Liver tumour immune microenvironment subtypes and neutrophil heterogeneity

Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches

(2022) Martin Guilliams et al.   CELL

CellRank for directed single-cell fate mapping

(2022) Marius Lange et al.   NATURE METHODS

Neutrophil phenotypes and functions in cancer: A consensus statement

(2022) Daniela F. Quail et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Molecular correlates of clinical response and resistance to atezolizumab in combination with bevacizumab in advanced hepatocellular carcinoma

(2022) Andrew X. Zhu et al.   NATURE MEDICINE

Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis

(2021) Chang Cui et al.   CELL

Conserved pan-cancer microenvironment subtypes predict response to immunotherapy

(2021) Alexander Bagaev et al.   CANCER CELL

Single-cell atlas of tumor cell evolution in response to therapy in hepatocellular carcinoma and intrahepatic cholangiocarcinoma

(2021) Lichun Ma et al.   JOURNAL OF HEPATOLOGY

A single-cell and spatially resolved atlas of human breast cancers

(2021) Sunny Z. Wu et al.   NATURE GENETICS

Targeting multiple cell death pathways extends the shelf life and preserves the function of human and mouse neutrophils for transfusion

(2021) Yuping Fan et al.   Science Translational Medicine

IDH Mutation Subgroup Status Associates with Intratumor Heterogeneity and the Tumor Microenvironment in Intrahepatic Cholangiocarcinoma

(2021) Xiao Xiang et al.   Advanced Science

Comprehensive analysis of spatial architecture in primary liver cancer

(2021) Rui Wu et al.   Science Advances

Single-cell transcriptional diversity is a hallmark of developmental potential

(2020) Gunsagar S. Gulati et al.   SCIENCE

Single-Cell Analyses Inform Mechanisms of Myeloid-Targeted Therapies in Colon Cancer

(2020) Lei Zhang et al.   CELL

Single-cell technologies in hepatology: new insights into liver biology and disease pathogenesis

(2020) Prakash Ramachandran et al.   Nature Reviews Gastroenterology & Hepatology

Atezolizumab plus Bevacizumab in Unresectable Hepatocellular Carcinoma

(2020) Richard S. Finn et al.   NEW ENGLAND JOURNAL OF MEDICINE

Durable and controlled depletion of neutrophils in mice

(2020) Gael Boivin et al.   Nature Communications

Coordinated Cellular Neighborhoods Orchestrate Antitumoral Immunity at the Colorectal Cancer Invasive Front

(2020) Christian M. Schürch et al.   CELL

Single-cell transcriptomic architecture and intercellular crosstalk of human intrahepatic cholangiocarcinoma

(2020) Min Zhang et al.   JOURNAL OF HEPATOLOGY

DNA of neutrophil extracellular traps promotes cancer metastasis via CCDC25

(2020) Linbin Yang et al.   NATURE

Single-cell transcriptome profiling reveals neutrophil heterogeneity in homeostasis and infection

(2020) Xuemei Xie et al.   NATURE IMMUNOLOGY

Single-cell analysis uncovers fibroblast heterogeneity and criteria for fibroblast and mural cell identification and discrimination

(2020) Lars Muhl et al.   Nature Communications

Co-option of Neutrophil Fates by Tissue Environments

(2020) Iván Ballesteros et al.   CELL

Onco-fetal Reprogramming of Endothelial Cells Drives Immunosuppressive Macrophages in Hepatocellular Carcinoma

(2020) Ankur Sharma et al.   CELL

Osteopontin Expression Identifies a Subset of Recruited Macrophages Distinct from Kupffer Cells in the Fatty Liver

(2020) Anneleen Remmerie et al.   IMMUNITY

Single-cell landscape of the ecosystem in early-relapse hepatocellular carcinoma

(2020) Yunfan Sun et al.   CELL

IL1β promotes immune suppression in the tumor microenvironment independent of the inflammasome and gasdermin D

(2020) Mate Kiss et al.   Cancer Immunology Research

Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage

(2019) Dvir Aran et al.   NATURE IMMUNOLOGY

Neutrophils escort circulating tumour cells to enable cell cycle progression

(2019) Barbara Maria Szczerba et al.   NATURE

Genomic and Transcriptomic Profiling of Combined Hepatocellular and Intrahepatic Cholangiocarcinoma Reveals Distinct Molecular Subtypes

(2019) Ruidong Xue et al.   CANCER CELL

Single-Cell Transcriptomics of Human and Mouse Lung Cancers Reveals Conserved Myeloid Populations across Individuals and Species

(2019) Rapolas Zilionis et al.   IMMUNITY

Neutrophils Driving Unconventional T Cells Mediate Resistance against Murine Sarcomas and Selected Human Tumors

(2019) Andrea Ponzetta et al.   CELL

Single-Cell Multi-omic Integration Compares and Contrasts Features of Brain Cell Identity

(2019) Joshua D. Welch et al.   CELL

A human liver cell atlas reveals heterogeneity and epithelial progenitors

(2019) Nadim Aizarani et al.   NATURE

Tumour-associated neutrophils in patients with cancer

(2019) Merav E. Shaul et al.   Nature Reviews Clinical Oncology

Tumor Cell Biodiversity Drives Microenvironmental Reprogramming in Liver Cancer

(2019) Lichun Ma et al.   CANCER CELL

Landscape and Dynamics of Single Immune Cells in Hepatocellular Carcinoma

(2019) Qiming Zhang et al.   CELL

The Immune Landscape of Cancer

(2018) Vésteinn Thorsson et al.   IMMUNITY

Understanding the tumor immune microenvironment (TIME) for effective therapy

(2018) Mikhail Binnewies et al.   NATURE MEDICINE

Necroptosis microenvironment directs lineage commitment in liver cancer

(2018) Marco Seehawer et al.   NATURE

Single-cell reconstruction of the early maternal–fetal interface in humans

(2018) Roser Vento-Tormo et al.   NATURE

SCENIC: single-cell regulatory network inference and clustering

(2017) Sara Aibar et al.   NATURE METHODS

Single-cell mRNA quantification and differential analysis with Census

(2017) Xiaojie Qiu et al.   NATURE METHODS

Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH -Mutant Molecular Profiles

(2017) Farshad Farshidfar et al.   Cell Reports

Neutrophils support lung colonization of metastasis-initiating breast cancer cells

(2015) Stefanie K. Wculek et al.   NATURE

Spatial reconstruction of single-cell gene expression data

(2015) Rahul Satija et al.   NATURE BIOTECHNOLOGY

Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer

(2013) C. Feig et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA