p63-dependent and independent mechanisms of nectin-1 and nectin-4 regulation in the epidermis

Crosstalk among p53 family members in cutaneous carcinoma

(2014) Caterina Missero et al.   EXPERIMENTAL DERMATOLOGY

Family matters: sibling rivalry and bonding between p53 and p63 in cancer

(2014) Rose-Anne Romano et al.   EXPERIMENTAL DERMATOLOGY

Nectin-4 Mutations Causing Ectodermal Dysplasia with Syndactyly Perturb the Rac1 Pathway and the Kinetics of Adherens Junction Formation

(2014) Paola Fortugno et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Rapid and Pervasive Changes in Genome-wide Enhancer Usage during Mammalian Development

(2013) Alex S. Nord et al.   CELL

Expansion of epidermal progenitors with high p63 phosphorylation during wound healing of mouse epidermis

(2013) Daisuke Suzuki et al.   EXPERIMENTAL DERMATOLOGY

Mutations in AEC syndrome skin reveal a role for p63 in basement membrane adhesion, skin barrier integrity and hair follicle biology

(2012) S.E. Clements et al.   BRITISH JOURNAL OF DERMATOLOGY

 Np63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiation

(2012) R.-A. Romano et al.   DEVELOPMENT

Mutant p63 causes defective expansion of ectodermal progenitor cells and impaired FGF signalling in AEC syndrome

(2012) Giustina Ferone et al.   EMBO Molecular Medicine

p63 control of desmosome gene expression and adhesion is compromised in AEC syndrome

(2012) Giustina Ferone et al.   HUMAN MOLECULAR GENETICS

The role of nectins in different types of cell-cell adhesion

(2012) Y. Rikitake et al.   JOURNAL OF CELL SCIENCE

Genome-wide analysis of p63 binding sites identifies AP-2 factors as co-regulators of epidermal differentiation

(2012) Simon S. McDade et al.   NUCLEIC ACIDS RESEARCH

IRF6 is a mediator of Notch pro-differentiation and tumour suppressive function in keratinocytes

(2011) Gaetana Restivo et al.   EMBO JOURNAL

Mutation in PVRL4 gene encoding nectin-4 underlies ectodermal-dysplasia-syndactyly syndrome (EDSS1)

(2011) Musharraf Jelani et al.   JOURNAL OF HUMAN GENETICS

Mapping and analysis of chromatin state dynamics in nine human cell types

(2011) Jason Ernst et al.   NATURE

Mutations in PVRL4, Encoding Cell Adhesion Molecule Nectin-4, Cause Ectodermal Dysplasia-Syndactyly Syndrome

(2010) Francesco Brancati et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Cooperation between the transcription factors p63 and IRF6 is essential to prevent cleft palate in mice

(2010) Helen A. Thomason et al.   JOURNAL OF CLINICAL INVESTIGATION

A regulatory feedback loop involving p63 and IRF6 links the pathogenesis of 2 genetically different human ectodermal dysplasias

(2010) Francesca Moretti et al.   JOURNAL OF CLINICAL INVESTIGATION

Transcriptional Repression of miR-34 Family Contributes to p63-Mediated Cell Cycle Progression in Epidermal Cells

(2010) Dario Antonini et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

A unique chromatin signature uncovers early developmental enhancers in humans

(2010) Alvaro Rada-Iglesias et al.   NATURE

Adherens junctions: from molecules to morphogenesis

(2010) Tony J. C. Harris et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Histone H3K27ac separates active from poised enhancers and predicts developmental state

(2010) M. P. Creyghton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-Wide Profiling of p63 DNA–Binding Sites Identifies an Element that Regulates Gene Expression during Limb Development in the 7q21 SHFM1 Locus

(2010) Evelyn N. Kouwenhoven et al.   PLoS Genetics

Spectrum ofp63mutations in a selected patient cohort affected with ankyloblepharon-ectodermal defects-cleft lip/palate syndrome (AEC)

(2009) Tuula Rinne et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

p63 Suppresses Non-epidermal Lineage Markers in a Bone Morphogenetic Protein-dependent Manner via Repression of Smad7

(2009) Laura De Rosa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adherens Junction: Molecular Architecture and Regulation

(2009) W. Meng et al.   Cold Spring Harbor Perspectives in Biology

P-cadherin is a p63 target gene with a crucial role in the developing human limb bud and hair follicle

(2008) Y. Shimomura et al.   DEVELOPMENT

A novel translation re-initiation mechanism for the p63 gene revealed by amino-terminal truncating mutations in Rapp-Hodgkin/Hay-Wells-like syndromes

(2008) T. Rinne et al.   HUMAN MOLECULAR GENETICS

The cell adhesion molecule nectin-1 is critical for normal enamel formation in mice

(2008) Martin J. Barron et al.   HUMAN MOLECULAR GENETICS

Claudin-1 Is a p63 Target Gene with a Crucial Role in Epithelial Development

(2008) Teresa Lopardo et al.   PLoS One

New insights into cadherin function in epidermal sheet formation and maintenance of tissue integrity

(2008) C. L. Tinkle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA