标题
Non-enzymatic molecular damage as a prototypic driver of aging
作者
关键词
-
出版物
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 292, Issue 15, Pages 6029-6038
出版商
American Society for Biochemistry & Molecular Biology (ASBMB)
发表日期
2017-03-07
DOI
10.1074/jbc.r116.751164
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Aging: progressive decline in fitness due to the rising deleteriome adjusted by genetic, environmental, and stochastic processes
- (2016) Vadim N. Gladyshev AGING CELL
- 'Nothing of chemistry disappears in biology: the Top 30 damage-prone endogenous metabolites
- (2016) C. Lerma-Ortiz et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Methylglyoxal-induced dicarbonyl stress in aging and disease: first steps towards glyoxalase 1-based treatments
- (2016) N. Rabbani et al. CLINICAL SCIENCE
- Role of chaperone-mediated autophagy in metabolism
- (2016) Inmaculada Tasset et al. FEBS Journal
- Carnosine and the processes of ageing
- (2016) Alan R. Hipkiss et al. MATURITAS
- Neuromelanin marks the spot: identifying a locus coeruleus biomarker of cognitive reserve in healthy aging
- (2016) David V. Clewett et al. NEUROBIOLOGY OF AGING
- Paradoxical Roles of Antioxidant Enzymes: Basic Mechanisms and Health Implications
- (2016) Xin Gen Lei et al. PHYSIOLOGICAL REVIEWS
- Reactome from a WikiPathways Perspective
- (2016) Anwesha Bohler et al. PLoS Computational Biology
- A Genome-Scale Database and Reconstruction of Caenorhabditis elegans Metabolism
- (2016) Juliane Gebauer et al. Cell Systems
- Site-Specific Reactivity of Nonenzymatic Lysine Acetylation
- (2015) Josue Baeza et al. ACS Chemical Biology
- Evidence that mutation accumulation does not cause aging inSaccharomyces cerevisiae
- (2015) Alaattin Kaya et al. AGING CELL
- The effects of age and dietary restriction on the tissue-specific metabolome ofDrosophila
- (2015) Matthew J. Laye et al. AGING CELL
- A directed-overflow and damage-controlN-glycosidase in riboflavin biosynthesis
- (2015) Océane Frelin et al. BIOCHEMICAL JOURNAL
- Genomic and experimental evidence for multiple metabolic functions in the RidA/YjgF/YER057c/UK114 (Rid) protein family
- (2015) Thomas D Niehaus et al. BMC GENOMICS
- A Call for Systematic Research on Solute Carriers
- (2015) Adrián César-Razquin et al. CELL
- Organization of the Mammalian Metabolome according to Organ Function, Lineage Specialization, and Longevity
- (2015) Siming Ma et al. Cell Metabolism
- The ɛ-Amino Group of Protein Lysine Residues Is Highly Susceptible to Nonenzymatic Acylation by Several Physiological Acyl-CoA Thioesters
- (2015) Zeljko Simic et al. CHEMBIOCHEM
- Bacterial protein acetylation: new discoveries unanswered questions
- (2015) Alan J. Wolfe CURRENT GENETICS
- Analysis of acetylation stoichiometry suggests that SIRT3 repairs nonenzymatic acetylation lesions
- (2015) B. T. Weinert et al. EMBO JOURNAL
- Metabolome and proteome changes with aging in Caenorhabditis elegans
- (2015) Neil Copes et al. EXPERIMENTAL GERONTOLOGY
- Norepinephrine and its metabolites are involved in the synthesis of neuromelanin derived from thelocus coeruleus
- (2015) Kazumasa Wakamatsu et al. JOURNAL OF NEUROCHEMISTRY
- Fusion leads to effective segregation of damage during cell division: An analytical treatment
- (2015) Steven J. Lade et al. JOURNAL OF THEORETICAL BIOLOGY
- Protein modification and maintenance systems as biomarkers of ageing
- (2015) Valerie Vanhooren et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Proteostasis and aging
- (2015) Susmita Kaushik et al. NATURE MEDICINE
- DNA–protein crosslink repair
- (2015) Julian Stingele et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of pathway/genome databases
- (2015) Ron Caspi et al. NUCLEIC ACIDS RESEARCH
- Nonenzymatic Reactions above Phospholipid Surfaces of Biological Membranes: Reactivity of Phospholipids and Their Oxidation Derivatives
- (2015) Christian Solís-Calero et al. Oxidative Medicine and Cellular Longevity
- Constant mortality and fertility over age inHydra
- (2015) Ralf Schaible et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- SOD1 aggregation in ALS mice shows simplistic test tube behavior
- (2015) Lisa Lang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Protein carbamylation is a hallmark of aging
- (2015) Laëtitia Gorisse et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Are dopamine derivatives implicated in the pathogenesis of Parkinson's disease?
- (2014) Marco Bisaglia et al. AGEING RESEARCH REVIEWS
- Naturally-occurring tetrahydro-β-carboline alkaloids derived from tryptophan are oxidized to bioactive β-carboline alkaloids by heme peroxidases
- (2014) Tomás Herraiz et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Parkinsonism-associated Protein DJ-1/Park7 Is a Major Protein Deglycase That Repairs Methylglyoxal- and Glyoxal-glycated Cysteine, Arginine, and Lysine Residues
- (2014) Gilbert Richarme et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Metabolomics of Human Brain Aging and Age-Related Neurodegenerative Diseases
- (2014) Mariona Jové et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Nonenzymatic Protein Acylation as a Carbon Stress Regulated by Sirtuin Deacylases
- (2014) Gregory R. Wagner et al. MOLECULAR CELL
- Plants Utilize a Highly Conserved System for Repair of NADH and NADPH Hydrates
- (2014) T. D. Niehaus et al. PLANT PHYSIOLOGY
- Reactive Carbonyl SpeciesIn Vivo: Generation and Dual Biological Effects
- (2014) Halyna M. Semchyshyn TheScientificWorldJOURNAL
- A review of the volatiles from the healthy human body
- (2014) B de Lacy Costello et al. Journal of Breath Research
- The role of protein clearance mechanisms in organismal ageing and age-related diseases
- (2014) David Vilchez et al. Nature Communications
- Age- and diet-associated metabolome remodeling characterizes the aging process driven by damage accumulation
- (2014) Andrei S Avanesov et al. eLife
- The Free Radical Theory of Aging Is Dead. Long Live the Damage Theory!
- (2013) Vadim N. Gladyshev ANTIOXIDANTS & REDOX SIGNALING
- Catecholamine metabolism drives generation of mitochondrial DNA deletions in dopaminergic neurons
- (2013) Johannes F.G. Neuhaus et al. BRAIN
- Identification of Long-Lived Proteins Reveals Exceptional Stability of Essential Cellular Structures
- (2013) Brandon H. Toyama et al. CELL
- Chemistry of the Retinoid (Visual) Cycle
- (2013) Philip D. Kiser et al. CHEMICAL REVIEWS
- Advanced glycoxidation and lipoxidation end products (AGEs and ALEs): an overview of their mechanisms of formation
- (2013) G. Vistoli et al. FREE RADICAL RESEARCH
- Metabolite damage and its repair or pre-emption
- (2013) Carole L Linster et al. Nature Chemical Biology
- Neuromelanin of the Human Substantia Nigra: An Update
- (2013) Fabio A. Zucca et al. NEUROTOXICITY RESEARCH
- A method for accounting for maintenance costs in flux balance analysis improves the prediction of plant cell metabolic phenotypes under stress conditions
- (2013) C. Y. Maurice Cheung et al. PLANT JOURNAL
- DNA Repair Pathway Choice Is Influenced by the Health of Drosophila melanogaster
- (2012) A. D. Wang et al. GENETICS
- Frontiers in metabolic reconstruction and modeling of plant genomes
- (2012) S. M. D. Seaver et al. JOURNAL OF EXPERIMENTAL BOTANY
- Protein homeostasis: live long, won't prosper
- (2012) Brandon H. Toyama et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The Pictet-Spengler Reaction in Nature and in Organic Chemistry
- (2011) Joachim Stöckigt et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- A multi-tissue type genome-scale metabolic network for analysis of whole-body systems physiology
- (2011) Aarash Bordbar et al. BMC Systems Biology
- Microautophagy: lesser-known self-eating
- (2011) Wen-wen Li et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Somatic mutations in aging, cancer and neurodegeneration
- (2011) Scott R. Kennedy et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Enzymatic repair of Amadori products
- (2010) Emile Van Schaftingen et al. AMINO ACIDS
- When a theory of aging ages badly
- (2009) Jérôme Lapointe et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- How could the Gompertz–Makeham law evolve
- (2009) A. Golubev JOURNAL OF THEORETICAL BIOLOGY
- ABC Transporters in Saccharomyces cerevisiae and Their Interactors: New Technology Advances the Biology of the ABCC (MRP) Subfamily
- (2009) C. M. Paumi et al. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
- Membrane phospholipids, lipoxidative damage and molecular integrity: A causal role in aging and longevity
- (2008) Reinald Pamplona BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Relationships among carbohydrate intermediate metabolites and DNA damage and repair in yeast from a systems biology perspective
- (2008) Fernanda Barea et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- The tandem of free radicals and methylglyoxal
- (2007) Miklós Péter Kalapos CHEMICO-BIOLOGICAL INTERACTIONS
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