Cellular Senescence in Age-Related Macular Degeneration: Can Autophagy and DNA Damage Response Play a Role?
出版年份 2017 全文链接
标题
Cellular Senescence in Age-Related Macular Degeneration: Can Autophagy and DNA Damage Response Play a Role?
作者
关键词
-
出版物
Oxidative Medicine and Cellular Longevity
Volume 2017, Issue -, Pages 1-15
出版商
Hindawi Limited
发表日期
2017-11-05
DOI
10.1155/2017/5293258
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Autophagy in UV Damage Response
- (2017) Ashley Sample et al. PHOTOCHEMISTRY AND PHOTOBIOLOGY
- Repair, Reuse, Recycle: The Expanding Role of Autophagy in Genome Maintenance
- (2017) Graeme Hewitt et al. TRENDS IN CELL BIOLOGY
- Drusen maculopathy: a risk factor for visual deterioration
- (2016) Peep V. Algvere et al. ACTA OPHTHALMOLOGICA
- Geo-Epidemiology of Age-Related Macular Degeneration: New Clues Into the Pathogenesis
- (2016) Michele Reibaldi et al. AMERICAN JOURNAL OF OPHTHALMOLOGY
- How autophagy both activates and inhibits cellular senescence
- (2016) Chanhee Kang et al. Autophagy
- Autophagy regulates death of retinal pigment epithelium cells in age-related macular degeneration
- (2016) Kai Kaarniranta et al. CELL BIOLOGY AND TOXICOLOGY
- Inflammation and its role in age-related macular degeneration
- (2016) Anu Kauppinen et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Morphological and Functional Characteristic of Senescent Cancer Cells
- (2016) Ewa Sikora et al. CURRENT DRUG TARGETS
- Mitochondria are required for pro‐ageing features of the senescent phenotype
- (2016) Clara Correia‐Melo et al. EMBO JOURNAL
- Inhibition of DNA methyltransferase or histone deacetylase protects retinal pigment epithelial cells from DNA damage induced by oxidative stress by the stimulation of antioxidant enzymes
- (2016) Paulina Tokarz et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Increased retinal mtDNA damage in the CFH variant associated with age-related macular degeneration
- (2016) Deborah A. Ferrington et al. EXPERIMENTAL EYE RESEARCH
- Oxidative stress and hypoxia in normal and leukemic stem cells
- (2016) Ugo Testa et al. EXPERIMENTAL HEMATOLOGY
- Mitochondrial DNA damage induced autophagy cell death and disease
- (2016) Bennett Van Houten Frontiers in Bioscience-Landmark
- Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
- (2016) Darren J. Baker et al. NATURE
- NOX4 downregulation leads to senescence of human vascular smooth muscle cells
- (2016) Dorota Przybylska et al. Oncotarget
- Is senescence-associated β-galactosidase a marker of neuronal senescence?
- (2016) Malgorzata Piechota et al. Oncotarget
- Oxidative stress-induced premature senescence dysregulates VEGF and CFH expression in retinal pigment epithelial cells: Implications for Age-related Macular Degeneration
- (2016) Mariela C. Marazita et al. Redox Biology
- DNA Damage: From Chronic Inflammation to Age-Related Deterioration
- (2016) Anna Ioannidou et al. Frontiers in Genetics
- DNA Damage Response and Autophagy: A Meaningful Partnership
- (2016) Aristides G. Eliopoulos et al. Frontiers in Genetics
- Advances in Autophagy Regulatory Mechanisms
- (2016) Laura Gallagher et al. Cells
- IL1- and TGFβ-Nox4 signaling, oxidative stress and DNA damage response are shared features of replicative, oncogene-induced, and drug-induced paracrine ‘Bystander senescence’
- (2016) Sona Hubackova et al. Aging-US
- Exogenous NAD+ decreases oxidative stress and protects H2O2-treated RPE cells against necrotic death through the up-regulation of autophagy
- (2016) Ying Zhu et al. Scientific Reports
- The marine n-3 PUFA DHA evokes cytoprotection against oxidative stress and protein misfolding by inducing autophagy and NFE2L2 in human retinal pigment epithelial cells
- (2015) Ida Johansson et al. Autophagy
- Mitochondria: Are they causal players in cellular senescence?
- (2015) Clara Correia-Melo et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype
- (2015) Nicolás Herranz et al. NATURE CELL BIOLOGY
- MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation
- (2015) Remi-Martin Laberge et al. NATURE CELL BIOLOGY
- Cellular senescence in aging and age-related disease: from mechanisms to therapy
- (2015) Bennett G Childs et al. NATURE MEDICINE
- Idebenone Prevents Oxidative Stress, Cell Death and Senescence of Retinal Pigment Epithelium Cells by Stabilizing BAX/Bcl-2 Ratio
- (2015) Nicole Arend et al. OPHTHALMOLOGICA
- αvβ5 Integrin/FAK/PGC-1α Pathway Confers Protective Effects on Retinal Pigment Epithelium
- (2015) Murilo F. Roggia et al. PLoS One
- The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4
- (2015) C. Kang et al. SCIENCE
- Methylglyoxal, a reactive glucose metabolite, enhances autophagy flux and suppresses proliferation of human retinal pigment epithelial ARPE-19 cells
- (2015) Yo-Chen Chang et al. TOXICOLOGY IN VITRO
- Gastric tumor-initiating CD44+ cells and epithelial-mesenchymal transition are inhibited by γ-secretase inhibitor DAPT
- (2015) LU-CHUN LI et al. Oncology Letters
- Controlled induction of DNA double-strand breaks in the mouse liver induces features of tissue ageing
- (2015) Ryan R. White et al. Nature Communications
- Polyploidy Formation in Doxorubicin-Treated Cancer Cells Can Favor Escape from Senescence
- (2015) Grazyna Mosieniak et al. NEOPLASIA
- Determinants and Functions of Mitochondrial Behavior
- (2014) Katherine Labbé et al. Annual Review of Cell and Developmental Biology
- Dysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD
- (2014) Sayak K Mitter et al. Autophagy
- p62 provides dual cytoprotection against oxidative stress in the retinal pigment epithelium
- (2014) Lei Wang et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Senescent cells: SASPected drivers of age-related pathologies
- (2014) Yossi Ovadya et al. BIOGERONTOLOGY
- Oxidative stress and autophagy: the clash between damage and metabolic needs
- (2014) G Filomeni et al. CELL DEATH AND DIFFERENTIATION
- Cellular senescence and the senescent secretory phenotype in age-related chronic diseases
- (2014) Yi Zhu et al. CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
- Redox regulation of antioxidants, autophagy, and the response to stress: Implications for electrophile therapeutics
- (2014) Anna-Liisa Levonen et al. FREE RADICAL BIOLOGY AND MEDICINE
- Subcellular Distribution and Activity of Mechanistic Target of Rapamycin in Aged Retinal Pigment Epithelium
- (2014) B. Yu et al. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
- Chronic Inflammation (Inflammaging) and Its Potential Contribution to Age-Associated Diseases
- (2014) C. Franceschi et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- The role of senescent cells in ageing
- (2014) Jan M. van Deursen NATURE
- The Role of Nibrin in Doxorubicin-Induced Apoptosis and Cell Senescence in Nijmegen Breakage Syndrome Patients Lymphocytes
- (2014) Olga Alster et al. PLoS One
- Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis
- (2014) Wan Ling Wong et al. Lancet Global Health
- Global prevalence of age-related macular degeneration
- (2014) Jost B Jonas Lancet Global Health
- Balance between autophagic pathways preserves retinal homeostasis
- (2013) Natalia Rodríguez-Muela et al. AGING CELL
- Autophagy and senescence
- (2013) David A. Gewirtz Autophagy
- Autophagy and heterophagy dysregulation leads to retinal pigment epithelium dysfunction and development of age-related macular degeneration
- (2013) Kai Kaarniranta et al. Autophagy
- A comparison of replicative senescence and doxorubicin-induced premature senescence of vascular smooth muscle cells isolated from human aorta
- (2013) Anna Bielak-Zmijewska et al. BIOGERONTOLOGY
- Immunosurveillance of senescent cells: the bright side of the senescence program
- (2013) Adi Sagiv et al. BIOGERONTOLOGY
- Calyxin Y induces hydrogen peroxide-dependent autophagy and apoptosis via JNK activation in human non-small cell lung cancer NCI-H460 cells
- (2013) Chao Zhang et al. CANCER LETTERS
- The Hallmarks of Aging
- (2013) Carlos López-Otín et al. CELL
- HtrA1 is induced by oxidative stress and enhances cell senescence through p38 MAPK pathway
- (2013) Supanji et al. EXPERIMENTAL EYE RESEARCH
- Global genomic profiling reveals an extensive p53-regulated autophagy program contributing to key p53 responses
- (2013) D. Kenzelmann Broz et al. GENES & DEVELOPMENT
- Cellular and molecular mechanisms of age-related macular degeneration: From impaired autophagy to neovascularization
- (2013) Alexa Klettner et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Mitochondrial and Nuclear DNA Damage and Repair in Age-Related Macular Degeneration
- (2013) Janusz Blasiak et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Transmitting senescence to the cell neighbourhood
- (2013) Matthew Hoare et al. NATURE CELL BIOLOGY
- Postmitotic neurons develop a p21-dependent senescence-like phenotype driven by a DNA damage response
- (2012) Diana Jurk et al. AGING CELL
- Senescent Cells: A Novel Therapeutic Target for Aging and Age-Related Diseases
- (2012) R M Naylor et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Association between polymorphisms of the DNA base excision repair genes MUTYH and hOGG1 and age-related macular degeneration
- (2012) Ewelina Synowiec et al. EXPERIMENTAL EYE RESEARCH
- Rejuvenation of senescent cells—The road to postponing human aging and age-related disease?
- (2012) Ewa Sikora EXPERIMENTAL GERONTOLOGY
- RPE cell senescence: A key contributor to age-related macular degeneration
- (2012) Michael R. Kozlowski MEDICAL HYPOTHESES
- Consequences of oxidative stress in age-related macular degeneration
- (2012) Stuart G. Jarrett et al. MOLECULAR ASPECTS OF MEDICINE
- The roles of DNA polymerase ζ and the Y family DNA polymerases in promoting or preventing genome instability
- (2012) Shilpy Sharma et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- The Transcription Factor TFEB Links mTORC1 Signaling to Transcriptional Control of Lysosome Homeostasis
- (2012) A. Roczniak-Ferguson et al. Science Signaling
- PGC-1 Rescues Huntington's Disease Proteotoxicity by Preventing Oxidative Stress and Promoting TFEB Function
- (2012) T. Tsunemi et al. Science Translational Medicine
- Selective autophagy mediated by autophagic adapter proteins
- (2011) Terje Johansen et al. Autophagy
- Autophagy: Renovation of Cells and Tissues
- (2011) Noboru Mizushima et al. CELL
- Autophagy and Aging
- (2011) David C. Rubinsztein et al. CELL
- Pseudo-DNA damage response in senescent cells
- (2011) Tatyana V. Pospelova et al. CELL CYCLE
- Emerging role of NF-κB signaling in the induction of senescence-associated secretory phenotype (SASP)
- (2011) Antero Salminen et al. CELLULAR SIGNALLING
- p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype
- (2011) Adam Freund et al. EMBO JOURNAL
- Enhanced retinal pigment epithelium regeneration after injury in MRL/MpJ mice
- (2011) Huiming Xia et al. EXPERIMENTAL EYE RESEARCH
- Mitophagy Plays an Essential Role in Reducing Mitochondrial Production of Reactive Oxygen Species and Mutation of Mitochondrial DNA by Maintaining Mitochondrial Quantity and Quality in Yeast
- (2011) Yusuke Kurihara et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
- (2011) Darren J. Baker et al. NATURE
- Multiple Pathways to the Same End: Mechanisms of Myonuclear Apoptosis in Sarcopenia of Aging
- (2011) Emanuele Marzetti et al. TheScientificWorldJOURNAL
- Impact of cellular senescence signature on ageing research
- (2010) Ewa Sikora et al. AGEING RESEARCH REVIEWS
- Age-associated increase in heterochromatic marks in murine and primate tissues
- (2010) Jill A. Kreiling et al. AGING CELL
- The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression
- (2010) Jean-Philippe Coppé et al. Annual Review of Pathology-Mechanisms of Disease
- Under the ROS: Thiol network is the principal suspect for autophagy commitment
- (2010) Giuseppe Filomeni et al. Autophagy
- Autophagy regulation by p53
- (2010) Maria Chiara Maiuri et al. CURRENT OPINION IN CELL BIOLOGY
- Can autophagy promote longevity?
- (2010) Frank Madeo et al. NATURE CELL BIOLOGY
- The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1
- (2010) Masaaki Komatsu et al. NATURE CELL BIOLOGY
- Progeria syndromes and ageing: what is the connection?
- (2010) Christopher R. Burtner et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS
- (2010) A. Alexander et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inflammatory networks during cellular senescence: causes and consequences
- (2010) Adam Freund et al. TRENDS IN MOLECULAR MEDICINE
- Delayed kinetics of DNA double-strand break processing in normal and pathological aging
- (2009) Olga A. Sedelnikova et al. AGING CELL
- DNA damage response and cellular senescence in tissues of aging mice
- (2009) Chunfang Wang et al. AGING CELL
- PARP-1 is involved in autophagy induced by DNA damage
- (2009) José Antonio Muñoz-Gámez et al. Autophagy
- Autophagy Suppresses Tumorigenesis through Elimination of p62
- (2009) Robin Mathew et al. CELL
- Superoxide is the major reactive oxygen species regulating autophagy
- (2009) Y Chen et al. CELL DEATH AND DIFFERENTIATION
- Autophagy mediates the mitotic senescence transition
- (2009) A. R.J. Young et al. GENES & DEVELOPMENT
- Regulation of Autophagy by Reactive Oxygen Species (ROS): Implications for Cancer Progression and Treatment
- (2008) Meghan B. Azad et al. ANTIOXIDANTS & REDOX SIGNALING
- Oncogene-Induced Senescence Relayed by an Interleukin-Dependent Inflammatory Network
- (2008) Thomas Kuilman et al. CELL
- Prematurely senescent ARPE-19 cells display features of age-related macular degeneration
- (2008) Anne-Lise Glotin et al. FREE RADICAL BIOLOGY AND MEDICINE
- Cellular senescence and organismal aging
- (2008) Jessie C. Jeyapalan et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Mitochondrial DNA damage and its potential role in retinal degeneration
- (2008) S JARRETT et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Both telomeric and non-telomeric DNA damage are determinants of mammalian cellular senescence
- (2008) Asako J Nakamura et al. Epigenetics & Chromatin
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started