Advances in vaccine development for cancer prevention and treatment in Lynch Syndrome
出版年份 2023 全文链接
标题
Advances in vaccine development for cancer prevention and treatment in Lynch Syndrome
作者
关键词
-
出版物
MOLECULAR ASPECTS OF MEDICINE
Volume 93, Issue -, Pages 101204
出版商
Elsevier BV
发表日期
2023-07-20
DOI
10.1016/j.mam.2023.101204
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Worldwide prevalence of Lynch syndrome in patients with colorectal cancer: Systematic review and meta-analysis
- (2022) Nadine Abu-Ghazaleh et al. GENETICS IN MEDICINE
- Risk assessment and genetic counseling for Lynch syndrome – Practice resource of the National Society of Genetic Counselors and the Collaborative Group of the Americas on Inherited Gastrointestinal Cancer
- (2022) Spring Holter et al. Journal of Genetic Counseling
- B2M and JAK1/2–mutated MSI-H Colorectal Carcinomas Can Benefit From Anti-PD-1 Therapy
- (2022) Chenzhi Zhang et al. JOURNAL OF IMMUNOTHERAPY
- Immunogenicity and therapeutic targeting of a public neoantigen derived from mutated PIK3CA
- (2022) Smita S. Chandran et al. NATURE MEDICINE
- Molecular signatures of antitumor neoantigen-reactive T cells from metastatic human cancers
- (2022) Frank J. Lowery et al. SCIENCE
- Comparative molecular genomic analyses of a spontaneous rhesus macaque model of mismatch repair-deficient colorectal cancer
- (2022) Nejla Ozirmak Lermi et al. PLoS Genetics
- Neoantigen‐based cancer vaccination using chimeric RNA‐loaded dendritic cell‐derived extracellular vesicles
- (2022) Xiao Xiong et al. Journal of Extracellular Vesicles
- Tumor-derived extracellular vesicles in melanoma immune response and immunotherapy
- (2022) Qiujun Zhou et al. BIOMEDICINE & PHARMACOTHERAPY
- mRNA vaccine: a potential therapeutic strategy
- (2021) Yang Wang et al. Molecular Cancer
- CD4 T-Cell Exhaustion: Does It Exist and What Are Its Roles in Cancer?
- (2021) Alexandra M. Miggelbrink et al. CLINICAL CANCER RESEARCH
- The tangled history of mRNA vaccines
- (2021) Elie Dolgin NATURE
- Immunology of Lynch Syndrome
- (2021) Danielle M. Pastor et al. Current Oncology Reports
- Preventive Cancer Vaccine Based on Neoantigens Gets Put to the Test
- (2021) Alla Katsnelson ACS Central Science
- Identification of neoantigen-reactive T lymphocytes in the peripheral blood of a patient with glioblastoma
- (2021) Vid Leko et al. Journal for ImmunoTherapy of Cancer
- Direct identification of neoantigen-specific TCRs from tumor specimens by high-throughput single-cell sequencing
- (2021) Yong-Chen Lu et al. Journal for ImmunoTherapy of Cancer
- Recurrent Frameshift Neoantigen Vaccine Elicits Protective Immunity With Reduced Tumor Burden and Improved Overall Survival in a Lynch Syndrome Mouse Model
- (2021) Johannes Gebert et al. GASTROENTEROLOGY
- Mismatch repair deficiency: The what, how and why it is important
- (2021) Maria C. Olave et al. GENES CHROMOSOMES & CANCER
- High-throughput and high-dimensional single-cell analysis of antigen-specific CD8+ T cells
- (2021) Ke-Yue Ma et al. NATURE IMMUNOLOGY
- 410 Phase I interim study results of Nous-209, an off-the-shelf immunotherapy, with pembrolizumab, for the treatment of tumors with a deficiency in mismatch repair/microsatellite instability (dMMR/MSI)
- (2021) Michael Overman et al. Journal for ImmunoTherapy of Cancer
- The Different Immune Profiles of Normal Colonic Mucosa in Cancer-Free Lynch Syndrome Carriers and Lynch Syndrome Colorectal Cancer Patients
- (2021) Lena Bohaumilitzky et al. GASTROENTEROLOGY
- NetMHCpan-4.1 and NetMHCIIpan-4.0: improved predictions of MHC antigen presentation by concurrent motif deconvolution and integration of MS MHC eluted ligand data
- (2020) Birkir Reynisson et al. NUCLEIC ACIDS RESEARCH
- A genetic vaccine encoding shared cancer neoantigens to treat tumors with Microsatellite Instability.
- (2020) Guido Leoni et al. CANCER RESEARCH
- A Frameshift Peptide Neoantigen-Based Vaccine for Mismatch Repair-Deficient Cancers: A Phase I/IIa Clinical Trial
- (2020) Matthias Kloor et al. CLINICAL CANCER RESEARCH
- Naproxen chemoprevention promotes immune activation in Lynch syndrome colorectal mucosa
- (2020) Laura Reyes-Uribe et al. GUT
- Effect of aspirin on cancer incidence and mortality in older adults
- (2020) John J McNeil et al. JNCI-Journal of the National Cancer Institute
- Evaluation of T-Cell Responses Against Shared Melanoma Associated Antigens and Predicted Neoantigens in Cutaneous Melanoma Patients Treated With the CSF-470 Allogeneic Cell Vaccine Plus BCG and GM-CSF
- (2020) Enrique Podaza et al. Frontiers in Immunology
- Implications of Hereditary Origin on the Immune Phenotype of Mismatch Repair-Deficient Cancers: Systematic Literature Review
- (2020) Lena Bohaumilitzky et al. Journal of Clinical Medicine
- A Phase Ib Trial of Personalized Neoantigen Therapy Plus Anti-PD-1 in Patients with Advanced Melanoma, Non-small Cell Lung Cancer, or Bladder Cancer
- (2020) Patrick A. Ott et al. CELL
- mRNA vaccine–induced neoantigen-specific T cell immunity in patients with gastrointestinal cancer
- (2020) Gal Cafri et al. JOURNAL OF CLINICAL INVESTIGATION
- The shared frameshift mutation landscape of microsatellite-unstable cancers suggests immunoediting during tumor evolution
- (2020) Alexej Ballhausen et al. Nature Communications
- Shared Immunogenic Poly-Epitope Frameshift Mutations in Microsatellite Unstable Tumors
- (2020) Vladimir Roudko et al. CELL
- Engineering approaches for studying immune-tumor cell interactions and immunotherapy
- (2020) Sarah E. Shelton et al. iScience
- Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database
- (2019) Mev Dominguez-Valentin et al. GENETICS IN MEDICINE
- Adenoviral vaccine targeting multiple neoantigens as strategy to eradicate large tumors combined with checkpoint blockade
- (2019) Anna Morena D’Alise et al. Nature Communications
- Determinants for Neoantigen Identification
- (2019) Andrea Garcia-Garijo et al. Frontiers in Immunology
- CD4+ T cells indirectly kill tumor cells via induction of cytotoxic macrophages in mouse models
- (2019) Bjarne Bogen et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Immune Activation in Mismatch Repair Deficient Carcinogenesis: More Than Just Mutational Rate
- (2019) Jason A. Willis et al. CLINICAL CANCER RESEARCH
- Late-differentiated effector neoantigen-specific CD8+ T cells are enriched in peripheral blood of non-small cell lung carcinoma patients responding to atezolizumab treatment
- (2019) Michael Fehlings et al. Journal for ImmunoTherapy of Cancer
- Precision Treatment and Prevention of Colorectal Cancer—Hope or Hype?
- (2019) Charles Muller et al. GASTROENTEROLOGY
- pTuneos: prioritizing tumor neoantigens from next-generation sequencing data
- (2019) Chi Zhou et al. Genome Medicine
- Neoantigens and genome instability: impact on immunogenomic phenotypes and immunotherapy response
- (2019) Elaine R. Mardis Genome Medicine
- Neoantigen Dissimilarity to the Self-Proteome Predicts Immunogenicity and Response to Immune Checkpoint Blockade
- (2019) Lee P. Richman et al. Cell Systems
- High-Throughput Prediction of MHC Class I and II Neoantigens with MHCnuggets
- (2019) Xiaoshan M. Shao et al. Cancer Immunology Research
- In Immunopeptidomics We Need a Sniper Instead of a Shotgun
- (2018) Pouya Faridi et al. PROTEOMICS
- Optimized Peptide–MHC Multimer Protocols for Detection and Isolation of Autoimmune T-Cells
- (2018) Garry Dolton et al. Frontiers in Immunology
- MHCflurry: Open-Source Class I MHC Binding Affinity Prediction
- (2018) Timothy J. O'Donnell et al. Cell Systems
- Immune Profiling of Premalignant Lesions in Patients With Lynch Syndrome
- (2018) Kyle Chang et al. JAMA Oncology
- Immunoprofiles of colorectal cancer from Lynch syndrome
- (2018) Joanna Walkowska et al. OncoImmunology
- Actively personalized vaccination trial for newly diagnosed glioblastoma
- (2018) Norbert Hilf et al. NATURE
- Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial
- (2018) Derin B. Keskin et al. NATURE
- Immune Functional Assays, From Custom to Standardized Tests for Precision Medicine
- (2018) Chloé Albert-Vega et al. Frontiers in Immunology
- Somatic mutations of the coding microsatellites within the beta-2-microglobulin gene in mismatch repair-deficient colorectal cancers and adenomas
- (2017) Mark Clendenning et al. Familial Cancer
- Mass Spectrometry Profiling of HLA-Associated Peptidomes in Mono-allelic Cells Enables More Accurate Epitope Prediction
- (2017) Jennifer G. Abelin et al. IMMUNITY
- Emerging Concepts in TCR Specificity: Rationalizing and (Maybe) Predicting Outcomes
- (2017) Nishant K. Singh et al. JOURNAL OF IMMUNOLOGY
- Insertion-and-deletion-derived tumour-specific neoantigens and the immunogenic phenotype: a pan-cancer analysis
- (2017) Samra Turajlic et al. LANCET ONCOLOGY
- Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
- (2017) Ugur Sahin et al. NATURE
- VarScan2 analysis of de novo variants in monozygotic twins discordant for schizophrenia
- (2017) Emma Reble et al. PSYCHIATRIC GENETICS
- A molecular portrait of microsatellite instability across multiple cancers
- (2017) Isidro Cortes-Ciriano et al. Nature Communications
- Mutation of TGFβ-RII eliminates NSAID cancer chemoprevention
- (2017) Juana Martín-López et al. Oncotarget
- Large-scale detection of antigen-specific T cells using peptide-MHC-I multimers labeled with DNA barcodes
- (2016) Amalie Kai Bentzen et al. NATURE BIOTECHNOLOGY
- Classification and characterization of microsatellite instability across 18 cancer types
- (2016) Ronald J Hause et al. NATURE MEDICINE
- T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer
- (2016) Eric Tran et al. NEW ENGLAND JOURNAL OF MEDICINE
- VarDict: a novel and versatile variant caller for next-generation sequencing in cancer research
- (2016) Zhongwu Lai et al. NUCLEIC ACIDS RESEARCH
- Global proteogenomic analysis of human MHC class I-associated peptides derived from non-canonical reading frames
- (2016) Céline M. Laumont et al. Nature Communications
- pVAC-Seq: A genome-guided in silico approach to identifying tumor neoantigens
- (2016) Jasreet Hundal et al. Genome Medicine
- Eukaryotic Mismatch Repair in Relation to DNA Replication
- (2015) Thomas A. Kunkel et al. Annual Review of Genetics
- Cancer incidence and survival in Lynch syndrome patients receiving colonoscopic and gynaecological surveillance: first report from the prospective Lynch syndrome database
- (2015) Pål Møller et al. GUT
- PD-1 Blockade in Tumors with Mismatch-Repair Deficiency
- (2015) Dung T. Le et al. NEW ENGLAND JOURNAL OF MEDICINE
- OptiType: precision HLA typing from next-generation sequencing data
- (2014) András Szolek et al. BIOINFORMATICS
- A multiplex method for the detection of serum antibodies against in silico-predicted tumor antigens
- (2014) Miriam Reuschenbach et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Association of high CD4-positive T cell infiltration with mutations in HLA class II-regulatory genes in microsatellite-unstable colorectal cancer
- (2014) Eva-Maria Surmann et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Guidelines on Genetic Evaluation and Management of Lynch Syndrome: A Consensus Statement by the US Multi-Society Task Force on Colorectal Cancer
- (2014) Francis M. Giardiello et al. GASTROENTEROLOGY
- Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing
- (2014) Mahesh Yadav et al. NATURE
- The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints
- (2014) Nicolas J. Llosa et al. Cancer Discovery
- Oncology Meets Immunology: The Cancer-Immunity Cycle
- (2013) Daniel S. Chen et al. IMMUNITY
- Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples
- (2013) Kristian Cibulskis et al. NATURE BIOTECHNOLOGY
- Prognostic Significance of Tumor-Infiltrating Lymphocytes for Patients With Colorectal Cancer
- (2012) Jae Hyuk Lee ARCHIVES OF SURGERY
- T cell responses against microsatellite instability-induced frameshift peptides and influence of regulatory T cells in colorectal cancer
- (2012) Kathrin Bauer et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Microsatellite Instability and DNA Mismatch Repair Protein Deficiency in Lynch Syndrome Colorectal Polyps
- (2012) M. B. Yurgelun et al. Cancer Prevention Research
- Infiltration of Lynch Colorectal Cancers by Activated Immune Cells Associates with Early Staging of the Primary Tumor and Absence of Lymph Node Metastases
- (2012) Noel F.C.C. de Miranda et al. CLINICAL CANCER RESEARCH
- Risks of Less Common Cancers in Proven Mutation Carriers With Lynch Syndrome
- (2012) Christoph Engel et al. JOURNAL OF CLINICAL ONCOLOGY
- Prevalence of mismatch repair-deficient crypt foci in Lynch syndrome: a pathological study
- (2012) Matthias Kloor et al. LANCET ONCOLOGY
- SomaticSniper: identification of somatic point mutations in whole genome sequencing data
- (2011) David E. Larson et al. BIOINFORMATICS
- Comparison between universal molecular screening for Lynch syndrome and revised Bethesda guidelines in a large population-based cohort of patients with colorectal cancer
- (2011) Lucía Pérez-Carbonell et al. GUT
- Colorectal cancer prognosis depends on T-cell infiltration and molecular characteristics of the tumor
- (2011) Anna M Dahlin et al. MODERN PATHOLOGY
- De NovoSequencing and Homology Searching
- (2011) Bin Ma et al. MOLECULAR & CELLULAR PROTEOMICS
- Repetitive DNA and next-generation sequencing: computational challenges and solutions
- (2011) Todd J. Treangen et al. NATURE REVIEWS GENETICS
- NetCTLpan: pan-specific MHC class I pathway epitope predictions
- (2010) Thomas Stranzl et al. IMMUNOGENETICS
- Microsatellite instability in colorectal cancer—the stable evidence
- (2010) Eduardo Vilar et al. Nature Reviews Clinical Oncology
- Serum antibodies against frameshift peptides in microsatellite unstable colorectal cancer patients with Lynch syndrome
- (2009) Miriam Reuschenbach et al. Familial Cancer
- The cancer vaccine roller coaster
- (2009) Bruce Goldman et al. NATURE BIOTECHNOLOGY
- Fas Ligand Expression in Lynch Syndrome-Associated Colorectal Tumours
- (2009) Jan J. Koornstra et al. PATHOLOGY & ONCOLOGY RESEARCH
- Immune Response Against Frameshift-Induced Neopeptides in HNPCC Patients and Healthy HNPCC Mutation Carriers
- (2008) Yvette Schwitalle et al. GASTROENTEROLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now