminished and tightly controlled in humans enriched for familial longevity
- (2016) Evie van der Spoel et al. AGING CELL
- Growth hormone is increased in the lungs and enhances experimental lung metastasis of melanoma in DJ-1 KO mice
- (2016) Chia-Hung Chien et al. BMC CANCER
- Mitogenic signaling pathways in the liver of growth hormone (GH)-overexpressing mice during the growth period
- (2016) Carolina S. Martinez et al. CELL CYCLE
- The Somatotropic Axis in Human Aging: Framework for the Current State of Knowledge and Future Research
- (2016) Sofiya Milman et al. Cell Metabolism
- The Mechanistic Target of Rapamycin: The Grand ConducTOR of Metabolism and Aging
- (2016) Brian K. Kennedy et al. Cell Metabolism
- Growth Hormone Control of Hepatic Lipid Metabolism
- (2016) Zhongbo Liu et al. DIABETES
- Identification of signaling pathways associated with cancer protection in Laron syndrome
- (2016) Lena Lapkina-Gendler et al. ENDOCRINE-RELATED CANCER
- Cardiac-Specific Disruption of GH Receptor Alters Glucose Homeostasis While Maintaining Normal Cardiac Performance in Adult Male Mice
- (2016) Adam Jara et al. ENDOCRINOLOGY
- Disruption of the GH Receptor Gene in Adult Mice Increases Maximal Lifespan in Females
- (2016) Riia K. Junnila et al. ENDOCRINOLOGY
- Original Research: Metabolic alterations from early life thyroxine replacement therapy in male Ames dwarf mice are transient
- (2016) Justin Darcy et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Different Mechanisms of Longevity in Long-Lived Mouse and Caenorhabditis elegans Mutants Revealed by Statistical Analysis of Mortality Rates
- (2016) B. G. Hughes et al. GENETICS
- Despite higher body fat content, Ecuadorian subjects with Laron syndrome have less insulin resistance and lower incidence of diabetes than their relatives
- (2016) Jaime Guevara-Aguirre et al. GROWTH HORMONE & IGF RESEARCH
- The somatotropic axis and aging: Benefits of endocrine defects
- (2016) Andrzej Bartke et al. GROWTH HORMONE & IGF RESEARCH
- Cognitive and adaptive advantages of growth hormone treatment in children with Prader-Willi syndrome
- (2016) Elisabeth M. Dykens et al. JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
- Detection of Growth Hormone Deficiency in Adults with Chronic Traumatic Brain Injury
- (2016) Lisa A. Kreber et al. JOURNAL OF NEUROTRAUMA
- Compression of Morbidity Is Observed Across Cohorts with Exceptional Longevity
- (2016) Khadija Ismail et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- Enhanced Cognition and Hypoglutamatergic Signaling in a Growth Hormone Receptor Knockout Mouse Model of Successful Aging
- (2016) Kevin N. Hascup et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Healthspan and longevity can be extended by suppression of growth hormone signaling
- (2016) Andrzej Bartke MAMMALIAN GENOME
- Significantly Higher Peripheral Insulin-Like Growth Factor-1 Levels in Patients With Major Depressive Disorder or Bipolar Disorder Than in Healthy Controls
- (2016) Kun-Yu Tu et al. MEDICINE
- TIMP3 Modulates GHR Abundance and GH Sensitivity
- (2016) Yue Zhang et al. MOLECULAR ENDOCRINOLOGY
- Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma
- (2016) Jesse M. Zaretsky et al. NEW ENGLAND JOURNAL OF MEDICINE
- Growth hormone is permissive for neoplastic colon growth
- (2016) Vera Chesnokova et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Plasma insulin-like growth factor I levels are higher in depressive and anxiety disorders, but lower in antidepressant medication users
- (2016) Mariska Bot et al. PSYCHONEUROENDOCRINOLOGY
- Growth Hormone Receptor Deficiency Protects against Age-Related NLRP3 Inflammasome Activation and Immune Senescence
- (2016) Olga Spadaro et al. Cell Reports
- Risk of malignant neoplasms in acromegaly: a case–control study
- (2016) K. Wolinski et al. JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
- Brazilian adult individuals with untreated isolated GH deficiency do not have accelerated subclinical atherosclerosis
- (2016) Ursula M M Costa et al. Endocrine Connections
- Growth hormone action predicts age-related white adipose tissue dysfunction and senescent cell burden in mice
- (2016) Michael B. Stout et al. Aging-US
- Growth hormone and aging: A challenging controversy
- (2016) Andrzej Bartke Clinical Interventions in Aging
- Growth hormone modulates hypothalamic inflammation in long-lived pituitary dwarf mice
- (2015) Marianna Sadagurski et al. AGING CELL
- Interventions to Slow Aging in Humans: Are We Ready?
- (2015) Valter D. Longo et al. AGING CELL
- Gene expression defines natural changes in mammalian lifespan
- (2015) Alexey A. Fushan et al. AGING CELL
- Thyroxine modifies the effects of growth hormone in Ames dwarf mice
- (2015) Andrew Do et al. Aging-US
- Gene expression of key regulators of mitochondrial biogenesis is sex dependent in mice with growth hormone receptor deletion in liver
- (2015) Ilona Zawada et al. Aging-US
- Removal of growth hormone receptor (GHR) in muscle of male mice replicates some of the health benefits seen in global GHR−/− mice
- (2015) Edward O. List et al. Aging-US
- The somatotropic axis and longevity in mice
- (2015) H. M. Brown-Borg AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Autocrine human growth hormone stimulates the tumor initiating capacity and metastasis of estrogen receptor-negative mammary carcinoma cells
- (2015) Yi-Jun Chen et al. CANCER LETTERS
- A Comprehensive Analysis of Replicative Lifespan in 4,698 Single-Gene Deletion Strains Uncovers Conserved Mechanisms of Aging
- (2015) Mark A. McCormick et al. Cell Metabolism
- Growth Hormone Inhibits Hepatic De Novo Lipogenesis in Adult Mice
- (2015) Jose Cordoba-Chacon et al. DIABETES
- LESSONS FROM 50 YEARS OF STUDY OF LARON SYNDROME
- (2015) Zvi Laron Endocrine Practice
- Mortality in acromegaly: a 20-year follow-up study
- (2015) Elina Ritvonen et al. ENDOCRINE-RELATED CANCER
- Regulation of mTOR Activity in Snell Dwarf and GH Receptor Gene-Disrupted Mice
- (2015) Graham Dominick et al. ENDOCRINOLOGY
- Growth Hormone Receptor Antagonist Transgenic Mice Are Protected From Hyperinsulinemia and Glucose Intolerance Despite Obesity When Placed on a HF Diet
- (2015) Tianxu Yang et al. ENDOCRINOLOGY
- GH safety workshop position paper: a critical appraisal of recombinant human GH therapy in children and adults
- (2015) D B Allen et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- Growth hormone and cancer: GH production and action in glioma?
- (2015) Robert W. Lea et al. GENERAL AND COMPARATIVE ENDOCRINOLOGY
- Autocrine/paracrine roles of extrapituitary growth hormone and prolactin in health and disease: An overview
- (2015) Steve Harvey et al. GENERAL AND COMPARATIVE ENDOCRINOLOGY
- Growth Hormone Receptor Antagonist Transgenic Mice Have Increased Subcutaneous Adipose Tissue Mass, Altered Glucose Homeostasis and No Change in White Adipose Tissue Cellular Senescence
- (2015) Ross Comisford et al. GERONTOLOGY
- Brain Recovery after a Plane Crash: Treatment with Growth Hormone (GH) and Neurorehabilitation: A Case Report
- (2015) Jesús Devesa et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Autocrine/Paracrine Human Growth Hormone-stimulated MicroRNA 96-182-183 Cluster Promotes Epithelial-Mesenchymal Transition and Invasion in Breast Cancer
- (2015) Weijie Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- High Postnatal Growth Hormone Levels Are Related to Cognitive Deficits in a Group of Children Born Very Preterm
- (2015) Shannon E. Scratch et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- GH Receptor Deficiency in Ecuadorian Adults Is Associated With Obesity and Enhanced Insulin Sensitivity
- (2015) Jaime Guevara-Aguirre et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- 60 YEARS OF NEUROENDOCRINOLOGY: Acromegaly
- (2015) Cristina Capatina et al. JOURNAL OF ENDOCRINOLOGY
- Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance
- (2015) Kari R. Fischer et al. NATURE
- Growth pattern from birth to adulthood in African pygmies of known age
- (2015) Fernando V. Ramirez Rozzi et al. Nature Communications
- PD-1 pathway inhibitors: The next generation of immunotherapy for advanced melanoma
- (2015) Jason J. Luke et al. Oncotarget
- EMT, CTCs and CSCs in tumor relapse and drug-resistance
- (2015) Abhisek Mitra et al. Oncotarget
- Local Immunosuppressive Microenvironment Enhances Migration of Melanoma Cells to Lungs in DJ-1 Knockout Mice
- (2015) Chia-Hung Chien et al. PLoS One
- Effects of insulin-like growth factor 1 on glutathione S-transferases and thioredoxin in growth hormone receptor knockout mice
- (2014) Lalida Rojanathammanee et al. AGE
- Low insulin-like growth factor-1 level predicts survival in humans with exceptional longevity
- (2014) Sofiya Milman et al. AGING CELL
- Elevated GH/IGF-I promotes mammary tumors in high-fat, but not low-fat, fed mice
- (2014) Manuel D. Gahete et al. CARCINOGENESIS
- Obesity, diabetes and cancer: insight into the relationship from a cohort with growth hormone receptor deficiency
- (2014) Jaime Guevara-Aguirre et al. DIABETOLOGIA
- Senescence and apoptosis: dueling or complementary cell fates?
- (2014) B. G. Childs et al. EMBO REPORTS
- Elevated Systolic Blood Pressure in Male GH Transgenic Mice Is Age Dependent
- (2014) Adam Jara et al. ENDOCRINOLOGY
- The Absence of GH Signaling Affects the Susceptibility to High-Fat Diet-Induced Hypothalamic Inflammation in Male Mice
- (2014) Eva Baquedano et al. ENDOCRINOLOGY
- Liver-Specific GH Receptor Gene-Disrupted (LiGHRKO) Mice Have Decreased Endocrine IGF-I, Increased Local IGF-I, and Altered Body Size, Body Composition, and Adipokine Profiles
- (2014) Edward O. List et al. ENDOCRINOLOGY
- Long-term effects of growth hormone replacement therapy on liver function in adult patients with growth hormone deficiency
- (2014) Ryusaku Matsumoto et al. GROWTH HORMONE & IGF RESEARCH
- The GH-IGF1 axis and longevity. The paradigm of IGF1 deficiency
- (2014) Zvi Laron Hormones-International Journal of Endocrinology and Metabolism
- Emerging targeted therapies for melanoma treatment (Review)
- (2014) ANGELA RUSSO et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Genetic Predictors of Long-Term Response to Growth Hormone (GH) Therapy in Children With GH Deficiency and Turner Syndrome: The Influence of a SOCS2 Polymorphism
- (2014) Adriana F. Braz et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Acromegaly: An Endocrine Society Clinical Practice Guideline
- (2014) Laurence Katznelson et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Expression of Apoptosis-Related Genes in Liver-Specific Growth Hormone Receptor Gene-Disrupted Mice Is Sex Dependent
- (2014) A. Gesing et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Elevated ATF4 Function in Fibroblasts and Liver of Slow-Aging Mutant Mice
- (2014) Weiquan Li et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Growth hormone protects colorectal cancer cells from radiation by improving the ability of DNA damage repair
- (2014) XIAO-YU WU et al. Molecular Medicine Reports
- PD-1 blockade induces responses by inhibiting adaptive immune resistance
- (2014) Paul C. Tumeh et al. NATURE
- Risk of Thyroid Nodular Disease and Thyroid Cancer in Patients with Acromegaly – Meta-Analysis and Systematic Review
- (2014) Kosma Wolinski et al. PLoS One
- Lipid Profiling and Transcriptomic Analysis Reveals a Functional Interplay between Estradiol and Growth Hormone in Liver
- (2014) Leandro Fernández-Pérez et al. PLoS One
- Melanoma Vaccines
- (2014) Junko Ozao-Choy et al. SURGICAL CLINICS OF NORTH AMERICA
- Update on benefit of immunotherapy and targeted therapy in melanoma: the changing landscape
- (2014) David McDermott et al. Cancer Management and Research
- Evolution of Hepatic Steatosis to Fibrosis and Adenoma Formation in Liver-Specific Growth Hormone Receptor Knockout Mice
- (2014) Yong Fan et al. Frontiers in Endocrinology
- Growth hormone-induced insulin resistance in human subjects involves reduced pyruvate dehydrogenase activity
- (2013) B. Nellemann et al. Acta Physiologica
- The slow-aging growth hormone receptor/binding protein gene-disrupted (GHR-KO) mouse is protected from aging-resultant neuromusculoskeletal frailty
- (2013) Oge Arum et al. AGE
- Mechanisms regulating melanogenesis*
- (2013) Inês Ferreira dos Santos Videira et al. ANAIS BRASILEIROS DE DERMATOLOGIA
- Human metastatic melanoma cell lines express high levels of growth hormone receptor and respond to GH treatment
- (2013) Elahu G. Sustarsic et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Hepatocellular alterations and dysregulation of oncogenic pathways in the liver of transgenic mice overexpressing growth hormone
- (2013) Johanna G. Miquet et al. CELL CYCLE
- Expression of lymphocyte-derived growth hormone (GH) and GH-releasing hormone receptors in aging rats
- (2013) Douglas A. Weigent CELLULAR IMMUNOLOGY
- The key role of growth hormone–insulin–IGF-1 signaling in aging and cancer
- (2013) Vladimir N. Anisimov et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- Deletion of Growth Hormone Receptors in Postnatal Skeletal Muscle of Male Mice Does Not Alter Muscle Mass and Response to Pathological Injury
- (2013) Archana Vijayakumar et al. ENDOCRINOLOGY
- High insulin-like growth factor-1 in patients with bipolar I disorder: A trait marker?
- (2013) Yong-Ku Kim et al. JOURNAL OF AFFECTIVE DISORDERS
- Targeted Deletion of Growth Hormone (GH) Receptor in Macrophage Reveals Novel Osteopontin-mediated Effects of GH on Glucose Homeostasis and Insulin Sensitivity in Diet-induced Obesity
- (2013) Chunxia Lu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Idiopathic Adult Growth Hormone Deficiency
- (2013) Shlomo Melmed JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Growth Hormone Replacement Therapy in Patients with Traumatic Brain Injury
- (2013) Odile Kozlowski Moreau et al. JOURNAL OF NEUROTRAUMA
- Growth Hormone Alters the Glutathione S-Transferase and Mitochondrial Thioredoxin Systems in Long-Living Ames Dwarf Mice
- (2013) L. Rojanathammanee et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Expression of DNA Methyltransferases Is Influenced by Growth Hormone in the Long-Living Ames Dwarf Mouse In Vivo and In Vitro
- (2013) V. L. Armstrong et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- A Dwarf Mouse Model With Decreased GH/IGF-1 Activity That Does Not Experience Life-Span Extension: Potential Impact of Increased Adiposity, Leptin, and Insulin With Advancing Age
- (2013) D. E. Berryman et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Mice Producing Reduced Levels of Insulin-Like Growth Factor Type 1 Display an Increase in Maximum, but not Mean, Life Span
- (2013) A. Lorenzini et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Evaluation of growth hormone (GH) action in mice: Discovery of GH receptor antagonists and clinical indications
- (2013) John J. Kopchick et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- The Role of GH in Adipose Tissue: Lessons from Adipose-Specific GH Receptor Gene-Disrupted Mice
- (2013) Edward O. List et al. MOLECULAR ENDOCRINOLOGY
- The GH/IGF-1 axis in ageing and longevity
- (2013) Riia K. Junnila et al. Nature Reviews Endocrinology
- Growth hormone and cognitive function
- (2013) Fred Nyberg et al. Nature Reviews Endocrinology
- Ipilimumab, Vemurafenib, Dabrafenib, and Trametinib: Synergistic Competitors in the Clinical Management of BRAF Mutant Malignant Melanoma
- (2013) J. J. Luke et al. ONCOLOGIST
- The Role of PTEN in Chronic Growth Hormone-Induced Hepatic Insulin Resistance
- (2013) Yuan Gao et al. PLoS One
- Growth hormone is a cellular senescence target in pituitary and nonpituitary cells
- (2013) V. Chesnokova et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- siRNA-targeted inhibition of growth hormone receptor in human colon cancer SW480 cells
- (2013) Dong Zhou WORLD JOURNAL OF GASTROENTEROLOGY
- Growth hormone-releasing hormone disruption extends lifespan and regulates response to caloric restriction in mice
- (2013) Liou Y Sun et al. eLife
- Adult Growth Hormone Deficiency – Benefits, Side Effects, and Risks of Growth Hormone Replacement
- (2013) Mary L. Reed et al. Frontiers in Endocrinology
- Estrogens Regulate the Hepatic Effects of Growth Hormone, a Hormonal Interplay with Multiple Fates
- (2013) Leandro Fernández-Pérez et al. Frontiers in Endocrinology
- The negative effect of prolonged somatotrophic/insulin signaling on an adult bone marrow-residing population of pluripotent very small embryonic-like stem cells (VSELs)
- (2012) Magda Kucia et al. AGE
- Augmented autophagy pathways and MTOR modulation in fibroblasts from long-lived mutant mice
- (2012) Min Wang et al. Autophagy
- Autocrine human GH promotes radioresistance in mammary and endometrial carcinoma cells
- (2012) Nicola M Bougen et al. ENDOCRINE-RELATED CANCER
- Nonalcoholic fatty liver disease in adult hypopituitary patients with GH deficiency and the impact of GH replacement therapy
- (2012) H. Nishizawa et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- The role of GHR and IGF1 genes in the genetic determination of African pygmies’ short stature
- (2012) Noémie SA Becker et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Mechanisms of acquired resistance to targeted cancer therapies
- (2012) Mark R Lackner et al. Future Oncology
- Growth Hormone Receptor Blockade Inhibits Growth Hormone-Induced Chemoresistance by Restoring Cytotoxic-Induced Apoptosis in Breast Cancer Cells Independently of Estrogen Receptor Expression
- (2012) Mariella Minoia et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- GH and IGF1: Roles in Energy Metabolism of Long-Living GH Mutant Mice
- (2012) H. M. Brown-Borg et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Adipose tissue heterogeneity: Implication of depot differences in adipose tissue for obesity complications
- (2012) Mi-Jeong Lee et al. MOLECULAR ASPECTS OF MEDICINE
- Skeletal Muscle Growth Hormone Receptor Signaling Regulates Basal, but Not Fasting-Induced, Lipid Oxidation
- (2012) Archana Vijayakumar et al. PLoS One
- Targeted therapy and immunotherapy in advanced melanoma: an evolving paradigm
- (2012) Muhammad Khattak et al. Therapeutic Advances in Medical Oncology
- Targeting PD-1/PD-L1 interactions for cancer immunotherapy
- (2012) Laurence Zitvogel et al. OncoImmunology
- Metabolic effects of intra-abdominal fat in GHRKO mice
- (2011) Michal M. Masternak et al. AGING CELL
- Effect of growth hormone deficiency on brain structure, motor function and cognition
- (2011) Emma A. Webb et al. BRAIN
- Targeted Loss of GHR Signaling in Mouse Skeletal Muscle Protects Against High-Fat Diet-Induced Metabolic Deterioration
- (2011) A. Vijayakumar et al. DIABETES
- Endocrine Parameters and Phenotypes of the Growth Hormone Receptor Gene Disrupted (GHR−/−) Mouse
- (2011) Edward O. List et al. ENDOCRINE REVIEWS
- Congenital IGF1 deficiency tends to confer protection against post-natal development of malignancies
- (2011) Rachel Steuerman et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- Growth Hormone (GH)-Induced Insulin Resistance Is Rapidly Reversible: An Experimental Study in GH-Deficient Adults
- (2011) T. Krusenstjerna-Hafstrøm et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Nonalcoholic Fatty Liver Disease Is Associated with Low Circulating Levels of Insulin-Like Growth Factor-I
- (2011) Franco Arturi et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Growth hormone receptor regulates β cell hyperplasia and glucose-stimulated insulin secretion in obese mice
- (2011) Yingjie Wu et al. JOURNAL OF CLINICAL INVESTIGATION
- The Effects of Aging and Genotype on NMDA Receptor Expression in Growth Hormone Receptor Knockout (GHRKO) Mice
- (2011) K. R. Magnusson et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Expression of Key Regulators of Mitochondrial Biogenesis in Growth Hormone Receptor Knockout (GHRKO) Mice is Enhanced but is Not Further Improved by Other Potential Life-Extending Interventions
- (2011) A. Gesing et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- The growth hormone receptor polymorphism in patients with acromegaly: relationship to BMI and glucose metabolism
- (2011) Sebahat Turgut et al. Pituitary
- Cognitive function in acromegaly: description and brain volumetric correlates
- (2011) Caroline Sievers et al. Pituitary
- Growth Defect Blocks Cancer and Diabetes
- (2011) M. Leslie SCIENCE
- Growth Hormone Receptor Deficiency Is Associated with a Major Reduction in Pro-Aging Signaling, Cancer, and Diabetes in Humans
- (2011) J. Guevara-Aguirre et al. Science Translational Medicine
- Plasma proteomic profiles of bovine growth hormone transgenic mice as they age
- (2011) Juan Ding et al. TRANSGENIC RESEARCH
- Pleiotropic effects of growth hormone signaling in aging
- (2011) Andrzej Bartke TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Cancer Stem Cells and Epithelial-to-Mesenchymal Transition (EMT)-Phenotypic Cells: Are They Cousins or Twins?
- (2011) Dejuan Kong et al. Cancers
- Membrane transport proteins in human melanoma: associations with tumour aggressiveness and metastasis
- (2010) N Walsh et al. BRITISH JOURNAL OF CANCER
- Pathway Analysis of Breast Cancer Genome-Wide Association Study Highlights Three Pathways and One Canonical Signaling Cascade
- (2010) Idan Menashe et al. CANCER RESEARCH
- d3-Growth hormone receptor polymorphism in acromegaly: effects on metabolic phenotype
- (2010) Laura Montefusco et al. CLINICAL ENDOCRINOLOGY
- Early life growth hormone treatment shortens longevity and decreases cellular stress resistance in long-lived mutant mice
- (2010) Jacob A. Panici et al. FASEB JOURNAL
- Evidence of Cognitive and Neurophysiological Impairment in Patients with Untreated Naive Acromegaly
- (2010) José Leon-Carrion et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Distinct growth hormone receptor signaling modes regulate skeletal muscle development and insulin sensitivity in mice
- (2010) Mahendra D. Mavalli et al. JOURNAL OF CLINICAL INVESTIGATION
- Intrinsic Sex Differences in the Early Growth Hormone Responsiveness of Sex-Specific Genes in Mouse Liver
- (2010) Valerie Wauthier et al. MOLECULAR ENDOCRINOLOGY
- The growth hormone receptor: mechanism of activation and clinical implications
- (2010) Andrew J. Brooks et al. Nature Reviews Endocrinology
- EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer
- (2010) A Singh et al. ONCOGENE
- Human prostate cancer xenografts in lit/lit mice exhibit reduced growth and androgen-independent progression
- (2010) Kiyoshi Takahara et al. PROSTATE
- Central Obesity and Multivariable Cardiovascular Risk as Assessed by the Framingham Prediction Scores
- (2009) Satvinder S. Dhaliwal et al. AMERICAN JOURNAL OF CARDIOLOGY
- Effects of Growth Hormone on Glucose, Lipid, and Protein Metabolism in Human Subjects
- (2009) Niels Møller et al. ENDOCRINE REVIEWS
- Liver-specific Deletion of the Growth Hormone Receptor Reveals Essential Role of Growth Hormone Signaling in Hepatic Lipid Metabolism
- (2009) Yong Fan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Growth Hormone Excess Promotes Breast Cancer Chemoresistance
- (2009) Maria Chiara Zatelli et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Longevity in Untreated Congenital Growth Hormone Deficiency Due to a Homozygous Mutation in the GHRH Receptor Gene
- (2009) Manuel H. Aguiar-Oliveira et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Acromegaly pathogenesis and treatment
- (2009) Shlomo Melmed JOURNAL OF CLINICAL INVESTIGATION
- GH modulates hepatic epidermal growth factor signaling in the mouse
- (2009) Lorena González et al. JOURNAL OF ENDOCRINOLOGY
- Growth Hormone Production and Action in N1E-115 Neuroblastoma Cells
- (2009) Chelsey Grimbly et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Reduced Incidence and Delayed Occurrence of Fatal Neoplastic Diseases in Growth Hormone Receptor/Binding Protein Knockout Mice
- (2009) Y. Ikeno et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Is Altered Expression of Hepatic Insulin-Related Genes in Growth Hormone Receptor Knockout Mice Due to GH Resistance or a Difference in Biological Life Spans?
- (2009) J. A. Panici et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Two-Year Body Composition Analyses of Long-Lived GHR Null Mice
- (2009) D. E. Berryman et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Regulation of growth hormone receptors in human prostate cancer cell lines
- (2009) Maslama Bidosee et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- ABCB8 Mediates Doxorubicin Resistance in Melanoma Cells by Protecting the Mitochondrial Genome
- (2009) Aaron M. Elliott et al. MOLECULAR CANCER RESEARCH
- The shortness of Pygmies is associated with severe under-expression of the growth hormone receptor
- (2009) Mauro Bozzola et al. MOLECULAR GENETICS AND METABOLISM
- Involvement of ABC transporters in melanogenesis and the development of multidrug resistance of melanoma
- (2009) Kevin G. Chen et al. Pigment Cell & Melanoma Research
- Disruption of Growth Hormone Receptor Prevents Calorie Restriction from Improving Insulin Action and Longevity
- (2009) Michael S. Bonkowski et al. PLoS One
- Acromegaly, growth hormone and cancer risk
- (2008) Andrew G. Renehan et al. BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM
- Modulation of growth hormone receptor abundance and function: roles for the ubiquitin–proteasome system
- (2008) Stuart J. Frank et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Autocrine Human Growth Hormone Stimulates Oncogenicity of Endometrial Carcinoma Cells
- (2008) Vijay Pandey et al. ENDOCRINOLOGY
- Autocrine Human Growth Hormone Promotes Tumor Angiogenesis in Mammary Carcinoma
- (2008) Severine E. Brunet-Dunand et al. ENDOCRINOLOGY
- Cognition in the adult with childhood-onset GH deficiency
- (2008) I Caroline van Nieuwpoort et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- Long-living growth hormone receptor knockout mice: Potential mechanisms of altered stress resistance
- (2008) Holly M. Brown-Borg et al. EXPERIMENTAL GERONTOLOGY
- Effects of growth hormone overexpression vs. growth hormone receptor gene disruption on mouse hindlimb muscle fiber type composition
- (2008) Mark D. Schuenke et al. GROWTH HORMONE & IGF RESEARCH
- Nonalcoholic fatty liver in patients with Laron syndrome and GH gene deletion – Preliminary report
- (2008) Zvi Laron et al. GROWTH HORMONE & IGF RESEARCH
- Effect of circulating growth hormone on muscle IGF-I protein concentration in female mice with growth hormone receptor gene disruption
- (2008) William J. Kraemer et al. GROWTH HORMONE & IGF RESEARCH
- Ten Years of Growth Hormone (GH) Replacement Normalizes Muscle Strength in GH-Deficient Adults
- (2008) Galina Götherström et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- The Contribution of Growth Hormone to Mammary Neoplasia
- (2008) Jo K. Perry et al. JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA
- The obesity of patients with Laron Syndrome is not associated with excessive nutritional intake
- (2008) Shira Ginsberg et al. Obesity Research & Clinical Practice
- Functionally significant insulin-like growth factor I receptor mutations in centenarians
- (2008) Y. Suh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Risk of colorectal neoplasm in patients with acromegaly: A meta-analysis
- (2008) Theodoros Rokkas et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Hippocampus of Ames dwarf mice is resistant to β-amyloid-induced tau hyperphosphorylation and changes in apoptosis-regulatory protein levels
- (2007) Matthew Schrag et al. HIPPOCAMPUS
- Mortality in Acromegaly: A Metaanalysis
- (2007) O. M. Dekkers et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search