The ubiquitin ligase Smurf2 suppresses TGFβ-induced epithelial–mesenchymal transition in a sumoylation-regulated manner

TIF1γ Protein Regulates Epithelial-Mesenchymal Transition by Operating as a Small Ubiquitin-like Modifier (SUMO) E3 Ligase for the Transcriptional Regulator SnoN1

(2014) Yoshiho Ikeuchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of Smurf2 translation by miR-322/503 modulates TGF-β/Smad2 signaling and intestinal epithelial homeostasis

(2014) Shan Cao et al.   MOLECULAR BIOLOGY OF THE CELL

Itch E3 Ubiquitin Ligase Positively Regulates TGF-β Signaling to EMT via Smad7 Ubiquitination

(2014) Su-hyun Park et al.   MOLECULES AND CELLS

Smurf2-mediated degradation of EZH2 enhances neuron differentiation and improves functional recovery after ischaemic stroke

(2013) Yung-Luen Yu et al.   EMBO Molecular Medicine

SMURF1 Plays a role in EGF-induced breast cancer cell migration and invasion

(2013) Arang Kwon et al.   MOLECULES AND CELLS

Identification of a Novel Link between the Protein Kinase NDR1 and TGFβ Signaling in Epithelial Cells

(2013) Isabelle Pot et al.   PLoS One

Overexpression of Smad ubiquitin regulatory factor 2 suppresses transforming growth factor-β mediated liver fibrosis

(2012) Yu CAI et al.   Journal of Digestive Diseases

Function and regulation of SUMO proteases

(2012) Christopher M. Hickey et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Identification of a Novel Function for the Chromatin Remodeling Protein ING2 in Muscle Differentiation

(2012) Shawn A. Eapen et al.   PLoS One

Smurf2-mediated ubiquitination and degradation of Id1 regulates p16 expression during senescence

(2011) Yahui Kong et al.   AGING CELL

Phosphorylation of Serine 68 of Twist1 by MAPKs Stabilizes Twist1 Protein and Promotes Breast Cancer Cell Invasiveness

(2011) J. Hong et al.   CANCER RESEARCH

Ablation of Smurf2 reveals an inhibition in TGF-β signalling through multiple mono-ubiquitination of Smad3

(2011) Liu-Ya Tang et al.   EMBO JOURNAL

An Isoform-Specific SnoN1-FOXO1 Repressor Complex Controls Neuronal Morphogenesis and Positioning in the Mammalian Brain

(2011) Mai Anh Huynh et al.   NEURON

Matrix compositions and the development of breast acini and ducts in 3D cultures

(2010) Muthulekha Swamydas et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

The Protein Stability of Axin, a Negative Regulator of Wnt Signaling, Is Regulated by Smad Ubiquitination Regulatory Factor 2 (Smurf2)

(2010) Sewoon Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cell Polarity in Motion: Redefining Mammary Tissue Organization Through EMT and Cell Polarity Transitions

(2010) Nathan J. Godde et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Suppression of TGFβ-Induced Epithelial-Mesenchymal Transition Like Phenotype by a PIAS1 Regulated Sumoylation Pathway in NMuMG Epithelial Cells

(2010) Stuart J. Netherton et al.   PLoS One

Regulation of Planar Cell Polarity by Smurf Ubiquitin Ligases

(2009) Masahiro Narimatsu et al.   CELL

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

The morphological and molecular features of the epithelial-to-mesenchymal transition

(2009) Gema Moreno-Bueno et al.   Nature Protocols

Physiological functions of the HECT family of ubiquitin ligases

(2009) Daniela Rotin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Transforming growth factor-β signaling in epithelial-mesenchymal transition and progression of cancer

(2009) Kohei MIYAZONO   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Regulation of TGF-β family signaling by E3 ubiquitin ligases

(2008) Yasumichi Inoue et al.   CANCER SCIENCE

TGFβ in Cancer

(2008) Joan Massagué   CELL

Smad7 Stabilizes β-Catenin Binding to E-cadherin Complex and Promotes Cell-Cell Adhesion

(2008) Yi Tang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Smurf2 Induces Ubiquitin-dependent Degradation of Smurf1 to Prevent Migration of Breast Cancer Cells

(2008) Erina Fukunaga et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SUMOylation and De-SUMOylation: Wrestling with Life's Processes

(2008) Edward T. H. Yeh   JOURNAL OF BIOLOGICAL CHEMISTRY

TGF -Smad2 Signaling Regulates the Cdh1-APC/SnoN Pathway of Axonal Morphogenesis

(2008) J. Stegmuller et al.   JOURNAL OF NEUROSCIENCE

TRAF6 Mediates Smad-Independent Activation of JNK and p38 by TGF-β

(2008) Motozo Yamashita et al.   MOLECULAR CELL