Xenobiotica-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin models
出版年份 2018 全文链接
标题
Xenobiotica-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin models
作者
关键词
Cutaneous xenobiotic metabolism, Species differences, Human skin models, Rat, Mouse, Pig, Guinea pig
出版物
ARCHIVES OF TOXICOLOGY
Volume -, Issue -, Pages -
出版商
Springer Nature
发表日期
2018-06-18
DOI
10.1007/s00204-018-2232-x
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Characterization of xenobiotic metabolizing enzymes of a reconstructed human epidermal model from adult hair follicles
- (2017) Daniel Bacqueville et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Dermal Xenobiotic Metabolism: A Comparison between Native Human Skin, Four in vitro Skin Test Systems and a Liver System
- (2017) Christian Wiegand et al. SKIN PHARMACOLOGY AND PHYSIOLOGY
- Balancing intestinal and systemic inflammation through cell type-specific expression of the aryl hydrocarbon receptor repressor
- (2016) Olga Brandstätter et al. Scientific Reports
- Evidence for New Light-Independent Pathways for Generation of the Endogenous Aryl Hydrocarbon Receptor Agonist FICZ
- (2015) Anna Smirnova et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Xenobiotic metabolizing enzymes in human skin and SkinEthic reconstructed human skin models
- (2015) Joan Eilstein et al. EXPERIMENTAL DERMATOLOGY
- Skin response to a carcinogen involves the xenobiotic receptor pregnane X receptor
- (2015) Andreas Elentner et al. EXPERIMENTAL DERMATOLOGY
- Extrapolation of systemic bioavailability assessing skin absorption and epidermal and hepatic metabolism of aromatic amine hair dyes in vitro
- (2015) John Manwaring et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Glutathione metabolism in the HaCaT cell line as a model for the detoxification of the model sensitisers 2,4-dinitrohalobenzenes in human skin
- (2015) Sandrine Jacquoilleot et al. TOXICOLOGY LETTERS
- The Aryl Hydrocarbon Receptor: Multitasking in the Immune System
- (2014) Brigitta Stockinger et al. Annual Review of Immunology
- Cytochromes P450 and Skin Cancer: Role of Local Endocrine Pathways
- (2014) Andrzej Slominski et al. Anti-Cancer Agents in Medicinal Chemistry
- Comparison of xenobiotic metabolizing enzyme activities in ex vivo human skin and reconstructed human skin models from SkinEthic
- (2014) Joan Eilstein et al. ARCHIVES OF TOXICOLOGY
- Xenobiotic-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin models
- (2014) F. Oesch et al. ARCHIVES OF TOXICOLOGY
- Modulation of aryl hydrocarbon receptor (AHR)-dependent signaling by peroxisome proliferator-activated receptor β/δ (PPARβ/δ) in keratinocytes
- (2014) Michael G. Borland et al. CARCINOGENESIS
- Extrahepatic metabolism at the body's internal–external interfaces
- (2014) Ursula Gundert-Remy et al. DRUG METABOLISM REVIEWS
- Insights on the human microbiome and its xenobiotic metabolism: what is known about its effects on human physiology?
- (2014) Tewes Tralau et al. Expert Opinion on Drug Metabolism & Toxicology
- Effect of Skin Metabolism on Dermal Delivery of Testosterone: Qualitative Assessment using a New Short-Term Skin Model
- (2014) C. Jacques et al. SKIN PHARMACOLOGY AND PHYSIOLOGY
- LuSens: A keratinocyte based ARE reporter gene assay for use in integrated testing strategies for skin sensitization hazard identification
- (2014) Tzutzuy Ramirez et al. TOXICOLOGY IN VITRO
- Characterization of a human epidermis model reconstructed from hair follicle keratinocytes and comparison with two commercially models and native skin
- (2014) B. Guiraud et al. INTERNATIONAL JOURNAL OF COSMETIC SCIENCE
- Xenobiotic metabolizing enzyme activities in cells used for testing skin sensitization in vitro
- (2013) E. Fabian et al. ARCHIVES OF TOXICOLOGY
- Nevirapine Bioactivation and Covalent Binding in the Skin
- (2013) Amy M. Sharma et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Identification of Danger Signals in Nevirapine-Induced Skin Rash
- (2013) Xiaochu Zhang et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Reduction of Aromatic and Heterocyclic Aromatic N-Hydroxylamines by Human Cytochrome P450 2S1
- (2013) Kai Wang et al. CHEMICAL RESEARCH IN TOXICOLOGY
- 12-OH-Nevirapine Sulfate, Formed in the Skin, Is Responsible for Nevirapine-Induced Skin Rash
- (2013) Amy M. Sharma et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Regulation of the cytosolic sulfotransferases by nuclear receptors
- (2013) Melissa Runge-Morris et al. DRUG METABOLISM REVIEWS
- Degradation of benzo[a]pyrene by bacterial isolates from human skin
- (2013) Juliane Sowada et al. FEMS MICROBIOLOGY ECOLOGY
- Skin tumorigenic potential of benzanthrone: Prevention by ascorbic acid
- (2013) Neelam Dwivedi et al. FOOD AND CHEMICAL TOXICOLOGY
- N-acetylation of three aromatic amine hair dye precursor molecules eliminates their genotoxic potential
- (2013) Andreas Zeller et al. MUTAGENESIS
- The Role of Human Carboxylesterases in Drug Metabolism: Have We Overlooked Their Importance?
- (2013) S. Casey Laizure et al. PHARMACOTHERAPY
- Life on Human Surfaces: Skin Metagenomics
- (2013) Alban Mathieu et al. PLoS One
- Use of Human In Vitro Skin Models for Accurate and Ethical Risk Assessment: Metabolic Considerations
- (2013) Nicola J. Hewitt et al. TOXICOLOGICAL SCIENCES
- Hypoxia perturbs aryl hydrocarbon receptor signaling and CYP1A1 expression induced by PCB 126 in human skin and liver-derived cell lines
- (2013) Sabine U. Vorrink et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Skin permeation and metabolism of di(2-ethylhexyl) phthalate (DEHP)
- (2013) N.B. Hopf et al. TOXICOLOGY LETTERS
- Involvement of Carboxylesterase in Hydrolysis of Propranolol Prodrug during Permeation across Rat Skin
- (2013) Teruko Imai et al. Pharmaceutics
- Effect of phytochemicals on phase II enzyme expression in infant human primary skin fibroblast cells
- (2012) Eliz Warwick et al. BRITISH JOURNAL OF NUTRITION
- Esterase activity in excised and reconstructed human skin – Biotransformation of prednicarbate and the model dye fluorescein diacetate
- (2012) Franzisca Marie Bätz et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Xenobiotic metabolism capacities of human skin in comparison with a 3D-epidermis model and keratinocyte-based cell culture as in vitro alternatives for chemical testing: phase II enzymes
- (2012) Christine Götz et al. EXPERIMENTAL DERMATOLOGY
- Xenobiotic metabolism capacities of human skin in comparison with a 3D epidermis model and keratinocyte-based cell culture as in vitro alternatives for chemical testing: activating enzymes (Phase I)
- (2012) Christine Götz et al. EXPERIMENTAL DERMATOLOGY
- Relevance of xenobiotic enzymes in human skinin vitromodels to activate pro-sensitizers
- (2012) Christine Jäckh et al. Journal of Immunotoxicology
- EH3 (ABHD9): the first member of a new epoxide hydrolase family with high activity for fatty acid epoxides
- (2012) Martina Decker et al. JOURNAL OF LIPID RESEARCH
- Elucidation of Xenobiotic Metabolism Pathways in Human Skin and Human Skin Models by Proteomic Profiling
- (2012) Sven van Eijl et al. PLoS One
- Langerhans Cells Facilitate Epithelial DNA Damage and Squamous Cell Carcinoma
- (2012) B. G. Modi et al. SCIENCE
- Morphine Metabolism in Human Skin Microsomes
- (2012) S. Heilmann et al. SKIN PHARMACOLOGY AND PHYSIOLOGY
- Metabolically Competent Human Skin Models: Activation and Genotoxicity of Benzo[a]pyrene
- (2012) Joep Brinkmann et al. TOXICOLOGICAL SCIENCES
- The use of THP-1 cells as a model for mimicking the function and regulation of monocytes and macrophages in the vasculature
- (2011) Zhenyu Qin ATHEROSCLEROSIS
- Metabolic Changes in Skin Caused by Scd1 Deficiency: A Focus on Retinol Metabolism
- (2011) Matthew T. Flowers et al. PLoS One
- Characterization of enzyme activities of Cytochrome P450 enzymes, Flavin-dependent monooxygenases, N-acetyltransferases and UDP-glucuronyltransferases in human reconstructed epidermis and full-thickness skin models
- (2011) Christine Jäckh et al. TOXICOLOGY IN VITRO
- Intralaboratory validation of four in vitro assays for the prediction of the skin sensitizing potential of chemicals
- (2011) Caroline Bauch et al. TOXICOLOGY IN VITRO
- Case report of extensive metabolism by aldehyde oxidase in humans: Pharmacokinetics and metabolite profile of FK3453 in rats, dogs, and humans
- (2011) Takafumi Akabane et al. XENOBIOTICA
- Exposure to naphthalene induces naphthyl-keratin adducts in human epidermisin vitroandin vivo
- (2010) Juei-Chuan C. Kang-Sickel et al. BIOMARKERS
- Diphenylthiourea, a Common Rubber Chemical, Is Bioactivated to Potent Skin Sensitizers
- (2010) Kristin Samuelsson et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Viable skin efficiently absorbs and metabolizes bisphenol A
- (2010) Daniel Zalko et al. CHEMOSPHERE
- In silico and in vitro pharmacogenetics: aldehyde oxidase rapidly metabolizes a p38 kinase inhibitor
- (2010) X Zhang et al. PHARMACOGENOMICS JOURNAL
- Expression and Induction of Cytochrome P450 Isoenzymes in Human Skin Equivalents
- (2010) M.M. Neis et al. SKIN PHARMACOLOGY AND PHYSIOLOGY
- Exposure of human skin to benzo[a]pyrene: Role of CYP1A1 and aryl hydrocarbon receptor in oxidative stress generation
- (2010) C. Costa et al. TOXICOLOGY
- Xenobiotic metabolism gene expression in the EpiDerm™ in vitro 3D human epidermis model compared to human skin
- (2010) T. Hu et al. TOXICOLOGY IN VITRO
- Percutaneous absorption and metabolism of [14C]-ethoxycoumarin in a pig ear skin model
- (2010) Carine Jacques et al. TOXICOLOGY IN VITRO
- A potential in vitro epidermal equivalent assay to determine sensitizer potency
- (2010) Guilherme G. dos Santos et al. TOXICOLOGY IN VITRO
- Disposition and biotransformation of 14C-Benzo(a)pyrene in a pig ear skin model: Ex vivo and in vitro approaches
- (2010) Carine Jacques et al. TOXICOLOGY LETTERS
- 20-Hydroxylation is the CYP-dependent and retinoid-inducible leukotriene B4 inactivation pathway in human and mouse skin cells
- (2009) Liping Du et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Drug skin metabolites and allergic drug reactions
- (2009) Hans F Merk Current Opinion in Allergy and Clinical Immunology
- Cross-Species Comparison of the Metabolism and Excretion of Zoniporide: Contribution of Aldehyde Oxidase to Interspecies Differences
- (2009) D. Dalvie et al. DRUG METABOLISM AND DISPOSITION
- Sulfation of O-Demethyl Apixaban: Enzyme Identification and Species Comparison
- (2009) L. Wang et al. DRUG METABOLISM AND DISPOSITION
- Molecular modeling of human cytochrome P450 2W1 and its interactions with substrates
- (2009) Weihua Li et al. JOURNAL OF MOLECULAR GRAPHICS & MODELLING
- Expression profiles of phases 1 and 2 metabolizing enzymes in human skin and the reconstructed skin models Episkin™ and full thickness model from Episkin™
- (2009) Van Luu-The et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Assessment of human epidermal model LabCyte EPI-MODEL for in vitro skin irritation testing according to European Centre for the Validation of Alternative Methods (ECVAM)-validated protocol
- (2009) Masakazu Katoh et al. JOURNAL OF TOXICOLOGICAL SCIENCES
- Fatty Acid Hydroperoxides Support Cytochrome P450 2S1-Mediated Bioactivation of Benzo[a]pyrene-7,8-dihydrodiol
- (2009) P. H. Bui et al. MOLECULAR PHARMACOLOGY
- Functional Characterization of Human Cytochrome P450 2S1 Using a Synthetic Gene-Expressed Protein in Escherichia coli
- (2009) P. H. Bui et al. MOLECULAR PHARMACOLOGY
- Evaluation of cytochrome P450 1 (CYP1) and N-acetyltransferase 1 (NAT1) activities in HaCaT cells: Implications for the development of in vitro techniques for predictive testing of contact sensitizers
- (2009) Jutta Bonifas et al. TOXICOLOGY IN VITRO
- Dermal penetration and metabolism of p-aminophenol and p-phenylenediamine: Application of the EpiDerm™ human reconstructed epidermis model
- (2009) Ting Hu et al. TOXICOLOGY LETTERS
- Different patterns of 5α-reductase expression, cellular distribution, and testosterone metabolism in human follicular dermal papilla cells
- (2008) Shicheng Liu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Mouse N-acetyltransferase type 2, the homologue of human N-acetyltransferase type 1
- (2008) Akane Kawamura et al. BIOCHEMICAL PHARMACOLOGY
- Expression and Function of Cytochrome P450-Dependent Enzymes in Human Skin Cells
- (2008) J. Baron et al. CURRENT MEDICINAL CHEMISTRY
- Skin permeation and ex vivo skin metabolism of O-acyl haloperidol ester prodrugs
- (2008) Andrew P. Morris et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Skin metabolism of aminophenols: Human keratinocytes as a suitable in vitro model to qualitatively predict the dermal transformation of 4-amino-2-hydroxytoluene in vivo
- (2008) C. Goebel et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search