Hydroxytyrosol improves mitochondrial function and reduces oxidative stress in the brain of db/db mice: role of AMP-activated protein kinase activation

Diabetes, markers of brain pathology and cognitive function

(2013) Chengxuan Qiu et al.   ANNALS OF NEUROLOGY

The Crosstalk Between Nrf2 and AMPK Signal Pathways Is Important for the Anti-Inflammatory Effect of Berberine in LPS-Stimulated Macrophages and Endotoxin-Shocked Mice

(2013) Chunfen Mo et al.   ANTIOXIDANTS & REDOX SIGNALING

Production of Reactive Oxygen Species in the Diabetic Heart

(2013) Yasushi Teshima et al.   CIRCULATION JOURNAL

Brain Atrophy in Type 2 Diabetes: Regional distribution and influence on cognition

(2013) C. Moran et al.   DIABETES CARE

Mediterranean Diet, Cognitive Function, and Dementia

(2013) Ilianna Lourida et al.   EPIDEMIOLOGY

Hydroxytyrosol prevents diet-induced metabolic syndrome and attenuates mitochondrial abnormalities in obese mice

(2013) Ke Cao et al.   FREE RADICAL BIOLOGY AND MEDICINE

Diabetes-induced Central Neuritic Dystrophy and Cognitive Deficits Are Associated with the Formation of Oligomeric Reticulon-3 via Oxidative Stress

(2013) Bei Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hyperglycemia magnifies bupivacaine-induced cell apoptosis triggered by mitochondria dysfunction and endoplasmic reticulum stress

(2013) Le Li et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Berberine, a natural antidiabetes drug, attenuates glucose neurotoxicity and promotes Nrf2-related neurite outgrowth

(2013) Ya-Yun Hsu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Diabetic db/db mice exhibit central nervous system and peripheral molecular alterations as seen in neurological disorders

(2013) A Ernst et al.   Translational Psychiatry

Impaired adenosine monophosphate-activated protein kinase signalling in dorsal root ganglia neurons is linked to mitochondrial dysfunction and peripheral neuropathy in diabetes

(2012) Subir K. Roy Chowdhury et al.   BRAIN

Insulin signaling, glucose metabolism and mitochondria: Major players in Alzheimer's disease and diabetes interrelation

(2012) Sónia C. Correia et al.   BRAIN RESEARCH

Mitochondria, Diabetes, and Alzheimer’s Disease

(2012) Margherita Milone   DIABETES

Protective Role of Morin, a Flavonoid, against High Glucose Induced Oxidative Stress Mediated Apoptosis in Primary Rat Hepatocytes

(2012) Radhika Kapoor et al.   PLoS One

Coenzyme Q10 prevents peripheral neuropathy and attenuates neuron loss in the db-/db- mouse, a type 2 diabetes model

(2012) T.-J. S. Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bioenergy sensing in the brain

(2011) Stephen Amato et al.   CELL CYCLE

Resveratrol Improves Oxidative Stress and Protects Against Diabetic Nephropathy Through Normalization of Mn-SOD Dysfunction in AMPK/SIRT1-Independent Pathway

(2011) M. Kitada et al.   DIABETES

Adhesion Molecules, Altered Vasoreactivity, and Brain Atrophy in Type 2 Diabetes

(2011) V. Novak et al.   DIABETES CARE

IDF Diabetes Atlas: Global estimates of the prevalence of diabetes for 2011 and 2030

(2011) David R. Whiting et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Hydroxytyrosol reduces intracellular reactive oxygen species levels in vascular endothelial cells by upregulating catalase expression through the AMPK–FOXO3a pathway

(2011) Houda Zrelli et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Stimulation of GSH synthesis to prevent oxidative stress-induced apoptosis by hydroxytyrosol in human retinal pigment epithelial cells: activation of Nrf2 and JNK-p62/SQSTM1 pathways

(2011) Xuan Zou et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Effects of hydroxytyrosol-enriched sunflower oil consumption on CVD risk factors

(2010) Miguel Vázquez-Velasco et al.   BRITISH JOURNAL OF NUTRITION

Hydroxytyrosol protects against oxidative damage by simultaneous activation of mitochondrial biogenesis and phase II detoxifying enzyme systems in retinal pigment epithelial cells

(2010) Lu Zhu et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Nitric oxide and AMPK cooperatively regulate PGC-1α in skeletal muscle cells

(2010) Vitor A. Lira et al.   JOURNAL OF PHYSIOLOGY-LONDON

Cerebral cortical thickness in patients with type 2 diabetes

(2010) Manon Brundel et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Fibroblast growth factor 21 regulates energy metabolism by activating the AMPK–SIRT1–PGC-1α pathway

(2010) Mary D. L. Chau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AMPK in the brain: its roles in energy balance and neuroprotection

(2009) Gabriele V. Ronnett et al.   JOURNAL OF NEUROCHEMISTRY

Hydroxytyrosol promotes mitochondrial biogenesis and mitochondrial function in 3T3-L1 adipocytes

(2009) Jiejie Hao et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Immunohistochemical analysis of human brain suggests pathological synergism of Alzheimer's disease and diabetes mellitus

(2009) Tony Valente et al.   NEUROBIOLOGY OF DISEASE

Activity-Regulated Cytoskeleton-Associated Protein in Rodent Brain is Down-Regulated by High Fat Dietin vivoand by 27-Hydroxycholesterolin vitro

(2008) Laura Mateos et al.   BRAIN PATHOLOGY

Measurement of free hydroxytyrosol in microdialysates from blood and brain of anesthetized rats by liquid chromatography with fluorescence detection

(2008) Yu-Tse Wu et al.   JOURNAL OF CHROMATOGRAPHY A