标题
The ticking of aging clocks
作者
关键词
-
出版物
TRENDS IN ENDOCRINOLOGY AND METABOLISM
Volume -, Issue -, Pages -
出版商
Elsevier BV
发表日期
2023-10-23
DOI
10.1016/j.tem.2023.09.007
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Loss of epigenetic information as a cause of mammalian aging
- (2023) Jae-Hyun Yang et al. CELL
- Resurrection of endogenous retroviruses during aging reinforces senescence
- (2023) Xiaoqian Liu et al. CELL
- Distinct longevity mechanisms across and within species and their association with aging
- (2023) Alexander Tyshkovskiy et al. CELL
- Aging Fly Cell Atlas identifies exhaustive aging features at cellular resolution
- (2023) Tzu-Chiao Lu et al. SCIENCE
- Engineering longevity—design of a synthetic gene oscillator to slow cellular aging
- (2023) Zhen Zhou et al. SCIENCE
- cGAS–STING drives ageing-related inflammation and neurodegeneration
- (2023) Muhammet F. Gulen et al. NATURE
- Human PBMC scRNA-seq–based aging clocks reveal ribosome to inflammation balance as a single-cell aging hallmark and super longevity
- (2023) Hongming Zhu et al. Science Advances
- A human brain vascular atlas reveals diverse mediators of Alzheimer’s risk
- (2022) Andrew C. Yang et al. NATURE
- Skin senescence: mechanisms and impact on whole-body aging
- (2022) Ana Catarina Franco et al. TRENDS IN MOLECULAR MEDICINE
- Cross-species metabolomic analysis identifies uridine as a potent regeneration promoting factor
- (2022) Zunpeng Liu et al. Cell Discovery
- Comparative transcriptomics reveals circadian and pluripotency networks as two pillars of longevity regulation
- (2022) J. Yuyang Lu et al. Cell Metabolism
- Chemical reprogramming of human somatic cells to pluripotent stem cells
- (2022) Jingyang Guan et al. NATURE
- Somatic genomic changes in single Alzheimer’s disease neurons
- (2022) Michael B. Miller et al. NATURE
- The longitudinal dynamics and natural history of clonal haematopoiesis
- (2022) Margarete A. Fabre et al. NATURE
- Somatic mutation rates scale with lifespan across mammals
- (2022) Alex Cagan et al. NATURE
- Molecular hallmarks of heterochronic parabiosis at single-cell resolution
- (2022) Róbert Pálovics et al. NATURE
- Single-cell analysis of somatic mutations in human bronchial epithelial cells in relation to aging and smoking
- (2022) Zhenqiu Huang et al. NATURE GENETICS
- Measuring biological age using omics data
- (2022) Jarod Rutledge et al. NATURE REVIEWS GENETICS
- Analysis of somatic mutations in 131 human brains reveals aging-associated hypermutability
- (2022) Taejeong Bae et al. SCIENCE
- KCNQ1OT1 promotes genome-wide transposon repression by guiding RNA–DNA triplexes and HP1 binding
- (2022) Xiaoli Zhang et al. NATURE CELL BIOLOGY
- Molecular mapping of interstitial lung disease reveals a phenotypically distinct senescent basal epithelial cell population
- (2021) Daryle J. DePianto et al. JCI Insight
- Potential reversal of epigenetic age using a diet and lifestyle intervention: a pilot randomized clinical trial
- (2021) Kara N. Fitzgerald et al. Aging-US
- A molecular single-cell lung atlas of lethal COVID-19
- (2021) Johannes C. Melms et al. NATURE
- An aged immune system drives senescence and ageing of solid organs
- (2021) Matthew J. Yousefzadeh et al. NATURE
- Single-cell multi-omics analysis of the immune response in COVID-19
- (2021) Emily Stephenson et al. NATURE MEDICINE
- Assessing the rate of aging to monitor aging itself
- (2021) Xian Xia et al. AGEING RESEARCH REVIEWS
- A Metabolomic Aging Clock Using Human Cerebrospinal Fluid
- (2021) Nathan Hwangbo et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Virus-induced senescence is driver and therapeutic target in COVID-19
- (2021) Soyoung Lee et al. NATURE
- Genetic insights into biological mechanisms governing human ovarian ageing
- (2021) Katherine S. Ruth et al. NATURE
- p21 produces a bioactive secretome that places stressed cells under immunosurveillance
- (2021) Ines Sturmlechner et al. SCIENCE
- Single-Cell Transcriptomic Atlas of Primate Ovarian Aging
- (2020) Si Wang et al. CELL
- Personal aging markers and ageotypes revealed by deep longitudinal profiling
- (2020) Sara Ahadi et al. NATURE MEDICINE
- An epigenetic clock for human skeletal muscle
- (2020) Sarah Voisin et al. Journal of Cachexia Sarcopenia and Muscle
- Single-cell analysis reveals different age-related somatic mutation profiles between stem and differentiated cells in human liver
- (2020) K. Brazhnik et al. Science Advances
- Determinants of accelerated metabolomic and epigenetic aging in a UK cohort
- (2020) Oliver Robinson et al. AGING CELL
- T cells with dysfunctional mitochondria induce multimorbidity and premature senescence
- (2020) Gabriela Desdín-Micó et al. SCIENCE
- Inflammatory Signals Induce AT2 Cell-Derived Damage-Associated Transient Progenitors that Mediate Alveolar Regeneration
- (2020) Jinwook Choi et al. Cell Stem Cell
- Senolytic drugs: from discovery to translation
- (2020) J. L. Kirkland et al. JOURNAL OF INTERNAL MEDICINE
- Ageing hallmarks exhibit organ-specific temporal signatures
- (2020) Nicholas Schaum et al. NATURE
- Human Gut Microbiome Aging Clock Based on Taxonomic Profiling and Deep Learning
- (2020) Fedor Galkin et al. iScience
- Data mining of human plasma proteins generates a multitude of highly predictive aging clocks that reflect different aspects of aging
- (2020) Benoit Lehallier et al. AGING CELL
- Underlying features of epigenetic aging clocks in vivo and in vitro
- (2020) Zuyun Liu et al. AGING CELL
- Plasma proteomic profile of age, health span, and all‐cause mortality in older adults
- (2020) Sanish Sathyan et al. AGING CELL
- Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice
- (2020) Azar Asadi Shahmirzadi et al. Cell Metabolism
- The precursor of PI(3,4,5)P3 alleviates aging by activating daf-18(Pten) and independent of daf-16
- (2020) Dawei Shi et al. Nature Communications
- Metabolic Age Based on the BBMRI-NL 1 H-NMR Metabolomics Repository as Biomarker of Age-related Disease
- (2020) Erik B. van den Akker et al. Circulation-Genomic and Precision Medicine
- PsychoAge and SubjAge: development of deep markers of psychological and subjective age using artificial intelligence
- (2020) Alex Zhavoronkov et al. Aging-US
- Reprogramming to recover youthful epigenetic information and restore vision
- (2020) Yuancheng Lu et al. NATURE
- NAD+ metabolism and its roles in cellular processes during ageing
- (2020) Anthony J. Covarrubias et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- A Single-Cell Transcriptomic Atlas of Human Skin Aging
- (2020) Zhiran Zou et al. DEVELOPMENTAL CELL
- DNA methylation GrimAge strongly predicts lifespan and healthspan
- (2019) Ake T. Lu et al. Aging-US
- Blood Biochemistry Analysis to Detect Smoking Status and Quantify Accelerated Aging in Smokers
- (2019) Polina Mamoshina et al. Scientific Reports
- L1 drives IFN in senescent cells and promotes age-associated inflammation
- (2019) Marco De Cecco et al. NATURE
- LINE1 Derepression in Aged Wild-Type and SIRT6-Deficient Mice Drives Inflammation
- (2019) Matthew Simon et al. Cell Metabolism
- Single-cell whole-genome sequencing reveals the functional landscape of somatic mutations in B lymphocytes across the human lifespan
- (2019) Lei Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inflammation-induced DNA damage, mutations and cancer
- (2019) Jennifer Kay et al. DNA REPAIR
- Reversal of epigenetic aging and immunosenescent trends in humans
- (2019) Gregory M. Fahy et al. AGING CELL
- Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing
- (2019) Qian Zhang et al. Genome Medicine
- Longevity in response to lowered insulin signaling requires glycine N‐methyltransferase‐dependent spermidine production
- (2019) Luke S. Tain et al. AGING CELL
- Cardiovascular Disease, Aging, and Clonal Hematopoiesis
- (2019) Megan A. Evans et al. Annual Review of Pathology-Mechanisms of Disease
- Undulating changes in human plasma proteome profiles across the lifespan
- (2019) Benoit Lehallier et al. NATURE MEDICINE
- An epigenetic biomarker of aging for lifespan and healthspan
- (2018) Morgan E. Levine et al. Aging-US
- NAD + Intermediates: The Biology and Therapeutic Potential of NMN and NR
- (2018) Jun Yoshino et al. Cell Metabolism
- Population Specific Biomarkers of Human Aging: A Big Data Study Using South Korean, Canadian, and Eastern European Patient Populations
- (2018) Polina Mamoshina et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Metabolic and inflammatory biomarkers are associated with epigenetic aging acceleration estimates in the GOLDN study
- (2018) Marguerite R. Irvin et al. Clinical Epigenetics
- Machine Learning on Human Muscle Transcriptomic Data for Biomarker Discovery and Tissue-Specific Drug Target Identification
- (2018) Polina Mamoshina et al. Frontiers in Genetics
- Epigenetic clock for skin and blood cells applied to Hutchinson Gilford Progeria Syndrome and ex vivo studies
- (2018) Steve Horvath et al. Aging-US
- Partial reprogramming induces a steady decline in epigenetic age before loss of somatic identity
- (2018) Nelly Olova et al. AGING CELL
- PhotoAgeClock: deep learning algorithms for development of non-invasive visual biomarkers of aging
- (2018) Eugene Bobrov et al. Aging-US
- Predicting brain-age from multimodal imaging data captures cognitive impairment
- (2017) Franziskus Liem et al. NEUROIMAGE
- Predicting Age Using Neuroimaging: Innovative Brain Ageing Biomarkers
- (2017) James H. Cole et al. TRENDS IN NEUROSCIENCES
- Inference of differentiation time for single cell transcriptomes using cell population reference data
- (2017) Na Sun et al. Nature Communications
- DNA methylation signatures in peripheral blood strongly predict all-cause mortality
- (2017) Yan Zhang et al. Nature Communications
- Caloric restriction delays age-related methylation drift
- (2017) Shinji Maegawa et al. Nature Communications
- DNA methylation levels at individual age-associated CpG sites can be indicative for life expectancy
- (2016) Qiong Lin et al. Aging-US
- A Systems Approach to Reverse Engineer Lifespan Extension by Dietary Restriction
- (2016) Lei Hou et al. Cell Metabolism
- Slowing ageing by design: the rise of NAD+ and sirtuin-activating compounds
- (2016) Michael S. Bonkowski et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Epigenetic age acceleration predicts cancer, cardiovascular, and all-cause mortality in a German case cohort
- (2016) Laura Perna et al. Clinical Epigenetics
- Blood Epigenetic Age may Predict Cancer Incidence and Mortality
- (2016) Yinan Zheng et al. EBioMedicine
- DNA methylation age is associated with mortality in a longitudinal Danish twin study
- (2015) Lene Christiansen et al. AGING CELL
- The rate of aging: the rate of deficit accumulation does not change over the adult life span
- (2015) Arnold Mitnitski et al. BIOGERONTOLOGY
- Three-dimensional human facial morphologies as robust aging markers
- (2015) Weiyang Chen et al. CELL RESEARCH
- Measuring Biological Age via Metabonomics: The Metabolic Age Score
- (2015) Johannes Hertel et al. JOURNAL OF PROTEOME RESEARCH
- Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice
- (2015) Jianhui Chang et al. NATURE MEDICINE
- The transcriptional landscape of age in human peripheral blood
- (2015) Marjolein J. Peters et al. Nature Communications
- DNA methylation age of blood predicts all-cause mortality in later life
- (2015) Riccardo E Marioni et al. GENOME BIOLOGY
- Aging of blood can be tracked by DNA methylation changes at just three CpG sites
- (2014) Carola Weidner et al. GENOME BIOLOGY
- Glycans Are a Novel Biomarker of Chronological and Biological Ages
- (2013) Jasminka Krištić et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Hypothalamic programming of systemic ageing involving IKK-β, NF-κB and GnRH
- (2013) Guo Zhang et al. NATURE
- DNA methylation age of human tissues and cell types
- (2013) Steve Horvath GENOME BIOLOGY
- Genome-wide Methylation Profiles Reveal Quantitative Views of Human Aging Rates
- (2012) Gregory Hannum et al. MOLECULAR CELL
- Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
- (2011) Darren J. Baker et al. NATURE
- Epigenetic Predictor of Age
- (2011) Sven Bocklandt et al. PLoS One
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started