Posttranscriptional Upregulation by MicroRNAs

Arabidopsis Argonaute10 Specifically Sequesters miR166/165 to Regulate Shoot Apical Meristem Development

(2011) Hongliang Zhu et al.   CELL

The let-7 microRNA interfaces extensively with the translation machinery to regulate cell differentiation

(2011) Xavier C. Ding et al.   CELL CYCLE

Cell cycle control of microRNA-mediated translation regulation

(2011) Shobha Vasudevan et al.   CELL CYCLE

HuR-dependent loading of miRNA RISC to the mRNA encoding the Ras-related small GTPase RhoB controls its translation during UV-induced apoptosis

(2011) V Glorian et al.   CELL DEATH AND DIFFERENTIATION

Limiting Ago protein restricts RNAi and microRNA biogenesis during early development in Xenopus laevis

(2011) E. Lund et al.   GENES & DEVELOPMENT

Post-transcriptional generation of miRNA variants by multiple nucleotidyl transferases contributes to miRNA transcriptome complexity

(2011) S. K. Wyman et al.   GENOME RESEARCH

Translational Control of TOP2A Influences Doxorubicin Efficacy

(2011) S. Srikantan et al.   MOLECULAR AND CELLULAR BIOLOGY

A KLF4-miRNA-206 Autoregulatory Feedback Loop Can Promote or Inhibit Protein Translation Depending upon Cell Context

(2011) C.-C. Lin et al.   MOLECULAR AND CELLULAR BIOLOGY

Integrative Regulatory Mapping Indicates that the RNA-Binding Protein HuR Couples Pre-mRNA Processing and mRNA Stability

(2011) Neelanjan Mukherjee et al.   MOLECULAR CELL

Poly(ADP-Ribose) Regulates Stress Responses and MicroRNA Activity in the Cytoplasm

(2011) Anthony K.L. Leung et al.   MOLECULAR CELL

Transcriptome-wide Analysis of Regulatory Interactions of the RNA-Binding Protein HuR

(2011) Svetlana Lebedeva et al.   MOLECULAR CELL

CPEB and two poly(A) polymerases control miR-122 stability and p53 mRNA translation

(2011) David M. Burns et al.   NATURE

miR-122 activates hepatitis C virus translation by a specialized mechanism requiring particular RNA components

(2011) Ashley P. E. Roberts et al.   NUCLEIC ACIDS RESEARCH

Activation of a microRNA response in trans reveals a new role for poly(A) in translational repression

(2011) Emiliano P. Ricci et al.   NUCLEIC ACIDS RESEARCH

Masking the 5' terminal nucleotides of the hepatitis C virus genome by an unconventional microRNA-target RNA complex

(2011) E. S. Machlin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Posttranscriptional activation of gene expression in Xenopus laevis oocytes by microRNA-protein complexes (microRNPs)

(2011) R. D. Mortensen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

3′ uridylation and the regulation of RNA function in the cytoplasm

(2010) Chris J. Norbury   BIOCHEMICAL SOCIETY TRANSACTIONS

P-Body Loss Is Concomitant with Formation of a Messenger RNA Storage Domain in Mouse Oocytes1

(2010) Matyas Flemr et al.   BIOLOGY OF REPRODUCTION

MicroRNA-223 regulates Glut4 expression and cardiomyocyte glucose metabolism

(2010) Han Lu et al.   CARDIOVASCULAR RESEARCH

MicroRNAs: From Decay to Decoy

(2010) Michaela Beitzinger et al.   CELL

miR-328 Functions as an RNA Decoy to Modulate hnRNP E2 Regulation of mRNA Translation in Leukemic Blasts

(2010) Anna M. Eiring et al.   CELL

Interplay between microRNAs and RNA-binding proteins determines developmental processes

(2010) Martijn Kedde et al.   CELL CYCLE

Activation of hepatitis c virus translation by a liver-specific microRNA

(2010) Michael Niepmann   CELL CYCLE

Emerging Roles for Natural MicroRNA Sponges

(2010) Margaret S. Ebert et al.   CURRENT BIOLOGY

MicroRNA Activity Is Suppressed in Mouse Oocytes

(2010) Jun Ma et al.   CURRENT BIOLOGY

MicroRNA Function Is Globally Suppressed in Mouse Oocytes and Early Embryos

(2010) Nayoung Suh et al.   CURRENT BIOLOGY

Hen1 is required for oocyte development and piRNA stability in zebrafish

(2010) Leonie M Kamminga et al.   EMBO JOURNAL

Two PABPC1-binding sites in GW182 proteins promote miRNA-mediated gene silencing

(2010) Eric Huntzinger et al.   EMBO JOURNAL

Mammalian microRNAs: experimental evaluation of novel and previously annotated genes

(2010) H. R. Chiang et al.   GENES & DEVELOPMENT

Structural Basis of Binding of P-body-associated Proteins GW182 and Ataxin-2 by the Mlle Domain of Poly(A)-binding Protein

(2010) Guennadi Kozlov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Estradiol Suppresses NF- B Activation through Coordinated Regulation of let-7a and miR-125b in Primary Human Macrophages

(2010) A. J. Murphy et al.   JOURNAL OF IMMUNOLOGY

MicroRNA-466l Upregulates IL-10 Expression in TLR-Triggered Macrophages by Antagonizing RNA-Binding Protein Tristetraprolin-Mediated IL-10 mRNA Degradation

(2010) F. Ma et al.   JOURNAL OF IMMUNOLOGY

Human Ago2 Is Required for Efficient MicroRNA 122 Regulation of Hepatitis C Virus RNA Accumulation and Translation

(2010) J. A. Wilson et al.   JOURNAL OF VIROLOGY

A Functional Requirement for PAK1 Binding to the KH(2) Domain of the Fragile X Protein-Related FXR1

(2010) Evonne Say et al.   MOLECULAR CELL

Pathogenic LRRK2 negatively regulates microRNA-mediated translational repression

(2010) Stephan Gehrke et al.   NATURE

A dicer-independent miRNA biogenesis pathway that requires Ago catalysis

(2010) Sihem Cheloufi et al.   NATURE

Mammalian microRNAs predominantly act to decrease target mRNA levels

(2010) Huili Guo et al.   NATURE

A coding-independent function of gene and pseudogene mRNAs regulates tumour biology

(2010) Laura Poliseno et al.   NATURE

Pumilio turns on microRNA function

(2010) Robinson Triboulet et al.   NATURE CELL BIOLOGY

A Pumilio-induced RNA structure switch in p27-3′ UTR controls miR-221 and miR-222 accessibility

(2010) Martijn Kedde et al.   NATURE CELL BIOLOGY

The mechanism of eukaryotic translation initiation and principles of its regulation

(2010) Richard J. Jackson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structural insights into the human GW182-PABC interaction in microRNA-mediated deadenylation

(2010) Martin Jinek et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cell stress is related to re-localization of Argonaute 2 and to decreased RNA interference in human cells

(2010) Anke Detzer et al.   NUCLEIC ACIDS RESEARCH

Down-Regulation of a Host MicroRNA by a Herpesvirus saimiri Noncoding RNA

(2010) D. Cazalla et al.   SCIENCE

A Novel miRNA Processing Pathway Independent of Dicer Requires Argonaute2 Catalytic Activity

(2010) D. Cifuentes et al.   SCIENCE

Quiescent Fibroblasts Exhibit High Metabolic Activity

(2010) Johanna M. S. Lemons et al.   PLOS BIOLOGY

MicroRNA mir-346 targets the 5′-untranslated region of receptor-interacting protein 140 (RIP140) mRNA and up-regulates its protein expression

(2009) Nien-Pei Tsai et al.   BIOCHEMICAL JOURNAL

Regulatory RNAs in Bacteria

(2009) Lauren S. Waters et al.   CELL

Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets

(2009) Nahum Sonenberg et al.   CELL

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

TUT4 in Concert with Lin28 Suppresses MicroRNA Biogenesis through Pre-MicroRNA Uridylation

(2009) Inha Heo et al.   CELL

Mili Interacts with Tudor Domain-Containing Protein 1 in Regulating Spermatogenesis

(2009) Jianquan Wang et al.   CURRENT BIOLOGY

Mechanisms of miRNA-mediated post-transcriptional regulation in animal cells

(2009) Marina Chekulaeva et al.   CURRENT OPINION IN CELL BIOLOGY

Activation of gene expression by small RNA

(2009) Kathrin S. Fröhlich et al.   CURRENT OPINION IN MICROBIOLOGY

Repression of C. elegans microRNA targets at the initiation level of translation requires GW182 proteins

(2009) Xavier C Ding et al.   EMBO JOURNAL

Vasa promotes Drosophila germline stem cell differentiation by activating mei-P26 translation by directly interacting with a (U)-rich motif in its 3' UTR

(2009) N. Liu et al.   GENES & DEVELOPMENT

HuR recruits let-7/RISC to repress c-Myc expression

(2009) H. H. Kim et al.   GENES & DEVELOPMENT

Selective stabilization of mammalian microRNAs by 3' adenylation mediated by the cytoplasmic poly(A) polymerase GLD-2

(2009) T. Katoh et al.   GENES & DEVELOPMENT

Non-coding RNAs: regulators of disease

(2009) Ryan J Taft et al.   JOURNAL OF PATHOLOGY

The Silencing Domain of GW182 Interacts with PABPC1 To Promote Translational Repression and Degradation of MicroRNA Targets and Is Required for Target Release

(2009) L. Zekri et al.   MOLECULAR AND CELLULAR BIOLOGY

Mammalian miRNA RISC Recruits CAF1 and PABP to Affect PABP-Dependent Deadenylation

(2009) Marc R. Fabian et al.   MOLECULAR CELL

Drosophila Argonaute1 and Argonaute2 Employ Distinct Mechanisms for Translational Repression

(2009) Shintaro Iwasaki et al.   MOLECULAR CELL

Zcchc11-dependent uridylation of microRNA directs cytokine expression

(2009) Matthew R. Jones et al.   NATURE CELL BIOLOGY

Rapamycin activation of 4E-BP prevents parkinsonian dopaminergic neuron loss

(2009) Luke S Tain et al.   NATURE NEUROSCIENCE

microRNAs at the synapse

(2009) Gerhard Schratt   NATURE REVIEWS NEUROSCIENCE

Decapping is preceded by 3′ uridylation in a novel pathway of bulk mRNA turnover

(2009) Olivia S Rissland et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Lin28 recruits the TUTase Zcchc11 to inhibit let-7 maturation in mouse embryonic stem cells

(2009) John P Hagan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

LIN-28 and the poly(U) polymerase PUP-2 regulate let-7 microRNA processing in Caenorhabditis elegans

(2009) Nicolas J Lehrbach et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

microRNA-Mediated Messenger RNA Deadenylation Contributes to Translational Repression in Mammalian Cells

(2009) Traude H. Beilharz et al.   PLoS One

Cell-cell contact globally activates microRNA biogenesis

(2009) H.-W. Hwang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The DAZL and PABP families: RNA-binding proteins with interrelated roles in translational control in oocytes

(2009) Matthew Brook et al.   REPRODUCTION

Importance of the C-terminal domain of the human GW182 protein TNRC6C for translational repression

(2009) J. T. Zipprich et al.   RNA

The C-terminal half of human Ago2 binds to multiple GW-rich regions of GW182 and requires GW182 to mediate silencing

(2009) S. L. Lian et al.   RNA

Translational control by cytoplasmic polyadenylation in Xenopus oocytes

(2008) Helois E. Radford et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Breaking the Code of Polyadenylation-Induced Translation

(2008) Joel D. Richter   CELL

Position-Dependent Function for a Tandem MicroRNA miR-122-Binding Site Located in the Hepatitis C Virus RNA Genome

(2008) Catherine L. Jopling et al.   Cell Host & Microbe

Importance of Translation and Nonnucleolytic Ago Proteins for On-Target RNA Interference

(2008) Ligang Wu et al.   CURRENT BIOLOGY

microRNA-122 stimulates translation of hepatitis C virus RNA

(2008) Jura Inga Henke et al.   EMBO JOURNAL

Phosphorylation of 4E-BP by LRRK2 affects the maintenance of dopaminergic neurons in Drosophila

(2008) Yuzuru Imai et al.   EMBO JOURNAL

MILI, a PIWI-interacting RNA-binding Protein, Is Required for Germ Line Stem Cell Self-renewal and Appears to Positively Regulate Translation

(2008) Yingdee Unhavaithaya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Decoding ARE-mediated decay: is microRNA part of the equation?

(2008) Christopher von Roretz et al.   JOURNAL OF CELL BIOLOGY

Identification of GW182 and its novel isoform TNGW1 as translational repressors in Ago2-mediated silencing

(2008) S. Li et al.   JOURNAL OF CELL SCIENCE

Lin28 Mediates the Terminal Uridylation of let-7 Precursor MicroRNA

(2008) Inha Heo et al.   MOLECULAR CELL

MicroRNA-10a Binds the 5′UTR of Ribosomal Protein mRNAs and Enhances Their Translation

(2008) Ulf Andersson Ørom et al.   MOLECULAR CELL

TheXenopus laevisIsoform of G Protein-Coupled Receptor 3 (GPR3) Is a Constitutively Active Cell Surface Receptor that Participates in Maintaining Meiotic Arrest inX. laevisOocytes

(2008) James Deng et al.   MOLECULAR ENDOCRINOLOGY

Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes

(2008) Oliver H. Tam et al.   NATURE

GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay

(2008) Ana Eulalio et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

MicroRNA-mediated up-regulation of an alternatively polyadenylated variant of the mouse cytoplasmic β-actin gene

(2008) Tanay Ghosh et al.   NUCLEIC ACIDS RESEARCH

MicroRNA-repressed mRNAs contain 40S but not 60S components

(2008) B. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coexpression of Argonaute-2 enhances RNA interference toward perfect match binding sites

(2008) S. Diederichs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of specific let-7 microRNA binding complexes in Caenorhabditis elegans

(2008) S.-P. Chan et al.   RNA

Deadenylation is a widespread effect of miRNA regulation

(2008) A. Eulalio et al.   RNA

Proliferating Cells Express mRNAs with Shortened 3' Untranslated Regions and Fewer MicroRNA Target Sites

(2008) R. Sandberg et al.   SCIENCE

Control of the Reversibility of Cellular Quiescence by the Transcriptional Repressor HES1

(2008) L. Sang et al.   SCIENCE