Molecular adaptations underlying the beneficial effects of hydroxytyrosol in the pathogenic alterations induced by a high-fat diet in mouse liver: PPAR-α and Nrf2 activation, and NF-κB down-regulation
出版年份 2017 全文链接
标题
Molecular adaptations underlying the beneficial effects of hydroxytyrosol in the pathogenic alterations induced by a high-fat diet in mouse liver: PPAR-α and Nrf2 activation, and NF-κB down-regulation
作者
关键词
-
出版物
Food & Function
Volume 8, Issue 4, Pages 1526-1537
出版商
Royal Society of Chemistry (RSC)
发表日期
2017-03-20
DOI
10.1039/c7fo00090a
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- The LC–MS-based metabolomics of hydroxytyrosol administration in rats reveals amelioration of the metabolic syndrome
- (2017) Nikolaos Lemonakis et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- Hydroxytyrosol prevents reduction in liver activity of Δ-5 and Δ-6 desaturases, oxidative stress, and depletion in long chain polyunsaturated fatty acid content in different tissues of high-fat diet fed mice
- (2017) Rodrigo Valenzuela et al. Lipids in Health and Disease
- Hydroxytyrosol ameliorates metabolic, cardiovascular and liver changes in a rat model of diet-induced metabolic syndrome: Pharmacological and metabolism-based investigation
- (2017) Hemant Poudyal et al. PHARMACOLOGICAL RESEARCH
- Cell type-specific modulation of lipid mediator's formation in murine adipose tissue by omega-3 fatty acids
- (2016) Ondrej Kuda et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Non-alcoholic fatty liver disease in 2016
- (2016) S.A. Townsend et al. BRITISH MEDICAL BULLETIN
- Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes
- (2016) Zobair M. Younossi et al. HEPATOLOGY
- Hydroxytyrosol prevents metabolic impairment reducing hepatic inflammation and restoring duodenal integrity in a rat model of NAFLD
- (2016) Claudio Pirozzi et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Supplementation with antioxidant-rich extra virgin olive oil prevents hepatic oxidative stress and reduction of desaturation capacity in mice fed a high-fat diet: Effects on fatty acid composition in liver and extrahepatic tissues
- (2016) Miguel Angel Rincón-Cervera et al. NUTRITION
- Long-chain polyunsaturated fatty acids regulation of PPARs, signaling: Relationship to tissue development and aging
- (2016) Francisca Echeverría et al. PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS
- Hydroxytyrosol improves mitochondrial function and reduces oxidative stress in the brain of db/db mice: role of AMP-activated protein kinase activation
- (2015) Adi Zheng et al. BRITISH JOURNAL OF NUTRITION
- The role of olive oil in disease prevention: a focus on the recent epidemiological evidence from cohort studies and dietary intervention trials
- (2015) Genevieve Buckland et al. BRITISH JOURNAL OF NUTRITION
- Relevant Aspects of Nutritional and Dietary Interventions in Non-Alcoholic Fatty Liver Disease
- (2015) Maria Hernandez-Rodas et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Modulation of hepatic lipid metabolism by olive oil and its phenols in nonalcoholic fatty liver disease
- (2015) Paola Priore et al. IUBMB LIFE
- Dose effect on the uptake and accumulation of hydroxytyrosol and its metabolites in target tissues in rats
- (2015) Maria-Carmen López de las Hazas et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Protective effect of hydroxytyrosol and its predominant plasmatic human metabolites against endothelial dysfunction in human aortic endothelial cells
- (2015) Úrsula Catalán et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Olive oil and its phenolic compounds (hydroxytyrosol and tyrosol) ameliorated TCDD-induced heptotoxicity in rats via inhibition of oxidative stress and apoptosis
- (2015) Ilavarasi Kalaiselvan et al. PHARMACEUTICAL BIOLOGY
- Reduction in the desaturation capacity of the liver in mice subjected to high fat diet: Relation to LCPUFA depletion in liver and extrahepatic tissues
- (2015) Rodrigo Valenzuela et al. PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS
- Hydroxytyrosol, a natural molecule from olive oil, suppresses the growth of human hepatocellular carcinoma cells via inactivating AKT and nuclear factor-kappa B pathways
- (2014) Baolei Zhao et al. CANCER LETTERS
- High-fat diet triggers Mallory-Denk body formation through misfolding and crosslinking of excess keratin 8
- (2014) Ozlem Kucukoglu et al. HEPATOLOGY
- Beneficial effects of the olive oil phenolic components oleuropein and hydroxytyrosol: focus on protection against cardiovascular and metabolic diseases
- (2014) Stefania Bulotta et al. Journal of Translational Medicine
- N-3long-chain PUFA supplementation prevents high fat diet induced mouse liver steatosis and inflammation in relation to PPAR-α upregulation and NF-κB DNA binding abrogation
- (2014) Gladys Tapia et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Chronic hydroxytyrosol feeding modulates glutathione-mediated oxido-reduction pathways in adipose tissue: A nutrigenomic study
- (2014) E. Giordano et al. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
- Role of endoplasmic reticulum stress in the pathogenesis of nonalcoholic fatty liver disease
- (2014) Xue-Qun Zhang WORLD JOURNAL OF GASTROENTEROLOGY
- High fat diet feeding results in gender specific steatohepatitis and inflammasome activation
- (2014) Michal Ganz WORLD JOURNAL OF GASTROENTEROLOGY
- Enhanced endoplasmic reticulum SERCA activity by overexpression of hepatic stimulator substance gene prevents hepatic cells from ER stress-induced apoptosis
- (2013) Jing Zhang et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Hydroxytyrosol attenuates tunicamycin-induced endoplasmic reticulum stress in human hepatocarcinoma cells
- (2013) Elena Giordano et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Hydroxytyrosol is not genotoxic in vitro
- (2013) David Auñon-Calles et al. PHARMACOLOGICAL RESEARCH
- The innate immune response during liver inflammation and metabolic disease
- (2013) Veerle Bieghs et al. TRENDS IN IMMUNOLOGY
- A Diet Rich in Olive Oil Phenolics Reduces Oxidative Stress in the Heart of SAMP8 Mice by Induction of Nrf2-Dependent Gene Expression
- (2012) Banu Bayram et al. REJUVENATION RESEARCH
- The importance of the long-chain polyunsaturated fatty acid n-6/n-3 ratio in development of non-alcoholic fatty liver associated with obesity
- (2011) Rodrigo Valenzuela et al. Food & Function
- Liver NF-κB and AP-1 activation and PPAR-α expression are negatively correlated in obese patients: Pro-inflammatory implications
- (2010) Luis A. Videla CLINICAL NUTRITION
- Evolution of inflammation in nonalcoholic fatty liver disease: The multiple parallel hits hypothesis
- (2010) Herbert Tilg et al. HEPATOLOGY
- Olive Leaf Extract Attenuates Cardiac, Hepatic, and Metabolic Changes in High Carbohydrate–, High Fat–Fed Rats
- (2010) Hemant Poudyal et al. JOURNAL OF NUTRITION
- Hydroxytyrosol induces antioxidant/detoxificant enzymes and Nrf2 translocation via extracellular regulated kinases and phosphatidylinositol-3-kinase/protein kinase B pathways in HepG2 cells
- (2010) María Angeles Martín et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Enhancement in liver SREBP-1c/PPAR-α ratio and steatosis in obese patients: Correlations with insulin resistance and n-3 long-chain polyunsaturated fatty acid depletion
- (2009) Paulina Pettinelli et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Obesity-induced insulin resistance and hepatic steatosis are alleviated by ω-3 fatty acids: a role for resolvins and protectins
- (2009) Ana González-Périz et al. FASEB JOURNAL
- The Nrf2-Antioxidant Response Element Signaling Pathway and Its Activation by Oxidative Stress
- (2009) Truyen Nguyen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Decreased Liver Fatty Acid Δ-6 and Δ-5 Desaturase Activity in Obese Patients
- (2009) Julia Araya et al. Obesity
- Liver NF-κB and AP-1 DNA Binding in Obese Patients
- (2009) Luis A. Videla et al. Obesity
- Molecular determinants of insulin resistance, cell apoptosis and lipid accumulation in non-alcoholic steatohepatitis
- (2007) S. Piro et al. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now