Sumoylated SnoN interacts with HDAC1 and p300/CBP to regulate EMT-associated phenotypes in mammary organoids

HDAC inhibition induces EMT and alterations in cellular iron homeostasis to augment ferroptosis sensitivity in SW13 cells

(2021) Thais Oliveira et al.   Redox Biology

Transcription co-activator P300 activates Elk1-aPKC-ι signaling mediated epithelial-to-mesenchymal transition and malignancy in hepatocellular carcinoma

(2020) Chaoqun Ma et al.   Oncogenesis

A potent CBP/p300-Snail interaction inhibitor suppresses tumor growth and metastasis in wild-type p53-expressing cancer

(2020) Hong-Mei Li et al.   Science Advances

PIAS1 and TIF1γ collaborate to promote SnoN SUMOylation and suppression of epithelial–mesenchymal transition

(2020) Ayan Chanda et al.   CELL DEATH AND DIFFERENTIATION

Histone Deacetylases Inhibit the Snail2-Mediated EMT During Metastasis of Hepatocellular Carcinoma Cells

(2020) Yue Hu et al.   Frontiers in Cell and Developmental Biology

Garcinol inhibits esophageal cancer metastasis by suppressing the p300 and TGF-β1 signaling pathways

(2019) Jing Wang et al.   ACTA PHARMACOLOGICA SINICA

Recombinant human PRG4 (rhPRG4) suppresses breast cancer cell invasion by inhibiting TGFβ-Hyaluronan-CD44 signalling pathway

(2019) Anusi Sarkar et al.   PLoS One

Identification of the SUMO E3 ligase PIAS1 as a potential survival biomarker in breast cancer

(2017) Ayan Chanda et al.   PLoS One

The PIAS3-Smurf2 sumoylation pathway suppresses breast cancer organoid invasiveness

(2017) Amrita Singh Chandhoke et al.   Oncotarget

SnoN Stabilizes the SMAD3/SMAD4 Protein Complex

(2017) Karin Walldén et al.   Scientific Reports

EMT: 2016

(2016) M. Angela Nieto et al.   CELL

P300 promotes migration, invasion and epithelial-mesenchymal transition in a nasopharyngeal carcinoma cell line

(2016) Zhi-Wei Liao et al.   Oncology Letters

HDACs and HDAC Inhibitors in Cancer Development and Therapy

(2016) Yixuan Li et al.   Cold Spring Harbor Perspectives in Medicine

Mechanisms of TGFβ-Induced Epithelial–Mesenchymal Transition

(2016) Aristidis Moustakas et al.   Journal of Clinical Medicine

The ubiquitin ligase Smurf2 suppresses TGFβ-induced epithelial–mesenchymal transition in a sumoylation-regulated manner

(2015) A S Chandhoke et al.   CELL DEATH AND DIFFERENTIATION

Epithelial–Mesenchymal Plasticity: A Central Regulator of Cancer Progression

(2015) Xin Ye et al.   TRENDS IN CELL BIOLOGY

Inhibition of p300 suppresses growth of breast cancer. Role of p300 subcellular localization

(2014) María E. Fermento et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Inhibition of Epithelial to Mesenchymal Transition by E-cadherin Up-regulation via Repression of Slug Transcription and Inhibition of E-cadherin Degradation

(2014) Arghya Adhikary et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TIF1γ Protein Regulates Epithelial-Mesenchymal Transition by Operating as a Small Ubiquitin-like Modifier (SUMO) E3 Ligase for the Transcriptional Regulator SnoN1

(2014) Yoshiho Ikeuchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Replication

(2014) Paul Blainey et al.   NATURE METHODS

Identification of a Novel Link between the Protein Kinase NDR1 and TGFβ Signaling in Epithelial Cells

(2013) Isabelle Pot et al.   PLoS One

The role of epithelial–mesenchymal transition programming in invasion and metastasis: a clinical perspective

(2013) Chad Creighton et al.   Cancer Management and Research

SnoN signaling in proliferating cells and postmitotic neurons

(2012) Shirin Bonni et al.   FEBS LETTERS

SnoN oncoprotein enhances estrogen receptor-α transcriptional activity

(2011) Arja M. Band et al.   CELLULAR SIGNALLING

High expression of p300 in human breast cancer correlates with tumor recurrence and predicts adverse prognosis

(2011) Xiang-sheng Xiao et al.   Chinese Journal of Cancer Research

Suppression of TGFβ-Induced Epithelial-Mesenchymal Transition Like Phenotype by a PIAS1 Regulated Sumoylation Pathway in NMuMG Epithelial Cells

(2010) Stuart J. Netherton et al.   PLoS One

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

TGF-β-induced epithelial to mesenchymal transition

(2009) Jian Xu et al.   CELL RESEARCH

EMT: When epithelial cells decide to become mesenchymal-like cells

(2009) Raghu Kalluri   JOURNAL OF CLINICAL INVESTIGATION

A SnoN-Ccd1 Pathway Promotes Axonal Morphogenesis in the Mammalian Brain

(2009) Y. Ikeuchi et al.   JOURNAL OF NEUROSCIENCE

Ski and SnoN, potent negative regulators of TGF-β signaling

(2008) Julien Deheuninck et al.   CELL RESEARCH