A Continuum of Progress: Applications of N-Hetereocyclic Carbene Catalysis in Total Synthesis

An N-Heterocyclic Carbene/Lewis Acid Strategy for the Stereoselective Synthesis of Spirooxindole Lactones

(2012) Julien Dugal-Tessier et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N-Heterocyclic Carbene Catalyzed Oxidative Macrolactonization: Total Synthesis of (+)-Dactylolide

(2012) Kiyoun Lee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic umpolung: N-heterocyclic carbenes and beyond

(2012) Xavier Bugaut et al.   CHEMICAL SOCIETY REVIEWS

N-Heterocyclic Carbene-Catalyzed Enantioselective Annulation of Bromoenal and 1,3-Dicarbonyl Compounds

(2011) Fang-Gang Sun et al.   ADVANCED SYNTHESIS & CATALYSIS

Lewis Acid Activated Synthesis of Highly Substituted Cyclopentanes by the N-Heterocyclic Carbene Catalyzed Addition of Homoenolate Equivalents to Unsaturated Ketoesters

(2011) Daniel T. Cohen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Enantioselective Synthesis of α-Amino Acid Derivatives by an NHC-Catalyzed Intermolecular Stetter Reaction

(2011) Thierry Jousseaume et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N-Heterocyclic Carbene Catalyzed Domino Reactions

(2011) André Grossmann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total Synthesis and Absolute Stereochemistry of Seragakinone A

(2011) Akiomi Takada et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemoselective conversion of α-unbranched aldehydes to amides, esters, and carboxylic acids by NHC-catalysis

(2011) Satoru Kuwano et al.   CHEMICAL COMMUNICATIONS

Employing homoenolates generated by NHC catalysis in carbon–carbon bond-forming reactions: state of the art

(2011) Vijay Nair et al.   CHEMICAL SOCIETY REVIEWS

N-Heterocyclic Carbene-Catalyzed Redox Reactions of α-Functionalized Aldehydes

(2011) Zi-Qiang Rong et al.   CURRENT ORGANIC CHEMISTRY

Umpolung Catalysis in Benzoin-type and Stetter-type Reactions: From Enzymatic Performances to Bio-mimetic Organocatalytic Concepts

(2011) Pablo Dominguez de Maria et al.   CURRENT ORGANIC CHEMISTRY

Dual Secondary Amine/N-Heterocyclic Carbene Catalysis in the Asymmetric Michael/Cross-Benzoin Cascade Reaction of β-Oxo Sulfones with Enals

(2011) Dieter Enders et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Aripiprazole Versus Haloperidol in Combination With Clozapine for Treatment-Resistant Schizophrenia in Routine Clinical Care

(2011) Corrado Barbui et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Xanthone Natural Products viaN-Heterocyclic Carbene Catalysis: Total Synthesis of Atroviridin

(2011) Yumiko Suzuki et al.   JOURNAL OF ORGANIC CHEMISTRY

Total Syntheses of the Histone Deacetylase Inhibitors Largazole and 2-epi-Largazole: Application ofN-Heterocyclic Carbene Mediated Acylations in Complex Molecule Synthesis

(2011) Bo Wang et al.   JOURNAL OF ORGANIC CHEMISTRY

Catalytic Asymmetric Intermolecular Stetter Reaction of Enals with Nitroalkenes: Enhancement of Catalytic Efficiency through Bifunctional Additives

(2011) Daniel A. DiRocco et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Concise formal synthesis of (−)-7-deoxyloganin via N-heterocyclic carbene catalysed rearrangement of α,β-unsaturated enol esters

(2011) Lisa Candish et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Enantioselective Synthesis of Dihydropyridinones via NHC-Catalyzed Aza-Claisen Reaction

(2011) Benedikt Wanner et al.   ORGANIC LETTERS

NHC-Catalyzed/Titanium(IV)−Mediated Highly Diastereo- and Enantioselective Dimerization of Enals

(2011) Daniel T. Cohen et al.   ORGANIC LETTERS

Highly Enantioselective Intermolecular Stetter Reactions of β-Aryl Acceptors: α-Ketoester Moiety as Handle for Activation and Synthetic Manipulations

(2011) Eduardo Sánchez-Larios et al.   ORGANIC LETTERS

Highly Stereoselective Synthesis of 1,2,3-Trisubstituted Indanes via Oxidative N-Heterocyclic Carbene-Catalyzed Cascades

(2011) Anup Biswas et al.   ORGANIC LETTERS

Asymmetric, Protecting-Group-Free Total Synthesis of (−)-Englerin A

(2010) Qianghui Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

NHC-Catalyzed Michael Addition to α,β-Unsaturated Aldehydes by Redox Activation

(2010) Suman De Sarkar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Separation and identification of three epimeric pairs of new C-glucosyl anthrones from Rumex dentatus by on-line high performance liquid chromatography–circular dichroism analysis

(2010) Jing-Jing Zhu et al.   JOURNAL OF CHROMATOGRAPHY A

Highly Chemoselective Direct Crossed Aliphatic−Aromatic Acyloin Condensations with Triazolium-Derived Carbene Catalysts

(2010) Sarah E. O’Toole et al.   JOURNAL OF ORGANIC CHEMISTRY

An Enantioselective Claisen Rearrangement Catalyzed by N-Heterocyclic Carbenes

(2010) Juthanat Kaeobamrung et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

NHC Catalyzed Oxidations of Aldehydes to Esters: Chemoselective Acylation of Alcohols in Presence of Amines

(2010) Suman De Sarkar et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cooperative catalysis by carbenes and Lewis acids in a highly stereoselective route to γ-lactams

(2010) Dustin E. A. Raup et al.   Nature Chemistry

Enantioselective Formal Synthesis of (−)-Englerin A via a Rh-Catalyzed [4 + 3] Cycloaddition Reaction

(2010) Jing Xu et al.   ORGANIC LETTERS

Catalytic Enantioselective Total Syntheses of Bakkenolides I, J, and S: Application of a Carbene-Catalyzed Desymmetrization

(2010) Eric M. Phillips et al.   ORGANIC LETTERS

NHC-Catalyzed Intramolecular Redox Amidation for the Synthesis of Functionalized Lactams

(2010) Karen Thai et al.   ORGANIC LETTERS

The Total Synthesis of (−)-7-Deoxyloganin viaN-Heterocyclic Carbene Catalyzed Rearrangement of α,β-Unsaturated Enol Esters

(2010) Lisa Candish et al.   ORGANIC LETTERS

Oxidative Amidation and Azidation of Aldehydes by NHC Catalysis

(2010) Suman De Sarkar et al.   ORGANIC LETTERS

Synthesis of the Monomeric Unit of the Lomaiviticin Aglycon

(2009) K. C. Nicolaou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Naturally Occurring Iridoids, Secoiridoids and Their Bioactivity. An Updated Review, Part 3

(2009) Biswanath Dinda et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Highly Enantioselective Benzoin Condensation Reactions Involving a Bifunctional Protic Pentafluorophenyl-Substituted Triazolium Precatalyst

(2009) Louise Baragwanath et al.   JOURNAL OF ORGANIC CHEMISTRY

Catalytic Asymmetric Intermolecular Stetter Reaction of Heterocyclic Aldehydes with Nitroalkenes: Backbone Fluorination Improves Selectivity

(2009) Daniel A. DiRocco et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

N-Heterocyclic Carbene-Catalyzed Generation of α,β-Unsaturated Acyl Imidazoliums: Synthesis of Dihydropyranones by their Reaction with Enolates

(2009) Sarah J. Ryan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantio- and Diastereoselective Intermolecular Stetter Reaction of Glyoxamide and Alkylidene Ketoamides

(2009) Qin Liu et al.   ORGANIC LETTERS

A Concise, Biomimetic Total Synthesis of (+)-Davanone

(2009) Karen C. Morrison et al.   ORGANIC LETTERS

Impact of Solvent Polarity on N-Heterocyclic Carbene-Catalyzed β-Protonations of Homoenolate Equivalents

(2009) Brooks E. Maki et al.   ORGANIC LETTERS

Formal synthesis of salinosporamide A via NHC-catalyzed intramolecular lactonization

(2009) Justin R. Struble et al.   TETRAHEDRON

Antitumor and antimetastatic actions of anthrone-C-glucoside, cassialoin isolated from Cassia garrettiana heartwood in colon 26-bearing mice

(2008) Yoshiyuki Kimura et al.   CANCER SCIENCE

Nucleophilic Carbene Catalyzed Synthesis of 1,2 Amino Alcohols Via Azidation of Epoxy Aldehydes

(2008) Harit U. Vora et al.   JOURNAL OF ORGANIC CHEMISTRY

N-Heterocyclic Carbene-Catalyzed Nucleophilic Aroylation of Fluorobenzenes

(2008) Yumiko Suzuki et al.   JOURNAL OF ORGANIC CHEMISTRY

Lessons from Nature: Biomimetic Organocatalytic Carbon−Carbon Bond Formations§

(2008) Dieter Enders et al.   JOURNAL OF ORGANIC CHEMISTRY

Cyclic Ketimines as Superior Electrophiles for NHC-Catalyzed Homoenolate Additions with Broad Scope and Low Catalyst Loadings

(2008) Michael Rommel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct Amination of Homoenolates Catalyzed byN-Heterocyclic Carbenes

(2008) Audrey Chan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Diastereo- and Enantioselective Additions of Homoenolates to Nitrones Catalyzed byN-Heterocyclic Carbenes

(2008) Eric M. Phillips et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Asymmetric Intermolecular Stetter Reaction of Glyoxamides with Alkylidenemalonates

(2008) Qin Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Biological and Pharmacological Activities of Iridoids: Recent Developments

(2008) Rosa Tundis et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

N-Heterocyclic Carbene-Catalyzed Oxidation of Unactivated Aldehydes to Esters

(2008) Brooks E. Maki et al.   ORGANIC LETTERS

Englerin A, a Selective Inhibitor of Renal Cancer Cell Growth, fromPhyllanthus engleri

(2008) Ranjala Ratnayake et al.   ORGANIC LETTERS

A síntese dos sesquiterpenos baquenolidas

(2008) Timothy John Brocksom et al.   QUIMICA NOVA

Formal synthesis of salinosporamide A using a nickel-catalyzed reductive aldol cyclization–lactonization as a key step

(2008) Isabel Villanueva Margalef et al.   TETRAHEDRON

N-Heterocyclic carbene-catalyzed oxidations

(2008) Brooks E. Maki et al.   TETRAHEDRON

Total Synthesis and Structure Assignment of the Anthrone C-Glycoside Cassialoin

(2007) Yasuhito Koyama et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Towards the total synthesis of FD-838: modular enantioselective assembly of the core

(2007) Arturo Orellana et al.   CHEMICAL COMMUNICATIONS

Enantioselective, NHC-Catalyzed Bicyclo-β-Lactam Formation via Direct Annulations of Enals and UnsaturatedN-Sulfonyl Ketimines

(2007) Ming He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY