PIAS1 and TIF1γ collaborate to promote SnoN SUMOylation and suppression of epithelial–mesenchymal transition

EMT Subtype Influences Epithelial Plasticity and Mode of Cell Migration

(2018) Nicole M. Aiello et al.   DEVELOPMENTAL CELL

Epithelial-mesenchymal transition in breast epithelial cells treated with cadmium and the role of Snail

(2018) Zhengxi Wei et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The SUMO System and TGFβ Signaling Interplay in Regulation of Epithelial-Mesenchymal Transition: Implications for Cancer Progression

(2018) Ayan Chanda et al.   Cancers

Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation

(2017) Ivo A Hendriks et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Identification of the SUMO E3 ligase PIAS1 as a potential survival biomarker in breast cancer

(2017) Ayan Chanda et al.   PLoS One

Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation

(2017) Ivo A Hendriks et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The PIAS3-Smurf2 sumoylation pathway suppresses breast cancer organoid invasiveness

(2017) Amrita Singh Chandhoke et al.   Oncotarget

SnoN suppresses TGF-β-induced epithelial-mesenchymal transition and invasion of bladder cancer in a TIF1γ-dependent manner

(2016) Xinbao Yin et al.   ONCOLOGY REPORTS

The ubiquitin ligase Smurf2 suppresses TGFβ-induced epithelial–mesenchymal transition in a sumoylation-regulated manner

(2015) A S Chandhoke et al.   CELL DEATH AND DIFFERENTIATION

Epithelial–Mesenchymal Plasticity: A Central Regulator of Cancer Progression

(2015) Xin Ye et al.   TRENDS IN CELL BIOLOGY

TIF1γ Protein Regulates Epithelial-Mesenchymal Transition by Operating as a Small Ubiquitin-like Modifier (SUMO) E3 Ligase for the Transcriptional Regulator SnoN1

(2014) Yoshiho Ikeuchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of TRIML2, a Novel p53 Target, that Enhances p53 SUMOylation and Regulates the Transactivation of Proapoptotic Genes

(2014) Che-Pei Kung et al.   MOLECULAR CANCER RESEARCH

Replication

(2014) Paul Blainey et al.   NATURE METHODS

TIF1  requires sumoylation to exert its repressive activity on TGF  signaling

(2013) L. Fattet et al.   JOURNAL OF CELL SCIENCE

Identification of a Novel Link between the Protein Kinase NDR1 and TGFβ Signaling in Epithelial Cells

(2013) Isabelle Pot et al.   PLoS One

SnoN signaling in proliferating cells and postmitotic neurons

(2012) Shirin Bonni et al.   FEBS LETTERS

SUMOylation in carcinogenesis

(2011) Kira Bettermann et al.   CANCER LETTERS

The microenvironment determines the breast cancer cells' phenotype: organization of MCF7 cells in 3D cultures

(2010) Silva Krause et al.   BMC CANCER

p53 sumoylation: Mechanistic insights from reconstitution studies

(2010) Shwu-Yuan Wu et al.   Epigenetics

Suppression of TGFβ-Induced Epithelial-Mesenchymal Transition Like Phenotype by a PIAS1 Regulated Sumoylation Pathway in NMuMG Epithelial Cells

(2010) Stuart J. Netherton et al.   PLoS One

TGF-β-induced epithelial to mesenchymal transition

(2009) Jian Xu et al.   CELL RESEARCH

PIAS proteins: pleiotropic interactors associated with SUMO

(2009) Miia M. Rytinki et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

A SnoN-Ccd1 Pathway Promotes Axonal Morphogenesis in the Mammalian Brain

(2009) Y. Ikeuchi et al.   JOURNAL OF NEUROSCIENCE

Ski and SnoN, potent negative regulators of TGF-β signaling

(2008) Julien Deheuninck et al.   CELL RESEARCH