MyD88-dependent inflammasome activation and autophagy inhibition contributes to Ehrlichia-induced liver injury and toxic shock

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(2017) Si Ming Man et al.   IMMUNOLOGICAL REVIEWS

Differential roles of caspase-1 and caspase-11 in infection and inflammation

(2017) Si Ming Man et al.   Scientific Reports

Ehrlichia secretes Etf-1 to induce autophagy and capture nutrients for its growth through RAB5 and class III phosphatidylinositol 3-kinase

(2016) Mingqun Lin et al.   Autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

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Hepatocyte mitochondrial DNA drives nonalcoholic steatohepatitis by activation of TLR9

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Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

(2016) Xing Liu et al.   NATURE

Molecular Pathogenesis ofEhrlichia chaffeensisInfection

(2015) Yasuko Rikihisa   Annual Review of Microbiology

The cooperation between the autophagy machinery and the inflammasome to implement an appropriate innate immune response: do they regulate each other?

(2015) Dalia H. A. Abdelaziz et al.   IMMUNOLOGICAL REVIEWS

The inflammasome: firing up innate immunity

(2015) Thirumala-Devi Kanneganti   IMMUNOLOGICAL REVIEWS

Flagellin-induced NLRC4 phosphorylation primes the inflammasome for activation by NAIP5

(2015) Magdalena Matusiak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Natural Killer Cell Sensing of Infected Cells Compensates for MyD88 Deficiency but Not IFN-I Activity in Resistance to Mouse Cytomegalovirus

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Type I Interferons Promote Severe Disease in a Mouse Model of Lethal Ehrlichiosis

(2014) Yubin Zhang et al.   INFECTION AND IMMUNITY

Type I Interferon Signaling Regulates Activation of the Absent in Melanoma 2 Inflammasome during Streptococcus pneumoniae Infection

(2014) R. Fang et al.   INFECTION AND IMMUNITY

Ehrlichia chaffeensis Exploits Host SUMOylation Pathways To Mediate Effector-Host Interactions and Promote Intracellular Survival

(2014) Paige Selvy Dunphy et al.   INFECTION AND IMMUNITY

Guanylate binding proteins promote caspase-11-dependent pyroptosis in response to cytoplasmic LPS

(2014) D. M. Pilla et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Caspase-1-Dependent and -Independent Cell Death Pathways in Burkholderia pseudomallei Infection of Macrophages

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The many uses of autophagosomes

(2013) Amal O. Amer   Autophagy

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Detection of cytosolic bacteria by inflammatory caspases

(2013) Jon A Hagar et al.   CURRENT OPINION IN MICROBIOLOGY

Neutrophils Mediate Immunopathology and Negatively Regulate Protective Immune Responses during Fatal Bacterial Infection-Induced Toxic Shock

(2013) Qin Yang et al.   INFECTION AND IMMUNITY

Ehrlichia moonlighting effectors and interkingdom interactions with the mononuclear phagocyte

(2013) Paige Selvy Dunphy et al.   MICROBES AND INFECTION

TLR2 and Nod2 Mediate Resistance or Susceptibility to Fatal Intracellular Ehrlichia Infection in Murine Models of Ehrlichiosis

(2013) Partho Chattoraj et al.   PLoS One

Caspase-11 Protects Against Bacteria That Escape the Vacuole

(2013) Y. Aachoui et al.   SCIENCE

Noncanonical Inflammasome Activation by Intracellular LPS Independent of TLR4

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Caspase-11 Activation in Response to Bacterial Secretion Systems that Access the Host Cytosol

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Noncanonical Inflammasomes: Caspase-11 Activation and Effector Mechanisms

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Role of type I interferons in inflammasome activation, cell death, and disease during microbial infection

(2013) R. K. Subbarao Malireddi et al.   Frontiers in Cellular and Infection Microbiology

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

Ehrlichia type IV secretion effector ECH0825 is translocated to mitochondria and curbs ROS and apoptosis by upregulating host MnSOD

(2012) Hongyan Liu et al.   CELLULAR MICROBIOLOGY

Identification of Critical Host Mitochondrion-Associated Genes during Ehrlichia chaffeensis Infections

(2012) Tonia Von Ohlen et al.   INFECTION AND IMMUNITY

Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1

(2012) Petr Broz et al.   NATURE

NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens

(2012) Paras K. Anand et al.   NATURE

Salmonella triumphs over autophagy

(2012) Christina Tobin Kåhrström   NATURE REVIEWS MICROBIOLOGY

Transmission Electron Microscopy Reveals Distinct Macrophage- and Tick Cell-Specific Morphological Stages of Ehrlichia chaffeensis

(2012) Sarah E. Dedonder et al.   PLoS One

Autophagosomes induced by a bacterial Beclin 1 binding protein facilitate obligatory intracellular infection

(2012) H. Niu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation

(2011) Greta Guarda et al.   IMMUNITY

The Interaction between IL-18 and IL-18 Receptor Limits the Magnitude of Protective Immunity and Enhances Pathogenic Responses following Infection with Intracellular Bacteria

(2011) P. Ghose et al.   JOURNAL OF IMMUNOLOGY

Streptococcus pneumoniae Stimulates a STING- and IFN Regulatory Factor 3-Dependent Type I IFN Production in Macrophages, which Regulates RANTES Production in Macrophages, Cocultured Alveolar Epithelial Cells, and Mouse Lungs

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Role of the Nlrp3 Inflammasome in Microbial Infection

(2011) Paras K. Anand et al.   Frontiers in Microbiology

Natural Killer Cells Promote Tissue Injury and Systemic Inflammatory Responses During Fatal Ehrlichia-Induced Toxic Shock-Like Syndrome

(2010) Heather L. Stevenson et al.   AMERICAN JOURNAL OF PATHOLOGY

NDP52, a novel autophagy receptor for ubiquitin-decorated cytosolic bacteria

(2010) Natalia von Muhlinen et al.   Autophagy

Human Ehrlichiosis and Anaplasmosis

(2010) Nahed Ismail et al.   CLINICS IN LABORATORY MEDICINE

Obligate intracellular bacterium Ehrlichia inhibiting mitochondrial activity

(2010) Yan Liu et al.   MICROBES AND INFECTION

Anaplasma phagocytophilum and Ehrlichia chaffeensis: subversive manipulators of host cells

(2010) Yasuko Rikihisa   NATURE REVIEWS MICROBIOLOGY

Type I interferons: crucial participants in disease amplification in autoimmunity

(2010) John C. Hall et al.   Nature Reviews Rheumatology

Bifurcation of Toll-Like Receptor 9 Signaling by Adaptor Protein 3

(2010) M. Sasai et al.   SCIENCE

Autophagy within the antigen donor cell facilitates efficient antigen cross-priming of virus-specific CD8+ T cells

(2009) M Uhl et al.   CELL DEATH AND DIFFERENTIATION

Antigen Display, T-Cell Activation, and Immune Evasion during Acute and Chronic Ehrlichiosis

(2009) B. Nandi et al.   INFECTION AND IMMUNITY

Preconditioning with high mobility group box 1 (HMGB1) induces lipopolysaccharide (LPS) tolerance

(2008) Rajesh K. Aneja et al.   JOURNAL OF LEUKOCYTE BIOLOGY