Phosphine-Catalyzed Activation of Vinylcyclopropanes: Rearrangement of Vinylcyclopropylketones to Cycloheptenones

Multifunctional chiral phosphine-catalyzed [3+2] annulation of Morita–Baylis–Hillman carbonates with cyclopentenones: asymmetric synthesis of 4-oxo-hexahydropentalenes

(2018) Chang Wang et al.   CHEMICAL COMMUNICATIONS

Phosphine-catalyzed [5+1] annulation of δ-sulfonamido-substituted enones with N-sulfonylimines: a facile synthesis of tetrahydropyridines

(2018) Leijie Zhou et al.   Chemical Science

Regio- and Diastereoselective Construction of Spirocyclopenteneoxindoles through Phosphine-Catalyzed [3 + 2] Annulation of Methyleneindolinone with Alkynoate Derivatives

(2017) Jiayong Zhang et al.   JOURNAL OF ORGANIC CHEMISTRY

Hydroxy-Assisted Regio- and Stereoselective Synthesis of Functionalized 4-Methylenepyrrolidine Derivatives via Phosphine-Catalyzed [3 + 2] Cycloaddition of Allenoates with o-Hydroxyaryl Azomethine Ylides

(2017) Zhusheng Huang et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthetic applications of vinyl cyclopropane opening

(2017) Marta Meazza et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Enantioselective Synthesis of Tetrahydropyridines/Piperidines via Stepwise [4 + 2]/[2 + 2] Cyclizations

(2017) Zhen Wang et al.   ORGANIC LETTERS

Functionalized Tetrahydropyridines by Enantioselective Phosphine-Catalyzed Aza-[4 + 2] Cycloaddition of N-Sulfonyl-1-aza-1,3-dienes with Vinyl Ketones

(2017) Huamin Wang et al.   ORGANIC LETTERS

Enantioselective Phosphine-Catalyzed Allylic Alkylations of mix-Indene with MBH Carbonates

(2017) Junyou Zhang et al.   ORGANIC LETTERS

Construction of Complex 1,3-Cyclohexadienes via Phosphine-Catalyzed (4 + 2) Annulations of δ-Acetoxy Allenoates and Ketones

(2017) Yuwen Zhang et al.   ORGANIC LETTERS

Phosphine-Catalyzed Sequential [4 + 3] Domino Annulation/Allylic Alkylation Reaction of MBH Carbonates: Efficient Construction of Seven-Membered Heterocycles

(2017) Junlong Chen et al.   ORGANIC LETTERS

PPh3-Mediated [4 + 2]- and [4 + 1]-Annulations of Maleimides with Azoalkenes: Access to Fused Tetrahydropyridazine/Pyrrolidinedione and Spiro-dihydropyrazole/Pyrrolidinedione Derivatives

(2017) Rong Huang et al.   ORGANIC LETTERS

PPh3-Catalyzed [3 + 2] Spiroannulation of 1C,3N-Bisnucleophiles Derived from Secondary β-Ketoamides with δ-Acetoxy Allenoate: A Route to Functionalized Spiro N-Heterocyclic Derivatives

(2017) Jiaojiao Xing et al.   ORGANIC LETTERS

Enantioselective [4 + 1]-Annulation of α,β-Unsaturated Imines with Allylic Carbonates Catalyzed by a Hybrid P-Chiral Phosphine Oxide–Phosphine

(2017) Hanyuan Li et al.   ORGANIC LETTERS

Phosphine-Catalyzed Enantioselective [4 + 2] Annulation of o-Quinone Methides with Allene Ketones

(2017) Zhen Wang et al.   ORGANIC LETTERS

Organocatalytic Cloke–Wilson Rearrangement: DABCO-Catalyzed Ring Expansion of Cyclopropyl Ketones to 2,3-Dihydrofurans

(2017) Jingfang Zhang et al.   ORGANIC LETTERS

Phosphine-Catalyzed [4 + 2] Annulation of Allenoate with Sulfamate-Derived Cyclic Imines: A Reaction Mode Involving γ′-Carbon of α-Substituted Allenoate

(2017) Biming Mao et al.   ORGANIC LETTERS

Phosphine-Catalyzed Asymmetric (3+2) Annulations of δ-Acetoxy Allenoates with 2-Naphthols

(2017) Dong Wang et al.   ORGANIC LETTERS

Palladium(0)-Catalyzed Dearomative [3 + 2] Cycloaddition of 3-Nitroindoles with Vinylcyclopropanes: An Entry to Stereodefined 2,3-Fused Cyclopentannulated Indoline Derivatives

(2017) Maxime Laugeois et al.   ORGANIC LETTERS

Catalyst-controlled regioselectivity in phosphine catalysis: the synthesis of spirocyclic benzofuranones via regiodivergent [3 + 2] annulations of aurones and an allenoate

(2017) Huanzhen Ni et al.   Chemical Science

Chiral phosphine-mediated intramolecular [3 + 2] annulation: enhanced enantioselectivity by achiral Brønsted acid

(2017) Weijun Yao et al.   Chemical Science

Enantioselective Construction of All-Carbon Quaternary Stereogenic Centers by Using Phosphine Catalysis

(2017) Huilin Li et al.   Asian Journal of Organic Chemistry

Amino Acid-Derived Bifunctional Phosphines for Enantioselective Transformations

(2016) Tianli Wang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Engaging Allene-Derived Zwitterions in an Unprecedented Mode of Asymmetric [3+2]-Annulation Reaction

(2016) Muthukumar G. Sankar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Phosphine-mediated Highly Enantioselective Spirocyclization with Ketimines as Substrates

(2016) Xiaoyu Han et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bifunctional-Phosphine-Catalyzed Sequential Annulations of Allenoates and Ketimines: Construction of Functionalized Poly-heterocycle Rings

(2016) Erqing Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric preparation of polysubstituted cyclopentanes by synergistic Pd(0)/amine catalyzed formal [3+2] cycloadditions of vinyl cyclopropanes with enals

(2016) Maxime Laugeois et al.   CHEMICAL COMMUNICATIONS

Advances in Annulation Reactions Initiated by Phosphorus Ylides Generated in situ

(2016) Rong Zhou et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Phosphine-Catalyzed Enantioselective [2+4] Cycloaddition to Synthesize Pyrrolidin-2-one Fused Dihydropyrans Using α-Substituted Allenoates as C2 Synthons

(2016) Chang Wang et al.   JOURNAL OF ORGANIC CHEMISTRY

Phosphine-Catalyzed [2 + 4] Annulation of Allenoates with Thiazolone-Derived Alkenes: Synthesis of Functionalized 6,7-Dihydro-5H-pyrano[2,3-d]thiazoles

(2016) Chang Wang et al.   ORGANIC LETTERS

Phosphine-Catalyzed Enantioselective [4 + 3] Annulation of Allenoates with C,N-Cyclic Azomethine Imines: Synthesis of Quinazoline-Based Tricyclic Heterocycles

(2016) Chunhao Yuan et al.   ORGANIC LETTERS

Asymmetric [3 + 2] Cycloaddition of Vinylcyclopropanes and α,β-Unsaturated Aldehydes by Synergistic Palladium and Organocatalysis

(2016) Kim Søholm Halskov et al.   ORGANIC LETTERS

Bifunctional Organo/Metal Cooperatively Catalyzed [3 + 2] Annulation of para-Quinone Methides with Vinylcyclopropanes: Approach to Spiro[4.5]deca-6,9-diene-8-ones

(2016) Zhenbo Yuan et al.   ORGANIC LETTERS

Lewis Base and Brønsted Base Dual-Catalyzed Formal [4+3] Cyclo­addition Reaction: Synthesis of Aza-Spirocycloheptane Oxindole

(2016) Peng-Fei Xu et al.   SYNLETT

Recent Advances in the Synthesis and Reactivity of Vinylcyclopropanes

(2016) Srinivasan Chandrasekaran et al.   SYNTHESIS-STUTTGART

Rhodium-Catalyzed [5 + 2 + 1] Cycloaddition of Ene–Vinylcyclopropanes and CO: Reaction Design, Development, Application in Natural Product Synthesis, and Inspiration for Developing New Reactions for Synthesis of Eight-Membered Carbocycles

(2015) Yi Wang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Phosphine-Catalyzed β,γ-Umpolung Domino Reaction of Allenic Esters: Facile Synthesis of Tetrahydrobenzofuranones Bearing a Chiral Tetrasubstituted Stereogenic Carbon Center

(2015) Shinobu Takizawa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Phosphine-Catalyzed Addition/Cycloaddition Domino Reactions of β′-Acetoxy Allenoate: Highly Stereoselective Access to 2-Oxabicyclo[3.3.1]nonane and Cyclopenta[a]pyrrolizine

(2015) Yiting Gu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Construction of dispirocyclohexanes via amine-catalyzed [2 + 2 + 2] annulations of Morita–Baylis–Hillman acetates with exocyclic alkenes

(2015) Rongshun Chen et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

[4 + 3] Cycloadditions with Bromo-Substituted Morita–Baylis–Hillman Adducts of Isatins and N-(ortho-Chloromethyl)aryl Amides

(2015) Gu Zhan et al.   ORGANIC LETTERS

Divergent amine-catalyzed [2+2] annulation of allenoates with azodicarboxylates: facile synthesis of 1,2-diazetidines

(2015) Silong Xu et al.   TETRAHEDRON LETTERS

Asymmetric Synthesis of Spiropyrazolones through Phosphine-Catalyzed [4+1] Annulation

(2014) Xiaoyu Han et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Phosphine catalysis of allenes with electrophiles

(2014) Zhiming Wang et al.   CHEMICAL SOCIETY REVIEWS

Highly Enantioselective [3+2] Cycloaddition of Vinylcyclopropane with Nitroalkenes Catalyzed by Palladium(0) with a Chiral Bis(tert-amine) Ligand

(2014) Feng Wei et al.   CHEMISTRY-A EUROPEAN JOURNAL

Highly Enantioselective Synthesis of 3,4-Dihydropyrans through a Phosphine-Catalyzed [4+2] Annulation of Allenones and β,γ-Unsaturated α-Keto Esters

(2014) Weijun Yao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An organic thiyl radical catalyst for enantioselective cyclization

(2014) Takuya Hashimoto et al.   Nature Chemistry

Distinct reactivity of Morita–Baylis–Hillman acetates as a novel C2 component in amine-catalyzed [2 + 2 + 2] and [2 + 4] annulations

(2013) Rongshun Chen et al.   CHEMICAL COMMUNICATIONS

Advances in nucleophilic phosphine catalysis of alkenes, allenes, alkynes, and MBHADs

(2013) Yi Chiao Fan et al.   CHEMICAL COMMUNICATIONS

Vinylcyclopropane Derivatives in Transition-Metal-Catalyzed Cycloadditions for the Synthesis of Carbocyclic Compounds

(2013) Lei Jiao et al.   JOURNAL OF ORGANIC CHEMISTRY

Nickel-Catalyzed Cycloaddition of Vinylcyclopropanes to Imines

(2013) Rihoko Tombe et al.   ORGANIC LETTERS

Phosphine-Catalyzed [4 + 2] Annulation of γ-Substituent Allenoates: Facile Access to Functionalized Spirocyclic Skeletons

(2013) Erqing Li et al.   ORGANIC LETTERS

Rhodium-Catalyzed Asymmetric Amination of Allylic Trichloroacetimidates

(2013) Hien Nguyen et al.   SYNTHESIS-STUTTGART

Phosphine-Catalyzed [3+2] and [4+3] Annulation Reactions of C,N-Cyclic Azomethine Imines with Allenoates

(2012) Chengfeng Jing et al.   ADVANCED SYNTHESIS & CATALYSIS

Catalytic Asymmetric [4+2] Annulation Initiated by an Aza-Rauhut-Currier Reaction: Facile Entry to Highly Functionalized Tetrahydropyridines

(2012) Zugui Shi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fe-Catalyzed Allylic C–C-Bond Activation: Vinylcyclopropanes As Versatile a1,a3,d5-Synthons in Traceless Allylic Substitutions and [3 + 2]-Cycloadditions

(2012) André P. Dieskau et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Diastereo- and Enantioselective Formal [3 + 2]-Cycloadditions of Substituted Vinylcyclopropanes

(2012) Barry M. Trost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Phosphine-Triggered Tandem Annulation between Morita–Baylis–Hillman Carbonates and Dinucleophiles: Facile Syntheses of Oxazepanes, Thiazepanes, and Diazepanes

(2012) Rong Zhou et al.   ORGANIC LETTERS

Palladium-Catalyzed Asymmetric Formal [3+2] Cycloaddition of Vinyl Cyclopropanes and β,γ-Unsaturated α-Keto Esters: An Effective Route to Highly Functionalized Cyclopentanes

(2012) Liang-yong Mei et al.   ORGANOMETALLICS

Highly enantioselective [4 + 2] annulations catalyzed by amino acid-based phosphines: Synthesis of functionalized cyclohexenes and 3-spirocyclohexene-2-oxindoles

(2012) Fangrui Zhong et al.   Chemical Science

Allenoate-derived 1,5-, 1,7-, and 1,9-zwitterions as highly versatile coupling-partners for phosphine-triggered cycloaddition reactions

(2012) Wei Meng et al.   Chemical Science

Palladium-Catalyzed Diastereo- and Enantioselective Synthesis of Substituted Cyclopentanes through a Dynamic Kinetic Asymmetric Formal [3+2]-Cycloaddition of Vinyl Cyclopropanes and Alkylidene Azlactones

(2011) Barry M. Trost et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Versatile Enantioselective [3+2] Cyclization between Imines and Allenoates Catalyzed by Dipeptide-Based Phosphines

(2011) Xiaoyu Han et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Enantioselective [3+2] Annulation of Morita-Baylis-Hillman Adducts Mediated by L-Threonine-Derived Phosphines: Synthesis of 3-Spirocyclopentene-2-oxindoles having Two Contiguous Quaternary Centers

(2011) Fangrui Zhong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Phosphine-Catalyzed [4 + 1] Annulation between α,β-Unsaturated Imines and Allylic Carbonates: Synthesis of 2-Pyrrolines

(2011) Junjun Tian et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective [3 + 2] Cycloaddition of Allenes to Acrylates Catalyzed by Dipeptide-Derived Phosphines: Facile Creation of Functionalized Cyclopentenes Containing Quaternary Stereogenic Centers

(2011) Xiaoyu Han et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Phosphine-Catalyzed Annulations of Azomethine Imines: Allene-Dependent [3 + 2], [3 + 3], [4 + 3], and [3 + 2 + 3] Pathways

(2011) Risong Na et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Palladium-Catalyzed Vinylcyclopropane (3 + 2) Cycloaddition Approach to the Melodinus Alkaloids

(2011) Alexander F. G. Goldberg et al.   ORGANIC LETTERS

From Discovery to Application: 50 Years of the Vinylcyclopropane-Cyclopentene Rearrangement and Its Impact on the Synthesis of Natural Products

(2010) Tomas Hudlicky et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

2-(Acetoxymethyl)buta-2,3-dienoate, a Versatile 1,4-Biselectrophile for Phosphine-Catalyzed (4 +n) Annulations with 1,n-Bisnucleophiles (n= 1, 2)

(2010) Qiongmei Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rh(I)-Catalyzed [(3 + 2) + 1] Cycloaddition of 1-Yne/Ene-vinylcyclopropanes and CO: Homologous Pauson−Khand Reaction and Total Synthesis of (±)-α-Agarofuran

(2010) Lei Jiao et al.   ORGANIC LETTERS

Phosphane-Catalyzed [3+2] Annulation of Allenoates with Aldehydes: A Simple and Efficient Synthesis of 2-Alkylidenetetrahydrofurans

(2009) Silong Xu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Phosphine-Catalyzed [4 + 3] Annulation for the Synthesis of Highly Functionalized Bicyclo[3.2.2]nonadienes

(2009) Suqing Zheng et al.   ORGANIC LETTERS

Phosphine-triggered synthesis of functionalized cyclic compounds

(2008) Long-Wu Ye et al.   CHEMICAL SOCIETY REVIEWS

Rh(I)-Catalyzed Intramolecular [3 + 2] Cycloaddition oftrans-Vinylcyclopropane-enes

(2008) Lei Jiao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Diastereoselective Synthesis of Tetrahydrofurans via Palladium(0)-Catalyzed [3 + 2] Cycloaddition of Vinylcyclopropanes and Aldehydes

(2008) Andrew T. Parsons et al.   ORGANIC LETTERS