Little things on which happiness depends: microRNAs as novel therapeutic targets for the treatment of anxiety and depression

The Endocannabinoid System and the Treatment of Mood and Anxiety Disorders

(2012) Matthew Hill et al.   CNS & Neurological Disorders-Drug Targets

Non-Viral Nucleic Acid Delivery: Key Challenges and Future Directions

(2012) Mahmoud Elsabahy et al.   Current Drug Delivery

The age of anxiety: role of animal models of anxiolytic action in drug discovery

(2011) John F Cryan et al.   BRITISH JOURNAL OF PHARMACOLOGY

MicroRNAs in addiction: adaptation's middlemen?

(2011) M D Li et al.   MOLECULAR PSYCHIATRY

The 'real world' utility of miRNA patents: lessons learned from expressed sequence tags

(2011) Bonnie W McLeod et al.   NATURE BIOTECHNOLOGY

MicroRNAs can generate thresholds in target gene expression

(2011) Shankar Mukherji et al.   NATURE GENETICS

The brain-specific microRNA miR-128b regulates the formation of fear-extinction memory

(2011) Quan Lin et al.   NATURE NEUROSCIENCE

MicroRNA Expression Profiling of the Porcine Developing Brain

(2011) Agnieszka Podolska et al.   PLoS One

Strain differences in the chronic mild stress animal model of depression

(2010) Hsiao Hua Wu et al.   BEHAVIOURAL BRAIN RESEARCH

Human microRNAs miR-22, miR-138-2, miR-148a, and miR-488 Are Associated with Panic Disorder and Regulate Several Anxiety Candidate Genes and Related Pathways

(2010) Margarita Muiños-Gimeno et al.   BIOLOGICAL PSYCHIATRY

MicroRNA dysregulation in psychiatric disease

(2010) Brooke H. Miller et al.   BRAIN RESEARCH

Thelet-7microRNA reduces tumor growth in mouse models of lung cancer

(2010) Aurora Esquela-Kerscher et al.   CELL CYCLE

MicroRNA Regulation in Cardiovascular Disease

(2010) P.A. da Costa Martins et al.   CURRENT DRUG TARGETS

Neuronal circuits of fear extinction

(2010) Cyril Herry et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

S.04.04 Stress-induced alterations in hippocampal and amygdalar microRNAs: effects of lithium

(2010) R.M. O'Connor et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Riluzole Normalizes Early-Life Stress-Induced Visceral Hypersensitivity in Rats: Role of Spinal Glutamate Reuptake Mechanisms

(2010) Romain–Daniel Gosselin et al.   GASTROENTEROLOGY

Genetic variants and abnormal processing of pre-miR-182, a circadian clock modulator, in major depression patients with late insomnia

(2010) Ester Saus et al.   HUMAN MOLECULAR GENETICS

Sex differences in the activity of signalling pathways and expression of G-protein-coupled receptor kinases in the neonatal ventral hippocampal lesion model of schizophrenia

(2010) Evgeny Bychkov et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

A polymorphism in the microRNA-30e precursor associated with major depressive disorder risk and P300 waveform

(2010) Yong Xu et al.   JOURNAL OF AFFECTIVE DISORDERS

Cross talk between microRNA and epigenetic regulation in adult neurogenesis

(2010) Keith E. Szulwach et al.   JOURNAL OF CELL BIOLOGY

Early Life Stress Enhances Behavioral Vulnerability to Stress through the Activation of REST4-Mediated Gene Transcription in the Medial Prefrontal Cortex of Rodents

(2010) S. Uchida et al.   JOURNAL OF NEUROSCIENCE

Review: Clock genes at the heart of depression

(2010) David J Kennaway   JOURNAL OF PSYCHOPHARMACOLOGY

Postexposure protection of non-human primates against a lethal Ebola virus challenge with RNA interference: a proof-of-concept study

(2010) Thomas W Geisbert et al.   LANCET

MicroRNA Functions in Stress Responses

(2010) Anthony K.L. Leung et al.   MOLECULAR CELL

Advances in molecular genetics of panic disorder

(2010) E Maron et al.   MOLECULAR PSYCHIATRY

Striatal microRNA controls cocaine intake through CREB signalling

(2010) Jonathan A. Hollander et al.   NATURE

MeCP2 controls BDNF expression and cocaine intake through homeostatic interactions with microRNA-212

(2010) Heh-In Im et al.   NATURE NEUROSCIENCE

New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory?

(2010) Wei Deng et al.   NATURE REVIEWS NEUROSCIENCE

MicroRNAs and target site screening reveals a pre-microRNA-30e variant associated with schizophrenia

(2010) Yong Xu et al.   SCHIZOPHRENIA RESEARCH

A Glutamate Pathway to Faster-Acting Antidepressants?

(2010) J. F. Cryan et al.   SCIENCE

MiR-16 Targets the Serotonin Transporter: A New Facet for Adaptive Responses to Antidepressants

(2010) A. Baudry et al.   SCIENCE

Deep brain stimulation: from neurology to psychiatry?

(2010) Paul Krack et al.   TRENDS IN NEUROSCIENCES

Stress induces region specific alterations in microRNAs expression in mice

(2009) Arianna Rinaldi et al.   BEHAVIOURAL BRAIN RESEARCH

Polymorphism distribution and structural conservation in RNA-sensing Toll-like receptors 3, 7, and 8 in pigs

(2009) Takeya Morozumi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Glucocorticoid signaling and stress-related limbic susceptibility pathway: About receptors, transcription machinery and microRNA

(2009) E.R. de Kloet et al.   BRAIN RESEARCH

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Regulation of MicroRNA Biogenesis: A miRiad of mechanisms

(2009) Brandi N Davis et al.   Cell Communication and Signaling

MicroRNA-mediated Regulation of Ubc9 Expression in Cancer Cells

(2009) F. Wu et al.   CLINICAL CANCER RESEARCH

Allele variants in functional MicroRNA target sites of the neurotrophin-3 receptor gene (NTRK3) as susceptibility factors for anxiety disorders

(2009) Margarita Muiños-Gimeno et al.   HUMAN MUTATION

MicroRNAs as a target for novel antipsychotics: a systematic review of an emerging field

(2009) Timothy G. Dinan   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Targeted electrode-based modulation of neural circuits for depression

(2009) Helen S. Mayberg   JOURNAL OF CLINICAL INVESTIGATION

Rapid Onset of Antidepressant Action

(2009) Rodrigo Machado-Vieira et al.   JOURNAL OF CLINICAL PSYCHIATRY

Neuron-specific RNA interference using lentiviral vectors

(2009) Troels Tolstrup Nielsen et al.   JOURNAL OF GENE MEDICINE

Changes in Brain MicroRNAs Contribute to Cholinergic Stress Reactions

(2009) Ari Meerson et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis

(2009) Gabriele Siegel et al.   NATURE CELL BIOLOGY

Many roads to maturity: microRNA biogenesis pathways and their regulation

(2009) Julia Winter et al.   NATURE CELL BIOLOGY

miR-124 regulates adult neurogenesis in the subventricular zone stem cell niche

(2009) Li-Chun Cheng et al.   NATURE NEUROSCIENCE

Biogenesis of small RNAs in animals

(2009) V. Narry Kim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Stress differentially modulates mRNA expression for corticotrophin-releasing hormone receptors in hypothalamus, hippocampus and pituitary of prairie voles

(2009) Hossein Pournajafi-Nazarloo et al.   NEUROPEPTIDES

Regression of murine lung tumors by the let-7 microRNA

(2009) P Trang et al.   ONCOGENE

Transcription Factors in Long-Term Memory and Synaptic Plasticity

(2009) Cristina M. Alberini   PHYSIOLOGICAL REVIEWS

Antagonism of microRNA-126 suppresses the effector function of TH2 cells and the development of allergic airways disease

(2009) J. Mattes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pathophysiology of depression: Role of sleep and the melatonergic system

(2009) Venkataramanujan Srinivasan et al.   PSYCHIATRY RESEARCH

Therapeutic Silencing of MicroRNA-122 in Primates with Chronic Hepatitis C Virus Infection

(2009) R. E. Lanford et al.   SCIENCE

miRNAs: small changes, widespread effects

(2008) Sam EV Linsen et al.   CELL RESEARCH

Characterization of the vulnerability to repeated stress in Fischer 344 rats: possible involvement of microRNA-mediated down-regulation of the glucocorticoid receptor

(2008) Shusaku Uchida et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The circadian basis of mood disorders: Recent developments and treatment implications

(2008) Palmiero Monteleone et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Circadian rhythm disturbances in depression

(2008) Anne Germain et al.   HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL

Not miR-ly small RNAs: Big potential for microRNAs in therapy

(2008) Tara M. Love et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Expression of microRNAs and their precursors in synaptic fractions of adult mouse forebrain

(2008) Giovanni Lugli et al.   JOURNAL OF NEUROCHEMISTRY

Adult Neurogenesis, Mental Health, and Mental Illness: Hope or Hype?

(2008) A. J. Eisch et al.   JOURNAL OF NEUROSCIENCE

Impaired Fear Extinction Learning and Cortico-Amygdala Circuit Abnormalities in a Common Genetic Mouse Strain

(2008) K. Hefner et al.   JOURNAL OF NEUROSCIENCE

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(2008) M. W. Walker et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Gene therapy of inherited diseases

(2008) Alain Fischer et al.   LANCET

Thinking about RNA? MicroRNAs in the brain

(2008) Christian Barbato et al.   MAMMALIAN GENOME

Nonviral Methods for siRNA Delivery

(2008) Kun Gao et al.   MOLECULAR PHARMACEUTICS

MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

(2008) Thomas Thum et al.   NATURE

LNA-mediated microRNA silencing in non-human primates

(2008) Joacim Elmén et al.   NATURE

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

(2008) Witold Filipowicz et al.   NATURE REVIEWS GENETICS

Biological principles of microRNA-mediated regulation: shared themes amid diversity

(2008) Alex S. Flynt et al.   NATURE REVIEWS GENETICS

Evidence of an enhanced central 5HT response in irritable bowel syndrome and in the rat maternal separation model

(2008) s. o'mahony et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Exercise, Learned Helplessness, and the Stress-Resistant Brain

(2008) Benjamin N. Greenwood et al.   NEUROMOLECULAR MEDICINE

Evidence for Selective microRNAs and Their Effectors as Common Long-Term Targets for the Actions of Mood Stabilizers

(2008) Rulun Zhou et al.   NEUROPSYCHOPHARMACOLOGY

Novel Drugs and Therapeutic Targets for Severe Mood Disorders

(2008) Sanjay J Mathew et al.   NEUROPSYCHOPHARMACOLOGY

Safety and Efficacy of Gene Transfer for Leber's Congenital Amaurosis

(2008) Albert M. Maguire et al.   NEW ENGLAND JOURNAL OF MEDICINE

Spatial Relational Memory Requires Hippocampal Adult Neurogenesis

(2008) David Dupret et al.   PLoS One

Suppression of non-small cell lung tumor development by the let-7 microRNA family

(2008) M. S. Kumar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-373 induces expression of genes with complementary promoter sequences

(2008) R. F. Place et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Strain differences in anxiety-like behavior: Association with corticotropin-releasing factor

(2007) J SHEPARD et al.   BEHAVIOURAL BRAIN RESEARCH

Glucocorticoid Receptor mRNA Expression in the Hippocampal Formation of Male Rats before and after Pubertal Development in Response to Acute or Repeated Stress

(2007) Russell D. Romeo et al.   NEUROENDOCRINOLOGY

Posttranscriptional control of neuronal development by microRNA networks

(2007) Fen-Biao Gao   TRENDS IN NEUROSCIENCES