Endocrine-disrupting chemicals and the regulation of energy balance

Perinatal BPA exposure alters body weight and composition in a dose specific and sex specific manner: The addition of peripubertal exposure exacerbates adverse effects in female mice

(2017) Beverly S. Rubin et al.   REPRODUCTIVE TOXICOLOGY

Metabolism disrupting chemicals and metabolic disorders

(2017) Jerrold J. Heindel et al.   REPRODUCTIVE TOXICOLOGY

Obesogens: an emerging threat to public health

(2016) Amanda S. Janesick et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Adiponectin, Leptin, and Fatty Acids in the Maintenance of Metabolic Homeostasis through Adipose Tissue Crosstalk

(2016) Jennifer H. Stern et al.   Cell Metabolism

Diminished Phosphorylation of CREB Is a Key Event in the Dysregulation of Gluconeogenesis and Glycogenolysis in PCB126 Hepatotoxicity

(2016) Gopi S. Gadupudi et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Maternal Exposure to Bisphenol-A During Pregnancy Increases Pancreatic β-Cell Growth During Early Life in Male Mice Offspring

(2016) Marta García-Arévalo et al.   ENDOCRINOLOGY

Genomic Effect of Triclosan on the Fetal Hypothalamus: Evidence for Altered Neuropeptide Regulation

(2016) Maria Belen Rabaglino et al.   ENDOCRINOLOGY

U.S. domestic cats as sentinels for perfluoroalkyl substances: Possible linkages with housing, obesity, and disease

(2016) Phillip C. Bost et al.   ENVIRONMENTAL RESEARCH

Polychlorinated biphenyl 126 exposure in L6 myotubes alters glucose metabolism: a pilot study

(2016) Jean-François Mauger et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Benzyl butyl phthalate induces epigenetic stress to enhance adipogenesis in mesenchymal stem cells

(2016) Ravi Sonkar et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Early-life exposure to EDCs: role in childhood obesity and neurodevelopment

(2016) Joseph M. Braun   Nature Reviews Endocrinology

Role of the gut microbiota in host appetite control: bacterial growth to animal feeding behaviour

(2016) Sergueï O. Fetissov   Nature Reviews Endocrinology

Tetrabromobisphenol A and heavy metal exposure via dust ingestion in an e-waste recycling region in Southeast China

(2016) Yuanyuan Wu et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Tributyltin induces mitochondrial fission through Mfn1 degradation in human induced pluripotent stem cells

(2016) Shigeru Yamada et al.   TOXICOLOGY IN VITRO

Perfluorooctane sulfonate (PFOS) exposure could modify the dopaminergic system in several limbic brain regions

(2016) R. Salgado et al.   TOXICOLOGY LETTERS

Adult exposure to tributyltin affects hypothalamic neuropeptide Y, Y1 receptor distribution, and circulating leptin in mice

(2016) E. Bo et al.   Andrology

Inflammation Meets Metabolic Disease: Gut Feeling Mediated by GLP-1

(2016) Tamara Zietek et al.   Frontiers in Immunology

The gut microbiota: a major player in the toxicity of environmental pollutants?

(2016) Sandrine P Claus et al.   npj Biofilms and Microbiomes

Metabolically inert perfluorinated fatty acids directly activate uncoupling protein 1 in brown-fat mitochondria

(2015) Irina G. Shabalina et al.   ARCHIVES OF TOXICOLOGY

Regulation of energy balance by a gut–brain axis and involvement of the gut microbiota

(2015) Paige V. Bauer et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Subchronic Exposure of Mice to Cadmium Perturbs Their Hepatic Energy Metabolism and Gut Microbiome

(2015) Songbin Zhang et al.   CHEMICAL RESEARCH IN TOXICOLOGY

EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals

(2015) A. C. Gore et al.   ENDOCRINE REVIEWS

Bisphenol-A Treatment During Pregnancy in Mice: A New Window of Susceptibility for the Development of Diabetes in Mothers Later in Life

(2015) Paloma Alonso-Magdalena et al.   ENDOCRINOLOGY

Seeds of Toxicity? Erythrocytes and Lead-Associated Kidney Damage

(2015) Julia R. Barrett   ENVIRONMENTAL HEALTH PERSPECTIVES

Developmental Exposure to Aroclor 1254 Alters Migratory Behavior in Juvenile European Starlings (Sturnus vulgaris)

(2015) Leanne M. Flahr et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Changes in glucose metabolism and reversion of genes expression in the liver of insulin-resistant rats exposed to malathion. The protective effects of N-acetylcysteine

(2015) Mohamed Montassar Lasram et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Intestinal Pregnane X Receptor Links Xenobiotic Exposure and Hypercholesterolemia

(2015) Yipeng Sui et al.   MOLECULAR ENDOCRINOLOGY

Endocrine disruptors and obesity

(2015) Jerrold J. Heindel et al.   Nature Reviews Endocrinology

Gene-Environment Interactions Controlling Energy and Glucose Homeostasis and the Developmental Origins of Obesity

(2015) Sebastien Bouret et al.   PHYSIOLOGICAL REVIEWS

The Environmental Pollutants Perfluorooctane Sulfonate and Perfluorooctanoic Acid Upregulate Uncoupling Protein 1 (UCP1) in Brown-Fat Mitochondria Through a UCP1-Dependent Reduction in Food Intake

(2015) Irina G. Shabalina et al.   TOXICOLOGICAL SCIENCES

PCB126-Induced Disruption in Gluconeogenesis and Fatty Acid Oxidation Precedes Fatty Liver in Male Rats

(2015) Gopi S. Gadupudi et al.   TOXICOLOGICAL SCIENCES

BPA-induced DNA hypermethylation of the master mitochondrial gene PGC-1α contributes to cardiomyopathy in male rats

(2015) Ying Jiang et al.   TOXICOLOGY

Arsenic induces structural and compositional colonic microbiome change and promotes host nitrogen and amino acid metabolism

(2015) Rishu Dheer et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The gut microbiota in human energy homeostasis and obesity

(2015) Michael Rosenbaum et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Estrogens and the control of energy homeostasis: a brain perspective

(2015) Miguel López et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Sex-dependent effects of developmental exposure to bisphenol A and ethinyl estradiol on metabolic parameters and voluntary physical activity

(2015) S. A. Johnson et al.   Journal of Developmental Origins of Health and Disease

Type 2 diabetes mellitus

(2015) Ralph A. DeFronzo et al.   Nature Reviews Disease Primers

Polychlorinated Biphenyls Induce Mitochondrial Dysfunction in SH-SY5Y Neuroblastoma Cells

(2015) Stefania Cocco et al.   PLoS One

Dynamic Metabolic Disruption in Rats Perinatally Exposed to Low Doses of Bisphenol-A

(2015) Marie Tremblay-Franco et al.   PLoS One

Chlorinated Persistent Organic Pollutants, Obesity, and Type 2 Diabetes

(2014) Duk-Hee Lee et al.   ENDOCRINE REVIEWS

A Novel Model for Neuroendocrine Toxicology: Neurobehavioral Effects of BPA Exposure in a Prosocial Species, the Prairie Vole (Microtus ochrogaster)

(2014) Alana W. Sullivan et al.   ENDOCRINOLOGY

Food intolerance at adulthood after perinatal exposure to the endocrine disruptor bisphenol A

(2014) Sandrine Menard et al.   FASEB JOURNAL

Environmental chemicals targeting thyroid

(2014) Thomas Zoeller   Hormones-International Journal of Endocrinology and Metabolism

Perinatal exposure to bisphenol A exacerbates nonalcoholic steatohepatitis-like phenotype in male rat offspring fed on a high-fat diet

(2014) Jie Wei et al.   JOURNAL OF ENDOCRINOLOGY

Transgenerational inheritance of prenatal obesogen exposure

(2014) Amanda S. Janesick et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Sex-specific enhanced behavioral toxicity induced by maternal exposure to a mixture of low dose endocrine-disrupting chemicals

(2014) Marissa Sobolewski et al.   NEUROTOXICOLOGY

Adipogenic Effects of a Combination of the Endocrine-Disrupting Compounds Bisphenol A, Diethylhexylphthalate, and Tributyltin

(2014) Ronald Biemann et al.   Obesity Facts

Exposure to Bisphenol-A during Pregnancy Partially Mimics the Effects of a High-Fat Diet Altering Glucose Homeostasis and Gene Expression in Adult Male Mice

(2014) Marta García-Arevalo et al.   PLoS One

Exposure to a Northern Contaminant Mixture (NCM) Alters Hepatic Energy and Lipid Metabolism Exacerbating Hepatic Steatosis in Obese JCR Rats

(2014) Ryan J. Mailloux et al.   PLoS One

Perinatal Exposure of Mice to the Pesticide DDT Impairs Energy Expenditure and Metabolism in Adult Female Offspring

(2014) Michele La Merrill et al.   PLoS One

Halogenated Bisphenol-A Analogs Act as Obesogens in Zebrafish Larvae (Danio rerio)

(2014) Anne Riu et al.   TOXICOLOGICAL SCIENCES

Programming of metabolic effects in C57BL/6JxFVB mice by exposure to bisphenol A during gestation and lactation

(2014) J.C.J. van Esterik et al.   TOXICOLOGY

F0 maternal BPA exposure induced glucose intolerance of F2 generation through DNA methylation change in Gck

(2014) Gengqi Li et al.   TOXICOLOGY LETTERS

Chronic exposure of mice to environmental endocrine-disrupting chemicals disturbs their energy metabolism

(2014) Yuanxiang Jin et al.   TOXICOLOGY LETTERS

Mitochondrial dysfunction in early life resulted from perinatal bisphenol A exposure contributes to hepatic steatosis in rat offspring

(2014) Ying Jiang et al.   TOXICOLOGY LETTERS

Evolutionary Perspectives on the Obesity Epidemic: Adaptive, Maladaptive, and Neutral Viewpoints

(2013) John R. Speakman   Annual Review of Nutrition

Adipocytes under assault: Environmental disruption of adipose physiology

(2013) Shane M. Regnier et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Environmental Chemicals and Type 2 Diabetes: An Updated Systematic Review of the Epidemiologic Evidence

(2013) Chin-Chi Kuo et al.   Current Diabetes Reports

Hepatic DNA methylation modifications in early development of rats resulting from perinatal BPA exposure contribute to insulin resistance in adulthood

(2013) Y. Ma et al.   DIABETOLOGIA

Organizational Effects of Perinatal Exposure to Bisphenol-A and Diethylstilbestrol on Arcuate Nucleus Circuitry Controlling Food Intake and Energy Expenditure in Male and Female CD-1 Mice

(2013) Harry MacKay et al.   ENDOCRINOLOGY

Exercise Attenuates PCB-Induced Changes in the Mouse Gut Microbiome

(2013) Jeong June Choi et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Effect of Bisphenol-A on insulin signal transduction and glucose oxidation in liver of adult male albino rat

(2013) Shankar Jayashree et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Perinatal bisphenol A exposure promotes hyperactivity, lean body composition, and hormonal responses across the murine life course

(2013) Olivia S. Anderson et al.   FASEB JOURNAL

Polychlorinated biphenyl 153 is a diet-dependent obesogen that worsens nonalcoholic fatty liver disease in male C57BL6/J mice

(2013) Banrida Wahlang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Prolonged exposure to a low-dose of bisphenol A increases spontaneous motor activity in adult male rats

(2013) Kazuo Nojima et al.   Journal of Physiological Sciences

The Endocrine Disrupting Chemical Tolylfluanid Alters Adipocyte Metabolism via Glucocorticoid Receptor Activation

(2013) Brian A. Neel et al.   MOLECULAR ENDOCRINOLOGY

Dynamic Postnatal Developmental and Sex-Specific Neuroendocrine Effects of Prenatal Polychlorinated Biphenyls in rats

(2013) Deena M. Walker et al.   MOLECULAR ENDOCRINOLOGY

Prenatal exposure to bisphenol A impacts midbrain dopamine neurons and hippocampal spine synapses in non-human primates

(2013) John D. Elsworth et al.   NEUROTOXICOLOGY

Bisphenol A Impairs Hepatic Glucose Sensing in C57BL/6 Male Mice

(2013) Leigh Perreault et al.   PLoS One

Bisphenol-A Impairs Insulin Action and Up-Regulates Inflammatory Pathways in Human Subcutaneous Adipocytes and 3T3-L1 Cells

(2013) Rossella Valentino et al.   PLoS One

Metabolic disruption in male mice due to fetal exposure to low but not high doses of bisphenol A (BPA): Evidence for effects on body weight, food intake, adipocytes, leptin, adiponectin, insulin and glucose regulation

(2013) Brittany M. Angle et al.   REPRODUCTIVE TOXICOLOGY

Perfluorinated Compounds in Relation to Birth Weight in the Norwegian Mother and Child Cohort Study

(2012) Kristina W. Whitworth et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Protective role of Lycopene against Aroclor 1254-induced changes on GLUT4 in the skeletal muscles of adult male rat

(2012) Anne Augustine Williams et al.   DRUG AND CHEMICAL TOXICOLOGY

Endocrine-Disrupting Chemicals and Public Health Protection: A Statement of Principles from The Endocrine Society

(2012) R. Thomas Zoeller et al.   ENDOCRINOLOGY

Effects of Di(2-ethylhexyl) Phthalate (DEHP) on Female Fertility and Adipogenesis in C3H/N Mice

(2012) Juliane-Susanne Schmidt et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Impact of chronic exposure to low doses of chlorpyrifos on the intestinal microbiota in the Simulator of the Human Intestinal Microbial Ecosystem (SHIME®) and in the rat

(2012) Claire Joly et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Lactational exposure to hydroxylated polychlorinated biphenyl (OH-PCB 106) causes hyperactivity in male rat pups by aberrant increase in dopamine and its receptor

(2012) Ronny Lesmana et al.   ENVIRONMENTAL TOXICOLOGY

Short-Term Treatment with Bisphenol-A Leads to Metabolic Abnormalities in Adult Male Mice

(2012) Thiago M. Batista et al.   PLoS One

TCDD-Elicited Effects on Liver, Serum, and Adipose Lipid Composition in C57BL/6 Mice

(2012) Michelle Manente Angrish et al.   TOXICOLOGICAL SCIENCES

Neurodevelopmental and behavioral toxicity via lactational exposure to the sum of six indicator non-dioxin-like-polychlorinated biphenyls (∑6 NDL-PCBs) in mice

(2012) Arpiné Ardzivian Elnar et al.   TOXICOLOGY

Gender differential effects of developmental exposure to methyl-mercury, polychlorinated biphenyls 126 or 153, or its combinations on motor activity and coordination

(2012) Omar Cauli et al.   TOXICOLOGY

Low concentrations of bisphenol A induce lipid accumulation mediated by the production of reactive oxygen species in the mitochondria of HepG2 cells

(2012) Laurence Huc et al.   TOXICOLOGY IN VITRO

Endocrine Disruptors: From Endocrine to Metabolic Disruption

(2011) Cristina Casals-Casas et al.   Annual Review of Physiology

Endocrine disrupting chemicals affect the adipogenic differentiation of mesenchymal stem cells in distinct ontogenetic windows

(2011) Ronald Biemann et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Paradox of Progress: Environmental Disruption of Metabolism and the Diabetes Epidemic

(2011) B. A. Neel et al.   DIABETES

Perinatal Exposure to Bisphenol A at Reference Dose Predisposes Offspring to Metabolic Syndrome in Adult Rats on a High-Fat Diet

(2011) Jie Wei et al.   ENDOCRINOLOGY

Peroxisome Proliferator-Activated Receptor γ Is a Target for Halogenated Analogs of Bisphenol A

(2011) Anne Riu et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Do Interactions Between Gut Ecology and Environmental Chemicals Contribute to Obesity and Diabetes?

(2011) Suzanne M. Snedeker et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Low doses of bisphenol a induce gene expression related to lipid synthesis and trigger triglyceride accumulation in adult mouse liver

(2011) Alice Marmugi et al.   HEPATOLOGY

Minireview: PPARγ as the target of obesogens

(2011) Amanda Janesick et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Endocrine disruptors in the etiology of type 2 diabetes mellitus

(2011) Paloma Alonso-Magdalena et al.   Nature Reviews Endocrinology

Chronic Consumption of Farmed Salmon Containing Persistent Organic Pollutants Causes Insulin Resistance and Obesity in Mice

(2011) Mohammad Madani Ibrahim et al.   PLoS One

Subchronic Polychlorinated Biphenyl (Aroclor 1254) Exposure Produces Oxidative Damage and Neuronal Death of Ventral Midbrain Dopaminergic Systems

(2011) Donna W. Lee et al.   TOXICOLOGICAL SCIENCES

Characterization of Novel Ligands of ERα, Erβ, and PPARγ: The Case of Halogenated Bisphenol A and Their Conjugated Metabolites

(2011) Anne Riu et al.   TOXICOLOGICAL SCIENCES

Bisphenol A Exposure during Pregnancy Disrupts Glucose Homeostasis in Mothers and Adult Male Offspring

(2010) Paloma Alonso-Magdalena et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

A Novel Role for the Dioxin Receptor in Fatty Acid Metabolism and Hepatic Steatosis

(2010) Jung Hoon Lee et al.   GASTROENTEROLOGY

Identification of the Aryl Hydrocarbon Receptor Target GeneTiPARPas a Mediator of Suppression of Hepatic Gluconeogenesis by 2,3,7,8-Tetrachlorodibenzo-p-dioxin and of Nicotinamide as a Corrective Agent for This Effect

(2010) Silvia Diani-Moore et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Disruption of thyroid hormone-dependent hypothalamic set-points by environmental contaminants

(2010) Stéphanie Decherf et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Environmental causes of cancer: endocrine disruptors as carcinogens

(2010) Ana M. Soto et al.   Nature Reviews Endocrinology

Prenatal Exposure to PFOS or PFOA Alters Motor Function in Mice in a Sex-Related Manner

(2010) Natalia Onishchenko et al.   NEUROTOXICITY RESEARCH

Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis

(2010) Shijie Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exposure of neonatal female rats to bisphenol A disrupts hypothalamic LHRH pre-mRNA processing and estrogen receptor alpha expression in nuclei controlling estrous cyclicity

(2010) L. Monje et al.   REPRODUCTIVE TOXICOLOGY

Polycyclic aromatic hydrocarbons potentiate high-fat diet effects on intestinal inflammation

(2010) Ayman Khalil et al.   TOXICOLOGY LETTERS

Perinatal Exposure to Bisphenol A Alters Early Adipogenesis in the Rat

(2009) Emmanuel Somm et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

The Pollutant Diethylhexyl Phthalate Regulates Hepatic Energy Metabolism via Species-Specific PPARα-Dependent Mechanisms

(2009) Jérôme N. Feige et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Toxicant-associated steatohepatitis in vinyl chloride workers

(2009) Matt Cave et al.   HEPATOLOGY

Aryl hydrocarbon receptor-mediated effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on glucose-stimulated insulin secretion in mice

(2009) Hisaka Kurita et al.   JOURNAL OF APPLIED TOXICOLOGY

Interpreting endocrine disruption from an integrative biology perspective

(2009) Ana M. Soto et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Environmental estrogens and obesity

(2009) Retha R. Newbold et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Phenotypic dichotomy following developmental exposure to perfluorooctanoic acid (PFOA) in female CD-1 mice: Low doses induce elevated serum leptin and insulin, and overweight in mid-life☆

(2009) Erin P. Hines et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Endocrine disrupters as obesogens

(2009) Felix Grün et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The pancreatic β-cell as a target of estrogens and xenoestrogens: Implications for blood glucose homeostasis and diabetes

(2009) Angel Nadal et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Impact of oral bisphenol A at reference doses on intestinal barrier function and sex differences after perinatal exposure in rats

(2009) V. Braniste et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fetal and neonatal exposure to three typical environmental chemicals with different mechanisms of action: Mixed exposure to phenol, phthalate, and dioxin cancels the effects of sole exposure on mouse midbrain dopaminergic nuclei

(2009) Takashi Tanida et al.   TOXICOLOGY LETTERS

Bisphenol A at Environmentally Relevant Doses Inhibits Adiponectin Release from Human Adipose Tissue Explants and Adipocytes

(2008) Eric R. Hugo et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Deficits in development of synaptic plasticity in rat dorsal striatum following prenatal and neonatal exposure to low-dose bisphenol A

(2008) R. Zhou et al.   NEUROSCIENCE

Low-dose dioxins alter gene expression related to cholesterol biosynthesis, lipogenesis, and glucose metabolism through the aryl hydrocarbon receptor-mediated pathway in mouse liver

(2008) Shoko Sato et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Exposure of the U.S. Population to Bisphenol A and 4- tertiary -Octylphenol: 2003–2004

(2007) Antonia M. Calafat et al.   ENVIRONMENTAL HEALTH PERSPECTIVES