Article
Nutrition & Dietetics
Hyo In Kim, Se Hyang Hong, Seo Yeon Lee, Jin Mo Ku, Min Jeong Kim, Seong-Gyu Ko
Summary: The study demonstrated the regulatory role of Gardenia jasminoides (GJ) on the intestinal microbiome in alleviating atopic dermatitis (AD) symptoms. GJ administration improved pathological changes induced by antibiotics and DNCB by restoring intestinal microbiome composition, suggesting its potential as a therapeutic agent for AD.
Review
Biochemistry & Molecular Biology
Ruxandra Florentina Ionescu, Robert Mihai Enache, Sanda Maria Cretoiu, Bogdan Severus Gaspar
Summary: This article summarizes the recent findings on the correlation between gestational diabetes mellitus (GDM) and dysbiosis, as well as the prevention and treatment methods. The most common changes in the microbiome of GDM patients are an increase in Firmicutes phylum or a decrease in Bacteroidetes and Actinobacteria phyla. Gut dysbiosis persists postpartum and affects the development of newborns. Probiotic supplementation and regular physical activity have strong evidence in controlling blood glucose levels.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biotechnology & Applied Microbiology
Gang Zhao, Mingpu Qi, Qiankun Wang, Changmin Hu, Xiang Li, Yingyu Chen, Jingyuan Yang, Huiliang Yu, Huanchun Chen, Aizhen Guo
Summary: This study aimed to analyze the factors affecting the gut microbiome of snub-nosed monkeys, including raising patterns, age, sex, and diarrheal status, and provide reference for protection strategies. The results showed that raising pattern was the predominant factor influencing the microbiome structure and proportionality, with wild monkeys having higher bacterial diversity and captive monkeys having higher diversity of antibiotic resistant genes.
Review
Immunology
Ziqi Yu, Xiang Shen, Aiyao Wang, Chong Hu, Jianyong Chen
Summary: Tuberculosis (TB) is a significant global public health concern, with pulmonary TB being the most common form of the disease. However, intestinal TB (ITB), which is mostly secondary to pulmonary TB, is also a significant issue. Recent studies have investigated the potential role of the gut microbiome in TB development. This review summarizes the findings of studies investigating the gut microbiome in both pulmonary TB and ITB patients compared with healthy controls, highlighting the crucial role of the gut microbiome in TB, particularly in ITB development.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2023)
Article
Medicine, General & Internal
Emilia Sawicka-Smiarowska, Kinga Bondarczuk, Witold Bauer, Magdalena Niemira, Anna Szalkowska, Justyna Raczkowska, Miroslaw Kwasniewski, Ewa Tarasiuk, Marlena Dubatowka, Magda Lapinska, Malgorzata Szpakowicz, Zofia Stachurska, Anna Szpakowicz, Pawel Sowa, Andrzej Raczkowski, Marcin Kondraciuk, Magdalena Gierej, Joanna Motyka, Jacek Jamiolkowski, Mateusz Bondarczuk, Malgorzata Chlabicz, Jolanta Bucko, Marcin Kozuch, Slawomir Dobrzycki, Jerzy Bychowski, Wlodzimierz Jerzy Musial, Adrian Godlewski, Michal Ciborowski, Attila Gyenesei, Adam Kretowski, Karol Adam Kaminski
Summary: Despite knowledge of classical coronary artery disease (CAD) risk factors, the morbidity and mortality associated with this disease remain high. New factors that may affect the development of CAD, such as the gut microbiome, are extensively investigated. CAD is associated with altered gut microbiome composition and function, including changes in Firmicutes/Bacteroidetes ratio and alpha-beta biodiversity.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Ophthalmology
Rehana Khan, Abhishek Sharma, Raghul Ravikumar, Avani Parekh, Ramyaa Srinivasan, Ronnie Jacob George, Rajiv Raman
Summary: The B/F ratio in diabetic patients may be a potential biomarker for the development of sight-threatening diabetic retinopathy, but no significant differences in gut microbial abundance for any specific phylum were found between the control and diseased population.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2021)
Article
Agriculture, Dairy & Animal Science
Stella Agradi, Paola Cremonesi, Laura Menchetti, Claudia Balzaretti, Marco Severgnini, Federica Riva, Bianca Castiglioni, Susanna Draghi, Alessia Di Giancamillo, Marta Castrica, Daniele Vigo, Silvia Clotilde Modina, Valentina Serra, Alda Quattrone, Elisa Angelucci, Grazia Pastorelli, Giulio Curone, Gabriele Brecchia
Summary: BC is a nutraceutical that can modulate intestinal microbiota. This study investigates the effects of BC diet supplementation on luminal and mucosa-associated microbiota in the jejunum, caecum, and colon of rabbits. Significant differences were found in the microbial composition of the three groups, especially in the caecum and colon of the 2.5% BC group. A functional prediction has revealed several altered pathways in BC groups, with particular reference to amino acids and lactose metabolism. Findings suggest that BC supplementation could positively affect the intestinal microbiota.
Review
Biochemistry & Molecular Biology
Giulia Gibiino, Martina De Siena, Monica Sbrancia, Cecilia Binda, Vittorio Sambri, Antonio Gasbarrini, Carlo Fabbri
Summary: Diet plays a crucial role in influencing our intestinal microbiota and ecosystem balance, but a clearly defined dietary regime to ensure its health is still lacking. The Mediterranean diet may potentially have significant benefits for our health through direct interaction with our microbiota.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Nutrition & Dietetics
Rawan Almutairi, Abigail Raffner Basson, Pamela Wearsh, Fabio Cominelli, Alexander Rodriguez-Palacios
Summary: This study conducted a systematic review of clinical trials using MDX as a placebo and evaluated its effects on human physiology and gut microbiota. The results showed that MDX often induces effects on human physiology and gut microbiota, questioning its validity as a placebo-control in clinical trials.
EUROPEAN JOURNAL OF NUTRITION
(2022)
Article
Nutrition & Dietetics
Martha Alejandra Chavoya-Guardado, Edgar Manuel Vasquez-Garibay, Sandra Luz Ruiz-Quezada, Maria Ines Ramirez-Cordero, Alfredo Larrosa-Haro, Jorge Castro-Albarran
Summary: This study found that the adiposity of women before pregnancy and during lactation is associated with the abundance of Bacteroidetes and Actinobacteria in human milk. This finding reveals a relationship between the microbiota of human milk and the mother's obesity status.
Article
Biochemical Research Methods
Zoltan Toth, Attila Bezzegh, Akos Torde, Barna Vasarhelyi, Bela Gyarmati
Summary: The study investigates the short-term alteration of gut microbiome after antibiotic therapy in patients undergoing prostate biopsy. The findings show changes in the composition of gut microbiome, but the long-term effects or implications on diseases such as prostate pathology are still unknown.
MOLECULAR AND CELLULAR PROBES
(2022)
Article
Infectious Diseases
Qiulin Xiao, Bo Chen, Zhenya Zhu, Ting Yang, Enfu Tao, Chenmin Hu, Wei Zheng, Weihong Tang, Xiaoli Shu, Mizu Jiang
Summary: The objective of this study was to investigate the association between fecal microbiota and acute diarrhea in children, specifically with rotavirus infection. It was found that children with acute diarrhea exhibited dysbiosis in their gut microbiota, with lower microbial diversity and richness compared to the control group. The composition of the microbiota also differed between the acute diarrhea group and the control group.
INFECTION AND DRUG RESISTANCE
(2023)
Article
Microbiology
Akarsh Mathrani, Louise W. Lu, Ivana R. Sequeira-Bisson, Marta P. Silvestre, Michael Hoggard, Daniel Barnett, Mikael Fogelholm, Anne Raben, Sally D. Poppitt, Michael W. Taylor
Summary: Obesity-related metabolic diseases, such as type 2 diabetes, are prevalent worldwide. Ethnicity plays a role in susceptibility to these diseases, and the gut microbiota may also have an influence. This study compared the fecal microbiota of European-ancestry and Chinese-ancestry cohorts with overweight and prediabetes in New Zealand, revealing significant microbiota differences between the ethnicities.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Nutrition & Dietetics
Hye Rim Kim, Eunsol Seo, Seyeon Oh, MinYeong Seo, Kyunghee Byun, Byung-Yong Kim
Summary: This study demonstrates that multi-strain probiotic treatment can alleviate obesity induced by high-carbohydrate diet, modulating the expression of genes related to fat composition, fat metabolism, and thermogenesis. It also improves the levels of obesity-related hormones and reverses the Firmicutes/Bacteroidetes ratio in the gut microbiota.
Article
Gastroenterology & Hepatology
Min-Woo Chung, Moon-Ju Kim, Eun Jeong Won, Yu Jeong Lee, Yong-Woon Yun, Sung Bum Cho, Young-Eun Joo, Jun-Eul Hwang, Woo Kyun Bae, Ik-Joo Chung, Myung Geun Shin, Jong Hee Shin
Summary: This study collected fecal samples from advanced HCC patients treated with nivolumab and found that responders had higher gut bacterial diversity compared to non-responders. The study also identified specific bacterial taxa associated with therapeutic response in HCC patients. Additionally, certain bacterial ratios and species were proposed as predictive markers for response to nivolumab in HCC treatment.
WORLD JOURNAL OF GASTROENTEROLOGY
(2021)
Article
Environmental Sciences
Lucas Rocha-Melogno, Katherine Crank, Michael H. Bergin, Gregory C. Gray, Kyle Bibby, Marc A. Deshusses
Summary: An increasing body of literature suggests that aerosol inhalation plays a primary role in COVID-19 transmission, particularly in indoor settings. In response to this, the authors developed a model and web application to assess and mitigate the risk of aerosol transmission. Their findings showed that the risk of transmission significantly increased when masks were not worn and the room was poorly ventilated, but it could be reduced with proper ventilation and relative humidity.
ENVIRONMENTAL TECHNOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Sean Cavany, Aaron Bivins, Zhenyu Wu, Devin North, Kyle Bibby, T. Alex Perkins
Summary: A study suggests that RNA shedding of SARS-CoV-2 into wastewater peaks around 6 days after infection, and wastewater surveillance has limited utility in predicting transmission trends. It may be most useful as an early warning in areas with low transmission or delayed/limited clinical testing.
EPIDEMIOLOGY AND INFECTION
(2022)
Article
Polymer Science
Madeline G. Jensen, Patrick T. O'Shaughnessy, Marlee Shaffer, Sooyoun Yu, Yun Young Choi, Megan Christiansen, Charles O. Stanier, Michael Hartley, Joey Huddle, Jed Johnson, Kyle Bibby, Nosang V. Myung, David M. Cwiertny
Summary: During the global spread of COVID-19, the high demand and limited availability of melt-blown filtration material led to a manufacturing backlog of N95 Filtering Facepiece Respirators (FFRs). An alternative filter material, consisting of electrospun polystyrene (PS) microfibers, showed favorable performance in terms of filtration efficiency and antibacterial activity, potentially making it a suitable option for use in N95 FFRs.
JOURNAL OF APPLIED POLYMER SCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Pedro F. P. Brandao-Dias, Daniel M. C. Hallack, Elise D. D. Snyder, Jennifer L. L. Tank, Diogo Bolster, Sabrina Volponi, Arial J. J. Shogren, Gary A. A. Lamberti, Kyle Bibby, Scott P. P. Egan
Summary: Environmental DNA (eDNA) analysis is a powerful tool for detecting target organisms remotely. This study explores the possibility of obtaining longitudinal dynamics information on targets by separating different size components of eDNA within a sample. The results show that medium-sized particles decay more slowly and increase in proportion over time. Different sizes of eDNA particles do not decay independently, but a parsimonious mathematical model best explains the data. A framework for discerning target distance and abundance with eDNA data is proposed.
MOLECULAR ECOLOGY RESOURCES
(2023)
Review
Environmental Sciences
Ananda Tiwari, Sangeet Adhikari, Devrim Kaya, Md. Aminul Islam, Bikash Malla, Samendra P. Sherchan, Ahmad I. Al-Mustapha, Manish Kumar, Srijan Aggarwal, Prosun Bhattacharya, Kyle Bibby, Rolf U. Halden, Aaron Bivins, Eiji Haramoto, Sami Oikarinen, Annamari Heikinheimo, Tarja Pitkaenen
Summary: Monkeypox disease, caused by the monkeypox virus, has become a global concern. Wastewater-based surveillance can be a useful tool for early detection of the virus, but there are challenges to overcome.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Chemistry, Multidisciplinary
Brooke Stemple, Djuna Gulliver, Kara Tinker, Preom Sarkar, Josh Miller, Kyle Bibby
Summary: This study characterizes the impact of long-term storage of supercritical CO2 in depleted oil reservoirs on subsurface biogeochemistry, focusing on the geochemical and microbial composition of produced water from CO2 enhanced oil recovery (CO2 EOR) wells in the Niagaran Pinnacle Reef. The results indicate that high salinity and supercritical CO2 conditions select for stress-tolerant microbial communities adapted to these environments.
ACS EARTH AND SPACE CHEMISTRY
(2022)
Article
Engineering, Environmental
Olivia Ginn, Jennifer L. Tank, Andrei Badilla-Aguilar, Elise Snyder, Pedro F. P. Brandao-Dias, Emma Thrift, Diogo Bolster, Kyle Bibby
Summary: Environmental factors play a critical role in understanding the fate and transport of antibiotic resistance in impacted streams. This study examines the impact of stream characteristics and particle size association on the removal of antimicrobial resistance genes over time. The findings suggest that both substrate and particle size influence the behavior and removal rates of antibiotic resistance genes in surface waters.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Environmental Sciences
William Chen, Kyle Bibby
Summary: Wastewater-based epidemiology (WBE) is a community-level monitoring technique used to track diseases, but its feasibility for monitoring vector-borne pathogens like Zika virus is uncertain. Monte Carlo simulation was used to generate distributions for total Zika RNA shedding and the process limit of detection (PLOD), and the probability of detecting Zika RNA in wastewater was calculated. Results suggest that successful Zika WBE application is unlikely in the United States but likely in Zika-endemic countries with decreased wastewater treatment plant (WWTP) per capita flows. However, the great discrepancy between true and reported clinical cases suggests that Zika WBE may be feasible even in the absence of outbreaks in endemic countries.
Article
Engineering, Environmental
Pedro F. P. Brandao-Dias, Jennifer L. Tank, Elise D. Snyder, Ursula H. Mahl, Brett Peters, Diogo Bolster, Arial J. Shogren, Gary A. Lamberti, Kyle Bibby, Scott P. Egan
Summary: eDNA in aquatic systems is a complex mixture that includes dissolved DNA, intracellular DNA, and particle-adsorbed DNA. Understanding the composition and interactions of eDNA is crucial for determining the abundance and location of target organisms. This study found that eDNA rapidly adsorbs to other materials in the water column, affecting its concentration and particle size distribution. Only particulate organic matter affected the removal rate of eDNA. The removal of larger eDNA components was influenced by physical processes, while the removal of smaller eDNA components was driven by biological degradation.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Engineering, Environmental
William Chen, Kyle Bibby
Summary: This paper discusses the importance of wastewater-based surveillance in understanding the occurrence and spread of infectious diseases and proposes a framework to assess the suitability of novel diseases for wastewater monitoring. The paper also explores five primary factors that influence the detection probability in wastewater-based surveillance and emphasizes the need for further research on these factors.
Article
Engineering, Environmental
Emily Clements, Christopher Irwin, Jacob Koestner, Alexandros Taflanidis, Kyle Bibby, Robert Nerenberg
Summary: This research proposes using statistical tools to assess water age distributions and highlights that average water age is not a reliable indicator of water quality. The study demonstrates that changes in occupancy have a greater impact on water age than changes in average water demand.
ENVIRONMENTAL SCIENCE-WATER RESEARCH & TECHNOLOGY
(2023)
Article
Environmental Sciences
Rasha Maal-Bared, Charles Gerba, Kyle Bibby, Naoko Munakata, Anna S. Mehrotra, Kari Fitzmorris Brisolara, Charles Haas, Lee Gary, Bina Nayak, Jay Swift, Samendra Sherchan, Leonard Casson, Lola Olabode, Albert Rubin, Robert Reimers, Mark Sobsey
Summary: Recent safety concerns in the water sector during the COVID-19 pandemic have emphasized the importance of industry-focused reviews on emerging pathogens to support evidence-based decision-making. This study provides a summary of the available evidence on monkeypox virus (MPXV) and related orthopoxviruses and offers sector-wide recommendations. Based on the current information, there is no evidence to suggest that infectious MPXV is present in wastewater or biosolids, and the outbreak is unlikely to pose a transmission risk from these sources.
Article
Engineering, Environmental
Justin Greaves, Devin North, Kyle Bibby
Summary: The molecular viral fecal pollution indicators have emerged as leading candidates for water quality monitoring. This study investigates the associations of six molecular fecal pollution targets with particles in wastewater and finds that the targets have the highest concentrations on suspended particles, suggesting that particle association dictates their transport in environmental waters.
ENVIRONMENTAL SCIENCE-WATER RESEARCH & TECHNOLOGY
(2022)
Article
Environmental Sciences
Warish Ahmed, Wendy J. M. Smith, Suzanne Metcalfe, Greg Jackson, Phil M. Choi, Mary Morrison, Daniel Field, Pradip Gyawali, Aaron Bivins, Kyle Bibby, Stuart L. Simpson
Summary: This study compared the performance of RT-qPCR and RT-dPCR platforms in detecting SARS-CoV-2 RNA in low-prevalence locations in Queensland, Australia. The results showed that RT-dPCR had a lower limit of detection and a higher detection rate than RT-qPCR in both eluate and pellet samples.
Correction
Public, Environmental & Occupational Health
Sean Cavany, Aaron Bivins, Zhenyu Wu, Devin North, Kyle Bibby, T. Alex Perkins
EPIDEMIOLOGY AND INFECTION
(2022)