N-Heterocyclic Carbene Catalysis via Azolium Dienolates: An Efficient Strategy for Remote Enantioselective Functionalizations

N-Heterocyclic Carbene Catalysis via the α,β-Unsaturated Acyl Azolium

(2017) Changhe Zhang et al.   ACS Catalysis

N-Heterocyclic Carbene Catalyzed γ-Dihalomethylenation of Enals by Single-Electron Transfer

(2016) Wen Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cooperative Catalysis and Activation with N-Heterocyclic Carbenes

(2016) Michael H. Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent advances in N-heterocyclic carbene (NHC)-catalysed benzoin reactions

(2016) Rajeev S Menon et al.   Beilstein Journal of Organic Chemistry

Cyclobutenones and Benzocyclobutenones: Versatile Synthons in Organic Synthesis

(2016) Peng-hao Chen et al.   CHEMISTRY-A EUROPEAN JOURNAL

N-Heterocyclic Carbene Catalytic [4 + 2] Cyclization of 3-Alkylenyloxindoles with Enals: γ-Carbon Activation for Enantioselective Assembly of Spirocarbocyclic Oxindoles

(2016) Hong Yao et al.   JOURNAL OF ORGANIC CHEMISTRY

N-Heterocyclic carbene-catalyzed [4 + 2] cyclization of α,β-unsaturated carboxylic acids bearing γ-H with isatins: an enantioselective synthesis of spirocyclic oxindole–dihydropyranones

(2016) Ling Zhu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

N-Heterocyclic Carbene Catalyzed [4 + 2] Annulation Reactions with in Situ Generated Heterocyclic ortho-Quinodimethanes

(2016) Jianfeng Xu et al.   ORGANIC LETTERS

Annulation of o-Quinodimethanes through N-Heterocyclic Carbene Catalysis for the Synthesis of 1-Isochromanones

(2016) Daniel Janssen-Müller et al.   ORGANIC LETTERS

Enantioselective Cascade Reactions under N-Heterocyclic Carbene Catalysis

(2016) Efraím Reyes et al.   SYNTHESIS-STUTTGART

Enantioselective Assembly of Spirolactones through NHC-Catalyzed Remote γ-Carbon Addition of Enals with Isatins

(2016) Xianfeng Rong et al.   ACS Combinatorial Science

N-Heterocyclic carbene-catalyzed [4 + 2] annulation of α,β-unsaturated carboxylic acids: enantioselective synthesis of dihydropyridinones and spirocyclic oxindolodihydropyridinones

(2016) Wen-Qiang Jia et al.   Organic Chemistry Frontiers

Cooperative catalysis of N-heterocyclic carbene and Brønsted acid for a highly enantioselective route to unprotected spiro-indoline-pyrans

(2015) Youqiang Lin et al.   CHEMICAL COMMUNICATIONS

Organocatalytic Reactions Enabled by N-Heterocyclic Carbenes

(2015) Darrin M. Flanigan et al.   CHEMICAL REVIEWS

Recent advances in employing homoenolates generated by N-heterocyclic carbene (NHC) catalysis in carbon–carbon bond-forming reactions

(2015) Rajeev S. Menon et al.   CHEMICAL SOCIETY REVIEWS

Oxidative N-Heterocyclic Carbene-Catalyzed γ-Carbon Addition of Enals to Imines: Mechanistic Studies and Access to Antimicrobial Compounds

(2015) Peng-Cheng Zheng et al.   CHEMISTRY-A EUROPEAN JOURNAL

N-Heterocyclic Carbene Catalyzed Generation and [4+2] Annulation of Unsubstituted Dienolate - Enantioselective Synthesis of Spirocyclic Oxindolodihydropyranones

(2015) Jin-Tang Cheng et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Assembly of Spirocyclic Oxindole-dihydropyranones through NHC-Catalyzed Cascade Reaction of Isatins with N-Hydroxybenzotriazole Esters of α,β-Unsaturated Carboxylic Acid

(2015) Yonglei Que et al.   JOURNAL OF ORGANIC CHEMISTRY

N-heterocyclic carbene-catalyzed [4 + 2] cyclization of 2-bromo-2-enal with 3-alkylenyloxindoles: efficient assembly of spirocarbocyclic oxindole

(2015) Yuanwei Xie et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

An N-Heterocyclic Carbene-Catalyzed Oxidative γ-Aminoalkylation of Saturated Carboxylic Acids through in Situ Activation Strategy: Access to δ-Lactam

(2015) Yonglei Que et al.   ORGANIC LETTERS

γ-Carbon Activation through N-Heterocyclic Carbene/Brønsted Acids Cooperative Catalysis: A Highly Enantioselective Route to δ-Lactams

(2015) Yonglong Xiao et al.   ORGANIC LETTERS

Carbon–carbon bond activation of cyclobutenones enabled by the addition of chiral organocatalyst to ketone

(2015) Bao-Sheng Li et al.   Nature Communications

A quantum mechanical study of the mechanism and stereoselectivity of the N-heterocyclic carbene catalyzed [4 + 2] annulation reaction of enals with azodicarboxylates

(2015) Yang Wang et al.   Organic Chemistry Frontiers

On the Mechanism of N-Heterocyclic Carbene-Catalyzed Reactions Involving Acyl Azoliums

(2014) Jessada Mahatthananchai et al.   ACCOUNTS OF CHEMICAL RESEARCH

N-Heterocyclic Carbene Catalyzed Activation of Esters: A New Option for Asymmetric Domino Reactions

(2014) Pankaj Chauhan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Intermolecular Dynamic Kinetic Resolution Cooperatively Catalyzed by an N-Heterocyclic Carbene and a Lewis Acid

(2014) Zijun Wu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N-Heterocyclic Carbene-Catalyzed All Carbon-[4+2] Cyclocondensation ofα,β-Unsaturated Acyl Chlorides with 3-Alkylenyloxindoles

(2014) Litao Shen et al.   CHINESE JOURNAL OF CHEMISTRY

N-Heterocyclic Carbene-Catalyzed [3+4] Cycloaddition and Kinetic Resolution of Azomethine Imines

(2014) Ming Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An overview of N-heterocyclic carbenes

(2014) Matthew N. Hopkinson et al.   NATURE

Organocatalytic [4 + 2] cyclocondensation of α,β-unsaturated acyl chlorides with imines: highly enantioselective synthesis of dihydropyridinone and piperidine derivatives

(2014) Wen-Qiang Jia et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

N-Heterocyclic Carbene/Lewis Acid Strategy for the Stereoselective Synthesis of Spirocyclic Oxindole–Dihydropyranones

(2014) Zhaoxin Xiao et al.   ORGANIC LETTERS

A cooperative N-heterocyclic carbene/palladium catalysis system

(2014) Kun Liu et al.   Chemical Science

Benzene construction via organocatalytic formal [3+3] cycloaddition reaction

(2014) Tingshun Zhu et al.   Nature Communications

Highly Enantioselective γ-Amination by N-Heterocyclic Carbene Catalyzed [4+2] Annulation of Oxidized Enals and Azodicarboxylates

(2013) Xiang-Yu Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Functionalization of Benzylic C(sp3)H Bonds of Heteroaryl Aldehydes through N-Heterocyclic Carbene Organocatalysis

(2013) Xingkuan Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Remote 1,6-Stereocontrol by Iminium-mediated Organocatalytic Events

(2013) Martin J. Lear et al.   ChemCatChem

Acyl anion free N-heterocyclic carbene organocatalysis

(2013) Sarah J. Ryan et al.   CHEMICAL SOCIETY REVIEWS

Catalysis with N-Heterocyclic Carbenes under Oxidative Conditions

(2013) Suman De Sarkar et al.   CHEMISTRY-A EUROPEAN JOURNAL

Beyond Classical Reactivity Patterns: Shifting from 1,4- to 1,6-Additions in Regio- and Enantioselective Organocatalyzed Vinylogous Reactions of Olefinic Lactones with Enals and 2,4-Dienals

(2013) Luca Dell’Amico et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

β-Carbon activation of saturated carboxylic esters through N-heterocyclic carbene organocatalysis

(2013) Zhenqian Fu et al.   Nature Chemistry

An internal affair

(2013) Jeffrey W. Bode   Nature Chemistry

N-heterocyclic carbene-catalyzed reactions of C–C unsaturated bonds

(2013) Xiang-Yu Chen et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Organocatalytic Enantioselective γ-Aminoalkylation of Unsaturated Ester: Access to Pipecolic Acid Derivatives

(2013) Jianfeng Xu et al.   ORGANIC LETTERS

Enantioselective Cycloaddition Reactions of Ketenes Catalyzed by N-Heterocyclic Carbenes

(2013) Song Ye et al.   SYNLETT

Exploiting Acyl and Enol Azolium Intermediates via N-Hetero- cyclic Carbene-Catalyzed Reactions of α-Reducible Aldehydes

(2012) Harit U. Vora et al.   ADVANCED SYNTHESIS & CATALYSIS

A Continuum of Progress: Applications of N-Hetereocyclic Carbene Catalysis in Total Synthesis

(2012) Javier Izquierdo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic umpolung: N-heterocyclic carbenes and beyond

(2012) Xavier Bugaut et al.   CHEMICAL SOCIETY REVIEWS

Highly Regio-, Diastereo-, and Enantioselective 1,6- and 1,8-Additions of Azlactones to Di- and Trienyl N-Acylpyrroles

(2012) Daisuke Uraguchi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Oxidative γ-Addition of Enals to Trifluoromethyl Ketones: Enantioselectivity Control via Lewis Acid/N-Heterocyclic Carbene Cooperative Catalysis

(2012) Junming Mo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

NHCs in Asymmetric Organocatalysis: Recent Advances in Azolium Enolate Generation and Reactivity

(2012) Andrew Smith et al.   SYNTHESIS-STUTTGART

N-Heterocyclic Carbene-Catalyzed Cyclization of Unsaturated Acyl Chlorides and Ketones

(2011) Li-Tao Shen et al.   ADVANCED SYNTHESIS & CATALYSIS

N-Heterocyclic Carbene Catalyzed Domino Reactions

(2011) André Grossmann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Asymmetric 1,6-Addition Reactions

(2011) Akkattu T. Biju   ChemCatChem

Employing homoenolates generated by NHC catalysis in carbon–carbon bond-forming reactions: state of the art

(2011) Vijay Nair et al.   CHEMICAL SOCIETY REVIEWS

Cooperative Lewis acid/N-heterocyclic carbene catalysis

(2011) Daniel T. Cohen et al.   Chemical Science

Catalytic Asymmetric Formation of δ-Lactones from Unsaturated Acyl Halides

(2010) Paolo S. Tiseni et al.   CHEMISTRY-A EUROPEAN JOURNAL

α-Trifluoromethylated Carbanion Synthons

(2008) Kenji Uneyama et al.   ACCOUNTS OF CHEMICAL RESEARCH

N-Heterocyclic carbene catalysed β-lactam synthesis

(2008) Nicolas Duguet et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Chiral N-Heterocyclic Carbene Catalyzed Staudinger Reaction of Ketenes with Imines:  Highly Enantioselective Synthesis ofN-Boc β-Lactams

(2007) Yan-Rong Zhang et al.   ORGANIC LETTERS