Mechanisms and treatments for severe, steroid-resistant allergic airway disease and asthma
出版年份 2017 全文链接
标题
Mechanisms and treatments for severe, steroid-resistant allergic airway disease and asthma
作者
关键词
-
出版物
IMMUNOLOGICAL REVIEWS
Volume 278, Issue 1, Pages 41-62
出版商
Wiley
发表日期
2017-06-29
DOI
10.1111/imr.12543
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Features of the bronchial bacterial microbiome associated with atopy, asthma, and responsiveness to inhaled corticosteroid treatment
- (2017) Juliana Durack et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- MicroRNA-21 drives severe, steroid-insensitive experimental asthma by amplifying phosphoinositide 3-kinase–mediated suppression of histone deacetylase 2
- (2017) Richard Y. Kim et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- MicroRNA-155 is a critical regulator of type 2 innate lymphoid cells and IL-33 signaling in experimental models of allergic airway inflammation
- (2017) Kristina Johansson et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Inflammasomes in the lung
- (2017) James W. Pinkerton et al. MOLECULAR IMMUNOLOGY
- TRAIL deficiency and PP2A activation with salmeterol ameliorates egg allergen-driven eosinophilic esophagitis
- (2016) Leon A. Sokulsky et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Programmed Death Ligand 1 Promotes Early-LifeChlamydiaRespiratory Infection–Induced Severe Allergic Airway Disease
- (2016) Malcolm R. Starkey et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Characterization of asthma endotypes: implications for therapy
- (2016) Jeffrey R. Stokes et al. ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY
- Airway Surfactant Protein D Deficiency in Adults With Severe Asthma
- (2016) Rose-Marie A. Mackay et al. CHEST
- Effect of GST variants on lung function following diesel exhaust and allergen co-exposure in a controlled human crossover study
- (2016) Xin Zhang et al. FREE RADICAL BIOLOGY AND MEDICINE
- Inhaled Fine Particles Induce Alveolar Macrophage Death and Interleukin-1α Release to Promote Inducible Bronchus-Associated Lymphoid Tissue Formation
- (2016) Etsushi Kuroda et al. IMMUNITY
- TLR2 ligation induces corticosteroid insensitivity in A549 lung epithelial cells: Anti-inflammatory impact of PP2A activators
- (2016) Md. Mostafizur Rahman et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Group 2 innate lymphoid cells mediate ozone-induced airway inflammation and hyperresponsiveness in mice
- (2016) Qi Yang et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Increased numbers of activated group 2 innate lymphoid cells in the airways of patients with severe asthma and persistent airway eosinophilia
- (2016) Steven G. Smith et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Controlled diesel exhaust and allergen coexposure modulates microRNA and gene expression in humans: Effects on inflammatory lung markers
- (2016) Christopher F. Rider et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Holding the Inflammatory System in Check: TLRs and Their Targeted Therapy in Asthma
- (2016) Zhiyong Dong et al. MEDIATORS OF INFLAMMATION
- Emerging pathogenic links between microbiota and the gut–lung axis
- (2016) Kurtis F. Budden et al. NATURE REVIEWS MICROBIOLOGY
- The Impact of Respiratory Syncytial Virus Disease Prevention on Pediatric Asthma
- (2016) Mauricio T. Caballero et al. PEDIATRIC INFECTIOUS DISEASE JOURNAL
- Chronic Chlamydia pneumoniae lung infection: a neglected explanation for macrolide effects in wheezing and asthma?
- (2016) David L Hahn et al. Lancet Respiratory Medicine
- MicroRNAs as therapeutics for future drug delivery systems in treatment of lung diseases
- (2016) Kamal Dua et al. Drug Delivery and Translational Research
- TLR2, TLR4 AND MyD88 Mediate Allergic Airway Disease (AAD) and Streptococcus pneumoniae-Induced Suppression of AAD
- (2016) Alison N. Thorburn et al. PLoS One
- Targeting PI3K-p110α Suppresses Influenza Virus Infection in Chronic Obstructive Pulmonary Disease
- (2015) Alan Chen-Yu Hsu et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Cyclooxygenase-2 and MicroRNA-155 Expression Are Elevated in Asthmatic Airway Smooth Muscle Cells
- (2015) Brian S. Comer et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- The Nucleotide-Binding Domain, Leucine-Rich Repeat Protein 3 Inflammasome/IL-1 Receptor I Axis Mediates Innate, but Not Adaptive, Immune Responses after Exposure to Particulate Matter under 10 μm
- (2015) Jeremy A. Hirota et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Airway dysbiosis:Haemophilus influenzaeandTropherymain poorly controlled asthma
- (2015) Jodie L. Simpson et al. EUROPEAN RESPIRATORY JOURNAL
- Estrogen and progesterone decrease let-7f microRNA expression and increase IL-23/IL-23 receptor signaling and IL-17A production in patients with severe asthma
- (2015) Dawn C. Newcomb et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- The airway microbiome in patients with severe asthma: Associations with disease features and severity
- (2015) Yvonne J. Huang et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- CD8 T cells and dendritic cells: key players in the attenuated maternal immune response to influenza infection
- (2015) Rebecca L. Vanders et al. JOURNAL OF REPRODUCTIVE IMMUNOLOGY
- A pathogenic role for tumor necrosis factor-related apoptosis-inducing ligand in chronic obstructive pulmonary disease
- (2015) T J Haw et al. Mucosal Immunology
- Mucosal production of uric acid by airway epithelial cells contributes to particulate matter-induced allergic sensitization
- (2015) M J Gold et al. Mucosal Immunology
- Heterogeneity in mechanisms influencing glucocorticoid sensitivity: The need for a systems biology approach to treatment of glucocorticoid-resistant inflammation
- (2015) Christine R. Keenan et al. PHARMACOLOGY & THERAPEUTICS
- Macrolide therapy suppresses key features of experimental steroid-sensitive and steroid-insensitive asthma
- (2015) Ama-Tawiah Essilfie et al. THORAX
- Diesel exhaust augments allergen-induced lower airway inflammation in allergic individuals: a controlled human exposure study
- (2015) Chris Carlsten et al. THORAX
- Inflammasomes in COPD and neutrophilic asthma
- (2015) Richard Y Kim et al. THORAX
- Fibulin1C peptide induces cell attachment and extracellular matrix deposition in lung fibroblasts
- (2015) Qi Ge et al. Scientific Reports
- Antagonism of miR-328 Increases the Antimicrobial Function of Macrophages and Neutrophils and Rapid Clearance of Non-typeable Haemophilus Influenzae (NTHi) from Infected Lung
- (2015) Hock L. Tay et al. PLoS Pathogens
- MicroRNA Expression Is Altered in an Ovalbumin-Induced Asthma Model and Targeting miR-155 with Antagomirs Reveals Cellular Specificity
- (2015) Maximilian W. Plank et al. PLoS One
- Adults face increased asthma risk after infant RSV bronchiolitis and reduced respiratory health-related quality of life after RSV pneumonia
- (2014) Katri Backman et al. ACTA PAEDIATRICA
- Patients with Asthma Demonstrate Airway Inflammation after Exposure to Concentrated Ambient Particulate Matter
- (2014) Neil E. Alexis et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Animal models of chronic obstructive pulmonary disease
- (2014) Michael Fricker et al. Expert Opinion on Drug Discovery
- Group 2 Innate Lymphoid Cells Are Critical for the Initiation of Adaptive T Helper 2 Cell-Mediated Allergic Lung Inflammation
- (2014) Timotheus Y.F. Halim et al. IMMUNITY
- Group 2 innate lymphoid cells facilitate sensitization to local, but not systemic, TH2-inducing allergen exposures
- (2014) Matthew J. Gold et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Importance of Mast Cell Prss31/Transmembrane Tryptase/Tryptase-γ in Lung Function and Experimental Chronic Obstructive Pulmonary Disease and Colitis
- (2014) Philip M. Hansbro et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2014) G. E. Kaiko et al. JOURNAL OF IMMUNOLOGY
- TH17 Cells Mediate Steroid-Resistant Airway Inflammation and Airway Hyperresponsiveness in Mice
- (2014) L. McKinley et al. JOURNAL OF IMMUNOLOGY
- The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation
- (2014) Bernardo S Franklin et al. NATURE IMMUNOLOGY
- Effects of ultrafine particles on the allergic inflammation in the lung of asthmatics: results of a double-blinded randomized cross-over clinical pilot study
- (2014) Frank Schaumann et al. Particle and Fibre Toxicology
- LF-15 & T7, Synthetic Peptides Derived from Tumstatin, Attenuate Aspects of Airway Remodelling in a Murine Model of Chronic OVA-Induced Allergic Airway Disease
- (2014) Karryn T. Grafton et al. PLoS One
- Potentially Pathogenic Airway Bacteria and Neutrophilic Inflammation in Treatment Resistant Severe Asthma
- (2014) Benjamin J. Green et al. PLoS One
- Transcriptomics identified a critical role for Th2 cell-intrinsic miR-155 in mediating allergy and antihelminth immunity
- (2014) I. S. Okoye et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Rhinovirus-induced IL-25 in asthma exacerbation drives type 2 immunity and allergic pulmonary inflammation
- (2014) J. Beale et al. Science Translational Medicine
- Corticosteroid Resistance in Pulmonary Neutrophilic Inflammatory Disorders and Rationale for Adjunct IL-1β Targeted Therapy
- (2013) Alan A. Wanderer AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Activity and expression of histone acetylases and deacetylases in inflammatory phenotypes of asthma
- (2013) L. P. Gunawardhana et al. CLINICAL AND EXPERIMENTAL ALLERGY
- Airway epithelial regulation of pulmonary immune homeostasis and inflammation
- (2013) Teal S. Hallstrand et al. CLINICAL IMMUNOLOGY
- Programming of the Lung in Early Life by Bacterial Infections Predisposes to Chronic Respiratory Disease
- (2013) MALCOLM R. STARKEY et al. CLINICAL OBSTETRICS AND GYNECOLOGY
- Murine models of infectious exacerbations of airway inflammation
- (2013) Malcolm Ronald Starkey et al. CURRENT OPINION IN PHARMACOLOGY
- MicroRNA Expression in Response to Controlled Exposure to Diesel Exhaust: Attenuation by the Antioxidant N -Acetylcysteine in a Randomized Crossover Study
- (2013) Masatsugu Yamamoto et al. ENVIRONMENTAL HEALTH PERSPECTIVES
- Elevated expression of the NLRP3 inflammasome in neutrophilic asthma
- (2013) J. L. Simpson et al. EUROPEAN RESPIRATORY JOURNAL
- International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma
- (2013) K. F. Chung et al. EUROPEAN RESPIRATORY JOURNAL
- The emerging role of microRNAs in regulating immune and inflammatory responses in the lung
- (2013) Paul S. Foster et al. IMMUNOLOGICAL REVIEWS
- Toll-like receptor 7 gene deficiency and early-life Pneumovirus infection interact to predispose toward the development of asthma-like pathology in mice
- (2013) Gerard E. Kaiko et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- A new short-term mouse model of chronic obstructive pulmonary disease identifies a role for mast cell tryptase in pathogenesis
- (2013) Emma L. Beckett et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- MicroRNA-155 is essential for TH2-mediated allergen-induced eosinophilic inflammation in the lung
- (2013) Carina Malmhäll et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Pneumococcal Components Induce Regulatory T Cells That Attenuate the Development of Allergic Airways Disease by Deviating and Suppressing the Immune Response to Allergen
- (2013) A. N. Thorburn et al. JOURNAL OF IMMUNOLOGY
- MicroRNA-375 Regulation of Thymic Stromal Lymphopoietin by Diesel Exhaust Particles and Ambient Particulate Matter in Human Bronchial Epithelial Cells
- (2013) B. Bleck et al. JOURNAL OF IMMUNOLOGY
- Tumor necrosis factor-related apoptosis-inducing ligand translates neonatal respiratory infection into chronic lung disease
- (2013) M R Starkey et al. Mucosal Immunology
- Interleukin-17–producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity
- (2013) Hye Young Kim et al. NATURE MEDICINE
- Nontypeable Haemophilus Influenzae Infection Upregulates the NLRP3 Inflammasome and Leads to Caspase-1-Dependent Secretion of Interleukin-1β — A Possible Pathway of Exacerbations in COPD
- (2013) Johannes Rotta detto Loria et al. PLoS One
- Association of hospitalizations for asthma with seasonal and pandemic influenza
- (2013) Alicia K. Gerke et al. RESPIROLOGY
- Macrolides for yet another chronic airway disease: severe asthma?
- (2013) Peter G Gibson THORAX
- Probiotic supplementation during pregnancy or infancy for the prevention of asthma and wheeze: systematic review and meta-analysis
- (2013) M. B. Azad et al. BMJ-British Medical Journal
- Severe Asthma: An Expanding and Mounting Clinical Challenge
- (2013) Matthew C. Bell et al. Journal of Allergy and Clinical Immunology-In Practice
- Obesity in asthma: more neutrophilic inflammation as a possible explanation for a reduced treatment response
- (2012) E. D. Telenga et al. ALLERGY
- Airway Epithelial miRNA Expression Is Altered in Asthma
- (2012) Owen D. Solberg et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Airborne Indoor Particles from Schools Are More Toxic than Outdoor Particles
- (2012) Sebastian Oeder et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- The Neutrophilic Inflammatory Phenotype Is Associated With Systemic Inflammation in Asthma
- (2012) Lisa G. Wood et al. CHEST
- Human airway epithelial cell innate immunity: relevance to asthma
- (2012) Jeremy A Hirota et al. CURRENT OPINION IN IMMUNOLOGY
- Th2 cytokine antagonists: potential treatments for severe asthma
- (2012) Philip M Hansbro et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Retinoic-Acid-Receptor-Related Orphan Nuclear Receptor Alpha Is Required for Natural Helper Cell Development and Allergic Inflammation
- (2012) Timotheus Y.F. Halim et al. IMMUNITY
- The airway epithelium nucleotide-binding domain and leucine-rich repeat protein 3 inflammasome is activated by urban particulate matter
- (2012) Jeremy A. Hirota et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- The glutathione-S-transferase mu 1 (GSTM1) null genotype and increased neutrophil response to low-level ozone (0.06 ppm)
- (2012) Neil E. Alexis et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Analysis of NLRP3 in the Development of Allergic Airway Disease in Mice
- (2012) I. C. Allen et al. JOURNAL OF IMMUNOLOGY
- Components of Streptococcus pneumoniae Suppress Allergic Airways Disease and NKT Cells by Inducing Regulatory T Cells
- (2012) A. N. Thorburn et al. JOURNAL OF IMMUNOLOGY
- Emerging roles of pulmonary macrophages in driving the development of severe asthma
- (2012) M. Yang et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Constitutive production of IL-13 promotes early-life Chlamydia respiratory infection and allergic airway disease
- (2012) M R Starkey et al. Mucosal Immunology
- IL-33 mediates multi-walled carbon nanotube (MWCNT)-induced airway hyper-reactivity via the mobilization of innate helper cells in the lung
- (2012) Celine A. Beamer et al. Nanotoxicology
- Elevated risk of asthma after hospitalization for respiratory syncytial virus infection in infancy
- (2012) Shelagh M. Szabo et al. Paediatric Respiratory Reviews
- Diesel exhaust increases EGFR and phosphorylated C-terminal Tyr 1173 in the bronchial epithelium
- (2012) Jamshid Pourazar et al. Particle and Fibre Toxicology
- TLR2/MyD88/NF-κB Pathway, Reactive Oxygen Species, Potassium Efflux Activates NLRP3/ASC Inflammasome during Respiratory Syncytial Virus Infection
- (2012) Jesus Segovia et al. PLoS One
- TLR2, but Not TLR4, Is Required for Effective Host Defence against Chlamydia Respiratory Tract Infection in Early Life
- (2012) Emma L. Beckett et al. PLoS One
- Chlamydia pneumoniae-Specific IgE Is Prevalent in Asthma and Is Associated with Disease Severity
- (2012) David L. Hahn et al. PLoS One
- Chlamydia muridarum Lung Infection in Infants Alters Hematopoietic Cells to Promote Allergic Airway Disease in Mice
- (2012) Malcolm R. Starkey et al. PLoS One
- CombinedHaemophilus influenzaerespiratory infection and allergic airways disease drives chronic infection and features of neutrophilic asthma
- (2012) Ama-Tawiah Essilfie et al. THORAX
- NLRP3 inflammasome is required in murine asthma in the absence of aluminum adjuvant
- (2011) A.-G. Besnard et al. ALLERGY
- Innate Immunity in the Respiratory Epithelium
- (2011) Dane Parker et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Radical-Containing Particles Activate Dendritic Cells and Enhance Th17 Inflammation in a Mouse Model of Asthma
- (2011) Pingli Wang et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Cytokine/anti-cytokine therapy - novel treatments for asthma?
- (2011) Philip M Hansbro et al. BRITISH JOURNAL OF PHARMACOLOGY
- Ambient Particulate Matter Induces Interleukin-8 Expression through an Alternative NF-κB (Nuclear Factor-Kappa B) Mechanism in Human Airway Epithelial Cells
- (2011) Robert Silbajoris et al. ENVIRONMENTAL HEALTH PERSPECTIVES
- TACE/TGF- /EGFR regulates CXCL8 in bronchial epithelial cells exposed to particulate matter components
- (2011) J. Ovrevik et al. EUROPEAN RESPIRATORY JOURNAL
- Airway inflammation is augmented by obesity and fatty acids in asthma
- (2011) H. A. Scott et al. EUROPEAN RESPIRATORY JOURNAL
- An Unexpected Role for Uric Acid as an Inducer of T Helper 2 Cell Immunity to Inhaled Antigens and Inflammatory Mediator of Allergic Asthma
- (2011) Mirjam Kool et al. IMMUNITY
- The Air Pollution Exposure Laboratory (APEL) for controlled human exposure to diesel exhaust and other inhalants: characterization and comparison to existing facilities
- (2011) Nicholas Birger et al. INHALATION TOXICOLOGY
- Transcriptional phenotypes of asthma defined by gene expression profiling of induced sputum samples
- (2011) Katherine J. Baines et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- A high-fat challenge increases airway inflammation and impairs bronchodilator recovery in asthma
- (2011) Lisa G. Wood et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Monocyte-derived dendritic cell recruitment and allergic TH2 responses after exposure to diesel particles are CCR2 dependent
- (2011) Sharen Provoost et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Effects of air pollutants on innate immunity: The role of Toll-like receptors and nucleotide-binding oligomerization domain–like receptors
- (2011) Rebecca N. Bauer et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Biochemical Basis of Asthma Therapy
- (2011) Peter J. Barnes JOURNAL OF BIOLOGICAL CHEMISTRY
- MicroRNA-21 Limits In Vivo Immune Response-Mediated Activation of the IL-12/IFN- Pathway, Th1 Polarization, and the Severity of Delayed-Type Hypersensitivity
- (2011) T. X. Lu et al. JOURNAL OF IMMUNOLOGY
- Neonatal chlamydial pneumonia induces altered respiratory structure and function lasting into adult life
- (2011) Madhulika Jupelli et al. LABORATORY INVESTIGATION
- The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
- (2011) Bolormaa Vandanmagsar et al. NATURE MEDICINE
- Inflammasome-IL-1-Th17 response in allergic lung inflammation
- (2011) A.-G. Besnard et al. Journal of Molecular Cell Biology
- Interleukin-13 Promotes Susceptibility to Chlamydial Infection of the Respiratory and Genital Tracts
- (2011) Kelly L. Asquith et al. PLoS Pathogens
- Haemophilus influenzae Infection Drives IL-17-Mediated Neutrophilic Allergic Airways Disease
- (2011) Ama-Tawiah Essilfie et al. PLoS Pathogens
- Orange juice neutralizes the proinflammatory effect of a high-fat, high-carbohydrate meal and prevents endotoxin increase and Toll-like receptor expression
- (2010) Husam Ghanim et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Targeting Phosphoinositide-3-Kinase-δ with Theophylline Reverses Corticosteroid Insensitivity in Chronic Obstructive Pulmonary Disease
- (2010) Yasuo To et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Harnessing Regulatory T cells to Suppress Asthma
- (2010) Alison N. Thorburn et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- A Potential Role for P2X7R in Allergic Airway Inflammation in Mice and Humans
- (2010) Tobias Müller et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- TH17 Cells in Asthma and COPD
- (2010) John F. Alcorn et al. Annual Review of Physiology
- The Inflammasomes
- (2010) Kate Schroder et al. CELL
- Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease
- (2010) Gökhan S. Hotamisligil CELL
- The ‘hygiene hypothesis’ for autoimmune and allergic diseases: an update
- (2010) H. Okada et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Potential Therapeutic Targets for Steroid-Resistant Asthma
- (2010) Wan Wang et al. CURRENT DRUG TARGETS
- Critical functions of priming and lysosomal damage for NLRP3 activation
- (2010) Veit Hornung et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Streptococcus pneumoniae infection suppresses allergic airways disease by inducing regulatory T-cells
- (2010) J. A. Preston et al. EUROPEAN RESPIRATORY JOURNAL
- Potentially pathogenic bacteria cultured from the sputum of stable asthmatics are associated with increased 8-isoprostane and airway neutrophilia
- (2010) Lisa G. Wood et al. FREE RADICAL RESEARCH
- Ozone activates pulmonary dendritic cells and promotes allergic sensitization through a Toll-like receptor 4–dependent mechanism
- (2010) John W. Hollingsworth et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Atopic asthmatic subjects but not atopic subjects without asthma have enhanced inflammatory response to ozone
- (2010) Michelle L. Hernandez et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Analyses of asthma severity phenotypes and inflammatory proteins in subjects stratified by sputum granulocytes
- (2010) Annette T. Hastie et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Early-life chlamydial lung infection enhances allergic airways disease through age-dependent differences in immunopathology
- (2010) Jay C. Horvat et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Coordinate suppression of B cell lymphoma by PTEN and SHIP phosphatases
- (2010) Ana V. Miletic et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Diesel Exhaust Particle-Treated Human Bronchial Epithelial Cells Upregulate Jagged-1 and OX40 Ligand in Myeloid Dendritic Cells via Thymic Stromal Lymphopoietin
- (2010) B. Bleck et al. JOURNAL OF IMMUNOLOGY
- NK Cell Deficiency Predisposes to Viral-Induced Th2-Type Allergic Inflammation via Epithelial-Derived IL-25
- (2010) G. E. Kaiko et al. JOURNAL OF IMMUNOLOGY
- Inflammation and Fibrosis during Chlamydia pneumoniae Infection Is Regulated by IL-1 and the NLRP3/ASC Inflammasome
- (2010) X. He et al. JOURNAL OF IMMUNOLOGY
- IL-27/IFN- Induce MyD88-Dependent Steroid-Resistant Airway Hyperresponsiveness by Inhibiting Glucocorticoid Signaling in Macrophages
- (2010) J. J. Li et al. JOURNAL OF IMMUNOLOGY
- Chlamydial Respiratory Infection during Allergen Sensitization Drives Neutrophilic Allergic Airways Disease
- (2010) J. C. Horvat et al. JOURNAL OF IMMUNOLOGY
- Activation of Pulmonary Dendritic Cells and Th2-Type Inflammatory Responses on Instillation of Engineered, Environmental Diesel Emission Source or Ambient Air Pollutant Particles in vivo
- (2010) Gillina F.G. Bezemer et al. Journal of Innate Immunity
- Mechanisms and resistance in glucocorticoid control of inflammation
- (2010) Peter J. Barnes JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Influenza virus activates inflammasomes via its intracellular M2 ion channel
- (2010) Takeshi Ichinohe et al. NATURE IMMUNOLOGY
- Infectious Chlamydia pneumoniae is Associated With Elevated Interleukin-8 and Airway Neutrophilia in Children With Refractory Asthma
- (2010) Katir K. Patel et al. PEDIATRIC INFECTIOUS DISEASE JOURNAL
- Fibulin-1 Is Increased in Asthma – A Novel Mediator of Airway Remodeling?
- (2010) Justine Y. Lau et al. PLoS One
- Pneumococcal conjugate vaccine-induced regulatory T cells suppress the development of allergic airways disease
- (2010) A. N. Thorburn et al. THORAX
- Toll-like receptor 2 and 4 genes influence susceptibility to adverse effects of traffic-related air pollution on childhood asthma
- (2010) M. Kerkhof et al. THORAX
- Asthma and allergy patterns over 18 years after severe RSV bronchiolitis in the first year of life
- (2010) N. Sigurs et al. THORAX
- Inhibition of PI3Kδ Restores Glucocorticoid Function in Smoking-induced Airway Inflammation in Mice
- (2009) John A. Marwick et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Reduction of Tumstatin in Asthmatic Airways Contributes to Angiogenesis, Inflammation, and Hyperresponsiveness
- (2009) Janette K. Burgess et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Diesel Particle–Induced Transcriptional Expression of p21 Involves Activation of EGFR, Src, and Stat3
- (2009) Dongsun Cao et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- The Inflammasomes: Guardians of the Body
- (2009) Fabio Martinon et al. Annual Review of Immunology
- Aberrant overexpression of microRNAs activate AKT signaling via down-regulation of tumor suppressors in natural killer-cell lymphoma/leukemia
- (2009) Y. Yamanaka et al. BLOOD
- MicroRNAs: Target Recognition and Regulatory Functions
- (2009) David P. Bartel CELL
- The Adjuvant Effect of Ambient Particulate Matter Is Closely Reflected by the Particulate Oxidant Potential
- (2009) Ning Li et al. ENVIRONMENTAL HEALTH PERSPECTIVES
- Differential gene expression and cytokine production from neutrophils in asthma phenotypes
- (2009) K. J. Baines et al. EUROPEAN RESPIRATORY JOURNAL
- Allergic airway hyperresponsiveness, inflammation, and remodeling do not develop in phosphoinositide 3-kinase γ–deficient mice
- (2009) Masahide Takeda et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Inflammasomes: too big to miss
- (2009) Andrea Stutz et al. JOURNAL OF CLINICAL INVESTIGATION
- Diesel Exhaust Particles Stimulate Adaptive Immunity by Acting on Pulmonary Dendritic Cells
- (2009) Sharen Provoost et al. JOURNAL OF IMMUNOLOGY
- Pathogenesis of Steroid-Resistant Airway Hyperresponsiveness: Interaction between IFN- and TLR4/MyD88 Pathways
- (2009) M. Yang et al. JOURNAL OF IMMUNOLOGY
- MicroRNA-21 Is Up-Regulated in Allergic Airway Inflammation and Regulates IL-12p35 Expression
- (2009) T. X. Lu et al. JOURNAL OF IMMUNOLOGY
- Glucocorticoid resistance in inflammatory diseases
- (2009) Peter J Barnes et al. LANCET
- AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
- (2009) Teresa Fernandes-Alnemri et al. NATURE
- AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
- (2009) Veit Hornung et al. NATURE
- Many roads to maturity: microRNA biogenesis pathways and their regulation
- (2009) Julia Winter et al. NATURE CELL BIOLOGY
- An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome
- (2009) Tilmann Bürckstümmer et al. NATURE IMMUNOLOGY
- Asthma
- (2009) Christopher H. Fanta NEW ENGLAND JOURNAL OF MEDICINE
- Dietary factors lead to innate immune activation in asthma
- (2009) Lisa G. Wood et al. PHARMACOLOGY & THERAPEUTICS
- Antagonism of microRNA-126 suppresses the effector function of TH2 cells and the development of allergic airways disease
- (2009) J. Mattes et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Airway inflammation in obese and nonobese patients with difficult-to-treat asthma
- (2008) I. H. van Veen et al. ALLERGY
- Ozone inhalation induces exacerbation of eosinophilic airway inflammation and hyperresponsiveness in allergen-sensitized mice
- (2008) S. Kierstein et al. ALLERGY
- PI3Kγ-deficient mice have reduced levels of allergen-induced eosinophilic inflammation and airway remodeling
- (2008) Dae Hyun Lim et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Regulation of COX-2 Expression and IL-6 Release by Particulate Matter in Airway Epithelial Cells
- (2008) Yutong Zhao et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Role of HDAC2 in the Pathophysiology of COPD
- (2008) Peter J. Barnes Annual Review of Physiology
- Obesity and Asthma
- (2008) Andréa Lessard et al. CHEST
- Steroid resistance in asthma: Mechanisms and treatment options
- (2008) Ian M. Adcock et al. CURRENT ALLERGY AND ASTHMA REPORTS
- Phenotypic Switching of Adipose Tissue Macrophages With Obesity Is Generated by Spatiotemporal Differences in Macrophage Subtypes
- (2008) C. N. Lumeng et al. DIABETES
- Adipose tissue dysfunction in obesity, diabetes, and vascular diseases
- (2008) G. R. Hajer et al. EUROPEAN HEART JOURNAL
- Occurrence of Chlamydia trachomatis and Chlamydia pneumoniae in paediatric respiratory infections
- (2008) W. C. Webley et al. EUROPEAN RESPIRATORY JOURNAL
- Diesel exhaust exposure enhances the ozone-induced airway inflammation in healthy humans
- (2008) J. Bosson et al. EUROPEAN RESPIRATORY JOURNAL
- Effects of Particulate Matter on Cytokine Production In Vitro: A Comparative Analysis of Published Studies
- (2008) S. Mitschik et al. INHALATION TOXICOLOGY
- Cigarette smoke extract induces thymic stromal lymphopoietin expression, leading to TH2-type immune responses and airway inflammation
- (2008) Yuki Nakamura et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants
- (2008) Stephanie C. Eisenbarth et al. NATURE
- Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
- (2008) Veit Hornung et al. NATURE IMMUNOLOGY
- The PTEN–PI3K pathway: of feedbacks and cross-talks
- (2008) A Carracedo et al. ONCOGENE
- Understanding the mechanisms of viral induced asthma: New therapeutic directions
- (2008) Nicole G. Hansbro et al. PHARMACOLOGY & THERAPEUTICS
- Clarithromycin Targets Neutrophilic Airway Inflammation in Refractory Asthma
- (2007) Jodie L. Simpson et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Differences in Airway Cytokine Profile in Severe Asthma Compared to Moderate Asthma
- (2007) Joanne Shannon et al. CHEST
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