Regulation of astrocyte activation by glycolipids drives chronic CNS inflammation

IFN-γ-dependent activation of the brain’s choroid plexus for CNS immune surveillance and repair

(2013) Gilad Kunis et al.   BRAIN

 4GalT6 is involved in the synthesis of lactosylceramide with less intensity than  4GalT5

(2013) N. Tokuda et al.   GLYCOBIOLOGY

Lactosylceramide Interacts with and Activates Cytosolic Phospholipase A2α

(2013) Hiroyuki Nakamura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Emerging roles of astrocytes in neural circuit development

(2013) Laura E. Clarke et al.   NATURE REVIEWS NEUROSCIENCE

The innate immune system in demyelinating disease

(2012) Lior Mayo et al.   IMMUNOLOGICAL REVIEWS

Multiple sclerosis

(2012) Alyssa Nylander et al.   JOURNAL OF CLINICAL INVESTIGATION

Lipids and lipid-reactive antibodies as biomarkers for multiple sclerosis

(2012) Francisco J. Quintana et al.   JOURNAL OF NEUROIMMUNOLOGY

Genomic Analysis of Reactive Astrogliosis

(2012) J. L. Zamanian et al.   JOURNAL OF NEUROSCIENCE

CNS-specific Therapy for Ongoing EAE by Silencing IL-17 Pathway in Astrocytes

(2012) Yaping Yan et al.   MOLECULAR THERAPY

Regional Astrocyte Allocation Regulates CNS Synaptogenesis and Repair

(2012) H.-H. Tsai et al.   SCIENCE

Leukemia Inhibitory Factor Inhibits T Helper 17 Cell Differentiation and Confers Treatment Effects of Neural Progenitor Cell Therapy in Autoimmune Disease

(2011) Wei Cao et al.   IMMUNITY

IL-17 Silencing Does Not Protect Nonobese Diabetic Mice from Autoimmune Diabetes

(2011) J. Joseph et al.   JOURNAL OF IMMUNOLOGY

Lactosylceramide Mediates the Expression of Adhesion Molecules in TNF-α and IFNγ-stimulated Primary Cultured Astrocytes

(2011) Jin-Koo Lee et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool

(2011) Bahareh Ajami et al.   NATURE NEUROSCIENCE

Heterogeneity of CNS myeloid cells and their roles in neurodegeneration

(2011) Marco Prinz et al.   NATURE NEUROSCIENCE

Repertoire of microglial and macrophage responses after spinal cord injury

(2011) Samuel David et al.   NATURE REVIEWS NEUROSCIENCE

The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence

(2011) J. I. Alvarez et al.   SCIENCE

Inhibition of reactive astrocytosis in established experimental autoimmune encephalomyelitis favors infiltration by myeloid cells over T cells and enhances severity of disease

(2010) Henrik Toft-Hansen et al.   GLIA

β4-Galactosyltransferase-5 is a lactosylceramide synthase essential for mouse extra-embryonic development

(2010) Toshikazu Nishie et al.   GLYCOBIOLOGY

Expander: from expression microarrays to networks and functions

(2010) Igor Ulitsky et al.   Nature Protocols

The challenge of multiple sclerosis: How do we cure a chronic heterogeneous disease?

(2009) Howard L. Weiner   ANNALS OF NEUROLOGY

CCR2+Ly-6Chi monocytes are crucial for the effector phase of autoimmunity in the central nervous system

(2009) Alexander Mildner et al.   BRAIN

Reactive Astrocytes Form Scar-Like Perivascular Barriers to Leukocytes during Adaptive Immune Inflammation of the CNS

(2009) R. R. Voskuhl et al.   JOURNAL OF NEUROSCIENCE

Toll-like receptor 2 and poly(ADP-ribose) polymerase 1 promote central nervous system neuroinflammation in progressive EAE

(2009) Mauricio F Farez et al.   NATURE IMMUNOLOGY

Reversal of axonal loss and disability in a mouse model of progressive multiple sclerosis

(2008) Alexandre S. Basso et al.   JOURNAL OF CLINICAL INVESTIGATION

A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function

(2008) J. D. Cahoy et al.   JOURNAL OF NEUROSCIENCE

Distinct Stages of Myelination Regulated by γ-Secretase and Astrocytes in a Rapidly Myelinating CNS Coculture System

(2008) Trent A. Watkins et al.   NEURON

Antigen microarrays identify unique serum autoantibody signatures in clinical and pathologic subtypes of multiple sclerosis

(2008) F. J. Quintana et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Astroglial Metabolic Networks Sustain Hippocampal Synaptic Transmission

(2008) N. Rouach et al.   SCIENCE