Mitochondrial and Nuclear DNA Damage and Repair in Age-Related Macular Degeneration

Mitochondrial (‘mild’) uncoupling and ROS production: physiologically relevant or not?

(2012) Irina G. Shabalina et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Nucleotide Excision DNA Repair Is Associated With Age-Related Vascular Dysfunction

(2012) Matej Durik et al.   CIRCULATION

Association between polymorphisms of the DNA base excision repair genes MUTYH and hOGG1 and age-related macular degeneration

(2012) Ewelina Synowiec et al.   EXPERIMENTAL EYE RESEARCH

Chemical and biological consequences of oxidatively damaged guanine in DNA

(2012) Sarah Delaney et al.   FREE RADICAL RESEARCH

Genetic Variability in DNA Repair Proteins in Age-Related Macular Degeneration

(2012) Janusz Blasiak et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Synaptic Proteome Changes in a DNA Repair Deficient Ercc1 Mouse Model of Accelerated Aging

(2012) Marlene J. Végh et al.   JOURNAL OF PROTEOME RESEARCH

Minimizing the damage: repair pathways keep mitochondrial DNA intact

(2012) Lawrence Kazak et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Single deletions in mitochondrial DNA – Molecular mechanisms and disease phenotypes in clinical practice

(2012) R.D.S. Pitceathly et al.   NEUROMUSCULAR DISORDERS

Mitochondrial quality control: an integrated network of pathways

(2012) Fabian Fischer et al.   TRENDS IN BIOCHEMICAL SCIENCES

A Review: Role of Ultraviolet Radiation in Age-Related Macular Degeneration

(2011) K V Chalam et al.   Eye & Contact Lens-Science and Clinical Practice

Oxidative stress: The achilles' heel of neurodegenerative diseases of the retina

(2011) Xue Cai   Frontiers in Bioscience-Landmark

DNA repair in organelles: Pathways, organization, regulation, relevance in disease and aging

(2010) Pierre Boesch et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Oxidation and age-related macular degeneration: insights from molecular biology

(2010) Sam Khandhadia et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

The DNA glycosylase Ogg1 defends against oxidant-induced mtDNA damage and apoptosis in pulmonary artery endothelial cells

(2010) Mykhaylo V. Ruchko et al.   FREE RADICAL BIOLOGY AND MEDICINE

Discovery of a Novel Function for Human Rad51

(2010) Jay M. Sage et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The causes of cancer revisited: “Mitochondrial malignancy” and ROS-induced oncogenic transformation – Why mitochondria are targets for cancer therapy

(2010) Stephen J. Ralph et al.   MOLECULAR ASPECTS OF MEDICINE

DNA polymerase structure-based insight on the mutagenic properties of 8-oxoguanine

(2010) William A. Beard et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

The Importance of Mitochondria in Age-Related and Inherited Eye Disorders

(2010) Stuart G. Jarrett et al.   OPHTHALMIC RESEARCH

The critical DNA damage by benzo(a)pyrene in lung tissues of smokers and approaches to preventing its formation

(2010) Kroum Alexandrov et al.   TOXICOLOGY LETTERS

Genotoxic Effects of Carotenoid Breakdown Products in Human Retinal Pigment Epithelial Cells

(2009) Nilesh M. Kalariya et al.   CURRENT EYE RESEARCH

Oxidative Macromolecular Damage in Age-Related Macular Degeneration

(2009) Yüksel Totan et al.   CURRENT EYE RESEARCH

Repair activities of human 8-oxoguanine DNA glycosylase are stimulated by the interaction with human checkpoint sensor Rad9–Rad1–Hus1 complex

(2009) Min Ju Park et al.   DNA REPAIR

Evidence for a role of FEN1 in maintaining mitochondrial DNA integrity

(2009) Lidza Kalifa et al.   DNA REPAIR

Novel DNA mismatch-repair activity involving YB-1 in human mitochondria

(2009) Nadja C. de Souza-Pinto et al.   DNA REPAIR

Membrane association of mitochondrial DNA facilitates base excision repair in mammalian mitochondria

(2009) Pierre Boesch et al.   NUCLEIC ACIDS RESEARCH

Intra- and inter-molecular recombination of mitochondrial DNA after in vivo induction of multiple double-strand breaks

(2009) S. R. Bacman et al.   NUCLEIC ACIDS RESEARCH

Tobacco Smoke: Involvement of Reactive Oxygen Species and Stable Free Radicals in Mechanisms of Oxidative Damage, Carcinogenesis and Synergistic Effects with Other Respirable Particles

(2009) Athanasios Valavanidis et al.   International Journal of Environmental Research and Public Health

Mitochondrial base excision repair of uracil and AP sites takes place by single-nucleotide insertion and long-patch DNA synthesis

(2008) Mansour Akbari et al.   DNA REPAIR

Removal of Oxidative DNA Damage via FEN1-Dependent Long-Patch Base Excision Repair in Human Cell Mitochondria

(2008) P. Liu et al.   MOLECULAR AND CELLULAR BIOLOGY

DNA2 Resolves Expanding Flap in Mitochondrial Base Excision Repair

(2008) William C. Copeland et al.   MOLECULAR CELL

DNA damage and ageing: new-age ideas for an age-old problem

(2008) George A. Garinis et al.   NATURE CELL BIOLOGY

Age-Related Macular Degeneration

(2008) Rama D. Jager et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mitochondrial DNA damage and its potential role in retinal degeneration

(2008) S JARRETT et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Progress and Challenges in Selected Areas of Tobacco Carcinogenesis

(2007) Stephen S. Hecht   CHEMICAL RESEARCH IN TOXICOLOGY