Pan-cancer spatially resolved single-cell analysis reveals the crosstalk between cancer-associated fibroblasts and tumor microenvironment
出版年份 2023 全文链接
标题
Pan-cancer spatially resolved single-cell analysis reveals the crosstalk between cancer-associated fibroblasts and tumor microenvironment
作者
关键词
-
出版物
Molecular Cancer
Volume 22, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2023-10-13
DOI
10.1186/s12943-023-01876-x
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Single-cell analysis reveals prognostic fibroblast subpopulations linked to molecular and immunological subtypes of lung cancer
- (2023) Christopher J. Hanley et al. Nature Communications
- Single-cell dissection of cellular and molecular features underlying human cervical squamous cell carcinoma initiation and progression
- (2023) Chao Liu et al. Science Advances
- TGF-β Regulation of T Cells
- (2023) WanJun Chen Annual Review of Immunology
- Fibroblasts in cancer: Unity in heterogeneity
- (2023) Yash Chhabra et al. CELL
- Galectin-1: A Traditionally Immunosuppressive Protein Displays Context-Dependent Capacities
- (2023) Xizhi Yu et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- MIF inhibition alleviates vitiligo progression by suppressing CD8+ T cell activation and proliferation
- (2023) Jianru Chen et al. JOURNAL OF PATHOLOGY
- Extracellular matrix remodeling in tumor progression and immune escape: from mechanisms to treatments
- (2023) Zhennan Yuan et al. Molecular Cancer
- Roles of cancer-associated fibroblasts (CAFs) in anti- PD-1/PD-L1 immunotherapy for solid cancers
- (2023) Liping Pei et al. Molecular Cancer
- Targeting angiogenesis in oncology, ophthalmology and beyond
- (2023) Yihai Cao et al. NATURE REVIEWS DRUG DISCOVERY
- Single-cell transcriptome profiling of the stepwise progression of head and neck cancer
- (2023) Ji-Hye Choi et al. Nature Communications
- Tumor microenvironment remodeling after neoadjuvant immunotherapy in non-small cell lung cancer revealed by single-cell RNA sequencing
- (2023) Junjie Hu et al. Genome Medicine
- Harnessing type I interferon-mediated immunity to target malignant brain tumors
- (2023) Juhee Lim et al. Frontiers in Immunology
- Basement membrane promotes tumor development by attenuating T cell activation
- (2022) Xiangming Liu et al. Journal of Molecular Cell Biology
- ‘Reverse Warburg effect’ of cancer‑associated fibroblasts (Review)
- (2022) Lin Liang et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Spatial charting of single-cell transcriptomes in tissues
- (2022) Runmin Wei et al. NATURE BIOTECHNOLOGY
- Single-Cell RNA Sequencing Reveals the Tissue Architecture in Human High-Grade Serous Ovarian Cancer
- (2022) Junfen Xu et al. CLINICAL CANCER RESEARCH
- Cancer-associated fibroblasts: Vital suppressors of the immune response in the tumor microenvironment
- (2022) Xuan Xiang et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Recent progress on vascular endothelial growth factor receptor inhibitors with dual targeting capabilities for tumor therapy
- (2022) Yun Liu et al. Journal of Hematology & Oncology
- Cancer cell states recur across tumor types and form specific interactions with the tumor microenvironment
- (2022) Dalia Barkley et al. NATURE GENETICS
- A single-cell atlas of the multicellular ecosystem of primary and metastatic hepatocellular carcinoma
- (2022) Yiming Lu et al. Nature Communications
- Knowledge-graph-based cell-cell communication inference for spatially resolved transcriptomic data with SpaTalk
- (2022) Xin Shao et al. Nature Communications
- Targeting the tumor stroma for cancer therapy
- (2022) Maosen Xu et al. Molecular Cancer
- The expanding vistas of spatial transcriptomics
- (2022) Luyi Tian et al. NATURE BIOTECHNOLOGY
- Major pathways involved in macrophage polarization in cancer
- (2022) Clément Kerneur et al. Frontiers in Immunology
- Decoding Strategies to Evade Immunoregulators Galectin-1, -3, and -9 and Their Ligands as Novel Therapeutics in Cancer Immunotherapy
- (2022) Lee Seng Lau et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Liver tumour immune microenvironment subtypes and neutrophil heterogeneity
- (2022) Ruidong Xue et al. NATURE
- Pan-cancer single-cell analysis reveals the heterogeneity and plasticity of cancer-associated fibroblasts in the tumor microenvironment
- (2022) Han Luo et al. Nature Communications
- A single-cell analysis reveals tumor heterogeneity and immune environment of acral melanoma
- (2022) Chao Zhang et al. Nature Communications
- Systematic single-cell pathway analysis to characterize early T cell activation
- (2022) Jack A. Bibby et al. Cell Reports
- Delineating copy number and clonal substructure in human tumors from single-cell transcriptomes
- (2021) Ruli Gao et al. NATURE BIOTECHNOLOGY
- Implication of cancer associated fibroblast subtypes on cancer pathogenesis, prognosis, and immunotherapy resistance
- (2021) Phillip M Galbo et al. CLINICAL CANCER RESEARCH
- Type I interferon activating type I dendritic cells for anti-tumor immunity
- (2021) Yong Liang et al. CLINICAL CANCER RESEARCH
- Inference and analysis of cell-cell communication using CellChat
- (2021) Suoqin Jin et al. Nature Communications
- ShinyCell: simple and sharable visualization of single-cell gene expression data
- (2021) John F Ouyang et al. BIOINFORMATICS
- Fibroblast-macrophage reciprocal interactions in health, fibrosis, and cancer
- (2021) Matthew B. Buechler et al. IMMUNITY
- A single-cell map of intratumoral changes during anti-PD1 treatment of patients with breast cancer
- (2021) Ayse Bassez et al. NATURE MEDICINE
- Anti-angiogenic agents — overcoming tumour endothelial cell anergy and improving immunotherapy outcomes
- (2021) Zowi R. Huinen et al. Nature Reviews Clinical Oncology
- Conserved pan-cancer microenvironment subtypes predict response to immunotherapy
- (2021) Alexander Bagaev et al. CANCER CELL
- Mitogen‐activated protein kinase activity drives cell trajectories in colorectal cancer
- (2021) Florian Uhlitz et al. EMBO Molecular Medicine
- A single-cell and spatially resolved atlas of human breast cancers
- (2021) Sunny Z. Wu et al. NATURE GENETICS
- Spatiotemporal Immune Landscape of Colorectal Cancer Liver Metastasis at Single-Cell Level
- (2021) Yingcheng Wu et al. Cancer Discovery
- Cancer biology deciphered by single-cell transcriptomic sequencing
- (2021) Yanmeng Li et al. Protein & Cell
- Matrix Stiffness Induces Pericyte-Fibroblast Transition Through YAP Activation
- (2021) Feng Feng et al. Frontiers in Pharmacology
- Recombinant Mycobacterium smegmatis delivering a fusion protein of human macrophage migration inhibitory factor (MIF) and IL-7 exerts an anticancer effect by inducing an immune response against MIF in a tumor-bearing mouse model
- (2021) Hyein Jeong et al. Journal for ImmunoTherapy of Cancer
- Single-cell analysis of pancreatic ductal adenocarcinoma identifies a novel fibroblast subtype associated with poor prognosis but better immunotherapy response
- (2021) Yu Wang et al. Cell Discovery
- Galectins as Emerging Glyco-Checkpoints and Therapeutic Targets in Glioblastoma
- (2021) Guillermo A. Videla-Richardson et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Pan-cancer single-cell landscape of tumor-infiltrating T cells
- (2021) Liangtao Zheng et al. SCIENCE
- Single-cell transcriptomic analysis of the tumor ecosystems underlying initiation and progression of papillary thyroid carcinoma
- (2021) Weilin Pu et al. Nature Communications
- Comprehensive analysis of spatial architecture in primary liver cancer
- (2021) Rui Wu et al. Science Advances
- GeneSwitches: Ordering gene-expression and functional events in single-cell experiments
- (2020) Elaine Y Cao et al. BIOINFORMATICS
- Tertiary lymphoid structures improve immunotherapy and survival in melanoma
- (2020) Rita Cabrita et al. NATURE
- KLF16 Affects the MYC Signature and Tumor Growth in Prostate Cancer
- (2020) Jun Zhang et al. OncoTargets and Therapy
- Identification of Distinct Immune Subtypes in Colorectal Cancer Based on the Stromal Compartment
- (2020) Rongfang Shen et al. Frontiers in Oncology
- Emergence of a High-Plasticity Cell State during Lung Cancer Evolution
- (2020) Nemanja Despot Marjanovic et al. CANCER CELL
- A scalable SCENIC workflow for single-cell gene regulatory network analysis
- (2020) Bram Van de Sande et al. Nature Protocols
- Single-cell RNA sequencing highlights the role of inflammatory cancer-associated fibroblasts in bladder urothelial carcinoma
- (2020) Zhaohui Chen et al. Nature Communications
- Distinct Immune Cell Populations Define Response to Anti-PD-1 Monotherapy and Anti-PD-1/Anti-CTLA-4 Combined Therapy
- (2019) Tuba N. Gide et al. CANCER CELL
- Tumor Mutational Burden and Efficacy of Nivolumab Monotherapy and in Combination with Ipilimumab in Small-Cell Lung Cancer
- (2019) Matthew D. Hellmann et al. CANCER CELL
- TISIDB: an integrated repository portal for tumor-immune system interactions
- (2019) Beibei Ru et al. BIOINFORMATICS
- WebGestalt 2019: gene set analysis toolkit with revamped UIs and APIs
- (2019) Yuxing Liao et al. NUCLEIC ACIDS RESEARCH
- DoubletFinder: Doublet Detection in Single-Cell RNA Sequencing Data Using Artificial Nearest Neighbors
- (2019) Christopher S. McGinnis et al. Cell Systems
- Fast, sensitive and accurate integration of single-cell data with Harmony
- (2019) Ilya Korsunsky et al. NATURE METHODS
- Type I Interferons and Cancer: An Evolving Story Demanding Novel Clinical Applications
- (2019) Eleonora Aricò et al. Cancers
- Slingshot: cell lineage and pseudotime inference for single-cell transcriptomics
- (2018) Kelly Street et al. BMC GENOMICS
- Single-Cell Map of Diverse Immune Phenotypes in the Breast Tumor Microenvironment
- (2018) Elham Azizi et al. CELL
- Integrating single-cell transcriptomic data across different conditions, technologies, and species
- (2018) Andrew Butler et al. NATURE BIOTECHNOLOGY
- Perturbation-response genes reveal signaling footprints in cancer gene expression
- (2018) Michael Schubert et al. Nature Communications
- Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response
- (2018) Peng Jiang et al. NATURE MEDICINE
- Maftools: efficient and comprehensive analysis of somatic variants in cancer
- (2018) Anand Mayakonda et al. GENOME RESEARCH
- Revealing the Critical Regulators of Cell Identity in the Mouse Cell Atlas
- (2018) Shengbao Suo et al. Cell Reports
- Identification of an Immune-specific Class of Hepatocellular Carcinoma, Based on Molecular Features
- (2017) Daniela Sia et al. GASTROENTEROLOGY
- IFN-γ–related mRNA profile predicts clinical response to PD-1 blockade
- (2017) Mark Ayers et al. JOURNAL OF CLINICAL INVESTIGATION
- KLF4-dependent perivascular cell plasticity mediates pre-metastatic niche formation and metastasis
- (2017) Meera Murgai et al. NATURE MEDICINE
- Integrated molecular analysis of tumor biopsies on sequential CTLA-4 and PD-1 blockade reveals markers of response and resistance
- (2017) Whijae Roh et al. Science Translational Medicine
- Type I Interferon in Chronic Virus Infection and Cancer
- (2017) Laura M. Snell et al. TRENDS IN IMMUNOLOGY
- CDX2 is involved in microRNA‑associated inflammatory carcinogenesis in gastric cancer
- (2017) Motonobu Saito et al. Oncology Letters
- Pericyte–fibroblast transition promotes tumor growth and metastasis
- (2016) Kayoko Hosaka et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Somatic Mutations and Neoepitope Homology in Melanomas Treated with CTLA-4 Blockade
- (2016) Tavi Nathanson et al. Cancer Immunology Research
- Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity
- (2015) Michael S. Rooney et al. CELL
- Stromal miR-200s contribute to breast cancer cell invasion through CAF activation and ECM remodeling
- (2015) X Tang et al. CELL DEATH AND DIFFERENTIATION
- The Transcription Factor NFAT Promotes Exhaustion of Activated CD8 + T Cells
- (2015) Gustavo J. Martinez et al. IMMUNITY
- TCGAbiolinks: an R/Bioconductor package for integrative analysis of TCGA data
- (2015) Antonio Colaprico et al. NUCLEIC ACIDS RESEARCH
- NFATc1 Regulates PD-1 Expression upon T Cell Activation
- (2014) K. J. Oestreich et al. JOURNAL OF IMMUNOLOGY
- GSVA: gene set variation analysis for microarray and RNA-Seq data
- (2013) Sonja Hänzelmann et al. BMC BIOINFORMATICS
- ‘Cancer associated fibroblasts’ – more than meets the eye
- (2013) Shalom Madar et al. TRENDS IN MOLECULAR MEDICINE
- Inferring tumour purity and stromal and immune cell admixture from expression data
- (2013) Kosuke Yoshihara et al. Nature Communications
- Robust rank aggregation for gene list integration and meta-analysis
- (2012) Raivo Kolde et al. BIOINFORMATICS
- Therapeutic applications of macrophage colony-stimulating factor-1 (CSF-1) and antagonists of CSF-1 receptor (CSF-1R) signaling
- (2011) D. A. Hume et al. BLOOD
- GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers
- (2011) Craig H Mermel et al. GENOME BIOLOGY
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