Type I Interferons Promote Severe Disease in a Mouse Model of Lethal Ehrlichiosis

CD11c Expression Identifies a Population of Extrafollicular Antigen-Specific Splenic Plasmablasts Responsible for CD4 T-Independent Antibody Responses during Intracellular Bacterial Infection

(2014) R. Racine et al.   JOURNAL OF IMMUNOLOGY

Endothelial TNF Receptor 2 Induces IRF1 Transcription Factor-Dependent Interferon-β Autocrine Signaling to Promote Monocyte Recruitment

(2013) Deepak Venkatesh et al.   IMMUNITY

Interferon-β Production via Dectin-1-Syk-IRF5 Signaling in Dendritic Cells Is Crucial for Immunity to C. albicans

(2013) Carlos del Fresno et al.   IMMUNITY

Neutrophils Mediate Immunopathology and Negatively Regulate Protective Immune Responses during Fatal Bacterial Infection-Induced Toxic Shock

(2013) Qin Yang et al.   INFECTION AND IMMUNITY

Confounding roles for type I interferons during bacterial and viral pathogenesis

(2013) J. A. Carrero   INTERNATIONAL IMMUNOLOGY

MyD88 Signaling in CD4 T Cells Promotes IFN-  Production and Hematopoietic Progenitor Cell Expansion in Response to Intracellular Bacterial Infection

(2013) Y. Zhang et al.   JOURNAL OF IMMUNOLOGY

TLR2 and Nod2 Mediate Resistance or Susceptibility to Fatal Intracellular Ehrlichia Infection in Murine Models of Ehrlichiosis

(2013) Partho Chattoraj et al.   PLoS One

Type I Interferon Suppresses Type II Interferon-Triggered Human Anti-Mycobacterial Responses

(2013) R. M. B. Teles et al.   SCIENCE

The Regulation of Immune Responses by DC Derived Type I IFN

(2013) Dennis Ng et al.   Frontiers in Immunology

Imbalance of Angiopoietin-1 and Angiopoetin-2 in Severe Dengue and Relationship with Thrombocytopenia, Endothelial Activation, and Vascular Stability

(2012) Meta Michels et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Type I interferon induces CX3CL1 (fractalkine) and CCL5 (RANTES) production in human pulmonary vascular endothelial cells

(2012) M. Nakano et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Constitutive Type I Interferon Modulates Homeostatic Balance through Tonic Signaling

(2012) Daniel J. Gough et al.   IMMUNITY

Structural and dynamic determinants of type I interferon receptor assembly and their functional interpretation

(2012) Jacob Piehler et al.   IMMUNOLOGICAL REVIEWS

IFN-  in the Treatment of Melanoma

(2012) A. A. Tarhini et al.   JOURNAL OF IMMUNOLOGY

Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium

(2012) Nirmal Robinson et al.   NATURE IMMUNOLOGY

Impaired function of the Tie-2 receptor contributes to vascular leakage and lethality in anthrax

(2012) C. C. Ghosh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rickettsiae Induce Microvascular Hyperpermeability via Phosphorylation of VE-Cadherins: Evidence from Atomic Force Microscopy and Biochemical Studies

(2012) Bin Gong et al.   PLoS Neglected Tropical Diseases

Type I interferon signaling regulates the composition of inflammatory infiltrates upon infection with Listeria monocytogenes

(2011) Kristina L. Brzoza-Lewis et al.   CELLULAR IMMUNOLOGY

Innate immune DNA sensing pathways: STING, AIMII and the regulation of interferon production and inflammatory responses

(2011) Glen N Barber   CURRENT OPINION IN IMMUNOLOGY

Expression of type I interferon by splenic macrophages suppresses adaptive immunity during sepsis

(2011) Timo Schwandt et al.   EMBO JOURNAL

RIP Kinase-Dependent Necrosis Drives Lethal Systemic Inflammatory Response Syndrome

(2011) Linde Duprez et al.   IMMUNITY

Emergence of a New Pathogenic Ehrlichia Species, Wisconsin and Minnesota, 2009

(2011) Bobbi S. Pritt et al.   NEW ENGLAND JOURNAL OF MEDICINE

MyD88 and STING Signaling Pathways Are Required for IRF3-Mediated IFN-β Induction in Response to Brucella abortus Infection

(2011) Leonardo A. de Almeida et al.   PLoS One

Induction of IFN-αβ enablesListeria monocytogenesto suppress macrophage activation by IFN-γ

(2010) Manira Rayamajhi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Type I interferon: friend or foe?

(2010) Giorgio Trinchieri   JOURNAL OF EXPERIMENTAL MEDICINE

Infection-Induced Myelopoiesis during Intracellular Bacterial Infection Is Critically Dependent upon IFN-  Signaling

(2010) K. C. MacNamara et al.   JOURNAL OF IMMUNOLOGY

IgM Production by Bone Marrow Plasmablasts Contributes to Long-Term Protection against Intracellular Bacterial Infection

(2010) R. Racine et al.   JOURNAL OF IMMUNOLOGY

An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis

(2010) Matthew P. R. Berry et al.   NATURE

Diminished Hematopoietic Activity Associated with Alterations in Innate and Adaptive Immunity in a Mouse Model of Human Monocytic Ehrlichiosis

(2009) K. C. MacNamara et al.   INFECTION AND IMMUNITY

Type I interferon drives tumor necrosis factor–induced lethal shock

(2009) Liesbeth Huys et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IFNα activates dormant haematopoietic stem cells in vivo

(2009) Marieke A. G. Essers et al.   NATURE

Characterization of the Interferon-Producing Cell in Mice Infected with Listeria monocytogenes

(2009) Silvia Stockinger et al.   PLoS Pathogens

Regulatory Roles of CD1d-Restricted NKT Cells in the Induction of Toxic Shock-Like Syndrome in an Animal Model of Fatal Ehrlichiosis

(2008) H. L. Stevenson et al.   INFECTION AND IMMUNITY

Protective Heterologous Immunity against Fatal Ehrlichiosis and Lack of Protection following Homologous Challenge

(2008) N. R. Thirumalapura et al.   INFECTION AND IMMUNITY

The Importance of Early Treatment With Doxycycline in Human Ehrlichiosis

(2008) Brian J. Hamburg et al.   MEDICINE

Visualization of IFN  production by plasmacytoid versus conventional dendritic cells under specific stimulation conditions in vivo

(2008) S. Scheu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA