标题
Thinking small: towards microRNA-based therapeutics for anxiety disorders
作者
关键词
-
出版物
EXPERT OPINION ON INVESTIGATIONAL DRUGS
Volume 24, Issue 4, Pages 529-542
出版商
Informa Healthcare
发表日期
2015-01-08
DOI
10.1517/13543784.2014.997873
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Long-term safety and efficacy of microRNA-targeted therapy in chronic hepatitis C patients
- (2014) Meike H. van der Ree et al. ANTIVIRAL RESEARCH
- Mechanisms to medicines: elucidating neural and molecular substrates of fear extinction to identify novel treatments for anxiety disorders
- (2014) Olena Bukalo et al. BRITISH JOURNAL OF PHARMACOLOGY
- Environmental enrichment modulates glucocorticoid receptor expression and reduces anxiety in Indian field male mouse Mus booduga through up-regulation of microRNA-124a
- (2014) Ragu Varman Durairaj et al. GENERAL AND COMPARATIVE ENDOCRINOLOGY
- Serum microRNA expression signatures identified from genome-wide microRNA profiling serve as novel noninvasive biomarkers for diagnosis and recurrence of bladder cancer
- (2014) Xiumei Jiang et al. INTERNATIONAL JOURNAL OF CANCER
- Serum and amygdala microRNA signatures of posttraumatic stress: Fear correlation and biomarker potential
- (2014) Nagaraja S. Balakathiresan et al. JOURNAL OF PSYCHIATRIC RESEARCH
- Anxiety Disorders in Primary Care
- (2014) Heidi Combs et al. MEDICAL CLINICS OF NORTH AMERICA
- Global CNS Transduction of Adult Mice by Intravenously Delivered rAAVrh.8 and rAAVrh.10 and Nonhuman Primates by rAAVrh.10
- (2014) Bin Yang et al. MOLECULAR THERAPY
- miR-1202 is a primate-specific and brain-enriched microRNA involved in major depression and antidepressant treatment
- (2014) Juan Pablo Lopez et al. NATURE MEDICINE
- Evaluation of quantitative miRNA expression platforms in the microRNA quality control (miRQC) study
- (2014) Pieter Mestdagh et al. NATURE METHODS
- Amygdala-Dependent Fear Memory Consolidation via miR-34a and Notch Signaling
- (2014) Brian George Dias et al. NEURON
- MicroRNA 135 Is Essential for Chronic Stress Resiliency, Antidepressant Efficacy, and Intact Serotonergic Activity
- (2014) Orna Issler et al. NEURON
- Basal microRNA expression patterns in reward circuitry of selectively bred high-responder and low-responder rats vary by brain region and genotype
- (2014) David E. Hamilton et al. PHYSIOLOGICAL GENOMICS
- Neurobehavioral, neuropathological and biochemical profiles in a novel mouse model of co-morbid post-traumatic stress disorder and mild traumatic brain injury
- (2014) Joseph O. Ojo et al. Frontiers in Behavioral Neuroscience
- miRNA Expression Profiles in Cerebrospinal Fluid and Blood of Patients with Acute Ischemic Stroke
- (2014) Sofie Sølvsten Sørensen et al. Translational Stroke Research
- When less is more - microRNAs and psychiatric disorders
- (2013) E. Kolshus et al. ACTA PSYCHIATRICA SCANDINAVICA
- Circulating MicroRNAs: A Novel Class of Potential Biomarkers for Diagnosing and Prognosing Central Nervous System Diseases
- (2013) Xue-Feng Jin et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Anxiolytic drug discovery: what are the novel approaches and how can we improve them?
- (2013) Adam Michael Stewart et al. Expert Opinion on Drug Discovery
- microRNAs as novel antidepressant targets: converging effects of ketamine and electroconvulsive shock therapy in the rat hippocampus
- (2013) Richard M. O'Connor et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Progress in microRNA delivery
- (2013) Yu Zhang et al. JOURNAL OF CONTROLLED RELEASE
- MicroRNA-182 Regulates Amygdala-Dependent Memory Formation
- (2013) E. M. Griggs et al. JOURNAL OF NEUROSCIENCE
- 50 years of hurdles and hope in anxiolytic drug discovery
- (2013) Guy Griebel et al. NATURE REVIEWS DRUG DISCOVERY
- MicroRNAs and other non-coding RNAs as targets for anticancer drug development
- (2013) Hui Ling et al. NATURE REVIEWS DRUG DISCOVERY
- Treatment of HCV Infection by Targeting MicroRNA
- (2013) Harry L.A. Janssen et al. NEW ENGLAND JOURNAL OF MEDICINE
- Acute Stress Alters Amygdala microRNA miR-135a and miR-124 Expression: Inferences for Corticosteroid Dependent Stress Response
- (2013) Cecilia Mannironi et al. PLoS One
- Chronic Academic Stress Increases a Group of microRNAs in Peripheral Blood
- (2013) Manami Honda et al. PLoS One
- Translational Approaches to Anxiety: Focus on Genetics, Fear Extinction and Brain Imaging
- (2013) Angelika Erhardt et al. Current Psychiatry Reports
- The origin, function, and diagnostic potential of extracellular microRNAs in human body fluids
- (2013) Hongwei Liang et al. Wiley Interdisciplinary Reviews-RNA
- Systemic Delivery of Tyrosine-Mutant AAV Vectors Results in Robust Transduction of Neurons in Adult Mice
- (2013) Asako Iida et al. Biomed Research International
- MicroRNAs as biomarkers for CNS disease
- (2013) Pooja Rao et al. Frontiers in Molecular Neuroscience
- Therapeutic Delivery of MicroRNA-29b by Cationic Lipoplexes for Lung Cancer
- (2013) Yun Wu et al. Molecular Therapy-Nucleic Acids
- Therapeutic Action of Fluoxetine is Associated with a Reduction in Prefrontal Cortical miR-1971 Expression Levels in a Mouse Model of Posttraumatic Stress Disorder
- (2013) Ulrike Schmidt et al. Frontiers in Psychiatry
- MicroRNA-target interactions: new insights from genome-wide approaches
- (2012) Dooyoung Lee et al. Annals of the New York Academy of Sciences
- Genetic variation in hippocampal microRNA expression differences in C57BL/6 J X DBA/2 J (BXD) recombinant inbred mouse strains
- (2012) Michael J Parsons et al. BMC GENOMICS
- Hippocampal microRNA-132 mediates stress-inducible cognitive deficits through its acetylcholinesterase target
- (2012) G. Shaltiel et al. Brain Structure & Function
- Clinical Applications for microRNAs in Cancer
- (2012) S P Nana-Sinkam et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Blood microRNA changes in depressed patients during antidepressant treatment
- (2012) Luisella Bocchio-Chiavetto et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- Lost in translation. New unexplored avenues for neuropsychopharmacology: epigenetics and microRNAs
- (2012) Daniela Tardito et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Identification of seven serum microRNAs from a genome-wide serum microRNA expression profile as potential noninvasive biomarkers for malignant astrocytomas
- (2012) Cuihua Yang et al. INTERNATIONAL JOURNAL OF CANCER
- Micro-Managing the Circadian Clock: The Role of microRNAs in Biological Timekeeping
- (2012) Neel Mehta et al. JOURNAL OF MOLECULAR BIOLOGY
- Environmental enrichment upregulates micro-RNA-183 and alters acetylcholinesterase splice variants to reduce anxiety-like behavior in the little Indian field mouse (Mus booduga)
- (2012) Durairaj Ragu Varman et al. JOURNAL OF NEUROSCIENCE RESEARCH
- microRNAs in cancer management
- (2012) Yi W Kong et al. LANCET ONCOLOGY
- Lifetime experiences, the brain and personalized medicine: An integrative perspective
- (2012) Bruce S. McEwen et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Allele-specific FKBP5 DNA demethylation mediates gene–childhood trauma interactions
- (2012) Torsten Klengel et al. NATURE NEUROSCIENCE
- MicroRNA profiling: approaches and considerations
- (2012) Colin C. Pritchard et al. NATURE REVIEWS GENETICS
- Regulated microRNAs in the CSF of patients with multiple sclerosis: A case-control study
- (2012) A. Haghikia et al. NEUROLOGY
- MicroRNAs miR-144/144* and miR-16 in peripheral blood are potential biomarkers for naturalistic stress in healthy Japanese medical students
- (2012) Sakurako Katsuura et al. NEUROSCIENCE LETTERS
- Secreted microRNAs: a new form of intercellular communication
- (2012) Xi Chen et al. TRENDS IN CELL BIOLOGY
- MiR-122 in hepatic function and liver diseases
- (2012) Jun Hu et al. Protein & Cell
- The Path to microRNA Therapeutics in Psychiatric and Neurodegenerative Disorders
- (2012) Anthony W. S. Chan et al. Frontiers in Genetics
- High resolution of microRNA signatures in human whole saliva
- (2011) Rushi S. Patel et al. ARCHIVES OF ORAL BIOLOGY
- The age of anxiety: role of animal models of anxiolytic action in drug discovery
- (2011) John F Cryan et al. BRITISH JOURNAL OF PHARMACOLOGY
- Blood Cell Origin of Circulating MicroRNAs: A Cautionary Note for Cancer Biomarker Studies
- (2011) C. C. Pritchard et al. Cancer Prevention Research
- microRNA-34c is a novel target to treat dementias
- (2011) Athanasios Zovoilis et al. EMBO JOURNAL
- MicroRNA therapeutics
- (2011) J A Broderick et al. GENE THERAPY
- MicroRNA expression in rat brain exposed to repeated inescapable shock: differential alterations in learned helplessness vs. non-learned helplessness
- (2011) Neil R. Smalheiser et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- microRNA as Repressors of Stress-Induced Anxiety: The Case of Amygdalar miR-34
- (2011) S. Haramati et al. JOURNAL OF NEUROSCIENCE
- Role of microRNAs in central nervous system development and pathology
- (2011) Karla F. Meza-Sosa et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Little things on which happiness depends: microRNAs as novel therapeutic targets for the treatment of anxiety and depression
- (2011) R M O'Connor et al. MOLECULAR PSYCHIATRY
- Extracellular microRNA: A new source of biomarkers
- (2011) Alton Etheridge et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- MicroRNA history: Discovery, recent applications, and next frontiers
- (2011) Maria I. Almeida et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- The brain-specific microRNA miR-128b regulates the formation of fear-extinction memory
- (2011) Quan Lin et al. NATURE NEUROSCIENCE
- Non-coding RNAs in human disease
- (2011) Manel Esteller NATURE REVIEWS GENETICS
- The GABA system in anxiety and depression and its therapeutic potential
- (2011) Hanns Möhler NEUROPHARMACOLOGY
- The involvement of FK506-binding protein 51 (FKBP5) in the behavioral and neuroendocrine effects of chronic social defeat stress
- (2011) Jakob Hartmann et al. NEUROPHARMACOLOGY
- Increased sensitivity to the effects of chronic social defeat stress in an innately anxious mouse strain
- (2011) H.M. Savignac et al. NEUROSCIENCE
- MicroRNAs: Meta-controllers of gene expression in synaptic activity emerge as genetic and diagnostic markers of human disease
- (2011) Stephanie Ceman et al. PHARMACOLOGY & THERAPEUTICS
- Behavioural consequences of two chronic psychosocial stress paradigms: Anxiety without depression
- (2011) David A. Slattery et al. PSYCHONEUROENDOCRINOLOGY
- Chronic non-invasive corticosterone administration abolishes the diurnal pattern of tph2 expression
- (2011) Nina C. Donner et al. PSYCHONEUROENDOCRINOLOGY
- Posttranscriptional Upregulation by MicroRNAs
- (2011) Shobha Vasudevan Wiley Interdisciplinary Reviews-RNA
- Convergent functional genomics of anxiety disorders: translational identification of genes, biomarkers, pathways and mechanisms
- (2011) H Le-Niculescu et al. Translational Psychiatry
- Human microRNAs miR-22, miR-138-2, miR-148a, and miR-488 Are Associated with Panic Disorder and Regulate Several Anxiety Candidate Genes and Related Pathways
- (2010) Margarita Muiños-Gimeno et al. BIOLOGICAL PSYCHIATRY
- RNA mechanisms in CNS systems and disorders
- (2010) Kai-Christian Sonntag et al. BRAIN RESEARCH
- MicroRNA dysregulation in psychiatric disease
- (2010) Brooke H. Miller et al. BRAIN RESEARCH
- Childhood adversities and adult psychopathology in the WHO World Mental Health Surveys
- (2010) Ronald C. Kessler et al. BRITISH JOURNAL OF PSYCHIATRY
- Circulating microRNAs: Association with disease and potential use as biomarkers
- (2010) Glen Reid et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- A five-microRNA signature identified from genome-wide serum microRNA expression profiling serves as a fingerprint for gastric cancer diagnosis
- (2010) Rui Liu et al. EUROPEAN JOURNAL OF CANCER
- Metabotropic glutamate receptor 7: At the interface of cognition and emotion
- (2010) Richard M. O'Connor et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- The Pharmacologic Treatment of Anxiety Disorders
- (2010) Lakshmi N. Ravindran et al. JOURNAL OF CLINICAL PSYCHIATRY
- Serum Response Factor Promotes Resilience to Chronic Social Stress through the Induction of FosB
- (2010) V. Vialou et al. JOURNAL OF NEUROSCIENCE
- Early Life Stress Enhances Behavioral Vulnerability to Stress through the Activation of REST4-Mediated Gene Transcription in the Medial Prefrontal Cortex of Rodents
- (2010) S. Uchida et al. JOURNAL OF NEUROSCIENCE
- Animal models of neuropsychiatric disorders
- (2010) Eric J Nestler et al. NATURE NEUROSCIENCE
- Animal models of depression and anxiety: What do they tell us about human condition?
- (2010) I.D. Neumann et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Stress induces region specific alterations in microRNAs expression in mice
- (2009) Arianna Rinaldi et al. BEHAVIOURAL BRAIN RESEARCH
- Pharmacology of epigenetics in brain disorders
- (2009) Pritika Narayan et al. BRITISH JOURNAL OF PHARMACOLOGY
- MicroRNAs: Target Recognition and Regulatory Functions
- (2009) David P. Bartel CELL
- Changes in Brain MicroRNAs Contribute to Cholinergic Stress Reactions
- (2009) Ari Meerson et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Imaging genetics of anxiety disorders
- (2009) Katharina Domschke et al. NEUROIMAGE
- Genetics of anxiety and trauma-related disorders
- (2009) S.D. Norrholm et al. NEUROSCIENCE
- A single anti-microRNA antisense oligodeoxyribonucleotide (AMO) targeting multiple microRNAs offers an improved approach for microRNA interference
- (2009) Yanjie Lu et al. NUCLEIC ACIDS RESEARCH
- The role of FKBP5, a co-chaperone of the glucocorticoid receptor in the pathogenesis and therapy of affective and anxiety disorders
- (2009) Elisabeth B. Binder PSYCHONEUROENDOCRINOLOGY
- Using hippocampal microRNA expression differences between mouse inbred strains to characterise miRNA function
- (2008) Michael J. Parsons et al. MAMMALIAN GENOME
- LNA-mediated microRNA silencing in non-human primates
- (2008) Joacim Elmén et al. NATURE
- Evidence for Selective microRNAs and Their Effectors as Common Long-Term Targets for the Actions of Mood Stabilizers
- (2008) Rulun Zhou et al. NEUROPSYCHOPHARMACOLOGY
- Circulating microRNAs as stable blood-based markers for cancer detection
- (2008) P. S. Mitchell et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Proteomic profiling of exosomes: Current perspectives
- (2008) Richard J. Simpson et al. PROTEOMICS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started