The effects of age and dietary restriction on the tissue-specific metabolome ofDrosophila

dSir2 mediates the increased spontaneous physical activity in flies on calorie restriction

(2016) Vijay Parashar et al.   Aging-US

Dietary switch reveals fast coordinated gene expression changes in Drosophila melanogaster

(2016) Rachel Whitaker et al.   Aging-US

Effects of age, sex, and genotype on high-sensitivity metabolomic profiles in the fruit fly,Drosophila melanogaster

(2014) Jessica M. Hoffman et al.   AGING CELL

Geroscience: Linking Aging to Chronic Disease

(2014) Brian K. Kennedy et al.   CELL

Nucleocytosolic Depletion of the Energy Metabolite Acetyl-Coenzyme A Stimulates Autophagy and Prolongs Lifespan

(2014) Tobias Eisenberg et al.   Cell Metabolism

Cold adaptation shapes the robustness of metabolic networks inDrosophila melanogaster

(2014) Caroline M. Williams et al.   EVOLUTION

Age- and diet-associated metabolome remodeling characterizes the aging process driven by damage accumulation

(2014) Andrei S Avanesov et al.   eLife

Metformin Retards Aging in C. elegans by Altering Microbial Folate and Methionine Metabolism

(2013) Filipe Cabreiro et al.   CELL

Autophagy and leucine promote chronological longevity and respiration proficiency during calorie restriction in yeast

(2013) John P. Aris et al.   EXPERIMENTAL GERONTOLOGY

Metabolomic markers reveal novel pathways of ageing and early development in human populations

(2013) Cristina Menni et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Metabolic Phenotype Modulation by Caloric Restriction in a Lifelong Dog Study

(2013) Selena E. Richards et al.   JOURNAL OF PROTEOME RESEARCH

Acetyl-l-carnitine rescues scopolamine-induced memory deficits by restoring insulin-like growth factor II via decreasing p53 oxidation

(2013) Xiang Wang et al.   NEUROPHARMACOLOGY

Mapping an Atlas of Tissue-Specific Drosophila melanogaster Metabolomes by High Resolution Mass Spectrometry

(2013) Venkateswara R. Chintapalli et al.   PLoS One

Dissection of Regulatory Networks that Are Altered in Disease via Differential Co-expression

(2013) David Amar et al.   PLoS Computational Biology

Predicting Network Activity from High Throughput Metabolomics

(2013) Shuzhao Li et al.   PLoS Computational Biology

Chronic caloric restriction partially protects against age-related alteration in serum metabolome

(2012) Jennifer M. De Guzman et al.   AGE

A metabolic signature predicts biological age in mice

(2012) Antonia Tomás-Loba et al.   AGING CELL

Nutritional Metabolomics: Progress in Addressing Complexity in Diet and Health

(2012) Dean P. Jones et al.   Annual Review of Nutrition

The sva package for removing batch effects and other unwanted variation in high-throughput experiments

(2012) Jeffrey T. Leek et al.   BIOINFORMATICS

Intramyocellular Fatty-Acid Metabolism Plays a Critical Role in Mediating Responses to Dietary Restriction in Drosophila melanogaster

(2012) Subhash D. Katewa et al.   Cell Metabolism

Short-Term Calorie Restriction Enhances Skeletal Muscle Stem Cell Function

(2012) Massimiliano Cerletti et al.   Cell Stem Cell

Ageing as a Risk Factor for Disease

(2012) Teresa Niccoli et al.   CURRENT BIOLOGY

The Metabolic Profile of Long-Lived Drosophila melanogaster

(2012) Pernille Sarup et al.   PLoS One

Lipoproteins in Drosophila melanogaster—Assembly, Function, and Influence on Tissue Lipid Composition

(2012) Wilhelm Palm et al.   PLoS Genetics

Metabolomic correlation-network modules in Arabidopsis based on a graph-clustering approach

(2011) Atsushi Fukushima et al.   BMC Systems Biology

Applications of mass spectrometry to metabolomics and metabonomics: Detection of biomarkers of aging and of age-related diseases

(2011) Robert J. Mishur et al.   MASS SPECTROMETRY REVIEWS

Weighted Correlation Network Analysis (WGCNA) Applied to the Tomato Fruit Metabolome

(2011) Matthew V. DiLeo et al.   PLoS One

Nutritional influences on epigenetics and age-related disease

(2011) Lara K. Park et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

Age-associated development of inflammation in Wistar rats: Effects of caloric restriction

(2011) Daniel Horrillo et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

DiffCoEx: a simple and sensitive method to find differentially coexpressed gene modules

(2010) Bruno M Tesson et al.   BMC BIOINFORMATICS

A metabolic signature of long life in Caenorhabditis elegans

(2010) Silke Fuchs et al.   BMC BIOLOGY

With TOR, Less Is More: A Key Role for the Conserved Nutrient-Sensing TOR Pathway in Aging

(2010) Pankaj Kapahi et al.   Cell Metabolism

A Network Perspective on Metabolism and Aging

(2010) Q. A. Soltow et al.   INTEGRATIVE AND COMPARATIVE BIOLOGY

Effect of Caloric Restriction with and without Exercise on Metabolic Intermediates in Nonobese Men and Women

(2010) Leanne M. Redman et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Extending Healthy Life Span--From Yeast to Humans

(2010) L. Fontana et al.   SCIENCE

The Complex Genetic Architecture of the Metabolome

(2010) Eva K. F. Chan et al.   PLoS Genetics

4E-BP Extends Lifespan upon Dietary Restriction by Enhancing Mitochondrial Activity in Drosophila

(2009) Brian M. Zid et al.   CELL

Folic Acid, Neurodegenerative and Neuropsychiatric Disease

(2009) Golo Kronenberg et al.   CURRENT MOLECULAR MEDICINE

Metabolic shifts due to long-term caloric restriction revealed in nonhuman primates

(2009) Serge Rezzi et al.   EXPERIMENTAL GERONTOLOGY

Age-Associated Decrease of High-Density Lipoprotein-Mediated Reverse Cholesterol Transport Activity

(2009) Hicham Berrougui et al.   REJUVENATION RESEARCH

Aging Mice Show a Decreasing Correlation of Gene Expression within Genetic Modules

(2009) Lucinda K. Southworth et al.   PLoS Genetics

Aging and Survival: The Genetics of Life Span Extension by Dietary Restriction

(2008) William Mair et al.   Annual Review of Biochemistry

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS