A SAM analogue-utilizing ribozyme for site-specific RNA alkylation in living cells

Efficient in vitro and in vivo RNA editing via recruitment of endogenous ADARs using circular guide RNAs

(2022) Dhruva Katrekar et al.   NATURE BIOTECHNOLOGY

Structural basis for substrate binding and catalysis by a self-alkylating ribozyme

(2022) Daniel Krochmal et al.   Nature Chemical Biology

Chemo-Enzymatic Modification of the 5′ Cap To Study mRNAs

(2022) Amarnath Bollu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Structure and mechanism of the methyltransferase ribozyme MTR1

(2022) Carolin P. M. Scheitl et al.   Nature Chemical Biology

Chemical biology and medicinal chemistry of RNA methyltransferases

(2022) Tim R Fischer et al.   NUCLEIC ACIDS RESEARCH

Methyltransferases: Functions and Applications

(2022) Eman Abdelraheem et al.   CHEMBIOCHEM

Impact of 3-deazapurine nucleobases on RNA properties

(2021) Raphael Bereiter et al.   NUCLEIC ACIDS RESEARCH

Strategies for Covalent Labeling of Long RNAs

(2021) Hannah Depmeier et al.   CHEMBIOCHEM

A natural riboswitch scaffold with self-methylation activity

(2021) Laurin Flemmich et al.   Nature Communications

Propargylic Se-adenosyl-l-selenomethionine: A Chemical Tool for Methylome Analysis

(2021) Yoshihiro Sohtome et al.   ACCOUNTS OF CHEMICAL RESEARCH

The identification and characterization of a selected SAM-dependent methyltransferase ribozyme that is present in natural sequences

(2021) Hengyi Jiang et al.   Nature Catalysis

Repurposing antiviral drugs for orthogonal RNA‐catalyzed labeling of RNA

(2020) Mohammad Ghaem Maghami et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A metabolic labeling method detects m6A transcriptome-wide at single base resolution

(2020) Xiao Shu et al.   Nature Chemical Biology

Engineered SAM synthetases for enzymatic generation of AdoMet analogs with photocaging groups and reversible DNA modification in cascade reactions

(2020) Freideriki Michailidou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly efficient expression of circular RNA aptamers in cells using autocatalytic transcripts

(2019) Jacob L. Litke et al.   NATURE BIOTECHNOLOGY

Reactivity of N3-Methyl-2′-Deoxyadenosine in Nucleosome Core Particles

(2019) Kun Yang et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Chemo‐enzymatic treatment of RNA to facilitate analyses

(2019) Nils Muthmann et al.   Wiley Interdisciplinary Reviews-RNA

How do cells cope with RNA damage and its consequences?

(2019) Liewei L. Yan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Direct in Vitro Selection of Trans-Acting Ribozymes for Posttranscriptional, Site-Specific, and Covalent Fluorescent Labeling of RNA

(2019) Mohammad Ghaem Maghami et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enzymatic or In Vivo Installation of Propargyl Groups in Combination with Click Chemistry for the Enrichment and Detection of Methyltransferase Target Sites in RNA

(2018) Katja Hartstock et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Reversible modification of DNA by methyltransferase-catalyzed transfer and light-triggered removal of photo-caging groups

(2018) Lea Anhäuser et al.   CHEMICAL COMMUNICATIONS

3′-End labeling of nucleic acids by a polymerase ribozyme

(2018) Biswajit Samanta et al.   NUCLEIC ACIDS RESEARCH

Repurposing enzymatic transferase reactions for targeted labeling and analysis of DNA and RNA

(2018) Miglė Tomkuvienė et al.   CURRENT OPINION IN BIOTECHNOLOGY

Methyltransferase-directed covalent coupling of fluorophores to DNA

(2017) Milena Helmer Lauer et al.   Chemical Science

Functional AdoMet Isosteres Resistant to Classical AdoMet Degradation Pathways

(2016) Tyler D. Huber et al.   ACS Chemical Biology

Facile synthesis of a 3-deazaadenosine phosphoramidite for RNA solid-phase synthesis

(2016) Elisabeth Mairhofer et al.   Beilstein Journal of Organic Chemistry

AdoMet analog synthesis and utilization: current state of the art

(2016) Tyler D Huber et al.   CURRENT OPINION IN BIOTECHNOLOGY

Pistol ribozyme adopts a pseudoknot fold facilitating site-specific in-line cleavage

(2016) Aiming Ren et al.   Nature Chemical Biology

In-Gel Imaging of RNA Processing Using Broccoli Reveals Optimal Aptamer Expression Strategies

(2015) Grigory S. Filonov et al.   CHEMISTRY & BIOLOGY

Bacteriophage strain typing by rapid single molecule analysis

(2015) Assaf Grunwald et al.   NUCLEIC ACIDS RESEARCH

Fluorescent RNA Labeling Using Self-Alkylating Ribozymes

(2014) Ashwani K. Sharma et al.   ACS Chemical Biology

Site-Specific Labeling of RNA at Internal Ribose Hydroxyl Groups: Terbium-Assisted Deoxyribozymes at Work

(2014) Lea Büttner et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Broccoli: Rapid Selection of an RNA Mimic of Green Fluorescent Protein by Fluorescence-Based Selection and Directed Evolution

(2014) Grigory S. Filonov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Electrophilic activity-based RNA probes reveal a self-alkylating RNA for RNA labeling

(2014) Richard I McDonald et al.   Nature Chemical Biology

Enhanced Chemical Stability of AdoMet Analogues for Improved Methyltransferase-Directed Labeling of DNA

(2013) Gražvydas Lukinavičius et al.   ACS Chemical Biology

A Chemo-Enzymatic Approach for Site-Specific Modification of the RNA Cap

(2013) Daniela Schulz et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Selenium-Based Click AdoMet Analogue for Versatile Substrate Labeling with Wild-Type Protein Methyltransferases

(2012) Sophie Willnow et al.   CHEMBIOCHEM

Se-Adenosyl-l-selenomethionine Cofactor Analogue as a Reporter of Protein Methylation

(2012) Ian R. Bothwell et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Profiling Genome-Wide Chromatin Methylation with Engineered Posttranslation Apparatus within Living Cells

(2012) Rui Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Programmable sequence-specific click-labeling of RNA using archaeal box C/D RNP methyltransferases

(2012) Miglė Tomkuvienė et al.   NUCLEIC ACIDS RESEARCH

Expanding the chemical scope of RNA:methyltransferases to site-specific alkynylation of RNA for click labeling

(2010) Y. Motorin et al.   NUCLEIC ACIDS RESEARCH

Single-Atom Imino Substitutions at A9 and A10 Reveal Distinct Effects on the Fold and Function of the Hairpin Ribozyme Catalytic Core

(2009) Robert C. Spitale et al.   BIOCHEMISTRY