IRF6 is a mediator of Notch pro-differentiation and tumour suppressive function in keratinocytes

A Role for the Primary Cilium in Notch Signaling and Epidermal Differentiation during Skin Development

(2011) Ellen J. Ezratty et al.   CELL

IRF6 in development and disease: A mediator of quiescence and differentiation

(2011) Caleb M. Bailey et al.   CELL CYCLE

Asymmetric cell divisions promote Notch-dependent epidermal differentiation

(2011) Scott E. Williams et al.   NATURE

Antagonistic roles of Notch and p63 in controlling mammary epithelial cell fates

(2010) Ö Yalcin-Ozuysal et al.   CELL DEATH AND DIFFERENTIATION

Adult epidermal Notch activity induces dermal accumulation of T cells and neural crest derivatives through upregulation of jagged 1

(2010) C. A. Ambler et al.   DEVELOPMENT

Cooperation between the transcription factors p63 and IRF6 is essential to prevent cleft palate in mice

(2010) Helen A. Thomason et al.   JOURNAL OF CLINICAL INVESTIGATION

A regulatory feedback loop involving p63 and IRF6 links the pathogenesis of 2 genetically different human ectodermal dysplasias

(2010) Francesca Moretti et al.   JOURNAL OF CLINICAL INVESTIGATION

Opposing roles for calcineurin and ATF3 in squamous skin cancer

(2010) Xunwei Wu et al.   NATURE

Atopic Dermatitis-Like Disease and Associated Lethal Myeloproliferative Disorder Arise from Loss of Notch Signaling in the Murine Skin

(2010) Alexis Dumortier et al.   PLoS One

Dose-dependent induction of distinct phenotypic responses to Notch pathway activation in mammary epithelial cells

(2010) M. Mazzone et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism

(2009) Raphael Kopan et al.   CELL

Pre-TCR signaling inactivates Notch1 transcription by antagonizing E2A

(2009) Y. Yashiro-Ohtani et al.   GENES & DEVELOPMENT

Integration of IRF6 and Jagged2 signalling is essential for controlling palatal adhesion and fusion competence

(2009) Rebecca J. Richardson et al.   HUMAN MOLECULAR GENETICS

A positive FGFR3/FOXN1 feedback loop underlies benign skin keratosis versus squamous cell carcinoma formation in humans

(2009) Anna Mandinova et al.   JOURNAL OF CLINICAL INVESTIGATION

Skin-Derived TSLP Triggers Progression from Epidermal-Barrier Defects to Asthma

(2009) Shadmehr Demehri et al.   PLOS BIOLOGY

The IRF Family Transcription Factors in Immunity and Oncogenesis

(2008) Tomohiko Tamura et al.   Annual Review of Immunology

Epidermal Notch signalling: differentiation, cancer and adhesion

(2008) Fiona M Watt et al.   CURRENT OPINION IN CELL BIOLOGY

Global analysis of the insulator binding protein CTCF in chromatin barrier regions reveals demarcation of active and repressive domains

(2008) S. Cuddapah et al.   GENOME RESEARCH

AP-2 factors act in concert with Notch to orchestrate terminal differentiation in skin epidermis

(2008) Xuan Wang et al.   JOURNAL OF CELL BIOLOGY

Interferon Regulatory Factor 6 Promotes Cell Cycle Arrest and Is Regulated by the Proteasome in a Cell Cycle-Dependent Manner

(2008) C. M. Bailey et al.   MOLECULAR AND CELLULAR BIOLOGY

EGFR signalling as a negative regulator of Notch1 gene transcription and function in proliferating keratinocytes and cancer

(2008) Vihren Kolev et al.   NATURE CELL BIOLOGY

Disruption of an AP-2α binding site in an IRF6 enhancer is associated with cleft lip

(2008) Fedik Rahimov et al.   NATURE GENETICS

Rational targeting of Notch signaling in cancer

(2008) P Rizzo et al.   ONCOGENE

Notch tumor suppressor function

(2008) G P Dotto   ONCOGENE

Role of the Notch Ligand Delta1 in Embryonic and Adult Mouse Epidermis

(2007) Soline Estrach et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY