Health Benefits of Exercise

Left ventricle transcriptomic analysis reveals connective tissue accumulation associates with initial age-dependent decline in V̇o2peak from its lifetime apex

(2017) Gregory N. Ruegsegger et al.   PHYSIOLOGICAL GENOMICS

Diagnosed and Undiagnosed Diabetes Prevalence by County in the U.S., 1999–2012

(2016) Laura Dwyer-Lindgren et al.   DIABETES CARE

Exercise Inducible Lactate Dehydrogenase B Regulates Mitochondrial Function in Skeletal Muscle

(2016) Xijun Liang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genomic and transcriptomic predictors of response levels to endurance exercise training

(2016) Mark A. Sarzynski et al.   JOURNAL OF PHYSIOLOGY-LONDON

AMPK agonist AICAR delays the initial decline in lifetime-apex V̇o2 peak, while voluntary wheel running fails to delay its initial decline in female rats

(2016) Ryan G. Toedebusch et al.   PHYSIOLOGICAL GENOMICS

Are lower levels of cardiorespiratory fitness associated with incident depression? A systematic review of prospective cohort studies

(2016) Felipe B. Schuch et al.   PREVENTIVE MEDICINE

The genetic regulatory signature of type 2 diabetes in human skeletal muscle

(2016) Laura J. Scott et al.   Nature Communications

Interventions for Human Frailty: Physical Activity as a Model

(2016) Linda P. Fried   Cold Spring Harbor Perspectives in Medicine

The Impact of Endurance Training on Human Skeletal Muscle Memory, Global Isoform Expression and Novel Transcripts

(2016) Maléne E Lindholm et al.   PLoS Genetics

Skeletal muscle as an endocrine organ: PGC-1α, myokines and exercise

(2015) Svenia Schnyder et al.   BONE

Changes in Gene Expression in Responders and Nonresponders to a Low-Intensity Walking Intervention

(2015) Megan E. Osler et al.   DIABETES CARE

Rapidly elevated levels of PGC-1α-b protein in human skeletal muscle after exercise: exploring regulatory factors in a randomized controlled trial

(2015) Eva-karin Gidlund et al.   JOURNAL OF APPLIED PHYSIOLOGY

Separate Effects of Intensity and Amount of Exercise on Interindividual Cardiorespiratory Fitness Response

(2015) Robert Ross et al.   MAYO CLINIC PROCEEDINGS

Musclin is an activity-stimulated myokine that enhances physical endurance

(2015) Ekaterina Subbotina et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exercise-mimetic AICAR transiently benefits brain function

(2015) Davide Guerrieri et al.   Oncotarget

CETP Expression Protects Female Mice from Obesity-Induced Decline in Exercise Capacity

(2015) David A. Cappel et al.   PLoS One

Deletion of Kinin B2 Receptor Alters Muscle Metabolism and Exercise Performance

(2015) Felipe C. G. Reis et al.   PLoS One

Exercise and type 2 diabetes: molecular mechanisms regulating glucose uptake in skeletal muscle

(2014) Kristin I. Stanford et al.   ADVANCES IN PHYSIOLOGY EDUCATION

Improved Physical Fitness Correlates With Improved Cognition in Multiple Sclerosis

(2014) Meghan Beier et al.   ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION

Skeletal Muscle PGC-1α1 Modulates Kynurenine Metabolism and Mediates Resilience to Stress-Induced Depression

(2014) Leandro Z. Agudelo et al.   CELL

Exercise as an add-on strategy for the treatment of major depressive disorder: a systematic review

(2014) Gioia Mura et al.   CNS SPECTRUMS

Muscle-Specific Overexpression of PGC-1α Does Not Augment Metabolic Improvements in Response to Exercise and Caloric Restriction

(2014) Kari E. Wong et al.   DIABETES

Characterization of the metabolic effects of irisin on skeletal musclein vitro

(2014) R. A. Vaughan et al.   DIABETES OBESITY & METABOLISM

Physical Activity Predicts Microstructural Integrity in Memory-Related Networks in Very Old Adults

(2014) Q. Tian et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Preserved Differentiation Between Physical Activity and Cognitive Performance Across Young, Middle, and Older Adulthood Over 8 Years

(2014) A. A. M. Bielak et al.   JOURNALS OF GERONTOLOGY SERIES B-PSYCHOLOGICAL SCIENCES AND SOCIAL SCIENCES

AMPK agonist AICAR improves cognition and motor coordination in young and aged mice

(2014) T. Kobilo et al.   LEARNING & MEMORY

Dose-dependent effectiveness of wheel running to attenuate cocaine-seeking: impact of sex and estrous cycle in rats

(2014) Alexis B. Peterson et al.   PSYCHOPHARMACOLOGY

Physical activity patterns and risk of depression in young adulthood: a 20-year cohort study since childhood

(2014) Charlotte McKercher et al.   SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY

Cessation of voluntary wheel running increases anxiety-like behavior and impairs adult hippocampal neurogenesis in mice

(2013) Takeshi Nishijima et al.   BEHAVIOURAL BRAIN RESEARCH

Exercise Induces Hippocampal BDNF through a PGC-1α/FNDC5 Pathway

(2013) Christiane D. Wrann et al.   Cell Metabolism

Physical Exercise Prevents Stress-Induced Activation of Granule Neurons and Enhances Local Inhibitory Mechanisms in the Dentate Gyrus

(2013) T. J. Schoenfeld et al.   JOURNAL OF NEUROSCIENCE

Age Dependency of Oxygen Uptake and Related Parameters in Exercise Testing: An Expert Opinion on Reference Values Suitable for Adults

(2013) Joachim Schneider   LUNG

Exercise as a novel treatment for drug addiction: A neurobiological and stage-dependent hypothesis

(2013) Wendy J. Lynch et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

VO2max Trainability and High Intensity Interval Training in Humans: A Meta-Analysis

(2013) Andrew P. Bacon et al.   PLoS One

The protective effects of voluntary exercise against the behavioral consequences of uncontrollable stress persist despite an increase in anxiety following forced cessation of exercise

(2012) Benjamin N. Greenwood et al.   BEHAVIOURAL BRAIN RESEARCH

A PGC-1α Isoform Induced by Resistance Training Regulates Skeletal Muscle Hypertrophy

(2012) Jorge L. Ruas et al.   CELL

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

(2012) Pontus Boström et al.   NATURE

PGC-1α is Dispensable for Exercise-Induced Mitochondrial Biogenesis in Skeletal Muscle

(2012) Glenn C. Rowe et al.   PLoS One

Exercise to reduce the escalation of cocaine self-administration in adolescent and adult rats

(2012) Natalie E. Zlebnik et al.   PSYCHOPHARMACOLOGY

Current understanding of increased insulin sensitivity after exercise - emerging candidates

(2011) S. J. Maarbjerg et al.   Acta Physiologica

Cardiorespiratory Fitness and Classification of Risk of Cardiovascular Disease Mortality

(2011) Sachin Gupta et al.   CIRCULATION

Intrinsic Aerobic Capacity Sets a Divide for Aging and Longevity

(2011) Lauren Gerard Koch et al.   CIRCULATION RESEARCH

Endurance factors improve hippocampal neurogenesis and spatial memory in mice

(2011) T. Kobilo et al.   LEARNING & MEMORY

PGC-1α regulation by exercise training and its influences on muscle function and insulin sensitivity

(2010) Vitor A. Lira et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Exercise Capacity and Mortality in Older Men

(2010) Peter Kokkinos et al.   CIRCULATION

Using molecular classification to predict gains in maximal aerobic capacity following endurance exercise training in humans

(2010) James A. Timmons et al.   JOURNAL OF APPLIED PHYSIOLOGY

A transcriptional map of the impact of endurance exercise training on skeletal muscle phenotype

(2010) Pernille Keller et al.   JOURNAL OF APPLIED PHYSIOLOGY

Running enhances spatial pattern separation in mice

(2010) D. J. Creer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cardiorespiratory Fitness as a Quantitative Predictor of All-Cause Mortality and Cardiovascular Events in Healthy Men and Women

(2009) Satoru Kodama   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Lack of adequate appreciation of physical exercise's complexities can pre-empt appropriate design and interpretation in scientific discovery

(2009) F. W. Booth et al.   JOURNAL OF PHYSIOLOGY-LONDON

Exercise protects the cardiovascular system: effects beyond traditional risk factors

(2009) Michael J. Joyner et al.   JOURNAL OF PHYSIOLOGY-LONDON

Physical Activity in the United States Measured by Accelerometer

(2009) RICHARD P. TROIANO et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Four grams of glucose

(2008) David H. Wasserman   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

AMPK and PPARδ Agonists Are Exercise Mimetics

(2008) Vihang A. Narkar et al.   CELL

Signaling mechanisms in skeletal muscle: Acute responses and chronic adaptations to exercise

(2008) Katja S.C. Röckl et al.   IUBMB LIFE

PGC-1α is not mandatory for exercise- and training-induced adaptive gene responses in mouse skeletal muscle

(2007) Lotte Leick et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Endurance exercise performance: the physiology of champions

(2007) Michael J. Joyner et al.   JOURNAL OF PHYSIOLOGY-LONDON