Immunosuppressive capacity of mesenchymal stem cells correlates with metabolic activity and can be enhanced by valproic acid

Umbilical cord-derived mesenchymal stem cells reversed the suppressive deficiency of T regulatory cells from peripheral blood of patients with multiple sclerosis in a co-culture – a preliminary study

(2016) Hongna Yang et al.   Oncotarget

Stem Cell Therapies in Clinical Trials: Progress and Challenges

(2015) Alan Trounson et al.   Cell Stem Cell

Mesenchymal stromal cells derived from various tissues: Biological, clinical and cryopreservation aspects

(2015) Leah A. Marquez-Curtis et al.   CRYOBIOLOGY

A reproducible immunopotency assay to measure mesenchymal stromal cell–mediated T-cell suppression

(2015) Debra D. Bloom et al.   CYTOTHERAPY

Standardization of Good Manufacturing Practice–compliant production of bone marrow–derived human mesenchymal stromal cells for immunotherapeutic applications

(2015) Patrick Wuchter et al.   CYTOTHERAPY

Immunosuppressive capabilities of mesenchymal stromal cells are maintained under hypoxic growth conditions and after gamma irradiation

(2015) Philipp Nold et al.   CYTOTHERAPY

Mesenchymal stromal cells and rheumatic disorders

(2015) Alan Tyndall   IMMUNOLOGY LETTERS

Mesenchymal Stromal Cell Therapy in Hematology: From Laboratory to Clinic and Back Again

(2015) Ann De Becker et al.   STEM CELLS AND DEVELOPMENT

Changes in autophagy, proteasome activity and metabolism to determine a specific signature for acute and chronic senescent mesenchymal stromal cells

(2015) Stefania Capasso et al.   Oncotarget

A robust potency assay highlights significant donor variation of human mesenchymal stem/progenitor cell immune modulatory capacity and extended radio-resistance

(2015) Nina Ketterl et al.   Stem Cell Research & Therapy

In Vivo Effects of Mesenchymal Stromal Cells in Two Patients With Severe Acute Respiratory Distress Syndrome

(2015) Oscar E. Simonson et al.   Stem Cells Translational Medicine

Metabolic regulation of mesenchymal stem cell in expansion and therapeutic application

(2014) Yijun Liu et al.   BIOTECHNOLOGY PROGRESS

Do Cryopreserved Mesenchymal Stromal Cells Display Impaired Immunomodulatory and Therapeutic Properties?

(2014) Guido Moll et al.   STEM CELLS

Mesenchymal stem cell therapy and acute graft-versus-host disease: a review

(2014) Bruna Amorin et al.   Human Cell

T cells from autoimmune patients display reduced sensitivity to immunoregulation by mesenchymal stem cells: Role of IL-2

(2013) Eyal Ben-Ami et al.   AUTOIMMUNITY REVIEWS

The mesenchymal stromal cells dilemma—does a negative phase III trial of random donor mesenchymal stromal cells in steroid-resistant graft-versus-host disease represent a death knell or a bump in the road?

(2013) Jacques Galipeau   CYTOTHERAPY

Good manufacturing practice-compliant animal-free expansion of human bone marrow derived mesenchymal stroma cells in a closed hollow-fiber-based bioreactor

(2012) Philipp Nold et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

GMP-Compliant Isolation and Expansion of Bone Marrow-Derived MSCs in the Closed, Automated Device Quantum Cell Expansion System

(2012) Markus T. Rojewski et al.   CELL TRANSPLANTATION

In vitro assessment of mesenchymal stem cells immunosuppressive potential in multiple sclerosis patients

(2012) Marina M. Zafranskaya et al.   IMMUNOLOGY LETTERS

The Antiepileptic Drug Valproic Acid Restores T Cell Homeostasis and Ameliorates Pathogenesis of Experimental Autoimmune Encephalomyelitis

(2012) Jie Lv et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of valproic acid on the expression of trophic factors in human bone marrow mesenchymal stromal cells

(2012) Goang-Won Cho et al.   NEUROSCIENCE LETTERS

Cryopreserved mesenchymal stromal cells display impaired immunosuppressive properties as a result of heat-shock response and impaired interferon-γ licensing

(2011) Moïra François et al.   CYTOTHERAPY

Unknown

(2011) Sung Choi et al.   MOLECULAR MEDICINE

Prochymal Improves Response Rates In Patients With Steroid-Refractory Acute Graft Versus Host Disease (SR-GVHD) Involving The Liver And Gut: Results Of A Randomized, Placebo-Controlled, Multicenter Phase III Trial In GVHD

(2010) P.J. Martin et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Adult Human Mesenchymal Stem Cells Added to Corticosteroid Therapy for the Treatment of Acute Graft-versus-Host Disease

(2009) Partow Kebriaei et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Deacetylase inhibition increases regulatory T cell function and decreases incidence and severity of collagen-induced arthritis

(2009) Sandra J. Saouaf et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Treatment of refractory acute GVHD with third-party MSC expanded in platelet lysate-containing medium

(2008) M von Bonin et al.   BONE MARROW TRANSPLANTATION

Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study

(2008) Katarina Le Blanc et al.   LANCET