The Role of Nibrin in Doxorubicin-Induced Apoptosis and Cell Senescence in Nijmegen Breakage Syndrome Patients Lymphocytes

Replicatively senescent cells are arrested in G1 and G2 phases

(2016) Zhiyong Mao et al.   Aging-US

The automated FADU-assay, a potential high-throughput in vitro method for early screening of DNA breakage

(2014) María Moreno-Villanueva   ALTEX-Alternatives to Animal Experimentation

A comparison of replicative senescence and doxorubicin-induced premature senescence of vascular smooth muscle cells isolated from human aorta

(2013) Anna Bielak-Zmijewska et al.   BIOGERONTOLOGY

ATM-deficient human fibroblast cells are resistant to low levels of DNA double-strand break induced apoptosis and subsequently undergo drug-induced premature senescence

(2012) Jun Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Nijmegen breakage syndrome (NBS)

(2012) Krystyna H Chrzanowska et al.   Orphanet Journal of Rare Diseases

Oncogenes induce senescence with incomplete growth arrest and suppress the DNA damage response in immortalized cells

(2011) Michael Y. Sherman et al.   AGING CELL

NBS1 deficiency promotes genome instability by affecting DNA damage signaling pathway and impairing telomere integrity

(2011) Yan Yan Hou et al.   CELL BIOCHEMISTRY AND FUNCTION

Cellular senescence and tumor suppressor gene p16

(2011) Hani Rayess et al.   INTERNATIONAL JOURNAL OF CANCER

Impact of cellular senescence signature on ageing research

(2010) Ewa Sikora et al.   AGEING RESEARCH REVIEWS

Telomerase upregulation is a postcrisis event during senescence bypass and immortalization of two Nijmegen breakage syndrome T cell cultures

(2010) Sofie Degerman et al.   AGING CELL

The DNA-dependent protein kinase (DNA-PK): More than just a case of making ends meet?

(2010) Richard Hill et al.   CELL CYCLE

A modified and automated version of the 'Fluorimetric Detection of Alkaline DNA Unwinding' method to quantify formation and repair of DNA strand breaks

(2009) María Moreno-Villanueva et al.   BMC BIOTECHNOLOGY

Telomere uncapping duringin vitroT-lymphocyte senescence

(2008) Amel Chebel et al.   AGING CELL

Induction of senescence with doxorubicin leads to increased genomic instability of HCT116 cells

(2008) Malgorzata A. Sliwinska et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Extreme variation in apoptosis capacity amongst lymphoid cells of Nijmegen breakage syndrome patients

(2007) Nadja Thierfelder et al.   EUROPEAN JOURNAL OF CELL BIOLOGY