Enantioselective Construction of All-Carbon Quaternary Stereogenic Centers by Using Phosphine Catalysis

Amino Acid-Derived Bifunctional Phosphines for Enantioselective Transformations

(2016) Tianli Wang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Synthetic Strategies toward Natural Products Containing Contiguous Stereogenic Quaternary Carbon Atoms

(2016) Martin Büschleb et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective [3 + 2] annulation of α-substituted allenoates with β,γ-unsaturatedN-sulfonylimines catalyzed by a bifunctional dipeptide phosphine

(2016) Huanzhen Ni et al.   Beilstein Journal of Organic Chemistry

Catalytic Enantioselective Desymmetrization Reactions to All-Carbon Quaternary Stereocenters

(2016) Xing-Ping Zeng et al.   CHEMICAL REVIEWS

Recent developments in the synthesis and utilization of chiral β-aminophosphine derivatives as catalysts or ligands

(2016) Wenbo Li et al.   CHEMICAL SOCIETY REVIEWS

Asymmetric Roadmap to Diverse Polycyclic Benzopyrans via Phosphine-Catalyzed Enantioselective [4 + 2]-Annulation Reaction

(2016) Adithi Danda et al.   ORGANIC LETTERS

Enantioselective synthesis of 3-fluoro-3-allyl-oxindoles via phosphine-catalyzed asymmetric γ-addition of 3-fluoro-oxindoles to 2,3-butadienoates

(2015) Tianli Wang et al.   CHEMICAL COMMUNICATIONS

Amino Acid Derived Phosphine-Catalyzed Enantioselective 1,4-Dipolar Spiroannulation of Cyclobutenones and Isatylidenemalononitrile

(2015) Yangyan Li et al.   CHEMISTRY-A EUROPEAN JOURNAL

Phosphine-Catalyzed Enantioselective Intramolecular [3+2] Annulations To Generate Fused Ring Systems

(2015) Sarah Yunmi Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Direct Mannich Reactions of Cyclic β-Ketoesters Catalyzed by Chiral Phosphine via a Novel Dual-Reagent Catalysis

(2015) Yan-Peng Lou et al.   ORGANIC LETTERS

Highly enantioselective construction of tertiary thioethers and alcohols via phosphine-catalyzed asymmetric γ-addition reactions of 5H-thiazol-4-ones and 5H-oxazol-4-ones: scope and mechanistic understandings

(2015) Tianli Wang et al.   Chemical Science

Phosphine-Catalyzed Asymmetric Formal [4+2] Tandem Cyclization of Activated Dienes with Isatylidenemalononitriles: Enantioselective Synthesis of Multistereogenic Spirocyclic Oxindoles

(2014) Fang-Le Hu et al.   ADVANCED SYNTHESIS & CATALYSIS

Phosphine-Catalyzed Enantioselective γ-Addition of 3-Substituted Oxindoles to 2,3-Butadienoates and 2-Butynoates: Use of Prochiral Nucleophiles

(2014) Tianli Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Phosphine-Catalyzed Annulations of 4,4-Dicyano-2-Methylenebut-3-enoates with Maleimides and Maleic Anhydride

(2014) Xiao-Nan Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biphenyl-Derived Phosphepines as Chiral Nucleophilic Catalysts: Enantioselective [4+1] Annulations To Form Functionalized Cyclopentenes

(2014) Daniel T. Ziegler et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Synthesis of Spiropyrazolones through Phosphine-Catalyzed [4+1] Annulation

(2014) Xiaoyu Han et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral phosphines in nucleophilic organocatalysis

(2014) Yumei Xiao et al.   Beilstein Journal of Organic Chemistry

Phosphine-catalyzed [4+1] annulation of 1,3-(aza)dienes with maleimides: highly efficient construction of azaspiro[4.4]nonenes

(2014) Mei Yang et al.   CHEMICAL COMMUNICATIONS

Phosphine-catalyzed asymmetric [4+1] annulation of activated α,β-unsaturated ketones with Morita–Baylis–Hillman carbonates: enantioselective synthesis of spirooxindoles containing two adjacent quaternary stereocenters

(2014) Fang-Le Hu et al.   CHEMICAL COMMUNICATIONS

Phosphine catalysis of allenes with electrophiles

(2014) Zhiming Wang et al.   CHEMICAL SOCIETY REVIEWS

Applications of Chiral Phosphine-Based Organocatalysts in Catalytic Asymmetric Reactions

(2014) Yin Wei et al.   Chemistry-An Asian Journal

Catalytic enantioselective synthesis of quaternary carbon stereocentres

(2014) Kyle W. Quasdorf et al.   NATURE

Access to 2′,3′-dihydro-1′H-spiro[indoline-3,4′-pyridin]-2-ones via amino acid derived phosphine-catalyzed asymmetric [4+2] annulation with easily available oxindole-derived α,β-unsaturated imines

(2014) Xiao-Nan Zhang et al.   TETRAHEDRON

Phosphine-Catalyzed Asymmetric [4+2] Annulation of Vinyl Ketones with Oxindole-Derived α,β-Unsaturated Imines: Enantioselective Syntheses of 2′,3′-Dihydro-1′H-spiro[indoline-3,4′-pyridin]-2-ones

(2013) Xiao-Nan Zhang et al.   ADVANCED SYNTHESIS & CATALYSIS

Phosphine-catalyzed [3+2] annulation of α-substituted allenoates with ester-activated α,β-unsaturated imines: a novel variation of the Lu [3+2] cycloaddition reaction

(2013) Junjun Tian et al.   CHEMICAL COMMUNICATIONS

Phosphine-Catalyzed Synthesis of 3,3-Spirocyclopenteneoxindoles from γ-Substituted Allenoates: Systematic Studies and Targeted Applications

(2013) Catherine Gomez et al.   JOURNAL OF ORGANIC CHEMISTRY

Asymmetric Construction of Spirocyclopentenebenzofuranone Core Structures via Highly Selective Phosphine-Catalyzed [3 + 2] Cycloaddition Reactions

(2013) Klaus Albertshofer et al.   ORGANIC LETTERS

Synthesis of 3,3′-Spirocyclic Oxindoles via Phosphine Catalyzed [4 + 2] Cyclizations

(2013) Maxime Gicquel et al.   ORGANIC LETTERS

Phosphine-Catalyzed [4 + 2] Annulation of γ-Substituent Allenoates: Facile Access to Functionalized Spirocyclic Skeletons

(2013) Erqing Li et al.   ORGANIC LETTERS

Phosphine-Catalyzed [3 + 2] Cycloaddition of 4,4-Dicyano-2-methylenebut-3-enoates with Benzyl Buta-2,3-dienoate and Penta-3,4-dien-2-one

(2013) Xiao-Nan Zhang et al.   ACS Catalysis

Heterocyclic Spiranes and Dispiranes via Enantioselective Phosphine-Catalyzed [3+2] Annulations

(2012) Deepti Duvvuru et al.   ADVANCED SYNTHESIS & CATALYSIS

Chiral Phosphine Catalyzed Asymmetric Michael Addition of Oxindoles

(2012) Fangrui Zhong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Synthesis of α-Alkylidene-γ-Butyrolactones: Intramolecular Rauhut-Currier Reaction Promoted by Acid/Base Organocatalysts

(2012) Shinobu Takizawa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Phosphine-catalyzed asymmetric [4+1] annulation of Morita–Baylis–Hillman carbonates with dicyano-2-methylenebut-3-enoates

(2012) Xiao-nan Zhang et al.   CHEMICAL COMMUNICATIONS

Diastereo- and Enantioselective [3 + 2] Cycloaddition Reaction of Morita–Baylis–Hillman Carbonates of Isatins with N-Phenylmaleimide Catalyzed by Me-DuPhos

(2012) Yan Wang et al.   JOURNAL OF ORGANIC CHEMISTRY

Chiral phosphine-catalyzed asymmetric allylic alkylation of 3-substituted benzofuran-2(3H)-ones or oxindoles with Morita–Baylis–Hillman carbonates

(2012) De Wang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

DABCO and Bu3P catalyzed [4 + 2] and [3 + 2] cycloadditions of 3-acyl-2H-chromen-ones and ethyl 2,3-butadienoate

(2012) Ying Wang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Highly enantioselective [4 + 2] cycloadditions of allenoates and dual activated olefins catalyzed by N-acyl aminophosphines

(2012) Hua Xiao et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

BINAPHANE-Catalyzed Asymmetric Synthesis of trans-β-Lactams from Disubstituted Ketenes and N-Tosyl Arylimines

(2012) Shi Chen et al.   ORGANIC LETTERS

Enantioselective synthesis of spirocyclic cyclopentenes: asymmetric [3+2] annulation of 2-arylideneindane-1,3-diones with MBH carbonates derivatives catalyzed by multifunctional thiourea–phosphines

(2012) Fangle Hu et al.   TETRAHEDRON

Facile synthesis of α-methylidene-γ-butyrolactones: intramolecular Rauhut–Currier reaction promoted by chiral acid–base organocatalysts

(2012) Shinobu Takizawa et al.   TETRAHEDRON

Highly enantioselective [4 + 2] annulations catalyzed by amino acid-based phosphines: Synthesis of functionalized cyclohexenes and 3-spirocyclohexene-2-oxindoles

(2012) Fangrui Zhong et al.   Chemical Science

Stereoselective Construction of Quaternary Carbon Stereocenters via a Semipinacol Rearrangement Strategy

(2011) Baomin Wang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Highly Enantioselective [3+2] Annulation of Morita-Baylis-Hillman Adducts Mediated by L-Threonine-Derived Phosphines: Synthesis of 3-Spirocyclopentene-2-oxindoles having Two Contiguous Quaternary Centers

(2011) Fangrui Zhong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Substrate-Controlled, Phosphine-Catalyzed Domino Reactions of Activated Conjugated Dienes: Highly Diastereoselective Synthesis of Bicyclic Skeletons

(2011) Jianze Ma et al.   CHEMISTRY-A EUROPEAN JOURNAL

Phosphine-Catalyzed [4 + 1] Annulation between α,β-Unsaturated Imines and Allylic Carbonates: Synthesis of 2-Pyrrolines

(2011) Junjun Tian et al.   JOURNAL OF ORGANIC CHEMISTRY

Core-Structure-Motivated Design of a Phosphine-Catalyzed [3 + 2] Cycloaddition Reaction: Enantioselective Syntheses of Spirocyclopenteneoxindoles

(2011) Bin Tan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective [3 + 2] Cycloaddition of Allenes to Acrylates Catalyzed by Dipeptide-Derived Phosphines: Facile Creation of Functionalized Cyclopentenes Containing Quaternary Stereogenic Centers

(2011) Xiaoyu Han et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Regio- and Diastereoselective Construction of Spirocyclopenteneoxindoles through Phosphine-Catalyzed [3 + 2] Annulation of Morita–Baylis–Hillman Carbonates with Isatylidene Malononitriles

(2011) Hong-Ping Deng et al.   ORGANIC LETTERS

Phosphine-Catalyzed Cascade [3 + 2] Cyclization−Allylic Alkylation, [2 + 2 + 1] Annulation, and [3 + 2] Cyclization Reactions between Allylic Carbonates and Enones

(2011) Rong Zhou et al.   ORGANIC LETTERS

Tandem cross-Rauhut–Currier/cyclization reactions of activated alkenes to give densely functionalized 3,4-dihydropyrans

(2011) Wen Liu et al.   TETRAHEDRON

Asymmetric [3+2] Cycloadditions of Allenoates and Dual Activated Olefins Catalyzed by Simple Bifunctional N-Acyl Aminophosphines

(2010) Hua Xiao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic enantioselective desymmetrization of cyclic enonesviaphosphine promoted [3+2] annulations

(2010) Nathalie Pinto et al.   CHEMICAL COMMUNICATIONS

Phosphine-catalyzed highly diastereoselective [3+2] cyclization of isatin derived electron-deficient alkenes with α-allenic esters

(2010) Xiu-Chun Zhang et al.   CHEMICAL COMMUNICATIONS

Enantioselective intramolecular Rauhut–Currier reaction catalyzed by chiral phosphinothiourea

(2010) Jing-Jing Gong et al.   CHEMICAL COMMUNICATIONS

An Organocatalytic [3+2] Cyclisation Strategy for the Highly Enantioselective Synthesis of Spirooxindoles

(2010) Arnaud Voituriez et al.   CHEMISTRY-A EUROPEAN JOURNAL

An Unexpected Phosphine-Catalyzed Regio- and Diastereoselective [4+1] Annulation Reaction of Modified Allylic Compounds with Activated Enones

(2010) Zuliang Chen et al.   Chemistry-An Asian Journal

Josiphos-Catalyzed Asymmetric Homodimerization of Ketoketenes

(2010) Ahmad A. Ibrahim et al.   JOURNAL OF ORGANIC CHEMISTRY

2-(Acetoxymethyl)buta-2,3-dienoate, a Versatile 1,4-Biselectrophile for Phosphine-Catalyzed (4 +n) Annulations with 1,n-Bisnucleophiles (n= 1, 2)

(2010) Qiongmei Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Phosphine-Catalyzed Domino Reaction: Highly Stereoselective Synthesis oftrans-2,3-Dihydrobenzofurans from SalicylN-Thiophosphinyl Imines and Allylic Carbonates

(2010) Peizhong Xie et al.   ORGANIC LETTERS

Phosphine-Catalyzed Asymmetric Synthesis of β-Lactones from Arylketoketenes and Aromatic Aldehydes

(2010) Mukulesh Mondal et al.   ORGANIC LETTERS

Enantioselective synthesis of bicarbocyclic structures with an all-carbon quaternary stereocenter through sequential cross metathesis and intramolecular Rauhut–Currier reaction

(2010) Yuan Qiao et al.   TETRAHEDRON LETTERS

Synthesis of Chiral 2-Phospha[3]ferrocenophanes and their Behaviour as Organocatalysts in [3+2] Cyclization Reactions

(2009) Arnaud Voituriez et al.   ADVANCED SYNTHESIS & CATALYSIS

Tertiary Amine Mediated Tandem Cross-Rauhut-Currier/Acetalization Reactions: Access to Functionalized Spiro-3,4-Dihydropyrans

(2009) Weijun Yao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Expanding the Scope of Enantioselective FerroPHANE-Promoted [3+2] Annulations with α,β-Unsaturated Ketones

(2009) Nathalie Pinto et al.   CHEMISTRY-A EUROPEAN JOURNAL

Organocatalytic Dimerization of Ketoketenes

(2009) Ahmad A. Ibrahim et al.   JOURNAL OF ORGANIC CHEMISTRY

Crossed Intramolecular Rauhut−Currier-Type Reactions via Dienamine Activation

(2009) Eugenia Marqués-López et al.   ORGANIC LETTERS

The Rauhut–Currier reaction: a history and its synthetic application

(2009) Carrie E. Aroyan et al.   TETRAHEDRON

Phosphine-triggered synthesis of functionalized cyclic compounds

(2008) Long-Wu Ye et al.   CHEMICAL SOCIETY REVIEWS

2-Phospha[3]ferrocenophanes with Planar Chirality: Synthesis and Use in Enantioselective Organocatalytic [3 + 2] Cyclizations

(2008) Arnaud Voituriez et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY