Partial reprogramming induces a steady decline in epigenetic age before loss of somatic identity

An epigenetic biomarker of aging for lifespan and healthspan

(2018) Morgan E. Levine et al.   Aging-US

Epigenetic clock for skin and blood cells applied to Hutchinson Gilford Progeria Syndrome and ex vivo studies

(2018) Steve Horvath et al.   Aging-US

Biological Age Predictors

(2017) Juulia Jylhävä et al.   EBioMedicine

In Vivo Amelioration of Age-Associated Hallmarks by Partial Reprogramming

(2016) Alejandro Ocampo et al.   CELL

The epigenetic clock and telomere length are independently associated with chronological age and mortality

(2016) Riccardo E Marioni et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Molecular features of cellular reprogramming and development

(2016) Zachary D. Smith et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A decade of transcription factor-mediated reprogramming to pluripotency

(2016) Kazutoshi Takahashi et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Menopause accelerates biological aging

(2016) Morgan E. Levine et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Disease or Not a Disease? Aging As a Pathology

(2016) Timothy V. Gladyshev et al.   TRENDS IN MOLECULAR MEDICINE

Epigenetic clock analyses of cellular senescence and ageing

(2016) Donna Lowe et al.   Oncotarget

Frailty is associated with the epigenetic clock but not with telomere length in a German cohort

(2016) Lutz Philipp Breitling et al.   Clinical Epigenetics

Epigenetic age acceleration predicts cancer, cardiovascular, and all-cause mortality in a German case cohort

(2016) Laura Perna et al.   Clinical Epigenetics

Dermal fibroblasts induce cell cycle arrest and block epithelial-mesenchymal transition to inhibit the early stage melanoma development

(2016) Linli Zhou et al.   Cancer Medicine

DNA methylation age is associated with mortality in a longitudinal Danish twin study

(2015) Lene Christiansen et al.   AGING CELL

Accelerated epigenetic aging in Down syndrome

(2015) Steve Horvath et al.   AGING CELL

kmlandkml3d:RPackages to Cluster Longitudinal Data

(2015) Christophe Genolini et al.   Journal of Statistical Software

NF-κB activation impairs somatic cell reprogramming in ageing

(2015) Clara Soria-Valles et al.   NATURE CELL BIOLOGY

Human Dermal Fibroblasts Demonstrate Positive Immunostaining for Neuron- and Glia- Specific Proteins

(2015) C. J. Janmaat et al.   PLoS One

DNA methylation age of blood predicts all-cause mortality in later life

(2015) Riccardo E Marioni et al.   GENOME BIOLOGY

Should we treat aging as a disease? The consequences and dangers of miscategorisation

(2015) Richard G. A. Faragher   Frontiers in Genetics

Premature Termination of Reprogramming In Vivo Leads to Cancer Development through Altered Epigenetic Regulation

(2014) Kotaro Ohnishi et al.   CELL

Mesenchymal Stem Cell-Like Properties in Fibroblasts

(2014) Yuqiao Chang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Single Cell Analysis Reveals the Stochastic Phase of Reprogramming to Pluripotency Is an Ordered Probabilistic Process

(2014) Kyung-Min Chung et al.   PLoS One

Dynamic regulation of human endogenous retroviruses mediates factor-induced reprogramming and differentiation potential

(2014) M. Ohnuki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aging of blood can be tracked by DNA methylation changes at just three CpG sites

(2014) Carola Weidner et al.   GENOME BIOLOGY

Reprogramming in vivo produces teratomas and iPS cells with totipotency features

(2013) María Abad et al.   NATURE

Defining the Genomic Signature of Totipotency and Pluripotency during Early Human Development

(2013) Amparo Galan et al.   PLoS One

Maturation, not initiation, is the major roadblock during reprogramming toward pluripotency from human fibroblasts

(2013) K. Tanabe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA methylation age of human tissues and cell types

(2013) Steve Horvath   GENOME BIOLOGY

Methylation ofELOVL2gene as a new epigenetic marker of age

(2012) Paolo Garagnani et al.   AGING CELL

Single-Cell Expression Analyses during Cellular Reprogramming Reveal an Early Stochastic and a Late Hierarchic Phase

(2012) Yosef Buganim et al.   CELL

Epigenetic rejuvenation

(2012) Maria Manukyan et al.   GENES TO CELLS

Genome-wide Methylation Profiles Reveal Quantitative Views of Human Aging Rates

(2012) Gregory Hannum et al.   MOLECULAR CELL

StemCellDB: The Human Pluripotent Stem Cell Database at the National Institutes of Health

(2012) Barbara S. Mallon et al.   Stem Cell Research

Nuclear reprogramming and epigenetic rejuvenation

(2010) Prim B. Singh et al.   JOURNAL OF BIOSCIENCES

Identification of Markers that Distinguish Monocyte-Derived Fibrocytes from Monocytes, Macrophages, and Fibroblasts

(2009) Darrell Pilling et al.   PLoS One

Defining Molecular Cornerstones during Fibroblast to iPS Cell Reprogramming in Mouse

(2008) Matthias Stadtfeld et al.   Cell Stem Cell

Sequential Expression of Pluripotency Markers during Direct Reprogramming of Mouse Somatic Cells

(2008) Tobias Brambrink et al.   Cell Stem Cell

A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types

(2008) Marius Wernig et al.   NATURE BIOTECHNOLOGY