Fructose: A Dietary Sugar in Crosstalk with Microbiota Contributing to the Development and Progression of Non-Alcoholic Liver Disease

Protective effect of quercetin on high-fat diet-induced non-alcoholic fatty liver disease in mice is mediated by modulating intestinal microbiota imbalance and related gut-liver axis activation

(2017) David Porras et al.   FREE RADICAL BIOLOGY AND MEDICINE

A gut reaction: the combined influence of exercise and diet on gastrointestinal microbiota in rats

(2017) R.B. Batacan et al.   JOURNAL OF APPLIED MICROBIOLOGY

Intestinal Barrier Function and the Gut Microbiome Are Differentially Affected in Mice Fed a Western-Style Diet or Drinking Water Supplemented with Fructose

(2017) Valentina Volynets et al.   JOURNAL OF NUTRITION

The Mediterranean dietary pattern as the diet of choice for non-alcoholic fatty liver disease: Evidence and plausible mechanisms

(2017) Shira Zelber-Sagi et al.   LIVER INTERNATIONAL

Non-alcoholic fatty liver disease: An update with special focus on the role of gut microbiota

(2017) Michael Doulberis et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

A synbiotic composed of Lactobacillus fermentum CECT5716 and FOS prevents the development of fatty acid liver and glycemic alterations in rats fed a high fructose diet associated with changes in the microbiota

(2017) Belén Rivero-Gutiérrez et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Diet-driven microbiota dysbiosis is associated with vagal remodeling and obesity

(2017) Tanusree Sen et al.   PHYSIOLOGY & BEHAVIOR

Sodium butyrate attenuates high-fat diet-induced steatohepatitis in mice by improving gut microbiota and gastrointestinal barrier

(2017) Da Zhou et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Inborn Errors of Fructose Metabolism. What Can We Learn from Them?

(2017) Christel Tran   Nutrients

Fructose Intake, Serum Uric Acid, and Cardiometabolic Disorders: A Critical Review

(2017) Cristiana Caliceti et al.   Nutrients

Probiotics may delay the progression of nonalcoholic fatty liver disease by restoring the gut microbiota structure and improving intestinal endotoxemia

(2017) Li Xue et al.   Scientific Reports

Dietary fructose causes defective insulin signalling and ceramide accumulation in the liver that can be reversed by gut microbiota modulation

(2017) Raffaella Crescenzo et al.   Food & Nutrition Research

Gut Microbiota Modulation and Its Relationship with Obesity Using Prebiotic Fibers and Probiotics: A Review

(2017) Dinesh K. Dahiya et al.   Frontiers in Microbiology

Differences in Gut Metabolites and Microbial Composition and Functions between Egyptian and U.S. Children Are Consistent with Their Diets

(2017) V. Shankar et al.   mSystems

Recent progress in the identification of adenosine monophosphate-activated protein kinase (AMPK) activators

(2016) Kimberly O. Cameron et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Preventive effects of citrulline on Western diet-induced non-alcoholic fatty liver disease in rats

(2016) Prasanthi Jegatheesan et al.   BRITISH JOURNAL OF NUTRITION

From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites

(2016) Ara Koh et al.   CELL

Effect of specific amino acids on hepatic lipid metabolism in fructose-induced non-alcoholic fatty liver disease

(2016) Prasanthi Jegatheesan et al.   CLINICAL NUTRITION

Antidiabetic effect of enterolactone in cultured muscle cells and in type 2 diabetic model db/db mice

(2016) Fang Zhou et al.   CYTOTECHNOLOGY

Pathophysiology of Nonalcoholic Fatty Liver Disease: Lifestyle-Gut-Gene Interaction

(2016) Arianna Mazzotti et al.   DIGESTIVE DISEASES

Pediatric obesity is associated with an altered gut microbiota and discordant shifts inFirmicutespopulations

(2016) Alessandra Riva et al.   ENVIRONMENTAL MICROBIOLOGY

Loss of Junctional Adhesion Molecule A Promotes Severe Steatohepatitis in Mice on a Diet High in Saturated Fat, Fructose, and Cholesterol

(2016) Khalidur Rahman et al.   GASTROENTEROLOGY

Effect of uric acid on mitochondrial function and oxidative stress in hepatocytes

(2016) Y. Yang et al.   GENETICS AND MOLECULAR RESEARCH

Gut Microbiota and Lifestyle Interventions in NAFLD

(2016) David Houghton et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Non-alcoholic fatty liver disease and cardiovascular risk: Pathophysiological mechanisms and implications

(2016) Sven M. Francque et al.   JOURNAL OF HEPATOLOGY

Early-Life Sugar Consumption Affects the Rat Microbiome Independently of Obesity

(2016) Emily E Noble et al.   JOURNAL OF NUTRITION

Table grape consumption reduces adiposity and markers of hepatic lipogenesis and alters gut microbiota in butter fat-fed mice

(2016) Jessie Baldwin et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Probiotics in Childhood Diseases

(2016) Alfredo Guarino et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Activation of Kupffer Cells Is Associated with a Specific Dysbiosis Induced by Fructose or High Fat Diet in Mice

(2016) Gladys Ferrere et al.   PLoS One

The Intestinal Microbiota in Metabolic Disease

(2016) Anni Woting et al.   Nutrients

Natural Polyphenols for Prevention and Treatment of Cancer

(2016) Yue Zhou et al.   Nutrients

Impact of the gut microbiota on inflammation, obesity, and metabolic disease

(2016) Claire L. Boulangé et al.   Genome Medicine

Exercise-Induced Release of Pharmacologically Active Substances and Their Relevance for Therapy of Hepatic Injury

(2016) Hans-Theo Schon et al.   Frontiers in Pharmacology

Progressive Induction of Type 2 Diabetes: Effects of a Reality–Like Fructose Enriched Diet in Young Wistar Rats

(2016) Julie Dupas et al.   PLoS One

Intestinal Microbiota And Diet in IBS: Causes, Consequences, or Epiphenomena?

(2015) Mirjana Rajilić-Stojanović et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Akkermansia muciniphila Adheres to Enterocytes and Strengthens the Integrity of the Epithelial Cell Layer

(2015) Justus Reunanen et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Lactobacillus paracasei Induces M2-Dominant Kupffer Cell Polarization in a Mouse Model of Nonalcoholic Steatohepatitis

(2015) Won Sohn et al.   DIGESTIVE DISEASES AND SCIENCES

Diets rich in fructose, fat or fructose and fat alter intestinal barrier function and lead to the development of nonalcoholic fatty liver disease over time

(2015) Cathrin Sellmann et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Effects of Dietary Different Doses of Copper and High Fructose Feeding on Rat Fecal Metabolome

(2015) Xiaoli Wei et al.   JOURNAL OF PROTEOME RESEARCH

Short-chain fatty acids in control of body weight and insulin sensitivity

(2015) Emanuel E. Canfora et al.   Nature Reviews Endocrinology

NGL Viewer: a web application for molecular visualization

(2015) Alexander S. Rose et al.   NUCLEIC ACIDS RESEARCH

Dietary Gut Microbial Metabolites, Short-chain Fatty Acids, and Host Metabolic Regulation

(2015) Mayu Kasubuchi et al.   Nutrients

Rescue of Fructose-Induced Metabolic Syndrome by Antibiotics or Faecal Transplantation in a Rat Model of Obesity

(2015) Blanda Di Luccia et al.   PLoS One

High uric acid directly inhibits insulin signalling and induces insulin resistance

(2014) Yuzhang Zhu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Dietary sugars: their detection by the gut–brain axis and their peripheral and central effects in health and diseases

(2014) Melissa Ochoa et al.   EUROPEAN JOURNAL OF NUTRITION

Uric acid induces fat accumulation via generation of endoplasmic reticulum stress and SREBP-1c activation in hepatocytes

(2014) Yea-Jin Choi et al.   LABORATORY INVESTIGATION

Lactobacillus rhamnosus GG Protects against Non-Alcoholic Fatty Liver Disease in Mice

(2014) Yvonne Ritze et al.   PLoS One

The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism

(2014) Gary Frost et al.   Nature Communications

Unclear Abdominal Discomfort: Pivotal Role of Carbohydrate Malabsorption

(2014) Miriam Goebel-Stengel et al.   Journal of Neurogastroenterology and Motility

Symptomatic fructose malabsorption in irritable bowel syndrome: A prospective study

(2014) Chloé Melchior et al.   United European Gastroenterology Journal

Dietary fructose induces endotoxemia and hepatic injury in calorically controlled primates

(2013) Kylie Kavanagh et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Gut-derived short-chain fatty acids are vividly assimilated into host carbohydrates and lipids

(2013) Gijs den Besten et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Intestinal colonization: How key microbial players become established in this dynamic process

(2013) Sahar El Aidy et al.   BIOESSAYS

Fecal Microbiome and Volatile Organic Compound Metabolome in Obese Humans With Nonalcoholic Fatty Liver Disease

(2013) Maitreyi Raman et al.   Clinical Gastroenterology and Hepatology

Intestinal microbiota in patients with nonalcoholic fatty liver disease

(2013) Marialena Mouzaki et al.   HEPATOLOGY

Dysbiosis contributes to fibrogenesis in the course of chronic liver injury in mice

(2013) Samuele De Minicis et al.   HEPATOLOGY

The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism

(2013) Gijs den Besten et al.   JOURNAL OF LIPID RESEARCH

Butyrate-Producing Probiotics Reduce Nonalcoholic Fatty Liver Disease Progression in Rats: New Insight into the Probiotics for the Gut-Liver Axis

(2013) Hitoshi Endo et al.   PLoS One

Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity

(2013) A. Everard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dual probiotic strains suppress high fructose-induced metabolic syndrome

(2013) Do-Young Park   WORLD JOURNAL OF GASTROENTEROLOGY

Challenging the Fructose Hypothesis: New Perspectives on Fructose Consumption and Metabolism

(2013) John S. White   Advances in Nutrition

Uric Acid Induces Hepatic Steatosis by Generation of Mitochondrial Oxidative Stress

(2012) Miguel A. Lanaspa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Role of Nutrients in the Development, Progression, and Treatment of Nonalcoholic Fatty Liver Disease

(2012) Marialena Mouzaki et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Lactobacillus casei Shirota protects from fructose-induced liver steatosis: A mouse model

(2012) Sabine Wagnerberger et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Metformin protects against the development of fructose-induced steatosis in mice: role of the intestinal barrier function

(2012) Astrid Spruss et al.   LABORATORY INVESTIGATION

High Fat Diet-Induced Gut Microbiota Exacerbates Inflammation and Obesity in Mice via the TLR4 Signaling Pathway

(2012) Kyung-Ah Kim et al.   PLoS One

Toll-like receptors 1–9 are elevated in livers with fructose-induced hepatic steatosis

(2011) Sabine Wagnerberger et al.   BRITISH JOURNAL OF NUTRITION

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

(2011) Zeneng Wang et al.   NATURE

Protective effects of Lactobacillus paracasei F19 in a rat model of oxidative and metabolic hepatic injury

(2010) Gerardo Nardone et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

From the metabolic syndrome to NAFLD or vice versa?

(2010) Ester Vanni et al.   DIGESTIVE AND LIVER DISEASE

Short-Chain Fatty Acids Regulate the Enteric Neurons and Control Gastrointestinal Motility in Rats

(2010) Rodolphe Soret et al.   GASTROENTEROLOGY

A position statement on NAFLD/NASH based on the EASL 2009 special conference

(2010) Vlad Ratziu et al.   JOURNAL OF HEPATOLOGY

Protective effect of bile acids on the onset of fructose-induced hepatic steatosis in mice

(2010) Valentina Volynets et al.   JOURNAL OF LIPID RESEARCH

From the gut to the peripheral tissues: the multiple effects of butyrate

(2010) P. Guilloteau et al.   NUTRITION RESEARCH REVIEWS

The role of pH in determining the species composition of the human colonic microbiota

(2009) Sylvia H. Duncan et al.   ENVIRONMENTAL MICROBIOLOGY

Butyrate Enhances the Intestinal Barrier by Facilitating Tight Junction Assembly via Activation of AMP-Activated Protein Kinase in Caco-2 Cell Monolayers

(2009) Luying Peng et al.   JOURNAL OF NUTRITION

Dietary fructose and intestinal barrier: potential risk factor in the pathogenesis of nonalcoholic fatty liver disease

(2009) Astrid Spruss et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The Effect of Diet on the Human Gut Microbiome: A Metagenomic Analysis in Humanized Gnotobiotic Mice

(2009) P. J. Turnbaugh et al.   Science Translational Medicine

Diet-Induced Obesity Is Linked to Marked but Reversible Alterations in the Mouse Distal Gut Microbiome

(2008) Peter J. Turnbaugh et al.   Cell Host & Microbe

Antibiotics protect against fructose-induced hepatic lipid accumulation in mice: Role of endotoxin

(2008) Ina Bergheim et al.   JOURNAL OF HEPATOLOGY

Non-alcoholic fatty liver disease: The mist gradually clears

(2008) Nimantha Mark Wilfred de Alwis et al.   JOURNAL OF HEPATOLOGY

Short-chain fatty acids and trichostatin A alter tight junction permeability in human umbilical vein endothelial cells

(2008) Makoto Miyoshi et al.   NUTRITION

Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41

(2008) B. S. Samuel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fatty Liver

(2007) Anna Kotronen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY