Uric acid induces fat accumulation via generation of endoplasmic reticulum stress and SREBP-1c activation in hepatocytes

Ablation of Ceramide Synthase 2 Causes Chronic Oxidative Stress Due to Disruption of the Mitochondrial Respiratory Chain

(2013) Hila Zigdon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endoplasmic Reticulum Stress in Nonalcoholic Fatty Liver Disease

(2012) Michael J. Pagliassotti   Annual Review of Nutrition

Ablation of very long acyl chain sphingolipids causes hepatic insulin resistance in mice due to altered detergent-resistant membranes

(2012) Joo-Won Park et al.   HEPATOLOGY

Uric Acid Induces Hepatic Steatosis by Generation of Mitochondrial Oxidative Stress

(2012) Miguel A. Lanaspa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Elevated serum uric acid levels are associated with non-alcoholic fatty liver disease independently of metabolic syndrome features in the United States: Liver ultrasound data from the National Health and Nutrition Examination Survey

(2012) Jeffrey C. Sirota et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Uric Acid Stimulates Fructokinase and Accelerates Fructose Metabolism in the Development of Fatty Liver

(2012) Miguel A. Lanaspa et al.   PLoS One

Endoplasmic reticulum stress is involved in hepatic SREBP-1c activation and lipid accumulation in fructose-fed mice

(2012) Cheng Zhang et al.   TOXICOLOGY LETTERS

AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-Induced Insulin-Resistant Mice

(2011) Yu Li et al.   Cell Metabolism

Cross talk between mitochondria and NADPH oxidases

(2011) Sergey Dikalov   FREE RADICAL BIOLOGY AND MEDICINE

Hypouricemic therapy: A novel potential therapeutic option for nonalcoholic fatty liver disease

(2010) Cheng-Fu Xu et al.   HEPATOLOGY

Mitochondrial dysfunction precedes insulin resistance and hepatic steatosis and contributes to the natural history of non-alcoholic fatty liver disease in an obese rodent model

(2010) R. Scott Rector et al.   JOURNAL OF HEPATOLOGY

Serum uric acid levels predict incident nonalcoholic fatty liver disease in healthy Korean men

(2010) Seungho Ryu et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Changes in Hepatic Gene Expression upon Oral Administration of Taurine-Conjugated Ursodeoxycholic Acid in ob/ob Mice

(2010) Jae-Seong Yang et al.   PLoS One

Dephosphorylation of Translation Initiation Factor 2α Enhances Glucose Tolerance and Attenuates Hepatosteatosis in Mice

(2008) Seiichi Oyadomari et al.   Cell Metabolism

Recent advances in nonalcholic fatty liver disease

(2008) Victoria Greenfield et al.   CURRENT OPINION IN GASTROENTEROLOGY

UPR Pathways Combine to Prevent Hepatic Steatosis Caused by ER Stress-Mediated Suppression of Transcriptional Master Regulators

(2008) D. Thomas Rutkowski et al.   DEVELOPMENTAL CELL

Regulation of Hepatic Lipogenesis by the Transcription Factor XBP1

(2008) A.-H. Lee et al.   SCIENCE