Gene-Environment Interactions Controlling Energy and Glucose Homeostasis and the Developmental Origins of Obesity

Neonatal Insulin Action Impairs Hypothalamic Neurocircuit Formation in Response to Maternal High-Fat Feeding

(2014) Merly C. Vogt et al.   CELL

Human adipose dynamics and metabolic health

(2013) Bin Feng et al.   Annals of the New York Academy of Sciences

Islet β cell mass in diabetes and how it relates to function, birth, and death

(2013) Gordon C. Weir et al.   Annals of the New York Academy of Sciences

Tanycytic VEGF-A Boosts Blood-Hypothalamus Barrier Plasticity and Access of Metabolic Signals to the Arcuate Nucleus in Response to Fasting

(2013) Fanny Langlet et al.   Cell Metabolism

FAT/CD36: A Major Regulator of Neuronal Fatty Acid Sensing and Energy Homeostasis in Rats and Mice

(2013) Christelle Le Foll et al.   DIABETES

Maternal Obesity Enhances White Adipose Tissue Differentiation and Alters Genome-Scale DNA Methylation in Male Rat Offspring

(2013) Sarah J. Borengasser et al.   ENDOCRINOLOGY

Paternal obesity initiates metabolic disturbances in two generations of mice with incomplete penetrance to the F2 generation and alters the transcriptional profile of testis and sperm microRNA content

(2013) Tod Fullston et al.   FASEB JOURNAL

Rare variants in single-minded 1 (SIM1) are associated with severe obesity

(2013) Shwetha Ramachandrappa et al.   JOURNAL OF CLINICAL INVESTIGATION

AMPK, insulin resistance, and the metabolic syndrome

(2013) Neil B. Ruderman et al.   JOURNAL OF CLINICAL INVESTIGATION

Inflammation as a potential link between nonalcoholic fatty liver disease and insulin resistance

(2013) Mohamed Asrih et al.   JOURNAL OF ENDOCRINOLOGY

Ectopic lipid storage and insulin resistance: a harmful relationship

(2013) J. Borén et al.   JOURNAL OF INTERNAL MEDICINE

Paternal Stress Exposure Alters Sperm MicroRNA Content and Reprograms Offspring HPA Stress Axis Regulation

(2013) A. B. Rodgers et al.   JOURNAL OF NEUROSCIENCE

Differential methylation in glucoregulatory genes of offspring born before vs. after maternal gastrointestinal bypass surgery

(2013) F. Guenard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice

(2013) V. K. Ridaura et al.   SCIENCE

Neuronal circuits that regulate feeding behavior and metabolism

(2013) Jong-Woo Sohn et al.   TRENDS IN NEUROSCIENCES

Development of the Hypothalamic Melanocortin System

(2013) Berengere Coupe et al.   Frontiers in Endocrinology

Regulation of Insulin Secretion in Human Pancreatic Islets

(2012) Patrik Rorsman et al.   Annual Review of Physiology

GABAergic RIP-Cre Neurons in the Arcuate Nucleus Selectively Regulate Energy Expenditure

(2012) Dong Kong et al.   CELL

Hindbrain Neurons as an Essential Hub in the Neuroanatomically Distributed Control of Energy Balance

(2012) Harvey J. Grill et al.   Cell Metabolism

Acute Exercise Remodels Promoter Methylation in Human Skeletal Muscle

(2012) Romain Barrès et al.   Cell Metabolism

Associations of Maternal Prepregnancy Body Mass Index and Gestational Weight Gain With Adult Offspring Cardiometabolic Risk Factors

(2012) Hagit Hochner et al.   CIRCULATION

Sensitive period in flavor learning: Effects of duration of exposure to formula flavors on food likes during infancy

(2012) Julie A. Mennella et al.   CLINICAL NUTRITION

Non-alcoholic fatty liver disease and insulin resistance: From bench to bedside

(2012) K. Gariani et al.   DIABETES & METABOLISM

Embryonic Birthdate of Hypothalamic Leptin-Activated Neurons in Mice

(2012) Yuko Ishii et al.   ENDOCRINOLOGY

Epigenetics: The missing link to understanding β-cell dysfunction in the pathogenesis of type 2 diabetes

(2012) Elizabeth R. Gilbert et al.   Epigenetics

The impact of neonatal breast-feeding on growth trajectories of youth exposed and unexposed to diabetes in utero: the EPOCH Study

(2012) T L Crume et al.   INTERNATIONAL JOURNAL OF OBESITY

Effect of intrauterine growth retardation on liver and long-term metabolic risk

(2012) S Cianfarani et al.   INTERNATIONAL JOURNAL OF OBESITY

Prevalence of Obesity and Trends in Body Mass Index Among US Children and Adolescents, 1999-2010

(2012) Cynthia L. Ogden et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Direct leptin action on POMC neurons regulates glucose homeostasis and hepatic insulin sensitivity in mice

(2012) Eric D. Berglund et al.   JOURNAL OF CLINICAL INVESTIGATION

Human SH2B1 mutations are associated with maladaptive behaviors and obesity

(2012) Michael E. Doche et al.   JOURNAL OF CLINICAL INVESTIGATION

Nature, nurture or nutrition? Impact of maternal nutrition on maternal care, offspring development and reproductive function

(2012) K. L. Connor et al.   JOURNAL OF PHYSIOLOGY-LONDON

Tanycytes of the hypothalamic median eminence form a diet-responsive neurogenic niche

(2012) Daniel A Lee et al.   NATURE NEUROSCIENCE

Hindbrain Ghrelin Receptor Signaling Is Sufficient to Maintain Fasting Glucose

(2012) Michael M. Scott et al.   PLoS One

Role of intramyocelluar lipids in human health

(2012) Paul M. Coen et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Beyond the fourth wave of genome-wide obesity association studies

(2012) C H Sandholt et al.   Nutrition & Diabetes

Role of ghrelin in food reward: impact of ghrelin on sucrose self-administration and mesolimbic dopamine and acetylcholine receptor gene expression

(2011) Karolina P. Skibicka et al.   ADDICTION BIOLOGY

Chronic reduction of insulin receptors in the ventromedial hypothalamus produces glucose intolerance and islet dysfunction in the absence of weight gain

(2011) Sachin A. Paranjape et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Food reward, hyperphagia, and obesity

(2011) Hans-Rudolf Berthoud et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Maternal Obesity-Impaired Insulin Signaling in Sheep and Induced Lipid Accumulation and Fibrosis in Skeletal Muscle of Offspring1

(2011) Xu Yan et al.   BIOLOGY OF REPRODUCTION

Leptin Action via Neurotensin Neurons Controls Orexin, the Mesolimbic Dopamine System and Energy Balance

(2011) Gina M. Leinninger et al.   Cell Metabolism

Changes in the Prevalence of the Most Common Causes of Chronic Liver Diseases in the United States From 1988 to 2008

(2011) Zobair M. Younossi et al.   Clinical Gastroenterology and Hepatology

Postnatal Growth and DNA Methylation Are Associated With Differential Gene Expression of the TACSTD2 Gene and Childhood Fat Mass

(2011) A. Groom et al.   DIABETES

Epigenetic Gene Promoter Methylation at Birth Is Associated With Child's Later Adiposity

(2011) K. M. Godfrey et al.   DIABETES

Set points, settling points and some alternative models: theoretical options to understand how genes and environments combine to regulate body adiposity

(2011) J. R. Speakman et al.   Disease Models & Mechanisms

Maternal Diabetes Compromises the Organization of Hypothalamic Feeding Circuits and Impairs Leptin Sensitivity in Offspring

(2011) Sophie M. Steculorum et al.   ENDOCRINOLOGY

Metabolic Sensing and the Brain: Who, What, Where, and How?

(2011) Barry E. Levin et al.   ENDOCRINOLOGY

Genome-wide survey reveals predisposing diabetes type 2-related DNA methylation variations in human peripheral blood

(2011) Gidon Toperoff et al.   HUMAN MOLECULAR GENETICS

Maternal body mass index and the risk of fetal and infant death: a cohort study from the North of England

(2011) P. W. G. Tennant et al.   HUMAN REPRODUCTION

Inverse relation of body weight and weight change with mortality and morbidity in patients with type 2 diabetes and cardiovascular co-morbidity: An analysis of the PROactive study population

(2011) Wolfram Doehner et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Prenatal and postnatal programming of body composition in obese children and adolescents: evidence from anthropometry, DXA and the 4-component model

(2011) J C K Wells et al.   INTERNATIONAL JOURNAL OF OBESITY

Peripheral glucose homeostasis: does brain insulin matter?

(2011) Barry E. Levin et al.   JOURNAL OF CLINICAL INVESTIGATION

Ghrelin mediates stress-induced food-reward behavior in mice

(2011) Jen-Chieh Chuang et al.   JOURNAL OF CLINICAL INVESTIGATION

Brain insulin action augments hepatic glycogen synthesis without suppressing glucose production or gluconeogenesis in dogs

(2011) Christopher J. Ramnanan et al.   JOURNAL OF CLINICAL INVESTIGATION

Remodeling of the arcuate nucleus energy-balance circuit is inhibited in obese mice

(2011) David E.G. McNay et al.   JOURNAL OF CLINICAL INVESTIGATION

Functional implications of limited leptin receptor and ghrelin receptor coexpression in the brain

(2011) Mario Perello et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Single KATP Channel Opening in Response to Action Potential Firing in Mouse Dentate Granule Neurons

(2011) G. R. Tanner et al.   JOURNAL OF NEUROSCIENCE

Low Maternal Vitamin B-12 Status Is Associated with Offspring Insulin Resistance Regardless of Antenatal Micronutrient Supplementation in Rural Nepal

(2011) Christine P. Stewart et al.   JOURNAL OF NUTRITION

Gut microbiota, epithelial function and derangements in obesity

(2011) Helen E. Raybould   JOURNAL OF PHYSIOLOGY-LONDON

Epigenetic mechanisms elicited by nutrition in early life

(2011) Roberto Berni Canani et al.   NUTRITION RESEARCH REVIEWS

Four-Year Weight Losses in the Look AHEAD Study: Factors Associated With Long-Term Success

(2011) Thomas A. Wadden et al.   Obesity

Developmental effects of ghrelin

(2011) Sophie M. Steculorum et al.   PEPTIDES

Development of Posterior Hypothalamic Neurons Enlightens a Switch in the Prosencephalic Basic Plan

(2011) Sophie Croizier et al.   PLoS One

Maternal diet and aging alter the epigenetic control of a promoter-enhancer interaction at the Hnf4a gene in rat pancreatic islets

(2011) I. Sandovici et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transplanted Hypothalamic Neurons Restore Leptin Signaling and Ameliorate Obesity in db/db Mice

(2011) A. Czupryn et al.   SCIENCE

Prenatal stress and developmental programming of human health and disease risk: concepts and integration of empirical findings

(2011) Sonja Entringer et al.   Current Opinion in Endocrinology Diabetes and Obesity

Developmental Programming in Response to Maternal Overnutrition

(2011) Maria Z. Alfaradhi et al.   Frontiers in Genetics

Weight gain in pregnancy and childhood body composition: findings from the Southampton Women’s Survey

(2010) Sarah R Crozier et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Comparing maternal and paternal intergenerational transmission of obesity risk in a large population-based sample

(2010) Katriina L Whitaker et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Nutrition in infancy and long-term risk of obesity: evidence from 2 randomized controlled trials

(2010) Atul Singhal et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Relation of Immediate Postnatal Growth With Obesity and Related Metabolic Risk Factors in Adulthood: The Northern Finland Birth Cohort 1966 Study

(2010) I. Tzoulaki et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Hypothalamic Nitric Oxide in Hypoglycemia Detection and Counterregulation: A Two-Edged Sword

(2010) Xavier Fioramonti et al.   ANTIOXIDANTS & REDOX SIGNALING

Transitional change in rat fetal cell proliferation in response to ghrelin and des-acyl ghrelin during the last stage of pregnancy

(2010) Yoshiyuki Inoue et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Interaction of perinatal and pre-pubertal factors with genetic predisposition in the development of neural pathways involved in the regulation of energy homeostasis

(2010) Barry E. Levin   BRAIN RESEARCH

Neurodevelopmental actions of leptin

(2010) Sebastien G. Bouret   BRAIN RESEARCH

Paternally Induced Transgenerational Environmental Reprogramming of Metabolic Gene Expression in Mammals

(2010) Benjamin R. Carone et al.   CELL

Endogenous Leptin Signaling in the Caudal Nucleus Tractus Solitarius and Area Postrema Is Required for Energy Balance Regulation

(2010) Matthew R. Hayes et al.   Cell Metabolism

The Medial Amygdalar Nucleus: A Novel Glucose-Sensing Region That Modulates the Counterregulatory Response to Hypoglycemia

(2010) L. Zhou et al.   DIABETES

Exposure to the Chinese Famine in Early Life and the Risk of Hyperglycemia and Type 2 Diabetes in Adulthood

(2010) Y. Li et al.   DIABETES

Brain lipid sensing and nervous control of energy balance

(2010) S. Migrenne et al.   DIABETES & METABOLISM

Insulin promoter DNA methylation correlates negatively with insulin gene expression and positively with HbA1c levels in human pancreatic islets

(2010) B. T. Yang et al.   DIABETOLOGIA

Epigenetic Changes in the Hypothalamic Proopiomelanocortin and Glucocorticoid Receptor Genes in the Ovine Fetus after Periconceptional Undernutrition

(2010) Adam Stevens et al.   ENDOCRINOLOGY

Corticosterone Regulates Synaptic Input Organization of POMC and NPY/AgRP Neurons in Adult Mice

(2010) Erika Gyengesi et al.   ENDOCRINOLOGY

Large Litter Rearing Enhances Leptin Sensitivity and Protects Selectively Bred Diet-Induced Obese Rats from Becoming Obese

(2010) Christa M. Patterson et al.   ENDOCRINOLOGY

Maternal High-Fat Diet Alters Methylation and Gene Expression of Dopamine and Opioid-Related Genes

(2010) Zivjena Vucetic et al.   ENDOCRINOLOGY

Early Overnutrition Results in Early-Onset Arcuate Leptin Resistance and Increased Sensitivity to High-Fat Diet

(2010) Maria M. Glavas et al.   ENDOCRINOLOGY

Genes and lifestyle factors in obesity: results from 12 462 subjects from MONICA/KORA

(2010) C Holzapfel et al.   INTERNATIONAL JOURNAL OF OBESITY

Use of self-reported height and weight biases the body mass index–mortality association

(2010) S W Keith et al.   INTERNATIONAL JOURNAL OF OBESITY

The impact of perinatal probiotic intervention on the development of overweight and obesity: follow-up study from birth to 10 years

(2010) R Luoto et al.   INTERNATIONAL JOURNAL OF OBESITY

Adaptive thermogenesis in humans

(2010) M Rosenbaum et al.   INTERNATIONAL JOURNAL OF OBESITY

Prevalence and Trends in Obesity Among US Adults, 1999-2008

(2010) Katherine M. Flegal   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Cut-like Homeobox 1 (CUX1) Regulates Expression of the Fat Mass and Obesity-associated and Retinitis Pigmentosa GTPase Regulator-interacting Protein-1-like (RPGRIP1L) Genes and Coordinates Leptin Receptor Signaling

(2010) George Stratigopoulos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Maternal BMI, Parity, and Pregnancy Weight Gain: Influences on Offspring Adiposity in Young Adulthood

(2010) R. M. Reynolds et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

ATP-Sensitive Potassium Channel-Mediated Lactate Effect on Orexin Neurons: Implications for Brain Energetics during Arousal

(2010) M. P. Parsons et al.   JOURNAL OF NEUROSCIENCE

De Novo Neurogenesis in Adult Hypothalamus as a Compensatory Mechanism to Regulate Energy Balance

(2010) A. A. Pierce et al.   JOURNAL OF NEUROSCIENCE

Role of Early Hormonal and Nutritional Experiences in Shaping Feeding Behavior and Hypothalamic Development

(2010) Sebastien G. Bouret   JOURNAL OF NUTRITION

Maternal Zinc Deficiency in Rats Affects Growth and Glucose Metabolism in the Offspring by Inducing Insulin Resistance Postnatally

(2010) Ming-Yu Jou et al.   JOURNAL OF NUTRITION

Epigenetic malprogramming of the insulin receptor promoter due to developmental overfeeding

(2010) Andreas Plagemann et al.   JOURNAL OF PERINATAL MEDICINE

Epigenetic modification of fetal baboon hepatic phosphoenolpyruvate carboxykinase following exposure to moderately reduced nutrient availability

(2010) Mark J. Nijland et al.   JOURNAL OF PHYSIOLOGY-LONDON

RAPID REPORT: Dietary intervention prior to pregnancy reverses metabolic programming in male offspring of obese rats

(2010) E. Zambrano et al.   JOURNAL OF PHYSIOLOGY-LONDON

Direct and indirect control of orexin/hypocretin neurons by glycine receptors

(2010) Mahesh M. Karnani et al.   JOURNAL OF PHYSIOLOGY-LONDON

Chronic high-fat diet in fathers programs β-cell dysfunction in female rat offspring

(2010) Sheau-Fang Ng et al.   NATURE

Pomc-expressing progenitors give rise to antagonistic neuronal populations in hypothalamic feeding circuits

(2010) Stephanie L Padilla et al.   NATURE MEDICINE

The arcuate nucleus as a circumventricular organ in the mouse

(2010) Philippe Ciofi   NEUROSCIENCE LETTERS

Obesity and Mortality in African-Americans

(2010) June Stevens   NUTRITION REVIEWS

Variations in BMI and Prevalence of Health Risks in Diverse Racial and Ethnic Populations

(2010) Manfred Stommel et al.   Obesity

Cytosine Methylation Dysregulation in Neonates Following Intrauterine Growth Restriction

(2010) Francine Einstein et al.   PLoS One

Integrated Genetic and Epigenetic Analysis Identifies Haplotype-Specific Methylation in the FTO Type 2 Diabetes and Obesity Susceptibility Locus

(2010) Christopher G. Bell et al.   PLoS One

Synaptic input organization of the melanocortin system predicts diet-induced hypothalamic reactive gliosis and obesity

(2010) T. L. Horvath et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Excess Body Weight and Incidence of Stroke

(2010) Pasquale Strazzullo et al.   STROKE

The emerging genetics of type 2 diabetes

(2010) Amélie Bonnefond et al.   TRENDS IN MOLECULAR MEDICINE

Early nutritional environment: focus on health effects of microbiota and probiotics

(2010) K. Laitinen et al.   Beneficial Microbes

Obesity genes identified in genome-wide association studies are associated with adiposity measures and potentially with nutrient-specific food preference

(2009) Florianne Bauer et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Perinatal risk factors for childhood obesity and metabolic dysregulation

(2009) Patrick M Catalano et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Lower protein in infant formula is associated with lower weight up to age 2 y: a randomized clinical trial

(2009) et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Effects of maternal genotype and diet on offspring glucose and fatty acid-sensing ventromedial hypothalamic nucleus neurons

(2009) Christelle Le Foll et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Three weeks of postweaning exercise in DIO rats produces prolonged increases in central leptin sensitivity and signaling

(2009) Christa M. Patterson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Characteristics and mechanisms of hypothalamic neuronal fatty acid sensing

(2009) Christelle Le Foll et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Hypothalamic nutrient sensing in the control of energy homeostasis

(2009) Clémence Blouet et al.   BEHAVIOURAL BRAIN RESEARCH

Ghrelin Increases the Rewarding Value of High-Fat Diet in an Orexin-Dependent Manner

(2009) Mario Perello et al.   BIOLOGICAL PSYCHIATRY

The incidence of co-morbidities related to obesity and overweight: A systematic review and meta-analysis

(2009) Daphne P Guh et al.   BMC PUBLIC HEALTH

Programming of growth, insulin resistance and vascular dysfunction in offspring of late gestation diabetic rats

(2009) Emily M. Segar et al.   CLINICAL SCIENCE

Lifestyle factors and colorectal cancer risk (1): systematic review and meta-analysis of associations with body mass index

(2009) D. J. Harriss et al.   Colorectal Disease

Prenatal Stress and Neurodevelopment of the Child: Focus on the HPA Axis and Role of the Placenta

(2009) K. O’Donnell et al.   DEVELOPMENTAL NEUROSCIENCE

Chronic Maternal Dietary Chromium Restriction Modulates Visceral Adiposity: Probable Underlying Mechanisms

(2009) I. J.N. Padmavathi et al.   DIABETES

Prenatal Stress or High-Fat Diet Increases Susceptibility to Diet-Induced Obesity in Rat Offspring

(2009) K. L.K. Tamashiro et al.   DIABETES

Maternal High-Fat Diet Promotes Body Length Increases and Insulin Insensitivity in Second-Generation Mice

(2009) Gregory A. Dunn et al.   ENDOCRINOLOGY

Nutritional Programming Affects Hypothalamic Organization and Early Response to Leptin

(2009) Bérengère Coupé et al.   ENDOCRINOLOGY

The obesity paradox: weighing the benefit

(2009) W. Doehner et al.   EUROPEAN HEART JOURNAL

Normal weight obesity: a risk factor for cardiometabolic dysregulation and cardiovascular mortality

(2009) Abel Romero-Corral et al.   EUROPEAN HEART JOURNAL

Lifelong Enhanced Diabetes Susceptibility and Obesity after Temporary Intrahypothalamic Hyperinsulinism during Brain Organization

(2009) A. Plagemann et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Obesity and Enhanced Diabetes and Cardiovascular Risk in Adult Rats due to Early Postnatal Overfeeding

(2009) A. Plagemann et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Maternal high-fat feeding primes steatohepatitis in adult mice offspring, involving mitochondrial dysfunction and altered lipogenesis gene expression

(2009) Kimberley D. Bruce et al.   HEPATOLOGY

Replication and extension of genome-wide association study results for obesity in 4923 adults from northern Sweden

(2009) Frida Renström et al.   HUMAN MOLECULAR GENETICS

DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific

(2009) Elmar W. Tobi et al.   HUMAN MOLECULAR GENETICS

Common variants near MC4R in relation to body fat, body fat distribution, metabolic traits and energy expenditure

(2009) S I I Kring et al.   INTERNATIONAL JOURNAL OF OBESITY

Overweight in midlife and risk of dementia: a 40-year follow-up study

(2009) L B Hassing et al.   INTERNATIONAL JOURNAL OF OBESITY

Effects of Maternal Surgical Weight Loss in Mothers on Intergenerational Transmission of Obesity

(2009) J. Smith et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Leptin targets in the mouse brain

(2009) Michael M. Scott et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Distribution of leptin-sensitive cells in the postnatal and adult mouse brain

(2009) Emilie Caron et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population

(2009) Kikuko Hotta et al.   JOURNAL OF HUMAN GENETICS

Oleic Acid Directly Regulates POMC Neuron Excitability in the Hypothalamus

(2009) Young-Hwan Jo et al.   JOURNAL OF NEUROPHYSIOLOGY

Relationship among Brain and Blood Glucose Levels and Spontaneous and Glucoprivic Feeding

(2009) A. A. Dunn-Meynell et al.   JOURNAL OF NEUROSCIENCE

Changes in visceral adipose tissue mitochondrial content with type 2 diabetes and daily voluntary wheel running in OLETF rats

(2009) Matthew J. Laye et al.   JOURNAL OF PHYSIOLOGY-LONDON

Hypothalamic proopiomelanocortin promoter methylation becomes altered by early overfeeding: an epigenetic model of obesity and the metabolic syndrome

(2009) Andreas Plagemann et al.   JOURNAL OF PHYSIOLOGY-LONDON

Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies

(2009) Prospective Studies Collaboration   LANCET

Adipose tissue as an endocrine organ

(2009) Sandra Galic et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Human genetics illuminates the paths to metabolic disease

(2009) Stephen O’Rahilly   NATURE

Novel Obesity Risk Loci Do Not Determine Distribution of Body Fat Depots: A Whole-body MRI/MRS study

(2009) Axel Haupt et al.   Obesity

Maternal and Child Obesity: The Causal Link

(2009) Emily Oken   OBSTETRICS AND GYNECOLOGY CLINICS OF NORTH AMERICA

Prenatal stress programming of offspring feeding behavior and energy balance begins early in pregnancy

(2009) Diana E. Pankevich et al.   PHYSIOLOGY & BEHAVIOR

Maternal Obesity Induced by Diet in Rats Permanently Influences Central Processes Regulating Food Intake in Offspring

(2009) Shona L. Kirk et al.   PLoS One

The Effect of Diet on the Human Gut Microbiome: A Metagenomic Analysis in Humanized Gnotobiotic Mice

(2009) P. J. Turnbaugh et al.   Science Translational Medicine

NRXN3 Is a Novel Locus for Waist Circumference: A Genome-Wide Association Study from the CHARGE Consortium

(2009) Nancy L. Heard-Costa et al.   PLoS Genetics

The Preventable Causes of Death in the United States: Comparative Risk Assessment of Dietary, Lifestyle, and Metabolic Risk Factors

(2009) Goodarz Danaei et al.   PLOS MEDICINE

Body energy homeostasis

(2008) Richard E. Keesey et al.   APPETITE

Prenatal psychosocial stress exposure is associated with insulin resistance in young adults

(2008) Sonja Entringer et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Insulin, leptin, and food reward: update 2008

(2008) Dianne P. Figlewicz et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Diet-Induced Obesity Is Linked to Marked but Reversible Alterations in the Mouse Distal Gut Microbiome

(2008) Peter J. Turnbaugh et al.   Cell Host & Microbe

Hypothalamic Neural Projections Are Permanently Disrupted in Diet-Induced Obese Rats

(2008) Sebastien G. Bouret et al.   Cell Metabolism

Selective versus Total Insulin Resistance: A Pathogenic Paradox

(2008) Michael S. Brown et al.   Cell Metabolism

Variants Near MC4R Are Associated With Obesity and Influence Obesity-Related Quantitative Traits in a Population of Middle-Aged People: Studies of 14,940 Danes

(2008) D. P. Zobel et al.   DIABETES

Lower Metabolic Rate in Individuals Heterozygous for Either a Frameshift or a Functional Missense MC4R Variant

(2008) J. Krakoff et al.   DIABETES

Ventromedial Hypothalamic Glucokinase Is an Important Mediator of the Counterregulatory Response to Insulin-Induced Hypoglycemia

(2008) B. E. Levin et al.   DIABETES

Genetic Variants of FTO Influence Adiposity, Insulin Sensitivity, Leptin Levels, and Resting Metabolic Rate in the Quebec Family Study

(2008) R. Do et al.   DIABETES

Influence of Maternal Obesity on Insulin Sensitivity and Secretion in Offspring

(2008) G. Mingrone et al.   DIABETES CARE

Effects of Leptin on Rat Ventromedial Hypothalamic Neurons

(2008) Boman G. Irani et al.   ENDOCRINOLOGY

Maternal and Postnatal Overnutrition Differentially Impact Appetite Regulators and Fuel Metabolism

(2008) Hui Chen et al.   ENDOCRINOLOGY

Prenatal exposure to maternal psychosocial stress and HPA axis regulation in young adults

(2008) Sonja Entringer et al.   HORMONES AND BEHAVIOR

Gestational diabetes: The forerunner for the development of maternal and childhood obesity and metabolic syndrome?

(2008) Betty R. Vohr et al.   Journal of Maternal-Fetal & Neonatal Medicine

Ghrelin Stimulates Milk Intake by Affecting Adult Type Feeding Behaviour in Postnatal Rats

(2008) H. Piao et al.   JOURNAL OF NEUROENDOCRINOLOGY

Maternal Care and Hippocampal Plasticity: Evidence for Experience-Dependent Structural Plasticity, Altered Synaptic Functioning, and Differential Responsiveness to Glucocorticoids and Stress

(2008) D. L. Champagne et al.   JOURNAL OF NEUROSCIENCE

Obesity and Functional Disability in Elderly Americans

(2008) Honglei Chen et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies

(2008) Andrew G Renehan et al.   LANCET

UCP2 mediates ghrelin’s action on NPY/AgRP neurons by lowering free radicals

(2008) Zane B. Andrews et al.   NATURE

Synaptic release of GABA by AgRP neurons is required for normal regulation of energy balance

(2008) Qingchun Tong et al.   NATURE NEUROSCIENCE

Age- and Gender-specific BMI in Terms of the Lowest Mortality in Japanese General Population

(2008) Tomoaki Matsuo et al.   Obesity

Persistent epigenetic differences associated with prenatal exposure to famine in humans

(2008) B. T. Heijmans et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Maternal nutrition, intrauterine programming and consequential risks in the offspring

(2008) Chittaranjan S. Yajnik et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Body Mass Index, Blood Pressure, and Mortality From Stroke

(2008) Maigeng Zhou et al.   STROKE

Neuroregulation of nonexercise activity thermogenesis and obesity resistance

(2007) Catherine M. Kotz et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Three weeks of early-onset exercise prolongs obesity resistance in DIO rats after exercise cessation

(2007) Christa M. Patterson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Maternal obesity at conception programs obesity in the offspring

(2007) Kartik Shankar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Cardiovascular Risk Factors and Venous Thromboembolism

(2007) Walter Ageno et al.   CIRCULATION

Maternal Perinatal Undernutrition Drastically Reduces Postnatal Leptin Surge and Affects the Development of Arcuate Nucleus Proopiomelanocortin Neurons in Neonatal Male Rat Pups

(2007) Fabien Delahaye et al.   ENDOCRINOLOGY

Diet-Induced Obesity in Female Mice Leads to Offspring Hyperphagia, Adiposity, Hypertension, and Insulin Resistance

(2007) Anne-Maj Samuelsson et al.   HYPERTENSION