Roles of Autophagy and Autophagy-Related Proteins in Antifungal Immunity

B cell autophagy mediates TLR7-dependent autoimmunity and inflammation

(2015) Chi G Weindel et al.   Autophagy

TNFAIP3 promotes survival of CD4 T cells by restricting MTOR and promoting autophagy

(2015) Yu Matsuzawa et al.   Autophagy

Retinoic acid-induced IgG production in TLR-activated human primary B cells involves ULK1-mediated autophagy

(2015) Agnete Bratsberg Eriksen et al.   Autophagy

ATG16L1: A multifunctional susceptibility factor in Crohn disease

(2015) Mohammad Salem et al.   Autophagy

Concerted Activation of the AIM2 and NLRP3 Inflammasomes Orchestrates Host Protection against Aspergillus Infection

(2015) Rajendra Karki et al.   Cell Host & Microbe

Neutrophil extracellular trap formation is associated with autophagy-related signalling in ANCA-associated vasculitis

(2015) S. Tang et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

KIM-1-/TIM-1-mediated phagocytosis links ATG5-/ULK1-dependent clearance of apoptotic cells to antigen presentation

(2015) C. R. Brooks et al.   EMBO JOURNAL

The Lung Is Protected from Spontaneous Inflammation by Autophagy in Myeloid Cells

(2015) Masashi Kanayama et al.   JOURNAL OF IMMUNOLOGY

Requirement for Autophagy in the Long-Term Persistence but not Initial Formation of Memory B cells

(2015) Min Chen et al.   JOURNAL OF IMMUNOLOGY

B Lymphocytes Are Required during the Early Priming of CD4+T Cells for Clearance ofPneumocystisInfection in Mice

(2015) Michael M. Opata et al.   JOURNAL OF IMMUNOLOGY

Survival of Effector CD8+T Cells during Influenza Infection Is Dependent on Autophagy

(2015) Katrin Schlie et al.   JOURNAL OF IMMUNOLOGY

Unique role for ATG5 in neutrophil-mediated immunopathology during M. tuberculosis infection

(2015) Jacqueline M. Kimmey et al.   NATURE

Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins

(2015) Jennifer Martinez et al.   NATURE CELL BIOLOGY

Autophagy enhances NFκB activity in specific tissue macrophages by sequestering A20 to boost antifungal immunity

(2015) Masashi Kanayama et al.   Nature Communications

Dectin-1–Dependent LC3 Recruitment to Phagosomes Enhances Fungicidal Activity in Macrophages

(2014) Jenny M. Tam et al.   JOURNAL OF INFECTIOUS DISEASES

Role of autophagy genetic variants for the risk of Candida infections

(2014) D. C. Rosentul et al.   MEDICAL MYCOLOGY

Essential role for autophagy in the maintenance of immunological memory against influenza infection

(2014) Min Chen et al.   NATURE MEDICINE

Self-consumption: the interplay of autophagy and apoptosis

(2014) Guillermo Mariño et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans

(2014) Antonella de Luca et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagy Controls BCG-Induced Trained Immunity and the Response to Intravesical BCG Therapy for Bladder Cancer

(2014) Kathrin Buffen et al.   PLoS Pathogens

Pivotal role for the mTOR pathway in the formation of neutrophil extracellular traps via regulation of autophagy

(2013) Asako Itakura et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Autophagy: a potential therapeutic target in lung diseases

(2013) Kiichi Nakahira et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Autophagy is redundant for the host defense against systemic Candida albicans infections

(2013) S. P. Smeekens et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Corticosteroids Block Autophagy Protein Recruitment in Aspergillus fumigatus Phagosomes via Targeting Dectin-1/Syk Kinase Signaling

(2013) I. Kyrmizi et al.   JOURNAL OF IMMUNOLOGY

Autophagy in Human Health and Disease

(2013) Augustine M.K. Choi et al.   NEW ENGLAND JOURNAL OF MEDICINE

NADPH Oxidase-Driven Phagocyte Recruitment Controls Candida albicans Filamentous Growth and Prevents Mortality

(2013) Kimberly M. Brothers et al.   PLoS Pathogens

Autophagy and the Immune System

(2012) Petric Kuballa et al.   Annual Review of Immunology

Invasive fungal infection in chronic granulomatous disease

(2012) E. Liana Falcone et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Role of autophagy in immunity and autoimmunity, with a special focus on systemic lupus erythematosus

(2012) Marina Pierdominici et al.   FASEB JOURNAL

Selective Autophagy of the Adaptor Protein Bcl10 Modulates T Cell Receptor Activation of NF-κB

(2012) Suman Paul et al.   IMMUNITY

Macrophage Autophagy in Immunity to Cryptococcus neoformans and Candida albicans

(2012) André Moraes Nicola et al.   INFECTION AND IMMUNITY

Fungal infection and increased mortality in patients with chronic granulomatous disease

(2012) S. Bassiri-Jahromi et al.   JOURNAL DE MYCOLOGIE MEDICALE

Dectin-1-triggered Recruitment of Light Chain 3 Protein to Phagosomes Facilitates Major Histocompatibility Complex Class II Presentation of Fungal-derived Antigens

(2012) Jun Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Characterization of the Early B Cell Response to Pulmonary Cryptococcus neoformans Infection

(2012) S. Rohatgi et al.   JOURNAL OF IMMUNOLOGY

Trends in the prevalence of invasive fungal infections from an analysis of annual records of autopsy cases of Toho University

(2012) Kayoko Shimodaira et al.   MYCOSES

Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction

(2012) Chong-Shan Shi et al.   NATURE IMMUNOLOGY

Hidden Killers: Human Fungal Infections

(2012) G. D. Brown et al.   Science Translational Medicine

Association of IRGM Polymorphisms and Susceptibility to Pulmonary Tuberculosis in Zahedan, Southeast Iran

(2012) Gholamreza Bahari et al.   TheScientificWorldJOURNAL

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

Current Concepts of Hyperinflammation in Chronic Granulomatous Disease

(2011) Nikolaus Rieber et al.   Clinical & Developmental Immunology

Autophagy and cytokines

(2011) James Harris   CYTOKINE

The inflammasome drives protective Th1 and Th17 cellular responses in disseminated candidiasis

(2011) Frank L. van de Veerdonk et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Autophagy machinery mediates macroendocytic processing and entotic cell death by targeting single membranes

(2011) Oliver Florey et al.   NATURE CELL BIOLOGY

Expression of A20 by dendritic cells preserves immune homeostasis and prevents colitis and spondyloarthritis

(2011) Gianna Elena Hammer et al.   NATURE IMMUNOLOGY

Chaperone-mediated autophagy: Dice's 'wild' idea about lysosomal selectivity

(2011) Ana Maria Cuervo   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Autophagy differentially controls plant basal immunity to biotrophic and necrotrophic pathogens

(2011) Heike D. Lenz et al.   PLANT JOURNAL

Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells

(2011) J. Martinez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional Analysis of Host Factors that Mediate the Intracellular Lifestyle of Cryptococcus neoformans

(2011) Qing-Ming Qin et al.   PLoS Pathogens

Inflammasome activation in NADPH oxidase defective mononuclear phagocytes from patients with chronic granulomatous disease

(2010) F. Meissner et al.   BLOOD

Neutrophil extracellular trap cell death requires both autophagy and superoxide generation

(2010) Quinten Remijsen et al.   CELL RESEARCH

Identification of a novel IRGM promoter single nucleotide polymorphism associated with tuberculosis

(2010) Nanying Che et al.   CLINICA CHIMICA ACTA

The role of PI3P phosphatases in the regulation of autophagy

(2010) Isabelle Vergne et al.   FEBS LETTERS

In Vivo Requirement for Atg5 in Antigen Presentation by Dendritic Cells

(2010) Heung Kyu Lee et al.   IMMUNITY

The Absence of Serum IgM Enhances the Susceptibility of Mice to Pulmonary Challenge with Cryptococcus neoformans

(2010) K. S. Subramaniam et al.   JOURNAL OF IMMUNOLOGY

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

Reactive oxygen species-independent activation of the IL-1  inflammasome in cells from patients with chronic granulomatous disease

(2010) F. L. van de Veerdonk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TRAF6 and A20 Regulate Lysine 63-Linked Ubiquitination of Beclin-1 to Control TLR4-Induced Autophagy

(2010) C. S. Shi et al.   Science Signaling

Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis

(2009) Heather R. Conti et al.   JOURNAL OF EXPERIMENTAL MEDICINE

ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery

(2009) Chang Hwa Jung et al.   MOLECULAR BIOLOGY OF THE CELL

Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence

(2009) Olaf Gross et al.   NATURE

Aspergillus to Zygomycetes: Causes, Risk Factors, Prevention, and Treatment of Invasive Fungal Infections

(2008) O. A. Cornely   INFECTION