Cooperation between the transcription factors p63 and IRF6 is essential to prevent cleft palate in mice

A regulatory feedback loop involving p63 and IRF6 links the pathogenesis of 2 genetically different human ectodermal dysplasias

(2010) Francesca Moretti et al.   JOURNAL OF CLINICAL INVESTIGATION

The α/β carboxy-terminal domains of p63 are required for skin and limb development. New insights from the Brdm2 mouse which is not a complete p63 knockout but expresses p63 γ-like proteins

(2009) S Wolff et al.   CELL DEATH AND DIFFERENTIATION

Prevalence and nonrandom distribution of exonic mutations in interferon regulatory factor 6 in 307 families with Van der Woude syndrome and 37 families with popliteal pterygium syndrome

(2009) Renata L L Ferreira de Lima et al.   GENETICS IN MEDICINE

Integration of IRF6 and Jagged2 signalling is essential for controlling palatal adhesion and fusion competence

(2009) Rebecca J. Richardson et al.   HUMAN MOLECULAR GENETICS

An Active Role of the ΔN Isoform of p63 in Regulating Basal Keratin Genes K5 and K14 and Directing Epidermal Cell Fate

(2009) Rose-Anne Romano et al.   PLoS One

TFAP2A Mutations Result in Branchio-Oculo-Facial Syndrome

(2008) Jeff M. Milunsky et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Mouse genetic models of cleft lip with or without cleft palate

(2008) Diana M. Juriloff et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Facial clefting in Tp63 deficient mice results from altered Bmp4, Fgf8 and Shh signaling

(2008) Helen A. Thomason et al.   DEVELOPMENTAL BIOLOGY

Genome-wide profiling of PPAR :RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during adipogenesis

(2008) R. Nielsen et al.   GENES & DEVELOPMENT

Interferon Regulatory Factor 6 Promotes Cell Cycle Arrest and Is Regulated by the Proteasome in a Cell Cycle-Dependent Manner

(2008) C. M. Bailey et al.   MOLECULAR AND CELLULAR BIOLOGY

Disruption of an AP-2α binding site in an IRF6 enhancer is associated with cleft lip

(2008) Fedik Rahimov et al.   NATURE GENETICS

Characterization of genome-wide p53-binding sites upon stress response

(2008) Leonie Smeenk et al.   NUCLEIC ACIDS RESEARCH

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY