Searching for convergent pathways in autism spectrum disorders: insights from human brain transcriptome studies
出版年份 2016 全文链接
标题
Searching for convergent pathways in autism spectrum disorders: insights from human brain transcriptome studies
作者
关键词
Autism, Brain, Transcriptome
出版物
CELLULAR AND MOLECULAR LIFE SCIENCES
Volume 73, Issue 23, Pages 4517-4530
出版商
Springer Nature
发表日期
2016-07-13
DOI
10.1007/s00018-016-2304-0
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- The Emerging Picture of Autism Spectrum Disorder: Genetics and Pathology
- (2015) Jason A. Chen et al. Annual Review of Pathology-Mechanisms of Disease
- Specific identification and quantification of circular RNAs from sequencing data
- (2015) Jun Cheng et al. BIOINFORMATICS
- A Genome-wide Association Study of Autism Using the Simons Simplex Collection: Does Reducing Phenotypic Heterogeneity in Autism Increase Genetic Homogeneity?
- (2015) Pauline Chaste et al. BIOLOGICAL PSYCHIATRY
- The RNA Binding Protein Quaking Regulates Formation of circRNAs
- (2015) Simon J. Conn et al. CELL
- Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets
- (2015) Evan Z. Macosko et al. CELL
- Recent Advances in the Genetics of Autism Spectrum Disorder
- (2015) Silvia De Rubeis et al. Current Neurology and Neuroscience Reports
- Specific Regional and Age-Related Small Noncoding RNA Expression Patterns Within Superior Temporal Gyrus of Typical Human Brains Are Less Distinct in Autism Brains
- (2015) Boryana Stamova et al. JOURNAL OF CHILD NEUROLOGY
- Shared Pathways Among Autism Candidate Genes Determined by Co-expression Network Analysis of the Developing Human Brain Transcriptome
- (2015) Ahmed Mahfouz et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed
- (2015) Agnieszka Rybak-Wolf et al. MOLECULAR CELL
- Cell cycle networks link gene expression dysregulation, mutation, and brain maldevelopment in autistic toddlers
- (2015) T. Pramparo et al. Molecular Systems Biology
- Coexpression networks identify brain region–specific enhancer RNAs in the human brain
- (2015) Pu Yao et al. NATURE NEUROSCIENCE
- The PsychENCODE project
- (2015) Schahram Akbarian et al. NATURE NEUROSCIENCE
- Mapping DNA methylation across development, genotype and schizophrenia in the human frontal cortex
- (2015) Andrew E Jaffe et al. NATURE NEUROSCIENCE
- Neural circular RNAs are derived from synaptic genes and regulated by development and plasticity
- (2015) Xintian You et al. NATURE NEUROSCIENCE
- Systems biology and gene networks in neurodevelopmental and neurodegenerative disorders
- (2015) Neelroop N. Parikshak et al. NATURE REVIEWS GENETICS
- Determining the role of microRNAs in psychiatric disorders
- (2015) Orna Issler et al. NATURE REVIEWS NEUROSCIENCE
- From the genetic architecture to synaptic plasticity in autism spectrum disorder
- (2015) Thomas Bourgeron NATURE REVIEWS NEUROSCIENCE
- Exon-intron circular RNAs regulate transcription in the nucleus
- (2015) Zhaoyong Li et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Mechanisms of Long Non-coding RNAs in Mammalian Nervous System Development, Plasticity, Disease, and Evolution
- (2015) James A. Briggs et al. NEURON
- LRP8-Reelin-Regulated Neuronal Enhancer Signature Underlying Learning and Memory Formation
- (2015) Francesca Telese et al. NEURON
- Insights into Autism Spectrum Disorder Genomic Architecture and Biology from 71 Risk Loci
- (2015) Stephan J. Sanders et al. NEURON
- RNA transcribed from a distal enhancer is required for activating the chromatin at the promoter of the gonadotropin α-subunit gene
- (2015) Lilach Pnueli et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A survey of human brain transcriptome diversity at the single cell level
- (2015) Spyros Darmanis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Transcription factor trapping by RNA in gene regulatory elements
- (2015) A. A. Sigova et al. SCIENCE
- Exon-intron circular RNAs regulate transcription in the nucleus
- (2015) Zhaoyong Li et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Analysis of Intron Sequences Reveals Hallmarks of Circular RNA Biogenesis in Animals
- (2015) Andranik Ivanov et al. Cell Reports
- Statistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal development
- (2015) Linda Szabo et al. GENOME BIOLOGY
- A comprehensive meta-analysis of common genetic variants in autism spectrum conditions
- (2015) Varun Warrier et al. Molecular Autism
- Convergence of Genes and Cellular Pathways Dysregulated in Autism Spectrum Disorders
- (2014) Dalila Pinto et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Disruptive CHD8 Mutations Define a Subtype of Autism Early in Development
- (2014) Raphael Bernier et al. CELL
- The discovery of integrated gene networks for autism and related disorders
- (2014) Fereydoun Hormozdiari et al. GENOME RESEARCH
- The Familial Risk of Autism
- (2014) Sven Sandin et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Enhancer RNA Facilitates NELF Release from Immediate Early Genes
- (2014) Katie Schaukowitch et al. MOLECULAR CELL
- circRNA Biogenesis Competes with Pre-mRNA Splicing
- (2014) Reut Ashwal-Fluss et al. MOLECULAR CELL
- Synaptic, transcriptional and chromatin genes disrupted in autism
- (2014) Silvia De Rubeis et al. NATURE
- An atlas of active enhancers across human cell types and tissues
- (2014) Robin Andersson et al. NATURE
- Transcriptional landscape of the prenatal human brain
- (2014) Jeremy A. Miller et al. NATURE
- Detecting and characterizing circular RNAs
- (2014) William R Jeck et al. NATURE BIOTECHNOLOGY
- Whole-genome sequence variation, population structure and demographic history of the Dutch population
- (2014) Laurent C Francioli et al. NATURE GENETICS
- Most genetic risk for autism resides with common variation
- (2014) Trent Gaugler et al. NATURE GENETICS
- The rise of regulatory RNA
- (2014) Kevin V. Morris et al. NATURE REVIEWS GENETICS
- The role of long non-coding RNAs in neurodevelopment, brain function and neurological disease
- (2014) T. C. Roberts et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Enhancer RNAs participate in androgen receptor-driven looping that selectively enhances gene activation
- (2014) C.-L. Hsieh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Enhancer RNAs and regulated transcriptional programs
- (2014) Michael T.Y. Lam et al. TRENDS IN BIOCHEMICAL SCIENCES
- Transcriptome analysis reveals dysregulation of innate immune response genes and neuronal activity-dependent genes in autism
- (2014) Simone Gupta et al. Nature Communications
- Genome-wide Analysis of Drosophila Circular RNAs Reveals Their Structural and Sequence Properties and Age-Dependent Neural Accumulation
- (2014) Jakub O. Westholm et al. Cell Reports
- Tissue-Specific RNA Expression Marks Distant-Acting Developmental Enhancers
- (2014) Han Wu et al. PLoS Genetics
- CellMix: a comprehensive toolbox for gene expression deconvolution
- (2013) R. Gaujoux et al. BIOINFORMATICS
- DeconRNASeq: a statistical framework for deconvolution of heterogeneous tissue samples based on mRNA-Seq data
- (2013) Ting Gong et al. BIOINFORMATICS
- Digital sorting of complex tissues for cell type-specific gene expression profiles
- (2013) Yi Zhong et al. BMC BIOINFORMATICS
- Coexpression Networks Implicate Human Midfetal Deep Cortical Projection Neurons in the Pathogenesis of Autism
- (2013) A. Jeremy Willsey et al. CELL
- Integrative Functional Genomic Analyses Implicate Specific Molecular Pathways and Circuits in Autism
- (2013) Neelroop N. Parikshak et al. CELL
- Enhancer transcripts mark active estrogen receptor binding sites
- (2013) N. Hah et al. GENOME RESEARCH
- In vitro-differentiated neural cell cultures progress towards donor-identical brain tissue
- (2013) Brooke E. Hjelm et al. HUMAN MOLECULAR GENETICS
- eRNAs Promote Transcription by Establishing Chromatin Accessibility at Defined Genomic Loci
- (2013) Kambiz Mousavi et al. MOLECULAR CELL
- Circular Intronic Long Noncoding RNAs
- (2013) Yang Zhang et al. MOLECULAR CELL
- Identification of differentially expressed microRNAs across the developing human brain
- (2013) M N Ziats et al. MOLECULAR PSYCHIATRY
- Functional roles of enhancer RNAs for oestrogen-dependent transcriptional activation
- (2013) Wenbo Li et al. NATURE
- Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription
- (2013) Michael T. Y. Lam et al. NATURE
- Epigenetics and ncRNAs in Brain Function and Disease: Mechanisms and Prospects for Therapy
- (2013) Miguel A. Varela et al. Neurotherapeutics
- When Is Hub Gene Selection Better than Standard Meta-Analysis?
- (2013) Peter Langfelder et al. PLoS One
- The Enhancer Landscape during Early Neocortical Development Reveals Patterns of Dense Regulation and Co-option
- (2013) Aaron M. Wenger et al. PLoS Genetics
- Autism in DSM-5: progress and challenges
- (2013) Fred R Volkmar et al. Molecular Autism
- Characterization of Enhancer Function from Genome-Wide Analyses
- (2012) Glenn A. Maston et al. Annual Review of Genomics and Human Genetics
- The Pathophysiology of Fragile X (and What It Teaches Us about Synapses)
- (2012) Asha L. Bhakar et al. Annual Review of Neuroscience
- Global Prevalence of Autism and Other Pervasive Developmental Disorders
- (2012) Mayada Elsabbagh et al. Autism Research
- Aberrant Expression of Long Noncoding RNAs in Autistic Brain
- (2012) Mark N. Ziats et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- eRNAs Are Required for p53-Dependent Enhancer Activity and Gene Transcription
- (2012) Carlos A. Melo et al. MOLECULAR CELL
- Comparative RNA editing in autistic and neurotypical cerebella
- (2012) A Eran et al. MOLECULAR PSYCHIATRY
- An anatomically comprehensive atlas of the adult human brain transcriptome
- (2012) Michael J. Hawrylycz et al. NATURE
- Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants
- (2012) Wenqing Fu et al. NATURE
- Patterns and rates of exonic de novo mutations in autism spectrum disorders
- (2012) Benjamin M. Neale et al. NATURE
- De novo mutations revealed by whole-exome sequencing are strongly associated with autism
- (2012) Stephan J. Sanders et al. NATURE
- Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations
- (2012) Brian J. O’Roak et al. NATURE
- Promoter-proximal pausing of RNA polymerase II: emerging roles in metazoans
- (2012) Karen Adelman et al. NATURE REVIEWS GENETICS
- De Novo Gene Disruptions in Children on the Autistic Spectrum
- (2012) Ivan Iossifov et al. NEURON
- Circular RNAs are abundant, conserved, and associated with ALU repeats
- (2012) W. R. Jeck et al. RNA
- A Noncoding RNA Antisense to Moesin at 5p14.1 in Autism
- (2012) T. Kerin et al. Science Translational Medicine
- The NIH Roadmap Epigenomics Program data resource
- (2012) Lisa Helbling Chadwick Epigenomics
- Networks of Neuronal Genes Affected by Common and Rare Variants in Autism Spectrum Disorders
- (2012) Eyal Ben-David et al. PLoS Genetics
- Common genetic variants, acting additively, are a major source of risk for autism
- (2012) Lambertus Klei et al. Molecular Autism
- Genetic Heritability and Shared Environmental Factors Among Twin Pairs With Autism
- (2011) Joachim Hallmayer ARCHIVES OF GENERAL PSYCHIATRY
- The Human Brain in a Dish: The Promise of iPSC-Derived Neurons
- (2011) Ricardo Dolmetsch et al. CELL
- Mechanisms of neurocognitive dysfunction and therapeutic considerations in tuberous sclerosis complex
- (2011) Peter Tsai et al. CURRENT OPINION IN NEUROLOGY
- Human long non-coding RNAs promote pluripotency and neuronal differentiation by association with chromatin modifiers and transcription factors
- (2011) Shi-Yan Ng et al. EMBO JOURNAL
- Spatio-temporal transcriptome of the human brain
- (2011) Hyo Jung Kang et al. NATURE
- Temporal dynamics and genetic control of transcription in the human prefrontal cortex
- (2011) Carlo Colantuoni et al. NATURE
- Transcriptomic analysis of autistic brain reveals convergent molecular pathology
- (2011) Irina Voineagu et al. NATURE
- Exome sequencing in sporadic autism spectrum disorders identifies severe de novo mutations
- (2011) Brian J O'Roak et al. NATURE GENETICS
- Population-specific expression analysis (PSEA) reveals molecular changes in diseased brain
- (2011) Alexandre Kuhn et al. NATURE METHODS
- Multiple Recurrent De Novo CNVs, Including Duplications of the 7q11.23 Williams Syndrome Region, Are Strongly Associated with Autism
- (2011) Stephan J. Sanders et al. NEURON
- RNA-Seq of Human Neurons Derived from iPS Cells Reveals Candidate Long Non-Coding RNAs Involved in Neurogenesis and Neuropsychiatric Disorders
- (2011) Mingyan Lin et al. PLoS One
- Prioritizing GWAS Results: A Review of Statistical Methods and Recommendations for Their Application
- (2010) Rita M. Cantor et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Genotator: A disease-agnostic tool for genetic annotation of disease
- (2010) Dennis P Wall et al. BMC Medical Genomics
- A genome-wide scan for common alleles affecting risk for autism
- (2010) R. Anney et al. HUMAN MOLECULAR GENETICS
- Engineered Alterations in RNA Editing Modulate Complex Behavior inDrosophila
- (2010) James E. C. Jepson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Comprehensive analysis of the chromatin landscape in Drosophila melanogaster
- (2010) Peter V. Kharchenko et al. NATURE
- Widespread transcription at neuronal activity-regulated enhancers
- (2010) Tae-Kyung Kim et al. NATURE
- Functional impact of global rare copy number variation in autism spectrum disorders
- (2010) Dalila Pinto et al. NATURE
- A genome-wide linkage and association scan reveals novel loci for autism
- (2009) Lauren A. Weiss et al. NATURE
- Common genetic variants on 5p14.1 associate with autism spectrum disorders
- (2009) Kai Wang et al. NATURE
- Autism genome-wide copy number variation reveals ubiquitin and neuronal genes
- (2009) Joseph T. Glessner et al. NATURE
- Structural Variation of Chromosomes in Autism Spectrum Disorder
- (2008) Christian R. Marshall et al. AMERICAN JOURNAL OF HUMAN GENETICS
- WGCNA: an R package for weighted correlation network analysis
- (2008) Peter Langfelder et al. BMC BIOINFORMATICS
- RNA-Seq: a revolutionary tool for transcriptomics
- (2008) Zhong Wang et al. NATURE REVIEWS GENETICS
- Immune transcriptome alterations in the temporal cortex of subjects with autism
- (2008) Krassimira Garbett et al. NEUROBIOLOGY OF DISEASE
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