标题
Ubiquitination in melanoma pathogenesis and treatment
作者
关键词
-
出版物
Cancer Medicine
Volume 6, Issue 6, Pages 1362-1377
出版商
Wiley
发表日期
2017-05-24
DOI
10.1002/cam4.1069
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Development of a Novel Experimental In Vitro Model of Isothiocyanate-induced Apoptosis in Human Malignant Melanoma Cells
- (2016) THEODORA MANTSO et al. ANTICANCER RESEARCH
- Targeting the protein ubiquitination machinery in melanoma by the NEDD8-activating enzyme inhibitor pevonedistat (MLN4924)
- (2016) Kit Man Wong et al. INVESTIGATIONAL NEW DRUGS
- A phase I study of the investigational NEDD8-activating enzyme inhibitor pevonedistat (TAK-924/MLN4924) in patients with metastatic melanoma
- (2016) Shailender Bhatia et al. INVESTIGATIONAL NEW DRUGS
- Parkin Somatic Mutations Link Melanoma and Parkinson's Disease
- (2016) Lotan Levin et al. Journal of Genetics and Genomics
- Mechanistic validation of a clinical lead stapled peptide that reactivates p53 by dual HDM2 and HDMX targeting
- (2016) F Wachter et al. ONCOGENE
- Downregulation of sphingosine kinase-1 induces protective tumor immunity by promoting M1 macrophage response in melanoma
- (2016) Marguerite Mrad et al. Oncotarget
- Clinical Overview of MDM2/X-Targeted Therapies
- (2016) Andrew Burgess et al. Frontiers in Oncology
- Cancer statistics, 2015
- (2015) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Naturally Occurring Isothiocyanates Exert Anticancer Effects by Inhibiting Deubiquitinating Enzymes
- (2015) A. P. Lawson et al. CANCER RESEARCH
- RIP1 Kinase Is an Oncogenic Driver in Melanoma
- (2015) X. Y. Liu et al. CANCER RESEARCH
- BAP1 and BRAFV600E expression in benign and malignant melanocytic proliferations
- (2015) Adriano Piris et al. HUMAN PATHOLOGY
- BAP1 Has a Survival Role in Cutaneous Melanoma
- (2015) Raj Kumar et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- PARKINInactivation Links Parkinson’s Disease to Melanoma
- (2015) Hui-Han Hu et al. JNCI-Journal of the National Cancer Institute
- Dabrafenib and trametinib versus dabrafenib and placebo for Val600 BRAF-mutant melanoma: a multicentre, double-blind, phase 3 randomised controlled trial
- (2015) Georgina V Long et al. LANCET
- E3 ubiquitin ligases as drug targets and prognostic biomarkers in melanoma
- (2015) Kristina Bielskienė et al. Medicina-Lithuania
- PARKINInactivation Links Parkinson’s Disease to Melanoma
- (2015) Hui-Han Hu et al. JNCI-Journal of the National Cancer Institute
- E3 ubiquitin ligases as drug targets and prognostic biomarkers in melanoma
- (2015) Kristina Bielskienė et al. Medicina-Lithuania
- Tumor Suppression by the Fbw7 Ubiquitin Ligase: Mechanisms and Opportunities
- (2014) Ryan J. Davis et al. CANCER CELL
- The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells
- (2014) Magdalena Paolino et al. NATURE
- USP15 stabilizes MDM2 to mediate cancer-cell survival and inhibit antitumor T cell responses
- (2014) Qiang Zou et al. NATURE IMMUNOLOGY
- Ubiquitination in disease pathogenesis and treatment
- (2014) Doris Popovic et al. NATURE MEDICINE
- The melanoma revolution: From UV carcinogenesis to a new era in therapeutics
- (2014) J. A. Lo et al. SCIENCE
- Beclin 1 restrains tumorigenesis through Mcl-1 destabilization in an autophagy-independent reciprocal manner
- (2014) Mohamed Elgendy et al. Nature Communications
- Restoring p53 Function in Human Melanoma Cells by Inhibiting MDM2 and Cyclin B1/CDK1-Phosphorylated Nuclear iASPP
- (2013) Min Lu et al. CANCER CELL
- Cullin-RING Ligases as Attractive Anti-cancer Targets
- (2013) Yongchao Zhao et al. CURRENT PHARMACEUTICAL DESIGN
- Activin receptor-like kinase5 inhibition suppresses mouse melanoma by ubiquitin degradation of Smad4, thereby derepressing eomesodermin in cytotoxic T lymphocytes
- (2013) Jeong-Hwan Yoon et al. EMBO Molecular Medicine
- Prognostic Significance of Fbw7 in Human Melanoma and Its Role in Cell Migration
- (2013) Yabin Cheng et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- A Signal Transduction Pathway from TGF-β1 to SKP2 via Akt1 and c-Myc and its Correlation with Progression in Human Melanoma
- (2013) Xuan Qu et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Cutaneous melanoma
- (2013) Alexander MM Eggermont et al. LANCET
- The FBXO4 Tumor Suppressor Functions as a Barrier to BrafV600E-Dependent Metastatic Melanoma
- (2013) Eric K. Lee et al. MOLECULAR AND CELLULAR BIOLOGY
- Safety and Tumor Responses with Lambrolizumab (Anti–PD-1) in Melanoma
- (2013) Omid Hamid et al. NEW ENGLAND JOURNAL OF MEDICINE
- The Discovery of a Reciprocal Relationship between Tyrosine-Kinase Signaling and Cullin Neddylation
- (2013) Samantha F. Friend et al. PLoS One
- Stapled α−helical peptide drug development: A potent dual inhibitor of MDM2 and MDMX for p53-dependent cancer therapy
- (2013) Yong S. Chang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Ubiquitin Code
- (2012) David Komander et al. Annual Review of Biochemistry
- Novel DNA Damage Checkpoints Mediating Cell Death Induced by the NEDD8-Activating Enzyme Inhibitor MLN4924
- (2012) J. L. Blank et al. CANCER RESEARCH
- A Landscape of Driver Mutations in Melanoma
- (2012) Eran Hodis et al. CELL
- Tumor suppressor functions of FBW7 in cancer development and progression
- (2012) Zhiwei Wang et al. FEBS LETTERS
- Melanoma: from mutations to medicine
- (2012) H. Tsao et al. GENES & DEVELOPMENT
- Dabrafenib in BRAF-mutated metastatic melanoma: a multicentre, open-label, phase 3 randomised controlled trial
- (2012) Axel Hauschild et al. LANCET
- Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma
- (2012) Michael Krauthammer et al. NATURE GENETICS
- Improved Survival with MEK Inhibition in BRAF-Mutated Melanoma
- (2012) Keith T. Flaherty et al. NEW ENGLAND JOURNAL OF MEDICINE
- Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer
- (2012) Suzanne L. Topalian et al. NEW ENGLAND JOURNAL OF MEDICINE
- Neddylation pathway regulates T-cell function by targeting an adaptor protein Shc and a protein kinase Erk signaling
- (2012) H.-s. Jin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A novel role for RIP1 kinase in mediating TNFα production
- (2012) D E Christofferson et al. Cell Death & Disease
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- LUBAC regulates NF-κB activation upon genotoxic stress by promoting linear ubiquitination of NEMO
- (2011) Jixiao Niu et al. EMBO JOURNAL
- USP13 Enzyme Regulates Siah2 Ligase Stability and Activity via Noncatalytic Ubiquitin-binding Domains
- (2011) Marzia Scortegagna et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inhibition of Human Melanoma Cell Growth by the Dietary Flavonoid Fisetin Is Associated with Disruption of Wnt/β-Catenin Signaling and Decreased Mitf Levels
- (2011) Deeba N. Syed et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Homology modeling and in silico screening of inhibitors for the substrate binding domain of human Siah2: implications for hypoxia-induced cancers
- (2011) Gopalsamy Anupriya et al. JOURNAL OF MOLECULAR MODELING
- Systematic and Quantitative Assessment of the Ubiquitin-Modified Proteome
- (2011) Woong Kim et al. MOLECULAR CELL
- A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma
- (2011) Satoru Yokoyama et al. NATURE
- A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma
- (2011) Corine Bertolotto et al. NATURE
- Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing
- (2011) Mitchell S Stark et al. NATURE GENETICS
- Germline mutations in BAP1 predispose to melanocytic tumors
- (2011) Thomas Wiesner et al. NATURE GENETICS
- The spatial and temporal organization of ubiquitin networks
- (2011) Caroline Grabbe et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Meta-analysis of the relationship between Parkinson disease and melanoma
- (2011) R. Liu et al. NEUROLOGY
- Improved Survival with Vemurafenib in Melanoma with BRAF V600E Mutation
- (2011) Paul B. Chapman et al. NEW ENGLAND JOURNAL OF MEDICINE
- Cytoplasmic Skp2 Expression Is Increased in Human Melanoma and Correlated with Patient Survival
- (2011) Guangdi Chen et al. PLoS One
- Ripoptosome: a novel IAP-regulated cell death-signalling platform
- (2011) G. Imre et al. Journal of Molecular Cell Biology
- Regulation of MITF stability by the USP13 deubiquitinase
- (2011) Xiansi Zhao et al. Nature Communications
- Ink4a/Arf and Oncogene-Induced Senescence Prevent Tumor Progression during Alternative Colorectal Tumorigenesis
- (2010) Moritz Bennecke et al. CANCER CELL
- Ubiquitin networks in cancer
- (2010) Vladimir Kirkin et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Contrasting Effects of Nutlin-3 on TRAIL- and Docetaxel-Induced Apoptosis Due to Upregulation of TRAIL-R2 and Mcl-1 in Human Melanoma Cells
- (2010) H.-Y. Tseng et al. MOLECULAR CANCER THERAPEUTICS
- K11-Linked Polyubiquitination in Cell Cycle Control Revealed by a K11 Linkage-Specific Antibody
- (2010) Marissa L. Matsumoto et al. MOLECULAR CELL
- Global analysis of lysine ubiquitination by ubiquitin remnant immunoaffinity profiling
- (2010) Guoqiang Xu et al. NATURE BIOTECHNOLOGY
- Inhibition of Mutated, Activated BRAF in Metastatic Melanoma
- (2010) Keith T. Flaherty et al. NEW ENGLAND JOURNAL OF MEDICINE
- Improved Survival with Ipilimumab in Patients with Metastatic Melanoma
- (2010) F. Stephen Hodi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Growth and progression of melanoma and non-melanoma skin cancers regulated by ubiquitination
- (2010) Koh Nakayama Pigment Cell & Melanoma Research
- Frequent Mutation of BAP1 in Metastasizing Uveal Melanomas
- (2010) J. W. Harbour et al. SCIENCE
- Regulation and Cellular Roles of Ubiquitin-Specific Deubiquitinating Enzymes
- (2009) Francisca E. Reyes-Turcu et al. Annual Review of Biochemistry
- Oncogenic Braf Induces Melanocyte Senescence and Melanoma in Mice
- (2009) Nathalie Dhomen et al. CANCER CELL
- Defining the Human Deubiquitinating Enzyme Interaction Landscape
- (2009) Mathew E. Sowa et al. CELL
- Final Version of 2009 AJCC Melanoma Staging and Classification
- (2009) Charles M. Balch et al. JOURNAL OF CLINICAL ONCOLOGY
- A comprehensive catalogue of somatic mutations from a human cancer genome
- (2009) Erin D. Pleasance et al. NATURE
- The DNA-damage response in human biology and disease
- (2009) Stephen P. Jackson et al. NATURE
- F-box protein FBXO31 mediates cyclin D1 degradation to induce G1 arrest after DNA damage
- (2009) Manas K. Santra et al. NATURE
- Targeting the ubiquitin system in cancer therapy
- (2009) Daniela Hoeller et al. NATURE
- Genome-wide association study identifies three loci associated with melanoma risk
- (2009) D Timothy Bishop et al. NATURE GENETICS
- Family history of melanoma and Parkinson disease risk
- (2009) X. Gao et al. NEUROLOGY
- Inhibition of Siah2 ubiquitin ligase by vitamin K3 (menadione) attenuates hypoxia and MAPK signaling and blocks melanoma tumorigenesis
- (2009) Meera Shah et al. Pigment Cell & Melanoma Research
- Mechanisms of NKT cell anergy induction involve Cbl-b-promoted monoubiquitination of CARMA1
- (2009) S. Kojo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeting Proteins for Destruction by the Ubiquitin System: Implications for Human Pathobiology
- (2008) Alan L. Schwartz et al. Annual Review of Pharmacology and Toxicology
- Ubiquitin Chain Editing Revealed by Polyubiquitin Linkage-Specific Antibodies
- (2008) Kim Newton et al. CELL
- Shared Principles in NF-κB Signaling
- (2008) Matthew S. Hayden et al. CELL
- Meta-Analysis of Phase II Cooperative Group Trials in Metastatic Stage IV Melanoma to Determine Progression-Free and Overall Survival Benchmarks for Future Phase II Trials
- (2008) Edward L. Korn et al. JOURNAL OF CLINICAL ONCOLOGY
- Pigmentation genes link Parkinson’s disease to melanoma, opening a window on both etiologies
- (2008) Elena Herrero Hernández MEDICAL HYPOTHESES
- cIAP1 and cIAP2 Facilitate Cancer Cell Survival by Functioning as E3 Ligases that Promote RIP1 Ubiquitination
- (2008) Mathieu J.M. Bertrand et al. MOLECULAR CELL
- Diversity of degradation signals in the ubiquitin–proteasome system
- (2008) Tommer Ravid et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Proteomic analysis of ubiquitinated proteins in normal hepatocyte cell line Chang liver cells
- (2008) Fengwei Tan et al. PROTEOMICS
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