Cyclobutenones and Benzocyclobutenones: Versatile Synthons in Organic Synthesis

Rhodium-Catalyzed [5 + 2 + 1] Cycloaddition of Ene–Vinylcyclopropanes and CO: Reaction Design, Development, Application in Natural Product Synthesis, and Inspiration for Developing New Reactions for Synthesis of Eight-Membered Carbocycles

(2015) Yi Wang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Nickel-Catalyzed Chemo-, Regio- and Diastereoselective Bond Formation through Proximal CC Cleavage of Benzocyclobutenones

(2015) Francisco Juliá-Hernández et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic C–C Bond Activations via Oxidative Addition to Transition Metals

(2015) Laetitia Souillart et al.   CHEMICAL REVIEWS

RhI-Catalyzed Benzo/[7+1] Cycloaddition of Cyclopropyl-Benzocyclobutenes and CO by Merging Thermal and Metal-Catalyzed CC Bond Cleavages

(2015) Xu-Fei Fu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Amino Acid Derived Phosphine-Catalyzed Enantioselective 1,4-Dipolar Spiroannulation of Cyclobutenones and Isatylidenemalononitrile

(2015) Yangyan Li et al.   CHEMISTRY-A EUROPEAN JOURNAL

Computational Study of Rh-Catalyzed Carboacylation of Olefins: Ligand-Promoted Rhodacycle Isomerization Enables Regioselective C–C Bond Functionalization of Benzocyclobutenones

(2015) Gang Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Rh-Catalyzed Carboacylation of C═N Bonds via C–C Activation of Benzocyclobutenones

(2015) Lin Deng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic intramolecular decarbonylative coupling of 3-aminocyclobutenones and alkenes: a unique approach to [3.1.0] bicycles

(2015) Xuan Zhou et al.   TETRAHEDRON

Cycloaddition of cyclobutenone and azomethine imine enabled by chiral isothiourea organic catalysts

(2015) Bao-Sheng Li et al.   Chemical Science

Rh-catalyzed reagent-free ring expansion of cyclobutenones and benzocyclobutenones

(2015) Peng-hao Chen et al.   Chemical Science

Carbon–carbon bond activation of cyclobutenones enabled by the addition of chiral organocatalyst to ketone

(2015) Bao-Sheng Li et al.   Nature Communications

Rhodium(I)-Catalyzed Decarbonylative Spirocyclization through CC Bond Cleavage of Benzocyclobutenones: An Efficient Approach to Functionalized Spirocycles

(2014) Tao Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Divergent Syntheses of Fused β-Naphthol and Indene Scaffolds by Rhodium-Catalyzed Direct and Decarbonylative Alkyne-Benzocyclobutenone Couplings

(2014) Peng-hao Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Coupling of Sterically Hindered Trisubstituted Olefins and Benzocyclobutenones by CC Activation: Total Synthesis and Structural Revision of Cycloinumakiol

(2014) Tao Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent Advances in Transition-Metal-Catalyzed Functionalization of Unstrained Carbon–Carbon Bonds

(2014) Feng Chen et al.   CHEMICAL REVIEWS

Investigation of Alkyne Regioselectivity in the Ni-Catalyzed Benzannulation of Cyclobutenones

(2014) Timo Stalling et al.   CHEMISTRY-A EUROPEAN JOURNAL

Intramolecular Diels–Alder Reactions of Cycloalkenones: Stereoselectivity, Lewis Acid Acceleration, and Halogen Substituent Effects

(2014) Hung V. Pham et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of 8,8-Dipropylbicyclo[4.2.0]octa-1,3,5-trien-7-one via Pd-catalyzed Intramolecular C-H Bond-Acylation

(2014)   ORGANIC SYNTHESES

Chiral β-Lactam Synthesis through the Enantioselective Reduction of Iminocyclobutenones and the Thermal Rearrangement of Aminocyclobutenones

(2014) Iwao Hachiya et al.   Asian Journal of Organic Chemistry

Direct activation of relatively unstrained carbon–carbon bonds in homogeneous systems

(2014) Alpay Dermenci et al.   Organic Chemistry Frontiers

Oxidative Addition of a Strained C–C Bond onto Electron-Rich Rhodium(I) at Room Temperature

(2013) Yusuke Masuda et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recent Advances in the Synthesis and Application of Benzocyclobutenones and Related Compounds

(2013) Ruben Martin et al.   SYNTHESIS-STUTTGART

Rhodium-Catalyzed Regioselective Carboacylation of Olefins: A CC Bond Activation Approach for Accessing Fused-Ring Systems

(2012) Tao Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Transition-Metal-Mediated Cleavage and Activation of C-C Single Bonds

(2012) Klaus Ruhland   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Highly Enantioselective Rh-Catalyzed Carboacylation of Olefins: Efficient Syntheses of Chiral Poly-Fused Rings

(2012) Tao Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Efficient Approach to 1,2-Diazepines via Formal Diazomethylene Insertion into the C–C bond of Cyclobutenones

(2012) Kenji Sugimoto et al.   ORGANIC LETTERS

N-Heterocyclic Carbene Dichotomy in Pd-Catalyzed Acylation of Aryl Chlorides via C–H Bond Functionalization

(2012) Areli Flores-Gaspar et al.   ORGANIC LETTERS

A Nickel-Catalyzed Benzannulation Approach to Aromatic Boronic Esters

(2011) Anne-Laure Auvinet et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cyclobutanes in Catalysis

(2011) Tobias Seiser et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Polycyclic Benzofused Nitrogen Heterocycles via a Tandem Ynamide Benzannulation/Ring-Closing Metathesis Strategy. Application in a Formal Total Synthesis of (+)-FR900482

(2011) Xiao Yin Mak et al.   JOURNAL OF ORGANIC CHEMISTRY

β-Carbon Elimination from Cyclobutanols: A Clean Access to Alkylrhodium Intermediates Bearing a Quaternary Stereogenic Center

(2011) Nicolai Cramer et al.   SYNLETT

Highly efficient synthesis of 3-amino-/alkylthio-cyclobut-2-en-1-ones based on the cyclization of acyl ketene dithioacetals

(2010) Yu-Long Zhao et al.   CHEMICAL COMMUNICATIONS

Metal-catalysed cleavage of carbon–carbon bonds

(2010) Masahiro Murakami et al.   CHEMICAL COMMUNICATIONS

Competitive Pathways in the Reaction of Lithium Oxy-ortho-quinodimethanes and Fischer Alkoxy Alkynyl Carbene Complexes: Synthesis of Highly Functionalised Seven-Membered Benzocarbocycles

(2010) Patricia García-García et al.   CHEMISTRY-A EUROPEAN JOURNAL

Cyclobutenone as a Highly Reactive Dienophile: Expanding Upon Diels−Alder Paradigms

(2010) Xiaohua Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pd-Catalyzed Intramolecular Acylation of Aryl Bromides via C−H Functionalization: A Highly Efficient Synthesis of Benzocyclobutenones

(2009) Paula Álvarez-Bercedo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereodivergent Synthesis of β-Lactams Using Thermal Rearrangement of Aminocyclobutenones

(2009) Iwao Hachiya et al.   ORGANIC LETTERS

Novel 3,4-Diazabenzotropone Compounds (2,3-Benzodiazepin-5-ones): Synthesis, Unique Reactivity, and Biological Evaluation

(2009) Yuji Matsuya et al.   ORGANIC LETTERS