Insights on the human microbiome and its xenobiotic metabolism: what is known about its effects on human physiology?

Serotonin, tryptophan metabolism and the brain-gut-microbiome axis

(2015) S.M. O’Mahony et al.   BEHAVIOURAL BRAIN RESEARCH

Gut Microbial Metabolism Drives Transformation of Msh2-Deficient Colon Epithelial Cells

(2014) Antoaneta Belcheva et al.   CELL

Understanding the Apothecaries Within: The Necessity of a Systematic Approach for Defining the Chemical Output of the Human Microbiome

(2014) Kirk Beebe et al.   CTS-Clinical and Translational Science

Glucose metabolism: Focus on gut microbiota, the endocannabinoid system and beyond

(2014) P.D. Cani et al.   DIABETES & METABOLISM

Pyrosequencing reveals transient cystic fibrosis lung microbiome changes with intravenous antibiotics

(2014) D. J. Smith et al.   EUROPEAN RESPIRATORY JOURNAL

Role of the Microbiome in Energy Regulation and Metabolism

(2014) Max Nieuwdorp et al.   GASTROENTEROLOGY

Minireview: Gut Microbiota: The Neglected Endocrine Organ

(2014) Gerard Clarke et al.   MOLECULAR ENDOCRINOLOGY

Pharmacomicrobiomics: The Impact of Human Microbiome Variations on Systems Pharmacology and Personalized Therapeutics

(2014) Marwa ElRakaiby et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Programmable bacteria detect and record an environmental signal in the mammalian gut

(2014) Jonathan W. Kotula et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional genomics of Lactobacillus casei establishment in the gut

(2014) H. Licandro-Seraut et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gut microbiota and GLP-1

(2014) Amandine Everard et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Development of a targeted method for twenty-three metabolites related to polyphenol gut microbial metabolism in biological samples, using SPE and UHPLC–ESI-MS/MS

(2014) Mattia Gasperotti et al.   TALANTA

Metatranscriptomics of the Human Oral Microbiome during Health and Disease

(2014) P. Jorth et al.   mBio

Fecal microbial metabolism of polyphenols and its effects on human gut microbiota

(2013) Shanthi G. Parkar et al.   ANAEROBE

Function of the microbiota

(2013) Mirjana Rajilić-Stojanović   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental Disorders

(2013) Elaine Y. Hsiao et al.   CELL

Xenobiotics Shape the Physiology and Gene Expression of the Active Human Gut Microbiome

(2013) Corinne Ferrier Maurice et al.   CELL

Fusobacterium nucleatum Potentiates Intestinal Tumorigenesis and Modulates the Tumor-Immune Microenvironment

(2013) Aleksandar D. Kostic et al.   Cell Host & Microbe

Fusobacterium nucleatum Promotes Colorectal Carcinogenesis by Modulating E-Cadherin/β-Catenin Signaling via its FadA Adhesin

(2013) Mara Roxana Rubinstein et al.   Cell Host & Microbe

The Human Gut Microbiome and Body Metabolism: Implications for Obesity and Diabetes

(2013) S. Devaraj et al.   CLINICAL CHEMISTRY

Cometabolism of Microbes and Host: Implications for Drug Metabolism and Drug-Induced Toxicity

(2013) H Li et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The human microbiome is a source of therapeutic drug targets

(2013) Bret D Wallace et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Omics approaches to study host–microbiota interactions

(2013) Peter van Baarlen et al.   CURRENT OPINION IN MICROBIOLOGY

Human intestinal metagenomics: state of the art and future

(2013) Hervé M Blottière et al.   CURRENT OPINION IN MICROBIOLOGY

Gut microbiota, enteroendocrine functions and metabolism

(2013) Patrice D Cani et al.   CURRENT OPINION IN PHARMACOLOGY

Nuclear receptors in bile acid metabolism

(2013) Tiangang Li et al.   DRUG METABOLISM REVIEWS

Bacterial landscape of human skin: seeing the forest for the trees

(2013) Oleg A. Alexeyev   EXPERIMENTAL DERMATOLOGY

The evolution of our understanding of endo-xenobiotic crosstalk and cytochrome P450 regulation and the therapeutic implications

(2013) Tewes Tralau et al.   Expert Opinion on Drug Metabolism & Toxicology

Gut microbiota-based translational biomarkers to prevent metabolic syndrome via nutritional modulation

(2013) Shuiming Xiao et al.   FEMS MICROBIOLOGY ECOLOGY

Degradation of benzo[a]pyrene by bacterial isolates from human skin

(2013) Juliane Sowada et al.   FEMS MICROBIOLOGY ECOLOGY

Muscle wasting: The gut microbiota as a new therapeutic target?

(2013) Laure B. Bindels et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Impact of Polyphenols and Polyphenol-Rich Dietary Sources on Gut Microbiota Composition

(2013) Usune Etxeberria et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Impact of oral vancomycin on gut microbiota, bile acid metabolism, and insulin sensitivity

(2013) Anne Vrieze et al.   JOURNAL OF HEPATOLOGY

Three-stage continuous culture system with a self-generated anaerobia to study the regionalized metabolism of the human gut microbiota

(2013) David Feria-Gervasio et al.   JOURNAL OF MICROBIOLOGICAL METHODS

The Gut Microbiome, Kidney Disease, and Targeted Interventions

(2013) A. Ramezani et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Microbiota-liberated host sugars facilitate post-antibiotic expansion of enteric pathogens

(2013) Katharine M. Ng et al.   NATURE

Life on Human Surfaces: Skin Metagenomics

(2013) Alban Mathieu et al.   PLoS One

Analyses of the Stability and Core Taxonomic Memberships of the Human Microbiome

(2013) Kelvin Li et al.   PLoS One

Host-compound foraging by intestinal microbiota revealed by single-cell stable isotope probing

(2013) D. Berry et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Predicting and Manipulating Cardiac Drug Inactivation by the Human Gut Bacterium Eggerthella lenta

(2013) H. J. Haiser et al.   SCIENCE

The Intestinal Microbiota Modulates the Anticancer Immune Effects of Cyclophosphamide

(2013) S. Viaud et al.   SCIENCE

Sex Differences in the Gut Microbiome Drive Hormone-Dependent Regulation of Autoimmunity

(2013) J. G. M. Markle et al.   SCIENCE

Conserved Shifts in the Gut Microbiota Due to Gastric Bypass Reduce Host Weight and Adiposity

(2013) A. P. Liou et al.   Science Translational Medicine

The Gut Microbiome Modulates Colon Tumorigenesis

(2013) J. P. Zackular et al.   mBio

Bacterial skin commensals and their role as host guardians

(2013) G.J.M. Christensen et al.   Beneficial Microbes

Microbial Ecology of the Skin in the Era of Metagenomics and Molecular Microbiology

(2013) G. D. Hannigan et al.   Cold Spring Harbor Perspectives in Medicine

Hot topics in gut microbiota

(2013) Joël Doré et al.   United European Gastroenterology Journal

Bioremediation and Tolerance of Humans to Heavy Metals through Microbial Processes: a Potential Role for Probiotics?

(2012) Marc Monachese et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Protective Effects of Lactobacillus plantarum CCFM8610 against Acute Cadmium Toxicity in Mice

(2012) Qixiao Zhai et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

A meta-metabolome network of carbohydrate metabolism: Interactions between gut microbiota and host

(2012) Maziya Ibrahim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Data mining the human gut microbiota for therapeutic targets

(2012) M. Collison et al.   BRIEFINGS IN BIOINFORMATICS

Host Remodeling of the Gut Microbiome and Metabolic Changes during Pregnancy

(2012) Omry Koren et al.   CELL

The Impact of the Gut Microbiota on Human Health: An Integrative View

(2012) Jose C. Clemente et al.   CELL

Gut Microbiota Composition and Activity in Relation to Host Metabolic Phenotype and Disease Risk

(2012) Elaine Holmes et al.   Cell Metabolism

Crosstalk between the gut microbiota and the endocannabinoid system: impact on the gut barrier function and the adipose tissue

(2012) P.D. Cani   CLINICAL MICROBIOLOGY AND INFECTION

The chemical interactome space between the human host and the genetically defined gut metabotypes

(2012) Ulrik Plesner Jacobsen et al.   ISME Journal

Metabolic Influence of Acute Cyadox Exposure on Kunming Mice

(2012) Chongyang Huang et al.   JOURNAL OF PROTEOME RESEARCH

Temporal and spatial interplay of microbiota and intestinal mucosa drive establishment of immune homeostasis in conventionalized mice

(2012) Sahar El Aidy et al.   Mucosal Immunology

The role of the gut microbiota in nutrition and health

(2012) Harry J. Flint et al.   Nature Reviews Gastroenterology & Hepatology

Bacteriocins — a viable alternative to antibiotics?

(2012) Paul D. Cotter et al.   NATURE REVIEWS MICROBIOLOGY

The human gastrointestinal microbiota—An unexplored frontier for pharmaceutical discovery

(2012) Guus Roeselers et al.   PHARMACOLOGICAL RESEARCH

Developing a metagenomic view of xenobiotic metabolism

(2012) Henry J. Haiser et al.   PHARMACOLOGICAL RESEARCH

Complex Carbohydrate Utilization by the Healthy Human Microbiome

(2012) Brandi L. Cantarel et al.   PLoS One

Analyses of the Microbial Diversity across the Human Microbiome

(2012) Kelvin Li et al.   PLoS One

Butyrate and Propionate Protect against Diet-Induced Obesity and Regulate Gut Hormones via Free Fatty Acid Receptor 3-Independent Mechanisms

(2012) Hua V. Lin et al.   PLoS One

The Effect of Selected Synbiotics on Microbial Composition and Short-Chain Fatty Acid Production in a Model System of the Human Colon

(2012) Gabriella C. van Zanten et al.   PLoS One

Microbial conversion of choline to trimethylamine requires a glycyl radical enzyme

(2012) S. Craciun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Compartmentalized Control of Skin Immunity by Resident Commensals

(2012) S. Naik et al.   SCIENCE

Intestinal Inflammation Targets Cancer-Inducing Activity of the Microbiota

(2012) J. C. Arthur et al.   SCIENCE

Therapeutic Modulation of Microbiota-Host Metabolic Interactions

(2012) E. Holmes et al.   Science Translational Medicine

The human gut microbiome: current knowledge, challenges, and future directions

(2012) Maneesh Dave et al.   Translational Research

Microbial Co-occurrence Relationships in the Human Microbiome

(2012) Karoline Faust et al.   PLoS Computational Biology

Lactic acid bacteria contribution to gut microbiota complexity: lights and shadows

(2012) Enrica Pessione   Frontiers in Cellular and Infection Microbiology

Immunology and probiotic impact of the newborn and young children intestinal microflora

(2011) Eugenia Bezirtzoglou et al.   ANAEROBE

Microbiota profile in feces of breast- and formula-fed newborns by using fluorescence in situ hybridization (FISH)

(2011) Eugenia Bezirtzoglou et al.   ANAEROBE

The potter’s wheel: the host’s role in sculpting its microbiota

(2011) Charles L. Bevins et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The bacterial chemical repertoire mediates metabolic exchange within gut microbiomes

(2011) Christopher M Rath et al.   CURRENT OPINION IN MICROBIOLOGY

Skin microbiota: Microbial community structure and its potential association with health and disease

(2011) Mariana Rosenthal et al.   INFECTION GENETICS AND EVOLUTION

Diversity of the Human Skin Microbiome Early in Life

(2011) Kimberly A. Capone et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Microbial Symbiosis with the Innate Immune Defense System of the Skin

(2011) Richard L. Gallo et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Ecology drives a global network of gene exchange connecting the human microbiome

(2011) Chris S. Smillie et al.   NATURE

Enterotypes of the human gut microbiome

(2011) Manimozhiyan Arumugam et al.   NATURE

Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve

(2011) J. A. Bravo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Normal gut microbiota modulates brain development and behavior

(2011) R. D. Heijtz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Skin microbiome: genomics-based insights into the diversity and role of skin microbes

(2011) Heidi H. Kong   TRENDS IN MOLECULAR MEDICINE

Colonization-Induced Host-Gut Microbial Metabolic Interaction

(2011) S. P. Claus et al.   mBio

Effects of the enteric bacterial metabolic product propionic acid on object-directed behavior, social behavior, cognition, and neuroinflammation in adolescent rats: Relevance to autism spectrum disorder

(2010) Derrick F. MacFabe et al.   BEHAVIOURAL BRAIN RESEARCH

Endocrine Diseases and the Liver

(2010) Anurag Maheshwari et al.   Clinics in Liver Disease

Endocannabinoid biosynthesis and inactivation, from simple to complex

(2010) Giulio G. Muccioli   DRUG DISCOVERY TODAY

Predictive tools for the evaluation of microbial effects on drugs during gastrointestinal passage

(2010) Ines A Pieper et al.   Expert Opinion on Drug Metabolism & Toxicology

Drug metabolome of the Simvastatin formed by human intestinal microbiota in vitro

(2010) Anna-Marja Aura et al.   Molecular BioSystems

The endocannabinoid system links gut microbiota to adipogenesis

(2010) Giulio G Muccioli et al.   Molecular Systems Biology

A human gut microbial gene catalogue established by metagenomic sequencing

(2010) Junjie Qin et al.   NATURE

Reduced anxiety-like behavior and central neurochemical change in germ-free mice

(2010) K. M. Neufeld et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Succession of microbial consortia in the developing infant gut microbiome

(2010) J. E. Koenig et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns

(2010) M. G. Dominguez-Bello et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alleviating Cancer Drug Toxicity by Inhibiting a Bacterial Enzyme

(2010) B. D. Wallace et al.   SCIENCE

Obesity and the human microbiome

(2009) Ruth E Ley   CURRENT OPINION IN GASTROENTEROLOGY

Impact of Gut Microbiota on Intestinal and Hepatic Levels of Phase 2 Xenobiotic-Metabolizing Enzymes in the Rat

(2009) W. Meinl et al.   DRUG METABOLISM AND DISPOSITION

The NIH Human Microbiome Project

(2009) et al.   GENOME RESEARCH

An Internal Reaction Chamber in Dimethylglycine Oxidase Provides Efficient Protection from Exposure to Toxic Formaldehyde

(2009) Tewes Tralau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metabolism of azo dyes by human skin microbiota

(2009) R. L. Stingley et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Commensal bacteria regulate Toll-like receptor 3–dependent inflammation after skin injury

(2009) Yuping Lai et al.   NATURE MEDICINE

The University of Minnesota Biocatalysis/Biodegradation Database: improving public access

(2009) Junfeng Gao et al.   NUCLEIC ACIDS RESEARCH

Choline: an essential nutrient for public health

(2009) Steven H Zeisel et al.   NUTRITION REVIEWS

Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites

(2009) W. R. Wikoff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism

(2009) T. A. Clayton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Topographical and Temporal Diversity of the Human Skin Microbiome

(2009) E. A. Grice et al.   SCIENCE

Bacterial Community Variation in Human Body Habitats Across Space and Time

(2009) E. K. Costello et al.   SCIENCE

Role of Intestinal Microbiota in Transformation of Bismuth and Other Metals and Metalloids into Volatile Methyl and Hydride Derivatives in Humans and Mice

(2008) K. Michalke et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

A diversity profile of the human skin microbiota

(2008) E. A. Grice et al.   GENOME RESEARCH

The gastrointestinal microbiota as a site for the biotransformation of drugs

(2008) Tiago Sousa et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Gut instincts: Explorations in intestinal physiology and drug delivery

(2008) Emma L. McConnell et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Top-down systems biology integration of conditional prebiotic modulated transgenomic interactions in a humanized microbiome mouse model

(2008) Francois-Pierre J Martin et al.   Molecular Systems Biology

The influence of sex, handedness, and washing on the diversity of hand surface bacteria

(2008) N. Fierer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41

(2008) B. S. Samuel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Symbiotic gut microbes modulate human metabolic phenotypes

(2008) M. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA